Crossref
journal-article
Springer Science and Business Media LLC
Nature Medicine (297)
References
36
Referenced
170
-
Sherrington, R. et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375, 754–760 (1995).
(
10.1038/375754a0
) / Nature by R Sherrington (1995) -
Rogaev, E.I. et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775–778 (1995).
(
10.1038/376775a0
) / Nature by EI Rogaev (1995) -
Levy-Lahad, E. et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269, 973–977 (1995).
(
10.1126/science.7638622
) / Science by E Levy-Lahad (1995) -
Van Broeckhoven, C. Presenilins and Alzheimer disease. Nature Genet. 11, 230–232 (1995).
(
10.1038/ng1195-230
) / Nature Genet. by C Van Broeckhoven (1995) -
Lemere, C.A. et al. The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology. Nature Med. 2, 1146–1150 (1996).
(
10.1038/nm1096-1146
) / Nature Med. by CA Lemere (1996) -
Kang, J. et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733–736 (1987).
(
10.1038/325733a0
) / Nature by J Kang (1987) -
Selkoe, D.J., β-protein and the genetics of Alzheimer's disease. J. Biol. Chem. 271 18295–18298 (1996).
(
10.1074/jbc.271.31.18295
) / J. Biol. Chem. by DJ Selkoe (1996) -
Weidemann, A. et al. Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57, 115–126 (1989).
(
10.1016/0092-8674(89)90177-3
) / Cell by A Weidemann (1989) -
Esch, F.S. et al. Cleavage of amyloid β peptide during constitutive processing of its precursor. Science 248, 1122–1124 (1990).
(
10.1126/science.2111583
) / Science by FS Esch (1990) -
Haass, C. et al. Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature 359, 322–325 (1992).
(
10.1038/359322a0
) / Nature by C Haass (1992) -
Shoji, M. et al. Production of the Alzheimer amyloid beta protein by normal proteolytic processing. Science 258, 126–129 (1992).
(
10.1126/science.1439760
) / Science by M Shoji (1992) -
Suzuki, N. et al. An increased percentage of long amyloid β protein secreted by familial amyloid β protein precursor (βAPP717) mutants. Science 264, 1336–1340 (1994).
(
10.1126/science.8191290
) / Science by N Suzuki (1994) -
Jarrett, J.T., Berger, E.P. & Lansbury, P.T. Jr., The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease. Biochemistry 32, 4693–4697 (1993).
(
10.1021/bi00069a001
) / Biochemistry by JT Jarrett (1993) -
Citron, M. et al. Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production. Nature 360, 672–674 (1992).
(
10.1038/360672a0
) / Nature by M Citron (1992) -
Cai, X.D., Golde, T.E. & Younkin, S.G. Release of excess amyloid β protein from a mutant amyloid β protein precursor. Science 259, 514–516 (1993).
(
10.1126/science.8424174
) / Science by XD Cai (1993) -
Haass, C., Hung, A.Y., Selkoe, D. & Teplow, D.B. Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor. J. Biol. Chem. 269, 17741–17748 (1994).
(
10.1016/S0021-9258(17)32503-6
) / J. Biol. Chem. by C Haass (1994) -
Kovacs, D.M. et al. Alzheimer-associated presenilins 1 and 2: Neuronal expression in brain and localization to intra cellular membranes in mammalian cells. Nature Med. 2, 224–229 (1996).
(
10.1038/nm0296-224
) / Nature Med. by DM Kovacs (1996) -
Scheuner, D. et al. Secreted amyloid β-protein similar to that in the senile plaque of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nature Med. 2, 864–870 (1996).
(
10.1038/nm0896-864
) / Nature Med. by D Scheuner (1996) -
Duff, K. et al. Increased amyloid-b42 (43) in brains of mice expressing mutant presenilin 1. Nature 383, 710–713 (1996).
(
10.1038/383710a0
) / Nature by K Duff (1996) -
Thinakaran, G. et al. Endoproteoysis of presenilin 1 and acumulation of processed derivatives in vivo. Neuron 17, 1–20 (1996).
(
10.1016/S0896-6273(00)80291-3
) / Neuron by G Thinakaran (1996) -
Mercken, M. et al. Characterisation of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing. FEBS Lett. 389, 297–303 (1996).
(
10.1016/0014-5793(96)00608-4
) / FEBS Lett. by M Mercken (1996) -
Kim, T.W., Hallmark, O.G., Pettingell, W., Wasco, W. & Tanzi, R.E. Proteolytic processing of wild-type and mutant forms of presenilin 2. Neurobiol. Aging 17, 155–159 (1996).
