Bibliography
Kincaid, E. Z., Che, J. W., York, I., Escobar, H., Reyes-Vargas, E., Delgado, J. C., Welsh, R. M., Karow, M. L., Murphy, A. J., Valenzuela, D. M., Yancopoulos, G. D., & Rock, K. L. (2011). Mice completely lacking immunoproteasomes show major changes in antigen presentation. Nature Immunology, 13(2), 129â135.
Authors
12
- Eleanor Z Kincaid (first)
- Jenny W Che (additional)
- Ian York (additional)
- Hernando Escobar (additional)
- Eduardo Reyes-Vargas (additional)
- Julio C Delgado (additional)
- Raymond M Welsh (additional)
- Margaret L Karow (additional)
- Andrew J Murphy (additional)
- David M Valenzuela (additional)
- George D Yancopoulos (additional)
- Kenneth L Rock (additional)
References
43
Referenced
250
- Rock, K.L. et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class. Mol. Cell 78, 761–771 (1994). / Mol. Cell by KL Rock (1994)
-
Coux, O., Tanaka, K. & Goldberg, A.L. Structure and functions of the 20S and 26S proteasomes. Annu. Rev. Biochem. 65, 801–847 (1996).
(
10.1146/annurev.bi.65.070196.004101
) / Annu. Rev. Biochem. by O Coux (1996) -
Tanaka, K. Role of proteasomes modified by interferon-gamma in antigen processing. J. Leukoc. Biol. 56, 571–575 (1994).
(
10.1002/jlb.56.5.571
) / J. Leukoc. Biol. by K Tanaka (1994) -
Gaczynska, M., Rock, K.L. & Goldberg, A.L. Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature 365, 264–267 (1993).
(
10.1038/365264a0
) / Nature by M Gaczynska (1993) -
Driscoll, J., Brown, M.G., Finley, D. & Monaco, J.J. MHC-linked LMP gene products specifically alter peptidase activities of the proteasome. Nature 365, 262–264 (1993).
(
10.1038/365262a0
) / Nature by J Driscoll (1993) -
Aki, M. et al. Interferon-gamma induces different subunit organizations and functional diversity of proteasomes. J. Biochem. 115, 257–269 (1994).
(
10.1093/oxfordjournals.jbchem.a124327
) / J. Biochem. by M Aki (1994) -
Rammensee, H.G., Falk, K. & Rötzschke, O. Peptides naturally presented by MHC class I molecules. Annu. Rev. Immunol. 11, 213–244 (1993).
(
10.1146/annurev.iy.11.040193.001241
) / Annu. Rev. Immunol. by HG Rammensee (1993) -
Fehling, H.J. et al. MHC class I expression in mice lacking the proteasome subunit LMP-7. Science 265, 1234–1237 (1994).
(
10.1126/science.8066463
) / Science by HJ Fehling (1994) -
Van Kaer, L. et al. Altered peptidase and viral-specific T cell response in LMP2 mutant mice. Immunity 1, 533–541 (1994).
(
10.1016/1074-7613(94)90043-4
) / Immunity by L Van Kaer (1994) -
Chen, W., Norbury, C.C., Cho, Y., Yewdell, J.W. & Bennink, J.R. Immunoproteasomes shape immunodominance hierarchies of antiviral CD8+ T cells at the levels of T cell repertoire and presentation of viral antigens. J. Exp. Med. 193, 1319–1326 (2001).
(
10.1084/jem.193.11.1319
) / J. Exp. Med. by W Chen (2001) -
Nussbaum, A.K., Rodriguez-Carreno, M.P., Benning, N., Botten, J. & Whitton, J.L. Immunoproteasome-deficient mice mount largely normal CD8+ T cell responses to lymphocytic choriomeningitis virus infection and DNA vaccination. J. Immunol. 175, 1153–1160 (2005).
(
10.4049/jimmunol.175.2.1153
) / J. Immunol. by AK Nussbaum (2005) -
Osterloh, P. et al. Proteasomes shape the repertoire of T cells participating in antigen-specific immune responses. Proc. Natl. Acad. Sci. USA 103, 5042–5047 (2006).
(
10.1073/pnas.0509256103
) / Proc. Natl. Acad. Sci. USA by P Osterloh (2006) -
Palmowski, M.J. et al. Role of immunoproteasomes in cross-presentation. J. Immunol. 177, 983–990 (2006).
(
10.4049/jimmunol.177.2.983
) / J. Immunol. by MJ Palmowski (2006) -
Pang, K.C. et al. Immunoproteasome subunit deficiencies impact differentially on two immunodominant influenza virus-specific CD8+ T cell responses. J. Immunol. 177, 7680–7688 (2006).
(
10.4049/jimmunol.177.11.7680
) / J. Immunol. by KC Pang (2006) -
Deol, P., Zaiss, D.M.W., Monaco, J.J. & Sijts, A.J.A.M. Rates of processing determine the immunogenicity of immunoproteasome-generated epitopes. J. Immunol. 178, 7557–7562 (2007).
