DOI: 10.1038/ng1675. DICER-LIKE 4 is required for RNA interference and produces the 21-nucleotide small interfering RNA component of the plant cell-to-cell silencing signal

DICER-LIKE 4 is required for RNA interference and produces the 21-nucleotide small interfering RNA component of the plant cell-to-cell silencing signal

10.1038/ng1675

Crossref journal-article

Springer Science and Business Media LLC

Nature Genetics (297)

Bibliography

Dunoyer, P., Himber, C., & Voinnet, O. (2005). DICER-LIKE 4 is required for RNA interference and produces the 21-nucleotide small interfering RNA component of the plant cell-to-cell silencing signal. Nature Genetics, 37(12), 1356â1360.

Authors 3

Patrice Dunoyer (first)
Christophe Himber (additional)
Olivier Voinnet (additional)

References 25 Referenced 331

Fire, A. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806–811 (1998). (10.1038/35888) / Nature by A Fire (1998)
Waterhouse, P.M. & Helliwell, C.A. Exploring plant genomes by RNA-induced gene silencing. Nat. Rev. Genet. 4, 29–38 (2003). (10.1038/nrg982) / Nat. Rev. Genet. by PM Waterhouse (2003)
Bernstein, E., Caudy, A.A., Hammond, S.M. & Hannon, G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363–366 (2001). (10.1038/35053110) / Nature by E Bernstein (2001)
Hammond, S.M., Bernstein, E., Beach, D. & Hannon, G. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cell extracts. Nature 404, 293–296 (2000). (10.1038/35005107) / Nature by SM Hammond (2000)
Hamilton, A., Voinnet, O., Chappell, L. & Baulcombe, D.C. Two classes of short interfering RNA in RNA silencing. EMBO J. 21, 4671–4679 (2002). (10.1093/emboj/cdf464) / EMBO J. by A Hamilton (2002)
Mello, C.C. & Conte, D. Jr. Revealing the world of RNA interference. Nature 431, 338–342 (2004). (10.1038/nature02872) / Nature by CC Mello (2004)
Palauqui, J.-C., Elmayan, T., Pollien, J.-M. & Vaucheret, H. Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO J. 16, 4738–4745 (1997). (10.1093/emboj/16.15.4738) / EMBO J. by J-C Palauqui (1997)
Voinnet, O. & Baulcombe, D.C. Systemic signalling in gene silencing. Nature 389, 553 (1997). (10.1038/39215) / Nature by O Voinnet (1997)
Voinnet, O., Vain, P., Angell, S. & Baulcombe, D.C. Systemic spread of sequence-specific transgene RNA degradation is initiated by localised introduction of ectopic promoterless DNA. Cell 95, 177–187 (1998). (10.1016/S0092-8674(00)81749-3) / Cell by O Voinnet (1998)
Winston, W.M., Molodowitch, C. & Hunter, C.P. Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1. Science 295, 2456–2459 (2002). (10.1126/science.1068836) / Science by WM Winston (2002)
Gasciolli, V., Mallory, A.C., Bartel, D.P. & Vaucheret, H. Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs. Curr. Biol. 15, 1494–1500 (2005). (10.1016/j.cub.2005.07.024) / Curr. Biol. by V Gasciolli (2005)
Xie, Z., Allen, E., Wilken, A. & Carrington, J.C. DICER-LIKE4 functions in trans-acting siRNA biogenesis and vegetative phase change in Arabidopsis thaliana. Proc. Natl. Acad. Sci. USA 102, 12984–12989 (2005). (10.1073/pnas.0506426102) / Proc. Natl. Acad. Sci. USA by Z Xie (2005)
Tang, G., Reinhart, B.J., Bartel, D.P. & Zamore, P.D. A biochemical framework for RNA silencing in plants. Genes Dev. 17, 49–63 (2003). (10.1101/gad.1048103) / Genes Dev. by G Tang (2003)
