Bibliography
Bürckstümmer, T., Baumann, C., Blüml, S., Dixit, E., Dürnberger, G., Jahn, H., Planyavsky, M., Bilban, M., Colinge, J., Bennett, K. L., & Superti-Furga, G. (2009). An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nature Immunology, 10(3), 266â272.
Authors
11
- Tilmann Bürckstümmer (first)
- Christoph Baumann (additional)
- Stephan Blüml (additional)
- Evelyn Dixit (additional)
- Gerhard Dürnberger (additional)
- Hannah Jahn (additional)
- Melanie Planyavsky (additional)
- Martin Bilban (additional)
- Jacques Colinge (additional)
- Keiryn L Bennett (additional)
- Giulio Superti-Furga (additional)
References
28
Referenced
894
-
Pichlmair, A. & Reis, E.S.C. Innate recognition of viruses. Immunity 27, 370–383 (2007).
(
10.1016/j.immuni.2007.08.012
) / Immunity by A Pichlmair (2007) - Akira, S. TLR signaling. Curr. Top. Microbiol. Immunol. 311, 1–16 (2006). / Curr. Top. Microbiol. Immunol. by S Akira (2006)
-
Takaoka, A. et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448, 501–508 (2007).
(
10.1038/nature06013
) / Nature by A Takaoka (2007) -
Wang, Z. et al. Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules. Proc. Natl. Acad. Sci. USA 105, 5477–5482 (2008).
(
10.1073/pnas.0801295105
) / Proc. Natl. Acad. Sci. USA by Z Wang (2008) -
Ishii, K.J. et al. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature 451, 725–729 (2008).
(
10.1038/nature06537
) / Nature by KJ Ishii (2008) -
Ishii, K.J. et al. A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nat. Immunol. 7, 40–48 (2006).
(
10.1038/ni1282
) / Nat. Immunol. by KJ Ishii (2006) -
Stetson, D.B. & Medzhitov, R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity 24, 93–103 (2006).
(
10.1016/j.immuni.2005.12.003
) / Immunity by DB Stetson (2006) -
Petrilli, V., Dostert, C., Muruve, D.A. & Tschopp, J. The inflammasome: a danger sensing complex triggering innate immunity. Curr. Opin. Immunol. 19, 615–622 (2007).
(
10.1016/j.coi.2007.09.002
) / Curr. Opin. Immunol. by V Petrilli (2007) -
Muruve, D.A. et al. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452, 103–107 (2008).
(
10.1038/nature06664
) / Nature by DA Muruve (2008) - Shinozuka, K., Morita, T. & Sawai, H. Synthesis and nuclease susceptibility of alpha-oligodeoxyribonucleotide phosphorothioate. Nucleic Acids Symp. Ser. 25, 101–102 (1991). / Nucleic Acids Symp. Ser. by K Shinozuka (1991)
-
Mazur, D.J. & Perrino, F.W. Excision of 3′ termini by the Trex1 and TREX2 3′→5′ exonucleases. Characterization of the recombinant proteins. J. Biol. Chem. 276, 17022–17029 (2001).
(
10.1074/jbc.M100623200
) / J. Biol. Chem. by DJ Mazur (2001) -
Morita, M. et al. Gene-targeted mice lacking the Trex1 (DNase III) 3′→5′ DNA exonuclease develop inflammatory myocarditis. Mol. Cell. Biol. 24, 6719–6727 (2004).
(
10.1128/MCB.24.15.6719-6727.2004
) / Mol. Cell. Biol. by M Morita (2004) -
Stetson, D.B., Ko, J.S., Heidmann, T. & Medzhitov, R. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134, 587–598 (2008).
(
10.1016/j.cell.2008.06.032
) / Cell by DB Stetson (2008) -
Choubey, D. & Panchanathan, R. Interferon-inducible Ifi200-family genes in systemic lupus erythematosus. Immunol. Lett. 119, 32–41 (2008).
(
10.1016/j.imlet.2008.06.001
) / Immunol. Lett. by D Choubey (2008) -
Caposio, P. et al. A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells. J. Biol. Chem. 282, 33515–33529 (2007).
(
10.1074/jbc.M701846200
) / J. Biol. Chem. by P Caposio (2007) -
Moriya, M. et al. Role of charged and hydrophobic residues in the oligomerization of the PYRIN domain of ASC. Biochemistry 44, 575–583 (2005).