(
10.4049/jimmunol.178.12.7557
) / J. Immunol. by P Deol (2007) -
Basler, M., Moebius, J., Elenich, L., Groettrup, M. & Monaco, J.J. An altered T cell repertoire in MECL-1-deficient mice. J. Immunol. 176, 6665–6672 (2006).
(
10.4049/jimmunol.176.11.6665
) / J. Immunol. by M Basler (2006) -
Hensley, S.E. et al. Unexpected role for the immunoproteasome subunit LMP2 in antiviral humoral and innate immune responses. J. Immunol. 184, 4115–4122 (2010).
(
10.4049/jimmunol.0903003
) / J. Immunol. by SE Hensley (2010) -
Van Kaer, L. Accessory proteins that control the assembly of MHC molecules with peptides. Immunol. Res. 23, 205–214 (2001).
(
10.1385/IR:23:2-3:205
) / Immunol. Res. by L Van Kaer (2001) -
Macagno, A., Kuehn, L., de Giuli, R. & Groettrup, M. Pronounced up-regulation of the PA28α/β proteasome regulator but little increase in the steady-state content of immunoproteasome during dendritic cell maturation. Eur. J. Immunol. 31, 3271–3280 (2001).
(
10.1002/1521-4141(200111)31:11<3271::AID-IMMU3271>3.0.CO;2-2
) / Eur. J. Immunol. by A Macagno (2001) -
Nil, A., Firat, E., Sobek, V., Eichmann, K. & Niedermann, G. Expression of housekeeping and immunoproteasome subunit genes is differentially regulated in positively and negatively selecting thymic stroma subsets. Eur. J. Immunol. 34, 2681–2689 (2004).
(
10.1002/eji.200425032
) / Eur. J. Immunol. by A Nil (2004) -
Kisielow, P., Blüthmann, H., Staerz, U.D., Steinmetz, M. & von Boehmer, H. Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes. Nature 333, 742–746 (1988).
(
10.1038/333742a0
) / Nature by P Kisielow (1988) -
Markiewicz, M.A. et al. Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules. Proc. Natl. Acad. Sci. USA 95, 3065–3070 (1998).
(
10.1073/pnas.95.6.3065
) / Proc. Natl. Acad. Sci. USA by MA Markiewicz (1998) -
Sanderson, S. & Shastri, N. LacZ inducible, antigen/MHC-specific T cell hybrids. Int. Immunol. 6, 369–376 (1994).
(
10.1093/intimm/6.3.369
) / Int. Immunol. by S Sanderson (1994) -
Greenfield, A. et al. An H-YDb epitope is encoded by a novel mouse Y chromosome gene. Nat. Genet. 14, 474–478 (1996).
(
10.1038/ng1296-474
) / Nat. Genet. by A Greenfield (1996) -
Deckhut, A.M. et al. Prominent usage of V beta 8.3 T cells in the H-2Db-restricted response to an influenza A virus nucleoprotein epitope. J. Immunol. 151, 2658–2666 (1993).
(
10.4049/jimmunol.151.5.2658
) / J. Immunol. by AM Deckhut (1993) -
Rock, K.L., Rothstein, L. & Gamble, S. Generation of class I MHC-restricted T-T hybridomas. J. Immunol. 145, 804–811 (1990).
(
10.4049/jimmunol.145.3.804
) / J. Immunol. by KL Rock (1990) -
Gairin, J.E., Mazarguil, H., Hudrisier, D. & Oldstone, M.B. Optimal lymphocytic choriomeningitis virus sequences restricted by H-2Db major histocompatibility complex class I molecules and presented to cytotoxic T lymphocytes. J. Virol. 69, 2297–2305 (1995).
(
10.1128/jvi.69.4.2297-2305.1995
) / J. Virol. by JE Gairin (1995) -
Basler, M., Youhnovski, N., Van Den Broek, M., Przybylski, M. & Groettrup, M. Immunoproteasomes down-regulate presentation of a subdominant T cell epitope from lymphocytic choriomeningitis virus. J. Immunol. 173, 3925–3934 (2004).
(
10.4049/jimmunol.173.6.3925
) / J. Immunol. by M Basler (2004) -
Stohwasser, R., Standera, S., Peters, I., Kloetzel, P.M. & Groettrup, M. Molecular cloning of the mouse proteasome subunits MC14 and MECL-1: reciprocally regulated tissue expression of interferon-gamma-modulated proteasome subunits. Eur. J. Immunol. 27, 1182–1187 (1997).
(
10.1002/eji.1830270520
) / Eur. J. Immunol. by R Stohwasser (1997) -
Blanchard, N. et al. Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells. J. Immunol. 184, 3033–3042 (2010).
(
10.4049/jimmunol.0903712
) / J. Immunol. by N Blanchard (2010) -
Welsh, R.M. Jr., Lampert, P.W., Burner, P.A. & Oldstone, M.B. Antibody-complement interactions with purified lymphocytic choriomeningitis virus. Virology 73, 59–71 (1976).
(
10.1016/0042-6822(76)90060-X
) / Virology by RM Welsh Jr. (1976) -
Clipstone, N.A. & Crabtree, G.R. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 357, 695–697 (1992).
