DOI: 10.1038/nm791. Automated subcellular localization and quantification of protein expression in tissue microarrays

Automated subcellular localization and quantification of protein expression in tissue microarrays

10.1038/nm791

Crossref journal-article

Springer Science and Business Media LLC

Nature Medicine (297)

Authors 3

Robert L. Camp (first)
Gina G. Chung (additional)
David L. Rimm (additional)

References 19 Referenced 643

Tarnok, A. & Gerstner, A.O. Clinical applications of laser scanning cytometry. Cytometry 50, 133–143 (2002). (10.1002/cyto.10099) / Cytometry by A Tarnok (2002)
Robinson, J.P. Principles of confocal microscopy. Methods Cell Biol. 63, 89–106 (2001). (10.1016/S0091-679X(01)63008-5) / Methods Cell Biol. by JP Robinson (2001)
Rao, J., Seligson, D. & Hemstreet, G.P. Protein expression analysis using quantitative fluorescence image analysis on tissue microarray slides. Biotechniques 32, 924–932 (2002). (10.2144/02324pt04) / Biotechniques by J Rao (2002)
Bacus, S. et al. Potential use of image analysis for the evaluation of cellular predicting factors for therapeutic response in breast cancers. Anal. Quant. Cytol. Histol. 19, 316–328 (1997). / Anal. Quant. Cytol. Histol. by S Bacus (1997)
Kallioniemi, O.P., Wagner, U., Kononen, J. & Sauter, G. Tissue microarray technology for high-throughput molecular profiling of cancer. Hum. Mol. Genet. 10, 657–662 (2001). (10.1093/hmg/10.7.657) / Hum. Mol. Genet. by OP Kallioniemi (2001)
Kononen, J. et al. Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nature Med. 4, 844–847 (1998). (10.1038/nm0798-844) / Nature Med. by J Kononen (1998)
Rimm, D.L. et al. Tissue microarray: a new technology for amplification of tissue resources. Cancer J 7, 24–31 (2001). / Cancer J by DL Rimm (2001)
Osborne, C.K. et al. Estrogen receptor, a marker for human breast cancer differentiation and patient prognosis. Adv. Exp. Med. Biol. 138, 377–385 (1981). (10.1007/978-1-4615-7192-6_23) / Adv. Exp. Med. Biol. by CK Osborne (1981)
Wasson, J.H., Sox, H.C., Neff, R.K. & Goldman, L. Clinical prediction rules. Applications and methodological standards. N. Engl. J. Med. 313, 793–799 (1985). (10.1056/NEJM198509263131306) / N. Engl. J. Med. by JH Wasson (1985)
Kobayashi, M. et al. Nuclear translocation of β-catenin in colorectal cancer. Br. J. Cancer 82, 1689–1693 (2000). (10.1054/bjoc.1999.1112) / Br. J. Cancer by M Kobayashi (2000)
Provost, E. & Rimm, D.L. Controversies at the cytoplasmic face of the cadherin-based adhesion complex. Curr. Opin. Cell Biol. 11, 567–572 (1999). (10.1016/S0955-0674(99)00015-0) / Curr. Opin. Cell Biol. by E Provost (1999)
Morin, P.J. β-catenin signaling and cancer. Bioessays 21, 1021–1030 (1999). (10.1002/(SICI)1521-1878(199912)22:1<1021::AID-BIES6>3.0.CO;2-P) / Bioessays by PJ Morin (1999)
Peifer, M. & Polakis, P. Wnt signaling in oncogenesis and embryogenesis—a look outside the nucleus. Science 287, 1606–1609 (2000). (10.1126/science.287.5458.1606) / Science by M Peifer (2000)
Wong, C.M., Fan, S.T. & Ng, I.O. β-catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance. Cancer 92, 136–145 (2001). (10.1002/1097-0142(20010701)92:1<136::AID-CNCR1301>3.0.CO;2-R) / Cancer by CM Wong (2001)
Gunther, K. et al. Predictive value of nuclear β-catenin expression for the occurrence of distant metastases in rectal cancer. Dis. Colon Rectum 41, 1256–1261 (1998). (10.1007/BF02258226) / Dis. Colon Rectum by K Gunther (1998)
Maruyama, K. et al. Cytoplasmic β-catenin accumulation as a predictor of hematogenous metastasis in human colorectal cancer. Oncology 59, 302–309 (2000). (10.1159/000012187) / Oncology by K Maruyama (2000)
Hugh, T.J. et al. β-catenin expression in primary and metastatic colorectal carcinoma. Int. J. Cancer 82, 504–511 (1999). (10.1002/(SICI)1097-0215(19990812)82:4<504::AID-IJC6>3.0.CO;2-6) / Int. J. Cancer by TJ Hugh (1999)
Chung, G.G. et al. Tissue microarray analysis of β-catenin in colorectal cancer shows nuclear phospho-β-catenin is associated with a better prognosis. Clin. Cancer Res. 7, 4013–4020 (2001). / Clin. Cancer Res. by GG Chung (2001)
Lin, S.Y. et al. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nature Cell Biol. 3, 802–808 (2001). (10.1038/ncb0901-802) / Nature Cell Biol. by SY Lin (2001)

Dates

Type	When
Created	22 years, 9 months ago (Nov. 1, 2002, 9:12 a.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 6:32 p.m.)
Indexed	1 day, 18 hours ago (Aug. 29, 2025, 6:03 a.m.)
Issued	22 years, 10 months ago (Oct. 21, 2002)
Published	22 years, 10 months ago (Oct. 21, 2002)
Published Online	22 years, 10 months ago (Oct. 21, 2002)
Published Print	22 years, 9 months ago (Nov. 1, 2002)

Funders 0

None

BibTeX

@article{Camp_2002, title={Automated subcellular localization and quantification of protein expression in tissue microarrays}, volume={8}, ISSN={1546-170X}, url={http://dx.doi.org/10.1038/nm791}, DOI={10.1038/nm791}, number={11}, journal={Nature Medicine}, publisher={Springer Science and Business Media LLC}, author={Camp, Robert L. and Chung, Gina G. and Rimm, David L.}, year={2002}, month=oct, pages={1323–1328} }

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