Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer
10.1038/ng958
Crossref journal-article
Springer Science and Business Media LLC
Nature Genetics (297)
Bibliography

Spring, K., Ahangari, F., Scott, S. P., Waring, P., Purdie, D. M., Chen, P. C., Hourigan, K., Ramsay, J., McKinnon, P. J., Swift, M., & Lavin, M. F. (2002). Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer. Nature Genetics, 32(1), 185–190.

Authors 11
  1. Kevin Spring (first)
  2. Farida Ahangari (additional)
  3. Shaun P. Scott (additional)
  4. Paul Waring (additional)
  5. David M. Purdie (additional)
  6. Philip C. Chen (additional)
  7. Kevin Hourigan (additional)
  8. Jonathan Ramsay (additional)
  9. Peter J. McKinnon (additional)
  10. Michael Swift (additional)
  11. Martin F. Lavin (additional)
References 30 Referenced 121
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  6. Athma, P., Rappaport, R. & Swift, M. Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer. Cancer Genet. Cytogenet. 92, 130–134 (1996). (10.1016/S0165-4608(96)00328-7) / Cancer Genet. Cytogenet. by P Athma (1996)
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  13. Elson, A. et al. Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc. Natl Acad. Sci. USA 93, 13084–13089 (1996). (10.1073/pnas.93.23.13084) / Proc. Natl Acad. Sci. USA by A Elson (1996)
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  15. Savitsky, K. et al. A single ataxia-telangiectasia gene with a product similar to PI-3 kinase. Science 268, 1749–1753 (1995). (10.1126/science.7792600) / Science by K Savitsky (1995)
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  28. Scott S.P. et al. Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer. Proc. Natl Acad. Sci. USA 99, 925–930 (2002). (10.1073/pnas.012329699) / Proc. Natl Acad. Sci. USA by SP Scott (2002)
  29. Barlow, C., Eckhaus, M.A., Schaffer, A.A. & Wynshaw-Boris, A. Atm haploinsufficiency results in increased sensitivity to sublethal doses of ionizing radiation in mice. Nature Genet. 21, 359–360 (1999). (10.1038/7684) / Nature Genet. by C Barlow (1999)
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Dates
Type When
Created 23 years ago (Aug. 30, 2002, 1:48 p.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 6:18 p.m.)
Indexed 2 months ago (July 1, 2025, 9:48 a.m.)
Issued 23 years ago (Aug. 26, 2002)
Published 23 years ago (Aug. 26, 2002)
Published Online 23 years ago (Aug. 26, 2002)
Published Print 23 years ago (Sept. 1, 2002)
Funders 0

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@article{Spring_2002, title={Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer}, volume={32}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng958}, DOI={10.1038/ng958}, number={1}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Spring, Kevin and Ahangari, Farida and Scott, Shaun P. and Waring, Paul and Purdie, David M. and Chen, Philip C. and Hourigan, Kevin and Ramsay, Jonathan and McKinnon, Peter J. and Swift, Michael and Lavin, Martin F.}, year={2002}, month=aug, pages={185–190} }