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References
54
Referenced
133
-
Sauvageau, M. & Sauvageau, G. Polycomb group genes: keeping stem cell activity in balance. PLoS Biol. 6, e113 (2008).
(
10.1371/journal.pbio.0060113
) / PLoS Biol. by M Sauvageau (2008) -
Valk-Lingbeek, M.E., Bruggeman, S.W. & van Lohuizen, M. Stem cells and cancer; the polycomb connection. Cell 118, 409–418 (2004).
(
10.1016/j.cell.2004.08.005
) / Cell by ME Valk-Lingbeek (2004) -
Harvey, K.F., Pfleger, C.M. & Hariharan, I.K. The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell 114, 457–467 (2003).
(
10.1016/S0092-8674(03)00557-9
) / Cell by KF Harvey (2003) -
Brumby, A.M. & Richardson, H.E. scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J. 22, 5769–5779 (2003).
(
10.1093/emboj/cdg548
) / EMBO J. by AM Brumby (2003) -
Hariharan, I.K. & Bilder, D. Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila. Annu. Rev. Genet. 40, 335–361 (2006).
(
10.1146/annurev.genet.39.073003.100738
) / Annu. Rev. Genet. by IK Hariharan (2006) -
Newsome, T.P., Asling, B. & Dickson, B.J. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development 127, 851–860 (2000).
(
10.1242/dev.127.4.851
) / Development by TP Newsome (2000) -
Brunk, B.P., Martin, E.C. & Adler, P.N. Drosophila genes Posterior Sex Combs and Suppressor two of zeste encode proteins with homology to the murine bmi-1 oncogene. Nature 353, 351–353 (1991).
(
10.1038/353351a0
) / Nature by BP Brunk (1991) -
Beuchle, D., Struhl, G. & Muller, J. Polycomb group proteins and heritable silencing of Drosophila Hox genes. Development 128, 993–1004 (2001).
(
10.1242/dev.128.6.993
) / Development by D Beuchle (2001) -
Wu, C.T. & Howe, M. A genetic analysis of the Suppressor 2 of zeste complex of Drosophila melanogaster. Genetics 140, 139–181 (1995).
(
10.1093/genetics/140.1.139
) / Genetics by CT Wu (1995) -
Lo, S.M., Ahuja, N.K. & Francis, N.J. Polycomb group protein suppressor 2 of zeste is a functional homolog of posterior sex combs. Mol. Cell Biol. 29, 515–525 (2008).
(
10.1128/MCB.01044-08
) / Mol. Cell Biol. by SM Lo (2008) -
Schwartz, Y.B. & Pirrotta, V. Polycomb silencing mechanisms and the management of genomic programmes. Nat. Rev. Genet. 8, 9–22 (2007).
(
10.1038/nrg1981
) / Nat. Rev. Genet. by YB Schwartz (2007) -
Schuettengruber, B., Chourrout, D., Vervoort, M., Leblanc, B. & Cavalli, G. Genome regulation by polycomb and trithorax proteins. Cell 128, 735–745 (2007).
(
10.1016/j.cell.2007.02.009
) / Cell by B Schuettengruber (2007) -
Grimaud, C., Negre, N. & Cavalli, G. From genetics to epigenetics: the tale of Polycomb group and trithorax group genes. Chromosome Res. 14, 363–375 (2006).
(
10.1007/s10577-006-1069-y
) / Chromosome Res. by C Grimaud (2006) -
Oktaba, K. et al. Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila. Dev. Cell 15, 877–889 (2008).
(
10.1016/j.devcel.2008.10.005
) / Dev. Cell by K Oktaba (2008) -
Ringrose, L. Polycomb comes of age: genome-wide profiling of target sites. Curr. Opin. Cell Biol. 19, 290–297 (2007).
(
10.1016/j.ceb.2007.04.010
) / Curr. Opin. Cell Biol. by L Ringrose (2007) -
Schwartz, Y.B. et al. Genome-wide analysis of Polycomb targets in Drosophila melanogaster. Nat. Genet. 38, 700–705 (2006).
(
10.1038/ng1817
) / Nat. Genet. by YB Schwartz (2006) -
Tolhuis, B. et al. Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster. Nat. Genet. 38, 694–699 (2006).
