Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
10.1038/ng1195-241
Crossref journal-article
Springer Science and Business Media LLC
Nature Genetics (297)
Bibliography

Lander, E., & Kruglyak, L. (1995). Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nature Genetics, 11(3), 241–247.

Authors 2
  1. Eric Lander (first)
  2. Leonid Kruglyak (additional)
References 38 Referenced 3,982
  1. Botstein, D., White, D.L., Skolnick, M. & Davis, R.W. Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am. J. hum. Genet. 32, 314–331 (1980). / Am. J. hum. Genet. by D Botstein (1980)
  2. Baron, M. et al. Genetic linkage between X-chromosome markers and bipolar affective illness. Nature 326, 289–292 (1987). (10.1038/326289a0) / Nature by M Baron (1987)
  3. Egeland, J.A. et al. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature 325, 783–787 (1987). (10.1038/325783a0) / Nature by JA Egeland (1987)
  4. Kelsoe, J.R. et al. Re-evaluation of the linkage relationship between chromosome 11 p loci and the gene for bipolar affective disorder in the Old Order Amish. Nature 342, 238–243 (1989). (10.1038/342238a0) / Nature by JR Kelsoe (1989)
  5. Sherrington, R. et al. Localization of a susceptibility locus for schizophrenia on chromosome 5. Nature 336, 164–167 (1988). (10.1038/336164a0) / Nature by R Sherrington (1988)
  6. Kennedy, J.L. et al. Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigree. Nature 336, 167–170 (1988). (10.1038/336167a0) / Nature by JL Kennedy (1988)
  7. Baron, M. et al. Diminished support for linkage between manic depressive illness and X-chromosome markers in three Israeli pedigrees. Nature Genet. 3, 49–55 (1993). (10.1038/ng0193-49) / Nature Genet. by M Baron (1993)
  8. Lander, E.S. & Botstein, D. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121, 185–199 (1989). (10.1093/genetics/121.1.185) / Genetics by ES Lander (1989)
  9. Feingold, E., Brown, P.O. & Siegmund, D. Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent. Am. J. hum. Genet. 53, 234–251 (1993). / Am. J. hum. Genet. by E Feingold (1993)
  10. Chotai, J. On the lod score method in linkage analysis. Ann. hum. Genet. 48, 359–378 (1984). (10.1111/j.1469-1809.1984.tb00849.x) / Ann. hum. Genet. by J Chotai (1984)
  11. Elston, R.C. Designs for the global search of the human genome by linkage analysis. In Proceedings of the 16th international Biometrics conference 39–51 (Hamilton, New Zealand, 1992). / Proceedings of the 16th international Biometrics conference by RC Elston (1992)
  12. Brown, D.L., Gorin, M.B. & Weeks, D.E. Efficient strategies for genomic searching using the affected-pedigree-member method of linkage analysis. Am. J. hum. Genet. 54, 544–652 (1994). / Am. J. hum. Genet. by DL Brown (1994)
  13. McKusick, V.A. & Edwards, J.H. Unassigned syntenic groups and theoretical considerations. Second international workshop on human gene mapping. Cytogenet Cell Genet. 14, 196–198 (1975). (10.1159/000130344) / Cytogenet Cell Genet. by VA McKusick (1975)
  14. Thomson, G. Identifying complex disease genes: progress and paradigms. Nature Genet. 8, 108–110 (1994). (10.1038/ng1094-108) / Nature Genet. by G Thomson (1994)
  15. Suarez, B.K., Hampe, C.L. & Van Eeerdeweigh, P. Problems of replicating linkage claims in psychiatry. In Genetic approaches to mental disorders (eds. Gershon, E.S. & Cloninger, C.R.) 23–46 (American Psychiatric Association, Washington, DC, 1994). / Genetic approaches to mental disorders by BK Suarez (1994)
  16. Cox, D.R. & Hinkley, D.V. Theoretical Statistics(Chapman & Hall, 1974). (10.1007/978-1-4899-2887-0) / Theoretical Statistics by DR Cox (1974)
  17. Spielman, R.S., McGinnis, R.E. & Ewens, W.J. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellrtus (IDDM). Am. J. hum. Genet. 52, 506–516 (1993). / Am. J. hum. Genet. by RS Spielman (1993)
  18. Bennett, S.T. et al. Susceptibility to human type 1 diabetes at IDDM2is determined by tandem repeat variation at the insulin gene minisatellite locus. Nature Genet. 9, 284–92 (1995). (10.1038/ng0395-284) / Nature Genet. by ST Bennett (1995)
  19. Copeman, J.B. et al. Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31–q33. Nature Genet. 9, 80–85 (1995). (10.1038/ng0195-80) / Nature Genet. by JB Copeman (1995)
