DOI: 10.1038/ng1195-230. Presenilins and Alzheimer disease

Presenilins and Alzheimer disease

10.1038/ng1195-230

Crossref journal-article

Springer Science and Business Media LLC

Nature Genetics (297)

Bibliography

Broeckhoven, C. V. (1995). Presenilins and Alzheimer disease. Nature Genetics, 11(3), 230â232.

Authors 1

Christine Van Broeckhoven (first)

References 15 Referenced 148

Goate, A. et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704–706 (1991). (10.1038/349704a0) / Nature by A Goate (1991)
Van Broeckhoven, C. Molecular genetics of Alzheimer disease: identification of genes and gene mutations. Eur. Neurol. 35, 8–19 (1995). (10.1159/000117083) / Eur. Neurol. by C Van Broeckhoven (1995)
Sherrington, R. et al. Cloning of a gene bearing mis-sense mutations in early-onset familial Alzheimer's disease. Nature 375, 754–760 (1995). (10.1038/375754a0) / Nature by R Sherrington (1995)
Alzheimer's Disease Collaborative Group. The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Nature Genet. 11, 219–222 (1995). (10.1038/ng1095-219)
Cruts, M. et al. Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3. Hum. molec. Genet. (in the press). (10.1093/hmg/4.12.2363)
Campion, D. et al. Mutations of the Presenilin-1 gene in families with early-onset Alzheimer's disease. Hum. molec. Genet. (in the press). (10.1093/hmg/4.12.2373)
Tanahashi, H. et al. Missense mutation of S182 gene in Japanese familial Alzheimer's disease. The Lancet 346, 440 (1995). (10.1016/S0140-6736(95)92810-3) / The Lancet by H Tanahashi (1995)
Levy-Lahad, E. et al. A familial Alzheimer's disease locus on chromosome 1. Science 269, 970–973 (1995). (10.1126/science.7638621) / Science by E Levy-Lahad (1995)
Levy-Lahad, E. et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269, 973–977 (1995). (10.1126/science.7638622) / Science by E Levy-Lahad (1995)
Rogaev, E.I. et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775–778 (1995). (10.1038/376775a0) / Nature by EI Rogaev (1995)
Levitan, D. & Greenwald, I. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377, 351–354 (1995). (10.1038/377351a0) / Nature by D Levitan (1995)
Artavanis-Tsakonas, S., Matsuno, K. & Fortini, M.E. Notch signaling. Science 268, 225–232 (1995). (10.1126/science.7716513) / Science by S Artavanis-Tsakonas (1995)
Scheuner, D. et al. Fibroblasts from carriers of familial AD linked to chromosome 14 show increased Aβ production. Soc. Neurosci. Abstr. 21, 1500 (1995). / Soc. Neurosci. Abstr. by D Scheuner (1995)
Sorbi, S. et al. Missense mutation of S182 gene in Italian families with early-onset Alzheimer's disease. Lancet 346, 439–440 (1995). (10.1016/S0140-6736(95)92809-X) / Lancet by S Sorbi (1995)
Wasco, W. et al. Familial Alzheimer's chromosome 14 mutations. Nature Med. 1, 848 (1995). (10.1038/nm0995-848a) / Nature Med. by W Wasco (1995)

Dates

Type	When
Created	21 years ago (Aug. 18, 2004, 4:06 p.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 5:19 p.m.)
Indexed	2 weeks, 3 days ago (Aug. 6, 2025, 9:12 a.m.)
Issued	29 years, 9 months ago (Nov. 1, 1995)
Published	29 years, 9 months ago (Nov. 1, 1995)
Published Print	29 years, 9 months ago (Nov. 1, 1995)