(
10.1038/ng1792
) / Nat. Genet. by B Tolhuis (2006) -
Janody, F. et al. A mosaic genetic screen reveals distinct roles for trithorax and polycomb group genes in Drosophila eye development. Genetics 166, 187–200 (2004).
(
10.1534/genetics.166.1.187
) / Genetics by F Janody (2004) -
Martinez, A.M. & Cavalli, G. The role of polycomb group proteins in cell cycle regulation during development. Cell Cycle 5, 1189–1197 (2006).
(
10.4161/cc.5.11.2781
) / Cell Cycle by AM Martinez (2006) -
Martinez, A.M., Colomb, S., Dejardin, J., Bantignies, F. & Cavalli, G. Polycomb group-dependent Cyclin A repression in Drosophila. Genes Dev. 20, 501–513 (2006).
(
10.1101/gad.357106
) / Genes Dev. by AM Martinez (2006) -
Grewal, S.S., Li, L., Orian, A., Eisenman, R.N. & Edgar, B.A. Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nat. Cell Biol. 7, 295–302 (2005).
(
10.1038/ncb1223
) / Nat. Cell Biol. by SS Grewal (2005) -
Tseng, A.S. et al. Capicua regulates cell proliferation downstream of the receptor tyrosine kinase/ras signaling pathway. Curr. Biol. 17, 728–733 (2007).
(
10.1016/j.cub.2007.03.023
) / Curr. Biol. by AS Tseng (2007) -
Tanimoto, H., Itoh, S., ten Dijke, P. & Tabata, T. Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs. Mol. Cell 5, 59–71 (2000).
(
10.1016/S1097-2765(00)80403-7
) / Mol. Cell by H Tanimoto (2000) -
Nellesen, D.T., Lai, E.C. & Posakony, J.W. Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators. Dev. Biol. 213, 33–53 (1999).
(
10.1006/dbio.1999.9324
) / Dev. Biol. by DT Nellesen (1999) -
Willecke, M. et al. The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size. Curr. Biol. 16, 2090–2100 (2006).
(
10.1016/j.cub.2006.09.005
) / Curr. Biol. by M Willecke (2006) -
Bach, E.A. et al. GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo. Gene Expr. Patterns 7, 323–331 (2007).
(
10.1016/j.modgep.2006.08.003
) / Gene Expr. Patterns by EA Bach (2007) -
Goodliffe, J.M., Wieschaus, E. & Cole, M.D. Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila. Genes Dev. 19, 2941–2946 (2005).
(
10.1101/gad.1352305
) / Genes Dev. by JM Goodliffe (2005) -
Sun, Y.H. et al. White as a reporter gene to detect transcriptional silencers specifying position-specific gene expression during Drosophila melanogaster eye development. Genetics 141, 1075–1086 (1995).
(
10.1093/genetics/141.3.1075
) / Genetics by YH Sun (1995) -
Bach, E.A., Vincent, S., Zeidler, M.P. & Perrimon, N. A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics 165, 1149–1166 (2003).
(
10.1093/genetics/165.3.1149
) / Genetics by EA Bach (2003) -
Ekas, L.A., Baeg, G.H., Flaherty, M.S., Ayala-Camargo, A. & Bach, E.A. JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila. Development 133, 4721–4729 (2006).
(
10.1242/dev.02675
) / Development by LA Ekas (2006) -
Tsai, Y.C. & Sun, Y.H. Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development. Genesis 39, 141–153 (2004).
(
10.1002/gene.20035
) / Genesis by YC Tsai (2004) -
Sehnal, F. & Bryant, P.J. Delayed pupariation in Drosophila imaginal disc overgrowth mutants is associated with reduced ecdysteroid titer. J. Insect Physiol. 39, 1051–1059 (1993).
(
10.1016/0022-1910(93)90129-F
) / J. Insect Physiol. by F Sehnal (1993) -
Menut, L. et al. A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation. Genetics 177, 1667–1677 (2007).
(
10.1534/genetics.107.078360
) / Genetics by L Menut (2007) -
Brown, S., Hu, N. & Hombria, J.C. Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless. Curr. Biol. 11, 1700–1705 (2001).
(
10.1016/S0960-9822(01)00524-3
) / Curr. Biol. by S Brown (2001) -
Callus, B.A. & Mathey-Prevot, B. SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing disc. Oncogene 21, 4812–4821 (2002).