  20. Ewens, W.J. & Spielman, R.S. The transmission/disequilibrium test: history, subdivision, and admixture. Am. J. hum. Genet. 57, 455–464 (1995). (10.1002/ajmg.1320570319) / Am. J. hum. Genet. by WJ Ewens (1995)
  21. Gough, S.C.L. et al. Mutation of the glucagon receptor gene and diabetes mellitus in the UK: association or founder effect? Hum. mol. Genet. 4, 1609–1612 (1995). (10.1093/hmg/4.9.1609) / Hum. mol. Genet. by SCL Gough (1995)
  22. Thomson, G. Mapping disease genes: family-based association studies. Am. J. hum. Genet. 57, 487–498 (1995). / Am. J. hum. Genet. by G Thomson (1995)
  23. Terwilliger, J.D. & Ott, J. A multi-sample bootstrap approach to the estimation of maximized-over-models lod score distributions. Cytogenet. Cell Genet. 59, 142–144 (1992). (10.1159/000133228) / Cytogenet. Cell Genet. by JD Terwilliger (1992)
  24. Davies, J.L. et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371, 130–136 (1994). (10.1038/371130a0) / Nature by JL Davies (1994)
  25. Hashimoto, L. et al. Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome 11 q. Nature 371, 161–164 (1994). (10.1038/371161a0) / Nature by L Hashimoto (1994)
  26. Luo, D., Maclaren, N.K., Huang, H., Muir, A. & She, J. Intrafamilial and case-control association analyses of D2S152 in insulin-dependent diabetes mellitus. Autoimmunity (1995, in press). (10.3109/08916939508993363)
  27. Todd, J.A. Genetic analysis of type 1 diabetes using whole genome approaches. Proc. natn. Acad. Sci. U.S.A. 92, 8560–8565 (1995). (10.1073/pnas.92.19.8560) / Proc. natn. Acad. Sci. U.S.A. by JA Todd (1995)
  28. Luo, D. et al. Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25–q27. Am. J. hum. Genet. 57, 911–019 (1995). / Am. J. hum. Genet. by D Luo (1995)
  29. Wang, S. et al. Evidence for a susceptibility locus for schizophrenia on chromosome 6pter–p22. Nature Genet. 10, 41–46 (1995). (10.1038/ng0595-41) / Nature Genet. by S Wang (1995)
  30. Straub, R.E. et al. A potential vulnerability locus for schizophrenia on chromosome 6p24–22: evidence for genetic heterogeneity. Nature Genet. 11, 287–293 (1995). (10.1038/ng1195-287) / Nature Genet. by RE Straub (1995)
  31. Moises, H.W. et al. An international two-stage genome-wide search for schizophrenia susceptibility genes. Nature Genet. 11, 321–324 (1995). (10.1038/ng1195-321) / Nature Genet. by HW Moises (1995)
  32. Schwab, S.G. et al. Evaluation of a susceptibility gene for schizophrenia on chromosome 6p by multipoint affected sib-pair linkage analysis. Nature Genet. 11, 325–327 (1995). (10.1038/ng1195-325) / Nature Genet. by SG Schwab (1995)
  33. Gyapay, G. et al. The 1993–94 Genethon human genetic linkage map. Nature Genet. 7, 246–339 (1994). (10.1038/ng0694supp-246) / Nature Genet. by G Gyapay (1994)
  34. Kruglyak, L. & Lander, E.S. Complete multipoint sib pair analysis of qualitative and quantitative traits. Am. J. hum. Genet. 57, 439–454 (1995). / Am. J. hum. Genet. by L Kruglyak (1995)
  35. Kruglyak, L. & Lander, E.S. A nonparametric approach for mapping quantitative traitloci. Genetics 139, 1421–1428 (1995). (10.1093/genetics/139.3.1421) / Genetics by L Kruglyak (1995)
  36. Feingold, E. Markov processes for modeling and analyzing a new genetic mapping method. J. appl. Prob. 30, 766–779 (1993). (10.2307/3214511) / J. appl. Prob. by E Feingold (1993)
  37. R Asymptotic properties of affected-sib-pair linkage analysis. Am. J. hum. Genet. 52, 362–374 (1993).
  38. Lander, E.S. & Schork, N.J. Genetic dissection of complex traits. Science 265, 2037–2048 (1994). (10.1126/science.8091226) / Science by ES Lander (1994)
Dates
Type When
Created 21 years ago (Aug. 18, 2004, 4:06 p.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 5:19 p.m.)
Indexed 2 weeks, 6 days ago (Aug. 7, 2025, 4:26 p.m.)
Issued 29 years, 9 months ago (Nov. 1, 1995)
Published 29 years, 9 months ago (Nov. 1, 1995)
Published Print 29 years, 9 months ago (Nov. 1, 1995)
Funders 0

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@article{Lander_1995, title={Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results}, volume={11}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng1195-241}, DOI={10.1038/ng1195-241}, number={3}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Lander, Eric and Kruglyak, Leonid}, year={1995}, month=nov, pages={241–247} }