(
10.1021/bi048374i
) / Biochemistry by M Moriya (2005) -
Albrecht, M., Choubey, D. & Lengauer, T. The HIN domain of IFI-200 proteins consists of two OB folds. Biochem. Biophys. Res. Commun. 327, 679–687 (2005).
(
10.1016/j.bbrc.2004.12.056
) / Biochem. Biophys. Res. Commun. by M Albrecht (2005) -
Masumoto, J., Taniguchi, S. & Sagara, J. Pyrin N-terminal homology domain- and caspase recruitment domain-dependent oligomerization of ASC. Biochem. Biophys. Res. Commun. 280, 652–655 (2001).
(
10.1006/bbrc.2000.4190
) / Biochem. Biophys. Res. Commun. by J Masumoto (2001) -
Natarajan, A., Ghose, R. & Hill, J.M. Structure and dynamics of ASC2, a pyrin domain-only protein that regulates inflammatory signaling. J. Biol. Chem. 281, 31863–31875 (2006).
(
10.1074/jbc.M605458200
) / J. Biol. Chem. by A Natarajan (2006) -
Yu, H.B. & Finlay, B.B. The caspase-1 inflammasome: a pilot of innate immune responses. Cell Host Microbe 4, 198–208 (2008).
(
10.1016/j.chom.2008.08.007
) / Cell Host Microbe by HB Yu (2008) -
Hornung, V. et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat. Immunol. 9, 847–856 (2008).
(
10.1038/ni.1631
) / Nat. Immunol. by V Hornung (2008) -
Kanneganti, T.D., Lamkanfi, M. & Nunez, G. Intracellular NOD-like receptors in host defense and disease. Immunity 27, 549–559 (2007).
(
10.1016/j.immuni.2007.10.002
) / Immunity by TD Kanneganti (2007) -
Johnston, J.B. et al. A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection. Immunity 23, 587–598 (2005).
(
10.1016/j.immuni.2005.10.003
) / Immunity by JB Johnston (2005) -
Dorfleutner, A. et al. A Shope Fibroma virus PYRIN-only protein modulates the host immune response. Virus Genes 35, 685–694 (2007).
(
10.1007/s11262-007-0141-9
) / Virus Genes by A Dorfleutner (2007) -
Baechler, E.C. et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc. Natl. Acad. Sci. USA 100, 2610–2615 (2003).
(
10.1073/pnas.0337679100
) / Proc. Natl. Acad. Sci. USA by EC Baechler (2003) -
Woerner, S.M. et al. The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers. Genes Chromosom. Cancer 46, 1080–1089 (2007).
(
10.1002/gcc.20493
) / Genes Chromosom. Cancer by SM Woerner (2007) -
Burckstummer, T. et al. An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells. Nat. Methods 3, 1013–1019 (2006).
(
10.1038/nmeth968
) / Nat. Methods by T Burckstummer (2006) -
Irizarry, R.A. et al. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res. 31, e15 (2003).
(
10.1093/nar/gng015
) / Nucleic Acids Research by R. A. Irizarry (2003)
Dates
Type | When |
---|---|
Created | 16 years, 7 months ago (Jan. 21, 2009, 2:01 p.m.) |
Deposited | 3 years, 1 month ago (July 29, 2022, 3:50 p.m.) |
Indexed | 1 day, 18 hours ago (Aug. 31, 2025, 7:18 p.m.) |
Issued | 16 years, 7 months ago (Jan. 21, 2009) |
Published | 16 years, 7 months ago (Jan. 21, 2009) |
Published Online | 16 years, 7 months ago (Jan. 21, 2009) |
Published Print | 16 years, 6 months ago (March 1, 2009) |
@article{B_rckst_mmer_2009, title={An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome}, volume={10}, ISSN={1529-2916}, url={http://dx.doi.org/10.1038/ni.1702}, DOI={10.1038/ni.1702}, number={3}, journal={Nature Immunology}, publisher={Springer Science and Business Media LLC}, author={Bürckstümmer, Tilmann and Baumann, Christoph and Blüml, Stephan and Dixit, Evelyn and Dürnberger, Gerhard and Jahn, Hannah and Planyavsky, Melanie and Bilban, Martin and Colinge, Jacques and Bennett, Keiryn L and Superti-Furga, Giulio}, year={2009}, month=jan, pages={266–272} }