Xie, Z. et al. Genetic and functional diversification of small RNA pathways in plants. PLoS Biol. 2, E104 (2004). (10.1371/journal.pbio.0020104) / PLoS Biol. by Z Xie (2004)
Bartel, B. & Bartel, D.P. MicroRNAs: at the root of plant development? Plant Physiol. 132, 709–717 (2003). (10.1104/pp.103.023630) / Plant Physiol. by B Bartel (2003)
Bartel, D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281–297 (2004). (10.1016/S0092-8674(04)00045-5) / Cell by DP Bartel (2004)
Peragine, A., Yoshikawa, M., Wu, G., Albrecht, H.L. & Poethig, R.S. SGS3 and SGS2/SDE1/RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis. Genes Dev. 18, 2368–2379 (2004). (10.1101/gad.1231804) / Genes Dev. by A Peragine (2004)
Himber, C., Dunoyer, P., Moissiard, G., Ritzenthaler, C. & Voinnet, O. Transitivity-dependent and -independent cell-to-cell movement of RNA silencing. EMBO J. 22, 4523–4533 (2003). (10.1093/emboj/cdg431) / EMBO J. by C Himber (2003)
Schwach, F., Vaistij, F.E., Jones, L. & Baulcombe, D.C. An RNA-dependent RNA polymerase prevents meristem invasion by potato virus X and is required for the activity but not the production of a systemic silencing signal. Plant Physiol. 138, 1842–1852 (2005). (10.1104/pp.105.063537) / Plant Physiol. by F Schwach (2005)
Allen, E., Xie, Z., Gustafson, A.M. & Carrington, J.C. microRNA-directed phasing during trans-acting siRNA biogenesis in plants. Cell 121, 207–221 (2005). (10.1016/j.cell.2005.04.004) / Cell by E Allen (2005)
Carmell, M.A., Xuan, Z., Zhang, M.Q. & Hannon, G.J. The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev. 16, 2733–2742 (2002). (10.1101/gad.1026102) / Genes Dev. by MA Carmell (2002)
Mourrain, P. et al. Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance. Cell 101, 533–542 (2000). (10.1016/S0092-8674(00)80863-6) / Cell by P Mourrain (2000)
Dalmay, T., Hamilton, A.J., Rudd, S., Angell, S. & Baulcombe, D.C. An RNA-dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus. Cell 101, 543–553 (2000). (10.1016/S0092-8674(00)80864-8) / Cell by T Dalmay (2000)
Elbashir, S.M., Lendeckel, W. & Tuschl, T. RNA interference is mediated by 21-and 22-nucleotide RNAs. Genes Dev. 15, 188–200 (2001). (10.1101/gad.862301) / Genes Dev. by SM Elbashir (2001)
Szittya, G., Molnar, A., Silhavy, D., Hornyik, C. & Burgyan, J. Short defective interfering RNAs of tombusviruses are not targeted but trigger post-transcriptional gene silencing against their helper virus. Plant Cell 14, 359–372 (2002). (10.1105/tpc.010366) / Plant Cell by G Szittya (2002)

Dates

Type	When
Created	19 years, 9 months ago (Nov. 6, 2005, 3:27 p.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 6:10 p.m.)
Indexed	1 month, 4 weeks ago (June 26, 2025, 10:07 p.m.)
Issued	19 years, 9 months ago (Nov. 6, 2005)
Published	19 years, 9 months ago (Nov. 6, 2005)
Published Online	19 years, 9 months ago (Nov. 6, 2005)
Published Print	19 years, 8 months ago (Dec. 1, 2005)

Funders 0

None

BibTeX

@article{Dunoyer_2005, title={DICER-LIKE 4 is required for RNA interference and produces the 21-nucleotide small interfering RNA component of the plant cell-to-cell silencing signal}, volume={37}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng1675}, DOI={10.1038/ng1675}, number={12}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Dunoyer, Patrice and Himber, Christophe and Voinnet, Olivier}, year={2005}, month=nov, pages={1356–1360} }

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