(
10.1038/357695a0
) / Nature by NA Clipstone (1992) -
Levkau, B. et al. xIAP induces cell-cycle arrest and activates nuclear factor-kappaB: new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells. Circ. Res. 88, 282–290 (2001).
(
10.1161/01.RES.88.3.282
) / Circ. Res. by B Levkau (2001) -
Gillis, S. & Smith, K.A. Long term culture of tumour-specific cytotoxic T cells. Nature 268, 154–156 (1977).
(
10.1038/268154a0
) / Nature by S Gillis (1977) -
Sigal, L.J. & Rock, K.L. Bone marrow-derived antigen-presenting cells are required for the generation of cytotoxic T lymphocyte responses to viruses and use transporter associated with antigen presentation (TAP)-dependent and -independent pathways of antigen presentation. J. Exp. Med. 192, 1143–1150 (2000).
(
10.1084/jem.192.8.1143
) / J. Exp. Med. by LJ Sigal (2000) -
Oh, S., McCaffery, J.M. & Eichelberger, M.C. Dose-dependent changes in influenza virus-infected dendritic cells result in increased allogeneic T-cell proliferation at low, but not high, doses of virus. J. Virol. 74, 5460–5469 (2000).
(
10.1128/JVI.74.12.5460-5469.2000
) / J. Virol. by S Oh (2000) -
Hilton, C.J., Dahl, A.M. & Rock, K.L. Anti-peptide antibody blocks peptide binding to MHC class I molecules in the endoplasmic reticulum. J. Immunol. 166, 3952–3956 (2001).
(
10.4049/jimmunol.166.6.3952
) / J. Immunol. by CJ Hilton (2001) -
Brehm, M.A. et al. T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens. Nat. Immunol. 3, 627–634 (2002).
(
10.1038/ni806
) / Nat. Immunol. by MA Brehm (2002) -
Liu, F. & Whitton, J.L. Cutting edge: re-evaluating the in vivo cytokine responses of CD8+ T cells during primary and secondary viral infections. J. Immunol. 174, 5936–5940 (2005).
(
10.4049/jimmunol.174.10.5936
) / J. Immunol. by F Liu (2005) -
Priyadharshini, B., Welsh, R.M., Greiner, D.L., Gerstein, R.M. & Brehm, M.A. Maturation-dependent licensing of naive T cells for rapid TNF production. PLoS ONE 5, e15038 (2010).
(
10.1371/journal.pone.0015038
) / PLoS ONE by B Priyadharshini (2010) -
Delgado, J.C., Escobar, H., Crockett, D.K., Reyes-Vargas, E. & Jensen, P.E. Identification of naturally processed ligands in the C57BL/6 mouse using large-scale mass spectrometric peptide sequencing and bioinformatics prediction. Immunogenetics 61, 241–246 (2009).
(
10.1007/s00251-009-0360-4
) / Immunogenetics by JC Delgado (2009) -
Escobar, H., Reyes-Vargas, E., Jensen, P.E., Delgado, J.C. & Crockett, D.K. Utility of characteristic QTOF MS/MS fragmentation for MHC class I peptides. J. Proteome Res. 10, 2494–2507 (2011).
(
10.1021/pr101272k
) / J. Proteome Res. by H Escobar (2011) -
Smith, M.H., Parker, J.M., Hodges, R.S. & Barber, B.H. The preparation and characterization of anti-peptide heteroantisera recognizing subregions of the intracytoplasmic domain of class I H-2 antigens. Mol. Immunol. 23, 1077–1092 (1986).
(
10.1016/0161-5890(86)90006-4
) / Mol. Immunol. by MH Smith (1986)
Dates
Type | When |
---|---|
Created | 13 years, 8 months ago (Dec. 25, 2011, 2:29 p.m.) |
Deposited | 4 months, 3 weeks ago (April 11, 2025, 7:30 a.m.) |
Indexed | 3 days ago (Aug. 31, 2025, 6:04 a.m.) |
Issued | 13 years, 8 months ago (Dec. 25, 2011) |
Published | 13 years, 8 months ago (Dec. 25, 2011) |
Published Online | 13 years, 8 months ago (Dec. 25, 2011) |
Published Print | 13 years, 7 months ago (Feb. 1, 2012) |
@article{Kincaid_2011, title={Mice completely lacking immunoproteasomes show major changes in antigen presentation}, volume={13}, ISSN={1529-2916}, url={http://dx.doi.org/10.1038/ni.2203}, DOI={10.1038/ni.2203}, number={2}, journal={Nature Immunology}, publisher={Springer Science and Business Media LLC}, author={Kincaid, Eleanor Z and Che, Jenny W and York, Ian and Escobar, Hernando and Reyes-Vargas, Eduardo and Delgado, Julio C and Welsh, Raymond M and Karow, Margaret L and Murphy, Andrew J and Valenzuela, David M and Yancopoulos, George D and Rock, Kenneth L}, year={2011}, month=dec, pages={129–135} }