The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins
10.1038/ng0396-260
Crossref journal-article
Springer Science and Business Media LLC
Nature Genetics (297)
Bibliography

Ebersole, T. A., Chen, Q., Justice, M. J., & Artzt, K. (1996). The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins. Nature Genetics, 12(3), 260–265.

Authors 4
  1. Thomas A. Ebersole (first)
  2. Qi Chen (additional)
  3. Monica J. Justice (additional)
  4. Karen Artzt (additional)
References 42 Referenced 282
  1. Bennett, D. Developmental analysis of a mutation with pleiottopic effects in the mouse. J. Morph. 96, 199–234 (1956). (10.1002/jmor.1050980202) / J. Morph. by D Bennett (1956)
  2. Sidman, R.L., Dickie, M.M. & Appel, S.H. Mutant mice (quaking and jimpy) with deficient myelination in the central nervous system. Science. 144, 309–311 (1964). (10.1126/science.144.3616.309) / Science. by RL Sidman (1964)
  3. Friedrich, Jr V.L. The myelin deficit in quaking mice. Brain Res. 82, 168–172 (1974). (10.1016/0006-8993(74)90902-0) / Brain Res. by VL Friedrich Jr (1974)
  4. Bennett, W.J., Gall, A.M., Southard, J.L. & Sidman, R.L. Abnormal spermtogenesis in quaking, a myelin-deficient mutant mouse. Biol. Reprod. 5, 30–58 (1971). (10.1093/biolreprod/5.1.30) / Biol. Reprod. by WJ Bennett (1971)
  5. Ebersole, T., Rho, O. & Artzt, K. The proximal end of mouse chromosome 17: New molecular markers identify a deletion associated with quakingviable. Genetics. 131, 183–190 (1992). (10.1093/genetics/131.1.183) / Genetics. by T Ebersole (1992)
  6. Bode, V.C. Ethylnitrosourea mutagenesis and the isolation of mutant alleles for specific genes located in the T region of mouse chromosome 17. Genetics 108, 457–470 (1984). (10.1093/genetics/108.2.457) / Genetics by VC Bode (1984)
  7. Justice, M.J. & Bode, V.C. Induction of new mutations in a mouse t-haplotype using ethylnttrosourea mutagenesis. Genet. Res. Camb. 47, 187–192 (1986). (10.1017/S0016672300023119) / Genet. Res. Camb. by MJ Justice (1986)
  8. Shedlovsky, A., King, T.R. & Dove, W.F. Saturation germ line mutagenesis of the murine t region including a lethal allele at the quaking locus. Proc. Natl. Acad. Sci. USA. 85, 180–184 (1988). (10.1073/pnas.85.1.180) / Proc. Natl. Acad. Sci. USA. by A Shedlovsky (1988)
  9. Justice, M.J. & Bode, V.C., ENU-induced alleles of the murine quaking locus are recessive embryonic lethal mutations. Genet. Res. Camb. 51, 95–102 (1988). (10.1017/S0016672300024101) / Genet. Res. Camb. by MJ Justice (1988)
  10. Gibson, T.J., Thompson, J.D. & Heringa, J. The KH domain occurs in a diverse set of RNA-binding proteins that include the antiterminator NusA and is probably involved in binding to nucleic acid. FEBS. 324, 361–366 (1993). (10.1016/0014-5793(93)80152-K) / FEBS. by TJ Gibson (1993)
  11. Siomi, H., Matunis, M.J., Michael, W.M. & Dreyfuss, G. The pre-mRNA binding K protein contains a novel evolutionary conserved motif. Nucl. Adds Res. 21, 1193–1198 (1993). (10.1093/nar/21.5.1193) / Nucl. Adds Res. by H Siomi (1993)
  12. Burd, C.G. & Dreyfuss, G. Conserved structures and diversity of functions of RNA-blndingproteins. science 266, 615–621 (1994). (10.1126/science.8036511) / science by CG Burd (1994)
  13. Wong, G. et al. Molecular cloning and nucleic acid binding properties of the GAP-associated Tyrosine Phosphoprotein p62. Cell 69, 551–558 (1992). (10.1016/0092-8674(92)90455-L) / Cell by G Wong (1992)
  14. Fumagalli, S., Totty, N.F., Hsuan, J.J. & Courtneidge, S.A. A target for Src in mitosis. Nature 368, 871–874 (1994). (10.1038/368871a0) / Nature by S Fumagalli (1994)