(
10.1016/S0197-4580(96)80626-9
) / Neurobiol. Aging by TW Kim (1996) - Podlisny, M.B., Tolan, D.R. & Selkoe, D.J. Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease. Am. J. Pathol. 138, 1423–1435 (1991). / Am. J. Pathol. by MB Podlisny (1991)
-
König, G. et al. Identification and differential expression of a novel alternative splice isoform of the βA4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells. J. Biol. Chem. 267, 10804–10809 (1992).
(
10.1016/S0021-9258(19)50090-4
) / J. Biol. Chem. by G König (1992) -
Wasco, W. et al. Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor. Proc. Natl. Acad. Sci. USA 89, 10758–10762 (1992).
(
10.1073/pnas.89.22.10758
) / Proc. Natl. Acad. Sci. USA by W Wasco (1992) -
High, S. et al. Sec61p is adjacent to nascent type 1 and type II signal-anchor proteins during their membrane insertion. J. Cell Biol. 121, 743–750 (1993).
(
10.1083/jcb.121.4.743
) / J. Cell Biol. by S High (1993) -
Simons, M.T. et al. Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. J. Neurosci. 16, 899–908 (1996).
(
10.1523/JNEUROSCI.16-03-00899.1996
) / J. Neurosci. by MT Simons (1996) -
Hammond, C. & Helenius, A. Quality control in the secretory pathway: Retention of misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus. J. Cell Biol. 126, 41 52 (1994).
(
10.1083/jcb.126.1.41
) / J. Cell Biol. by C Hammond (1994) -
Haass, C. & Selkoe, D.J. Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide. Cell 75, 1039–1042 (1993).
(
10.1016/0092-8674(93)90312-E
) / Cell by C Haass (1993) -
Kuentzel, S.L. et al. The Alzheimer β-amyloid protein precursor/protease nexin-II is cleaved by secretase in a trans-Golgi secretory compartment in human neuroglioma cells. Biochem. J. 295, 367–378 (1993).
(
10.1042/bj2950367
) / Biochem. J. by SL Kuentzel (1993) -
Citron, M. et al. Inhibition of amyloid β-protein production in neural cells by the serine protease inhibitor AEBSF. Neuron 17, 171–179 (1996).
(
10.1016/S0896-6273(00)80290-1
) / Neuron by M Citron (1996) -
Zhong, Z., Quon, D., Higgins, L.S., Higaki, J. & Cordell, B. Increased amyloid production from aberrant beta-amyloid precursor proteins. J. Biol. Chem. 269, 12179–12184 (1994).
(
10.1016/S0021-9258(17)32698-4
) / J. Biol. Chem. by Z Zhong (1994) -
Games, D. et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β–amyloid precursor protein. Nature 373, 523–527 (1995).
(
10.1038/373523a0
) / Nature by D Games (1995) -
Knop, M., Finger, A., Braun, T., Hellmuth, K. & Wolf, D.H., Der1 a novel protein specifically required for endoplasmic reticulum degradation in yeast. EMBO J. 15, 753–763 (1996).
(
10.1002/j.1460-2075.1996.tb00411.x
) / EMBO J. by M Knop (1996) -
Kunkel, T.A., Roberts, J.D. & Zakour, R.A. Rapid and efficient site specific mutagenesis without phenotypic selection. Meth. Enzym. 154, 367–382 (1987).
(
10.1016/0076-6879(87)54085-X
) / Meth. Enzym. by TA Kunkel (1987) -
Dyrks, T. et al. Generation of beta A4 from the amyloid protein precursor and fragments thereof. FEBS Lett. 335, 89–93 (1993).
(
10.1016/0014-5793(93)80446-2
) / FEBS Lett. by T Dyrks (1993)
Dates
Type | When |
---|---|
Created | 21 years ago (Aug. 18, 2004, 9:46 p.m.) |
Deposited | 2 years, 3 months ago (May 18, 2023, 6:11 p.m.) |
Indexed | 11 months, 2 weeks ago (Sept. 8, 2024, 5:38 a.m.) |
Issued | 28 years, 5 months ago (March 1, 1997) |
Published | 28 years, 5 months ago (March 1, 1997) |
Published Print | 28 years, 5 months ago (March 1, 1997) |
@article{Weidemann_1997, title={Formation of stable complexes between two Alzheimer’s disease gene products: Presenilin-2 and β-amyloid precursor protein}, volume={3}, ISSN={1546-170X}, url={http://dx.doi.org/10.1038/nm0397-328}, DOI={10.1038/nm0397-328}, number={3}, journal={Nature Medicine}, publisher={Springer Science and Business Media LLC}, author={Weidemann, A. and Paliga, K. and Dürrwang, U. and Czech, C. and Evin, G. and Masters, C. L. and Beyreuther, K.}, year={1997}, month=mar, pages={328–332} }