Funders 0

None

BibTeX

@article{Broeckhoven_1995, title={Presenilins and Alzheimer disease}, volume={11}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng1195-230}, DOI={10.1038/ng1195-230}, number={3}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Broeckhoven, Christine Van}, year={1995}, month=nov, pages={230–232} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        6
      ]
    ],
    "date-time": "2025-08-06T13:12:41Z",
    "timestamp": 1754485961197
  },
  "reference-count": 15,
  "publisher": "Springer Science and Business Media LLC",
  "issue": "3",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1995,
            11,
            1
          ]
        ],
        "date-time": "1995-11-01T00:00:00Z",
        "timestamp": 815184000000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "http://www.springer.com/tdm"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1995,
        11
      ]
    ]
  },
  "DOI": "10.1038/ng1195-230",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2004,
        8,
        18
      ]
    ],
    "date-time": "2004-08-18T20:06:00Z",
    "timestamp": 1092859560000
  },
  "page": "230-232",
  "source": "Crossref",
  "is-referenced-by-count": 148,
  "title": "Presenilins and Alzheimer disease",
  "prefix": "10.1038",
  "volume": "11",
  "author": [
    {
      "given": "Christine Van",
      "family": "Broeckhoven",
      "sequence": "first",
      "affiliation": []
    }
  ],
  "member": "297",
  "reference": [
    {
      "key": "BFng1195230_CR1",
      "doi-asserted-by": "publisher",
      "first-page": "704",
      "DOI": "10.1038/349704a0",
      "volume": "349",
      "author": "A Goate",
      "year": "1991",
      "unstructured": "Goate, A. et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704\u2013706 (1991).",
      "journal-title": "Nature"
    },
    {
      "key": "BFng1195230_CR2",
      "doi-asserted-by": "publisher",
      "first-page": "8",
      "DOI": "10.1159/000117083",
      "volume": "35",
      "author": "C Van Broeckhoven",
      "year": "1995",
      "unstructured": "Van Broeckhoven, C. Molecular genetics of Alzheimer disease: identification of genes and gene mutations. Eur. Neurol. 35, 8\u201319 (1995).",
      "journal-title": "Eur. Neurol."
    },
    {
      "key": "BFng1195230_CR3",
      "doi-asserted-by": "publisher",
      "first-page": "754",
      "DOI": "10.1038/375754a0",
      "volume": "375",
      "author": "R Sherrington",
      "year": "1995",
      "unstructured": "Sherrington, R. et al. Cloning of a gene bearing mis-sense mutations in early-onset familial Alzheimer's disease. Nature 375, 754\u2013760 (1995).",
      "journal-title": "Nature"
    },
    {
      "key": "BFng1195230_CR4",
      "doi-asserted-by": "crossref",
      "unstructured": "Alzheimer's Disease Collaborative Group. The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Nature Genet. 11, 219\u2013222 (1995).",
      "DOI": "10.1038/ng1095-219"
    },
    {
      "key": "BFng1195230_CR5",
      "doi-asserted-by": "crossref",
      "unstructured": "Cruts, M. et al. Molecular genetic analysis of familial early-onset Alzheimer's disease linked to chromosome 14q24.3. Hum. molec. Genet. (in the press).",
      "DOI": "10.1093/hmg/4.12.2363"
    },
    {
      "key": "BFng1195230_CR6",
      "doi-asserted-by": "crossref",
      "unstructured": "Campion, D. et al. Mutations of the Presenilin-1 gene in families with early-onset Alzheimer's disease. Hum. molec. Genet. (in the press).",
      "DOI": "10.1093/hmg/4.12.2373"
    },
    {
      "key": "BFng1195230_CR7",
      "doi-asserted-by": "publisher",
      "first-page": "440",
      "DOI": "10.1016/S0140-6736(95)92810-3",
      "volume": "346",
      "author": "H Tanahashi",
      "year": "1995",
      "unstructured": "Tanahashi, H. et al. Missense mutation of S182 gene in Japanese familial Alzheimer's disease. The Lancet 346, 440 (1995).",
      "journal-title": "The Lancet"
    },
    {
      "key": "BFng1195230_CR8",
      "doi-asserted-by": "publisher",
      "first-page": "970",
      "DOI": "10.1126/science.7638621",
      "volume": "269",