  15. Taylor, S.J. & ShaJloway, D., RNA-bindlng protein associated with Src through its SH2 and SH3 domains in mitosis. Nature. 368, 867–871 (1994). (10.1038/368867a0) / Nature. by SJ Taylor (1994)
  16. Ogawa, W., Hosomi, Y., Shii, K. & Roth, R.A. Evidence for two distinct 60-kilodalton substrates of the SRC tyrosine kinase. J. Biol. Chem. 289, 29602–29608 (1994). (10.1016/S0021-9258(18)43923-3) / J. Biol. Chem. by W Ogawa (1994)
  17. Jones, A.R. & Schedl, T. Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68. Genes Devel. 9, 1491–1504 (1995). (10.1101/gad.9.12.1491) / Genes Devel. by AR Jones (1995)
  18. Kiledjian, M. & Dreyfuss, G. Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. EMBO J. 11, 2655–2664 (1992). (10.1002/j.1460-2075.1992.tb05331.x) / EMBO J. by M Kiledjian (1992)
  19. Yu, H. et al. Structural basis for the binding of proline-rich peptides to SH3 domains. Cell 76, 933–945 (1994). (10.1016/0092-8674(94)90367-0) / Cell by H Yu (1994)
  20. Feng, S., Chen, J.K., Yu, H., Simon, J.A. & Schreiber, S.L. Two binding orientations for peptides to the Src SH3 domain: Development of a general model for SH3-llgand interactions. Science 266, 1241–1247 (1994). (10.1126/science.7526465) / Science by S Feng (1994)
  21. Weng, Z. et al. Identification of Src, Fyn, and Lyn SHS-binding proteins: Implications for a function of SH3 domains. Mol. Cell. Biol. 14, 4509–4521 (1994). (10.1128/MCB.14.7.4509) / Mol. Cell. Biol. by Z Weng (1994)
  22. Hobert, 0., JaJal, B., Schlessinger, J. & Ulrich, A. Novel signaling pathway suggested by SH3 domain-mediated p95vav/heterogeneous ribonucleoprotein K interaction. J. Biol. Chem. 269, 20225–20228 (1994). (10.1016/S0021-9258(17)31979-8) / J. Biol. Chem. by 0 Hobert (1994)
  23. Ashley, C.T. et al. Human and murine FMR-1: Alternative splicing and translational initiation downstream of the CGG-repeat. Nature Genet. 4, 244–251 (1994). (10.1038/ng0793-244) / Nature Genet. by CT Ashley (1994)
  24. Siomi, H., Choi, M., Siomi, M.C., Nussbaum, R.L. & Dreyfuss, G. Essential role for KH domains in RNA binding: Impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome. Cell 77, 33–39 (1994). (10.1016/0092-8674(94)90232-1) / Cell by H Siomi (1994)
  25. Timsit, S., Martinez, S., Allinquant, B., Peyron, F., Puelles, L. & Zalc, B. Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression. J. Neurosci. 15, 1012–1024 (1995). (10.1523/JNEUROSCI.15-02-01012.1995) / J. Neurosci. by S Timsit (1995)
  26. Darnell, Jr J.E., Kerr, M. & Stark, G.R. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science. 264, 1415–1421 (1994). (10.1126/science.8197455) / Science. by JE Darnell Jr (1994)
  27. Umemori, H., Sato, S., Yagi, T., Aizawa, S & Yamamoto, T. Initial events of myelination involve Fyn tyrosine kinase signalling. Nature 367, 572–576 (1994). (10.1038/367572a0) / Nature by H Umemori (1994)
  28. Richard, S. et al. Association of p62, a multifunctional SH2-binding and SH3-binding protein, with src family tyrosine kinases, Grb2, and phospholipase Cλ-1. Mol. Cell. Biol. 15, 186–197 (1995). (10.1128/MCB.15.1.186) / Mol. Cell. Biol. by S Richard (1995)
  29. Hill, M.A., Schedlich, L. & Gunning, P. Serum-induced signal transduction determines the peripheral location of β-actin mRNA within the cell. J.Cell.Biol. 126, 1221–1230 (1994). (10.1083/jcb.126.5.1221) / J.Cell.Biol. by MA Hill (1994)
  30. Steward, O. Dendrites as compartments for macromolecular synthesis. Proc. Natl. Acad. Sci. USA 91, 10766–10768 (1994). (10.1073/pnas.91.23.10766) / Proc. Natl. Acad. Sci. USA by O Steward (1994)
