DOI: 10.1038/ng761. Population genetic structure of variable drug response

Population genetic structure of variable drug response

10.1038/ng761

Crossref journal-article

Springer Science and Business Media LLC

Nature Genetics (297)

Bibliography

Wilson, J. F., Weale, M. E., Smith, A. C., Gratrix, F., Fletcher, B., Thomas, M. G., Bradman, N., & Goldstein, D. B. (2001). Population genetic structure of variable drug response. Nature Genetics, 29(3), 265â269.

Authors 8

James F. Wilson (first)
Michael E. Weale (additional)
Alice C. Smith (additional)
Fiona Gratrix (additional)
Benjamin Fletcher (additional)
Mark G. Thomas (additional)
Neil Bradman (additional)
David B. Goldstein (additional)

References 21 Referenced 343

Weber, W.W. Pharmacogenetics (Oxford University Press, Oxford, 1997). / Pharmacogenetics by WW Weber (1997)
Evans, W.E. & Relling, M.V. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 487–491 (1999). (10.1126/science.286.5439.487) / Science by WE Evans (1999)
Gough, A.C. et al. Identification of the primary gene defect at the cytochrome P450 CYP2D locus. Nature 347, 773–776 (1990). (10.1038/347773a0) / Nature by AC Gough (1990)
Kagimoto, M., Heim, M., Kagimoto, K., Zeugin, T. & Meyer, U.A. Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes. J. Biol. Chem. 265, 17209–17214 (1990). (10.1016/S0021-9258(17)44890-3) / J. Biol. Chem. by M Kagimoto (1990)
Blum, M., Demierre, A., Grant, D.M., Heim, M. & Meyer, U.A. Molecular mechanism of slow acetylation of drugs and carcinogens in humans. Proc. Natl Acad. Sci. USA 88, 5237–5241 (1991). (10.1073/pnas.88.12.5237) / Proc. Natl Acad. Sci. USA by M Blum (1991)
Bernal, M.L. et al. Ten percent of North Spanish individuals carry duplicated or triplicated CYP2D6 genes associated with ultrarapid metabolism of debrisoquine. Pharmacogenetics 9, 657–660 (1999). (10.1097/00008571-199910000-00013) / Pharmacogenetics by ML Bernal (1999)
Meyer, U.A. & Zanger, U.M. Molecular mechanisms of genetic polymorphisms of drug metabolism. Annu. Rev. Pharmacol. Toxicol. 37, 269–296 (1997). (10.1146/annurev.pharmtox.37.1.269) / Annu. Rev. Pharmacol. Toxicol. by UA Meyer (1997)
International Conference on Harmonisation. Ethnic Factors in the Acceptability of Foreign Clinical Data. (International Conference on Harmonisation, 1998).
Wilson, J.F. & Goldstein, D.B. Consistent long-range linkage disequilibrium generated by admixture in a Bantu–Semitic hybrid population. Am. J. Hum. Genet. 67, 926–935 (2000). (10.1086/303083) / Am. J. Hum. Genet. by JF Wilson (2000)
Pritchard, J.K., Stephens, M. & Donnelly, P. Inference of population structure using multilocus genotype data. Genetics 155, 945–959 (2000). (10.1093/genetics/155.2.945) / Genetics by JK Pritchard (2000)
Seielstad, M.T., Minch, E. & Cavalli-Sforza, L.L. Genetic evidence for a higher female migration rate in humans. Nature Genet. 20, 278–280 (1998). (10.1038/3088) / Nature Genet. by MT Seielstad (1998)
Kohlmeier, L., DeMarini, D. & Piegorsch, W. Gene-nutrient interactions in nutritional epidemiology. in Design Concepts in Nutritional Epidemiology (eds. Margetts, B. & Nelson, M.) 312–337 (Oxford University Press, Oxford, 1997). (10.1093/acprof:oso/9780192627391.003.0011) / Design Concepts in Nutritional Epidemiology by L Kohlmeier (1997)
Raymond, M. & Rousset, F. An exact test for population differentiation. Evolution 49, 1280–1283 (1995). (10.1111/j.1558-5646.1995.tb04456.x) / Evolution by M Raymond (1995)
Krajinovic, M., Labuda, D., Richer, C., Karimi, S. & Sinnett, D. Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms. Blood 93, 1496–1501 (1999). (10.1182/blood.V93.5.1496) / Blood by M Krajinovic (1999)
Gaedigk, A. et al. NAD(P)H:quinone oxidoreductase: polymorphisms and allele frequencies in Caucasian, Chinese and Canadian Native Indian and Inuit populations. Pharmacogenetics 8, 305–313 (1998). (10.1097/00008571-199808000-00004) / Pharmacogenetics by A Gaedigk (1998)
Goldstein, J.A. & Blaisdell, J. Genetic tests which identify the principal defects in CYP2C19 responsible for the polymorphism in mephenytoin metabolism. Methods Enzymol. 272, 210–218 (1996). (10.1016/S0076-6879(96)72025-6) / Methods Enzymol. by JA Goldstein (1996)
Gaedigk, A. et al. Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data. Pharmacogenetics 9, 669–682 (1999). (10.1097/01213011-199912000-00002) / Pharmacogenetics by A Gaedigk (1999)
Basile, V.S. et al. A functional polymorphism of the cytochrome P450 1A2 (CYP1A2) gene: association with tardive dyskinesia in schizophrenia. Mol. Psychiatry 5, 410–417 (2000). (10.1038/sj.mp.4000736) / Mol. Psychiatry by VS Basile (2000)
Ferguson, R.J. et al. A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin. J. Pharmacol. Exp. Ther. 284, 356–361 (1998). / J. Pharmacol. Exp. Ther. by RJ Ferguson (1998)
Daly, A.K. et al. Nomenclature for human CYP2D6 alleles. Pharmacogenetics 6, 193–201 (1996). (10.1097/00008571-199606000-00001) / Pharmacogenetics by AK Daly (1996)
Sachse, C., Brockmoller, J., Bauer, S. & Roots, I. Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine. Br. J. Clin. Pharmacol. 47, 445–449 (1999). (10.1046/j.1365-2125.1999.00898.x) / Br. J. Clin. Pharmacol. by C Sachse (1999)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:31 a.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 6:15 p.m.)
Indexed	5 days, 12 hours ago (Aug. 31, 2025, 7:27 p.m.)
Issued	23 years, 10 months ago (Oct. 29, 2001)
Published	23 years, 10 months ago (Oct. 29, 2001)
Published Online	23 years, 10 months ago (Oct. 29, 2001)
Published Print	23 years, 10 months ago (Nov. 1, 2001)

Funders 0

None

BibTeX

@article{Wilson_2001, title={Population genetic structure of variable drug response}, volume={29}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng761}, DOI={10.1038/ng761}, number={3}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Wilson, James F. and Weale, Michael E. and Smith, Alice C. and Gratrix, Fiona and Fletcher, Benjamin and Thomas, Mark G. and Bradman, Neil and Goldstein, David B.}, year={2001}, month=oct, pages={265–269} }

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