DOI: 10.1038/ng1159. Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss

Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss

10.1038/ng1159

Crossref journal-article

Springer Science and Business Media LLC

Nature Genetics (297)

Bibliography

Modrek, B., & Lee, C. J. (2003). Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss. Nature Genetics, 34(2), 177â180.

Authors 2

Barmak Modrek (first)
Christopher J Lee (additional)

References 18 Referenced 397

Tatusov, R.L., Koonin, E.V. & Lipman, D.J. A genomic perspective on protein families. Science 278, 631–637 (1997). (10.1126/science.278.5338.631) / Science by RL Tatusov (1997)
Brett, D., Pospisil, H., Valcarcel, J., Reich, J. & Bork, P. Alternative splicing and genome complexity. Nat. Genet. 30, 29–30 (2002). (10.1038/ng803) / Nat. Genet. by D Brett (2002)
Mironov, A.A., Fickett, J.W. & Gelfand, M.S. Frequent alternative splicing of human genes. Genome Res. 9, 1288–1293 (1999). (10.1101/gr.9.12.1288) / Genome Res. by AA Mironov (1999)
Brett, D. et al. EST comparison indicates 38% of human mRNAs contain possible alternative splice forms. FEBS Lett. 474, 83–86 (2000). (10.1016/S0014-5793(00)01581-7) / FEBS Lett. by D Brett (2000)
Croft, L. et al. ISIS, the intron information system, reveals the high frequency of alternative splicing in the human genome. Nat. Genet. 24, 340–341 (2000). (10.1038/74153) / Nat. Genet. by L Croft (2000)
International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 409, 860–921 (2001). (10.1038/35057062)
Kan, Z., Rouchka, E.C., Gish, W.R. & States, D.J. Gene structure prediction and alternative splicing analysis using genomically aligned ESTs. Genome Res. 11, 889–900 (2001). (10.1101/gr.155001) / Genome Res. by Z Kan (2001)
Modrek, B., Resch, A., Grasso, C. & Lee, C. Genome-wide analysis of alternative splicing using human expressed sequence data. Nucleic Acids Res. 29, 2850–2859 (2001). (10.1093/nar/29.13.2850) / Nucleic Acids Res. by B Modrek (2001)
Xu, Q., Modrek, B. & Lee, C. Genome-wide detection of tissue-specific alternative splicing in the human transcriptome. Nucleic Acids Res. 30, 3754–3766 (2002). (10.1093/nar/gkf492) / Nucleic Acids Res. by Q Xu (2002)
Wheeler, D.L. et al. Database resources of the National Center for Biotechnology Information: 2002 update. Nucleic Acids Res. 30, 13–16 (2002). (10.1093/nar/30.1.13) / Nucleic Acids Res. by DL Wheeler (2002)
Batzoglou, S., Pachter, L., Mezirov, J.P., Berger, B. & Lander, E.S. Human and mouse gene structure: comparative analysis and application to exon prediction. Genome Res. 10, 950–958 (2000). (10.1101/gr.10.7.950) / Genome Res. by S Batzoglou (2000)
Green, P. et al. Ancient conserved regions in new gene sequences and the protein databases. Science 259, 1711–1716 (1993). (10.1126/science.8456298) / Science by P Green (1993)
Hastings, M.L. & Krainer, A.R. Pre-mRNA splicing in the new millennium. Curr. Opin. Cell. Biol. 13, 302–309 (2001). (10.1016/S0955-0674(00)00212-X) / Curr. Opin. Cell. Biol. by ML Hastings (2001)
Britten, R.J. Rates of DNA sequence evolution differ between taxonomic groups. Science 231, 1393–1398 (1986). (10.1126/science.3082006) / Science by RJ Britten (1986)
Cui, Y., Wong, W.H., Bornberg-Bauer, E. & Chan, H.S. Recombinatoric exploration of novel folded structures: a heteropolymer-based model of protein evolutionary landscapes. Proc. Natl. Acad. Sci. USA 99, 809–814 (2002). (10.1073/pnas.022240299) / Proc. Natl. Acad. Sci. USA by Y Cui (2002)
Schuler, G. Pieces of the puzzle: expressed sequence tags and the catalog of human genes. J. Mol. Med. 75, 694–698 (1997). (10.1007/s001090050155) / J. Mol. Med. by G Schuler (1997)
Needleman, S.B. & Wunsch, C.D. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J. Mol. Biol. 48, 443–453 (1970). (10.1016/0022-2836(70)90057-4) / J. Mol. Biol. by SB Needleman (1970)
Lee, C., Grasso, C. & Sharlow, M. Multiple sequence alignment using partial order graphs. Bioinformatics 18, 452–464 (2002). (10.1093/bioinformatics/18.3.452) / Bioinformatics by C Lee (2002)

Dates

Type	When
Created	22 years, 3 months ago (May 23, 2003, 11:12 a.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 5:18 p.m.)
Indexed	33 minutes ago (Aug. 30, 2025, 10:56 a.m.)
Issued	22 years, 3 months ago (May 5, 2003)
Published	22 years, 3 months ago (May 5, 2003)
Published Online	22 years, 3 months ago (May 5, 2003)
Published Print	22 years, 2 months ago (June 1, 2003)

Funders 0

None

BibTeX

@article{Modrek_2003, title={Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss}, volume={34}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng1159}, DOI={10.1038/ng1159}, number={2}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Modrek, Barmak and Lee, Christopher J}, year={2003}, month=may, pages={177–180} }

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