  31. Mayeda, A., Munroe, S.H., Cáceres, J.F. & Krainer, A.R. Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins. EMBO J. 13, 5483–5495 (1994). (10.1002/j.1460-2075.1994.tb06883.x) / EMBO J. by A Mayeda (1994)
  32. Fujita, N. et al. Developmentally regulated alternative splicing of brain myelin-associated glycoprotein mRNA is lacking in the quaking mouse. FEBS. 232, 323–327 (1988). (10.1016/0014-5793(88)80762-2) / FEBS. by N Fujita (1988)
  33. Fujita, N. et al. The large isoform of myelin-associated glycoprotein is scarcely expressed in the quaking mouse brain. J. Neurochem. 55, 1056–1059 (1990). (10.1111/j.1471-4159.1990.tb04596.x) / J. Neurochem. by N Fujita (1990)
  34. Campagnoni, A.T. et al. Structure and developmental regulation of Golli-mbp, a 105-kilobase gene that encompasses the myelin basic protein gene and is expressed in cells in the oligodendrocyte lineage in the brain. J. Biol. Chem. 268, 4930–4938 (1993). (10.1016/S0021-9258(18)53485-2) / J. Biol. Chem. by AT Campagnoni (1993)
  35. Ikenaka, K., Kagawa, T. & Mikoshiba, K. Selective expression of DM-20, an alternatively spliced myelin proteolipid gene product, in developing nervous sytem of the mouse. J. Neurochem. 58, 2248–2253 (1992). (10.1111/j.1471-4159.1992.tb10970.x) / J. Neurochem. by K Ikenaka (1992)
  36. DeWille, J.W. & Farmer, S.J. Quaking phenotype influences brain lipid-related mRNA levels. Neurosci. Lett. 141, 195–198 (1992). (10.1016/0304-3940(92)90893-C) / Neurosci. Lett. by JW DeWille (1992)
  37. Crenshaw III, E.B., Russo, A.F., Swanson, L.W. & Rosenfeld, M.G. Neuron-specific alternative RNA processing in transgenic mice expressing a methallothionein-calcitonin fusion gene. Cell 49, 389–398 (1987). (10.1016/0092-8674(87)90291-1) / Cell by EB Crenshaw III (1987)
  38. Rossi, J.M. et al. Genomic analysis using a yeast artificial chromosome library with mouse DNA inserts. Proc. Natl. Acad. Sci. USA 89, 2456–2460 (1992). (10.1073/pnas.89.6.2456) / Proc. Natl. Acad. Sci. USA by JM Rossi (1992)
  39. Riley, J. et al. A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. Nucl. Acids Res. 18, 2887–2890 (1990). (10.1093/nar/18.10.2887) / Nucl. Acids Res. by J Riley (1990)
  40. Enrich, E., Craig, A., Poustka, A., Frischauf, A.-M. & Lehrach, H. A family of cosmid vectors with the multi-copy R6K replication origin. Gene 57, 229–237 (1987). (10.1016/0378-1119(87)90126-0) / Gene by E Enrich (1987)
  41. Wilkinson, D.G. Whole mount in situ hybridization of vertebrate embryos. In situ Hybridization, A Practical Approach (ed Wilkinson, D.G.) 75–83 (IRL Press, New York, 1992). / situ Hybridization, A Practical Approach by DG Wilkinson (1992)
  42. Yan, Y., Lagenaur, C. & Narayanan, V. Molecular cloning of M6: Identification of a PLP/DM20 gene family. Neuron. 11, 423–431 (1993). (10.1016/0896-6273(93)90147-J) / Neuron. by Y Yan (1993)
Dates
Type When
Created 21 years ago (Aug. 18, 2004, 4:06 p.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 4:25 p.m.)
Indexed 1 week ago (Aug. 23, 2025, 9:12 p.m.)
Issued 29 years, 5 months ago (March 1, 1996)
Published 29 years, 5 months ago (March 1, 1996)
Published Print 29 years, 5 months ago (March 1, 1996)
Funders 0

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@article{Ebersole_1996, title={The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins}, volume={12}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng0396-260}, DOI={10.1038/ng0396-260}, number={3}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Ebersole, Thomas A. and Chen, Qi and Justice, Monica J. and Artzt, Karen}, year={1996}, month=mar, pages={260–265} }