      "author": "E Levy-Lahad",
      "year": "1995",
      "unstructured": "Levy-Lahad, E. et al. A familial Alzheimer's disease locus on chromosome 1. Science 269, 970\u2013973 (1995).",
      "journal-title": "Science"
    },
    {
      "key": "BFng1195230_CR9",
      "doi-asserted-by": "publisher",
      "first-page": "973",
      "DOI": "10.1126/science.7638622",
      "volume": "269",
      "author": "E Levy-Lahad",
      "year": "1995",
      "unstructured": "Levy-Lahad, E. et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science 269, 973\u2013977 (1995).",
      "journal-title": "Science"
    },
    {
      "key": "BFng1195230_CR10",
      "doi-asserted-by": "publisher",
      "first-page": "775",
      "DOI": "10.1038/376775a0",
      "volume": "376",
      "author": "EI Rogaev",
      "year": "1995",
      "unstructured": "Rogaev, E.I. et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775\u2013778 (1995).",
      "journal-title": "Nature"
    },
    {
      "key": "BFng1195230_CR11",
      "doi-asserted-by": "publisher",
      "first-page": "351",
      "DOI": "10.1038/377351a0",
      "volume": "377",
      "author": "D Levitan",
      "year": "1995",
      "unstructured": "Levitan, D. & Greenwald, I. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377, 351\u2013354 (1995).",
      "journal-title": "Nature"
    },
    {
      "key": "BFng1195230_CR12",
      "doi-asserted-by": "publisher",
      "first-page": "225",
      "DOI": "10.1126/science.7716513",
      "volume": "268",
      "author": "S Artavanis-Tsakonas",
      "year": "1995",
      "unstructured": "Artavanis-Tsakonas, S., Matsuno, K. & Fortini, M.E. Notch signaling. Science 268, 225\u2013232 (1995).",
      "journal-title": "Science"
    },
    {
      "key": "BFng1195230_CR13",
      "first-page": "1500",
      "volume": "21",
      "author": "D Scheuner",
      "year": "1995",
      "unstructured": "Scheuner, D. et al. Fibroblasts from carriers of familial AD linked to chromosome 14 show increased A\u03b2 production. Soc. Neurosci. Abstr. 21, 1500 (1995).",
      "journal-title": "Soc. Neurosci. Abstr."
    },
    {
      "key": "BFng1195230_CR14",
      "doi-asserted-by": "publisher",
      "first-page": "439",
      "DOI": "10.1016/S0140-6736(95)92809-X",
      "volume": "346",
      "author": "S Sorbi",
      "year": "1995",
      "unstructured": "Sorbi, S. et al. Missense mutation of S182 gene in Italian families with early-onset Alzheimer's disease. Lancet 346, 439\u2013440 (1995).",
      "journal-title": "Lancet"
    },
    {
      "key": "BFng1195230_CR15",
      "doi-asserted-by": "publisher",
      "first-page": "848",
      "DOI": "10.1038/nm0995-848a",
      "volume": "1",
      "author": "W Wasco",
      "year": "1995",
      "unstructured": "Wasco, W. et al. Familial Alzheimer's chromosome 14 mutations. Nature Med. 1, 848 (1995).",
      "journal-title": "Nature Med."
    }
  ],
  "container-title": "Nature Genetics",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "http://www.nature.com/articles/ng1195-230",
      "content-type": "text/html",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://www.nature.com/articles/ng1195-230.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://www.nature.com/articles/ng1195-230.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        5,
        18
      ]
    ],
    "date-time": "2023-05-18T21:19:22Z",
    "timestamp": 1684444762000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://www.nature.com/articles/ng1195-230"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1995,
        11
      ]
    ]
  },
  "references-count": 15,
  "journal-issue": {
    "issue": "3",
    "published-print": {
      "date-parts": [
        [
          1995,
          11
        ]
      ]
    }
  },
  "alternative-id": [
    "BFng1195230"
  ],
  "URL": "http://dx.doi.org/10.1038/ng1195-230",
  "relation": {},
  "ISSN": [
    "1061-4036",
    "1546-1718"
  ],
  "subject": [],
  "container-title-short": "Nat Genet",
  "published": {
    "date-parts": [
      [
        1995,
        11
      ]
    ]
  }
}