DOI: 10.1038/ng959. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

10.1038/ng959

Crossref journal-article

Springer Science and Business Media LLC

Nature Genetics (297)

Bibliography

Kawaguchi, Y., Cooper, B., Gannon, M., Ray, M., MacDonald, R. J., & Wright, C. V. E. (2002). The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nature Genetics, 32(1), 128â134.

Authors 6

Yoshiya Kawaguchi (first)
Bonnie Cooper (additional)
Maureen Gannon (additional)
Michael Ray (additional)
Raymond J. MacDonald (additional)
Christopher V.E. Wright (additional)

References 26 Referenced 855

Lumelsky, N. et al. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 292, 1389–1394 (2001). (10.1126/science.1058866) / Science by N Lumelsky (2001)
Edlund, H. Developmental biology of the pancreas. Diabetes 50 (Suppl 1), S5–9 (2001). (10.2337/diabetes.50.2007.S5) / Diabetes by H Edlund (2001)
Kim, S.K. & Hebrok, M. Intercellular signals regulating pancreas development and function. Genes. Dev. 15, 111–127 (2001). (10.1101/gad.859401) / Genes. Dev. by SK Kim (2001)
Krapp, A. et al. The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J. 15, 4317–4329 (1996). (10.1002/j.1460-2075.1996.tb00806.x) / EMBO J. by A Krapp (1996)
Adell, T. et al. Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells. Cell. Growth. Differ. 11, 137–147 (2000). / Cell. Growth. Differ. by T Adell (2000)
Rose, S.D., Swift, G.H., Peyton, M.J., Hammer, R.E. & MacDonald, R.J. The role of PTF1-p48 in pancreatic acinar gene expression. J. Biol. Chem. 276, 44018–44026 (2001). (10.1074/jbc.M106264200) / J. Biol. Chem. by SD Rose (2001)
Krapp, A. et al. The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes. Dev. 12, 3752–3763 (1998). (10.1101/gad.12.23.3752) / Genes. Dev. by A Krapp (1998)
Obata, J. et al. p48 subunit of mouse PTF1 binds to RBP-Jκ/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos. Genes. Cells 6, 345–360 (2001). (10.1046/j.1365-2443.2001.00422.x) / Genes. Cells by J Obata (2001)
Li, H. & Edlund, H. Persistent expression of Hlxb9 in the pancreatic epithelium impairs pancreatic development. Dev. Biol. 240, 247–253 (2001). (10.1006/dbio.2001.0440) / Dev. Biol. by H Li (2001)
Herrera, P.L. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 127, 2317–2322 (2000). (10.1242/dev.127.11.2317) / Development by PL Herrera (2000)
Gu, G., Dubauskaite, J. & Melton, D. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 129, 2447–2457 (2000). (10.1242/dev.129.10.2447) / Development by G Gu (2000)
Gannon, M., Shiota, C., Postic, C., Wright, C.V. & Magnuson, M. Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas. Genesis 26, 139–142 (2000). (10.1002/(SICI)1526-968X(200002)26:2<139::AID-GENE12>3.0.CO;2-7) / Genesis by M Gannon (2000)
Soriano, P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70–71 (1999). (10.1038/5007) / Nat. Genet. by P Soriano (1999)
Jonsson, J., Carlsson, L., Edlund, T. & Edlund, H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371, 606–609 (1994). (10.1038/371606a0) / Nature by J Jonsson (1994)
Offield, M.F. et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 122, 983–995 (1996). (10.1242/dev.122.3.983) / Development by MF Offield (1996)
Ahlgren, U., Jonsson, J., Jonsson, L., Simu, K. & Edlund, H. Beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes. Dev. 12, 1763–1768 (1998). (10.1101/gad.12.12.1763) / Genes. Dev. by U Ahlgren (1998)
Zaret, K.S. Hepatocyte differentiation: from the endoderm and beyond. Curr. Opin. Genet. Dev. 11, 568–574 (2001). (10.1016/S0959-437X(00)00234-3) / Curr. Opin. Genet. Dev. by KS Zaret (2001)
Matsumoto, K., Yoshitomi, H., Rossant, J. & Zaret, K.S. Liver organogenesis promoted by endothelial cells prior to vascular function. Science 294, 559–563 (2001). (10.1126/science.1063889) / Science by K Matsumoto (2001)
Lammert, E., Cleaver, O. & Melton, D. Induction of pancreatic differentiation by signals from blood vessels. Science 294, 564–567 (2001). (10.1126/science.1064344) / Science by E Lammert (2001)
Gannon, M., Herrera, P.L. & Wright, C.V. Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter. Genesis 26, 143–144 (2000). (10.1002/(SICI)1526-968X(200002)26:2<143::AID-GENE13>3.0.CO;2-L) / Genesis by M Gannon (2000)
Hogan, B.L.M., Beddington, R., Constantin, F. & Lacy, E. Manipulating the Mouse Embryo. Cold Spring Harbor Lab. Press, Plainview, NY. (1994). / Manipulating the Mouse Embryo by BLM Hogan (1994)
Lakso, M. et al. Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc. Natl Acad Sci. USA 93, 5860–5865 (1996). (10.1073/pnas.93.12.5860) / Proc. Natl Acad Sci. USA by M Lakso (1996)
Sasaki, H. & Hogan, B.L. Enhancer analysis of the mouse HNF-3β gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements. Genes. Cells 1, 59–72 (1996). (10.1046/j.1365-2443.1996.04004.x) / Genes. Cells by H Sasaki (1996)
Wu, K.L. et al. Hepatocyte nuclear factor 3β is involved in pancreatic beta-cell–specific transcription of the pdx-1 gene. Mol. Cell. Biol. 17, 6002–6013 (1997). (10.1128/MCB.17.10.6002) / Mol. Cell. Biol. by KL Wu (1997)
Peshavaria, M. et al. XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Mol. Endocrinol. 8, 806–816 (1994). / Mol. Endocrinol. by M Peshavaria (1994)
MacDonald, R.J., Przybyla, A.E. & Rutter, W.J. Isolation and in vitro translation of the messenger RNA coding for pancreatic amylase. J. Biol. Chem. 252, 5522–5528 (1977). (10.1016/S0021-9258(19)63382-X) / J. Biol. Chem. by RJ MacDonald (1977)

Dates

Type	When
Created	23 years ago (Aug. 30, 2002, 1:48 p.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 6:18 p.m.)
Indexed	3 weeks, 2 days ago (Aug. 12, 2025, 5:54 p.m.)
Issued	23 years ago (Aug. 19, 2002)
Published	23 years ago (Aug. 19, 2002)
Published Online	23 years ago (Aug. 19, 2002)
Published Print	23 years ago (Sept. 1, 2002)

Funders 0

None

BibTeX

@article{Kawaguchi_2002, title={The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors}, volume={32}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng959}, DOI={10.1038/ng959}, number={1}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Kawaguchi, Yoshiya and Cooper, Bonnie and Gannon, Maureen and Ray, Michael and MacDonald, Raymond J. and Wright, Christopher V.E.}, year={2002}, month=aug, pages={128–134} }

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