(
10.1038/sj.onc.1205618
) / Oncogene by BA Callus (2002) -
Sparmann, A. & van Lohuizen, M. Polycomb silencers control cell fate, development and cancer. Nat. Rev. Cancer 6, 846–856 (2006).
(
10.1038/nrc1991
) / Nat. Rev. Cancer by A Sparmann (2006) -
Pietersen, A.M. & van Lohuizen, M. Stem cell regulation by polycomb repressors: postponing commitment. Curr. Opin. Cell Biol. 20, 201–207 (2008).
(
10.1016/j.ceb.2008.01.004
) / Curr. Opin. Cell Biol. by AM Pietersen (2008) -
Calás, C. et al. Inactivation of the polycomb group protein Ring1B unveils an antiproliferative role in hematopoietic cell expansion and cooperation with tumorigenesis associated with Ink4a deletion. Mol. Cell. Biol. 28, 1018–1028 (2008).
(
10.1128/MCB.01136-07
) / Mol. Cell. Biol. by C Calás (2008) -
Kanno, M., Hasegawa, M., Ishida, A., Isono, K. & Taniguchi, M. mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity. EMBO J. 14, 5672–5678 (1995).
(
10.1002/j.1460-2075.1995.tb00254.x
) / EMBO J. by M Kanno (1995) -
Majewski, I.J. et al. Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity. PLoS Biol. 6, e93 (2008).
(
10.1371/journal.pbio.0060093
) / PLoS Biol. by IJ Majewski (2008) -
McClure, K.D. & Schubiger, G. Transdetermination: Drosophila imaginal disc cells exhibit stem cell-like potency. Int. J. Biochem. Cell Biol. 39, 1105–1118 (2007).
(
10.1016/j.biocel.2007.01.007
) / Int. J. Biochem. Cell Biol. by KD McClure (2007) -
Dreesen, O. & Brivanlou, A.H. Signaling pathways in cancer and embryonic stem cells. Stem Cell Rev. 3, 7–17 (2007).
(
10.1007/s12015-007-0004-8
) / Stem Cell Rev. by O Dreesen (2007) -
Arbouzova, N.I. & Zeidler, M.P. JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions. Development 133, 2605–2616 (2006).
(
10.1242/dev.02411
) / Development by NI Arbouzova (2006) -
Chang, S. & Aune, T.M. Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells. Nat. Immunol. 8, 723–731 (2007).
(
10.1038/ni1473
) / Nat. Immunol. by S Chang (2007) -
Koyanagi, M. et al. EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells. J. Biol. Chem. 280, 31470–31477 (2005).
(
10.1074/jbc.M504766200
) / J. Biol. Chem. by M Koyanagi (2005) -
Mukherjee, T., Hombria, J.C. & Zeidler, M.P. Opposing roles for Drosophila JAK/STAT signalling during cellular proliferation. Oncogene 24, 2503–2511 (2005).
(
10.1038/sj.onc.1208487
) / Oncogene by T Mukherjee (2005) -
Coelho, C.M. et al. Growth and cell survival are unevenly impaired in pixie mutant wing discs. Development 132, 5411–5424 (2005).
(
10.1242/dev.02148
) / Development by CM Coelho (2005) -
Klebes, A. et al. Regulation of cellular plasticity in Drosophila imaginal disc cells by the Polycomb group, trithorax group and lama genes. Development 132, 3753–3765 (2005).
(
10.1242/dev.01927
) / Development by A Klebes (2005) -
Lee, N., Maurange, C., Ringrose, L. & Paro, R. Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs. Nature 438, 234–237 (2005).
(
10.1038/nature04120
) / Nature by N Lee (2005) -
McClure, K.D. & Schubiger, G. A screen for genes that function in leg disc regeneration in Drosophila melanogaster. Mech. Dev. 125, 67–80 (2008).
(
10.1016/j.mod.2007.10.003
) / Mech. Dev. by KD McClure (2008) -
Parrish, J.Z., Emoto, K., Jan, L.Y. & Jan, Y.N. Polycomb genes interact with the tumor suppressor genes hippo and warts in the maintenance of Drosophila sensory neuron dendrites. Genes Dev. 21, 956–972 (2007).
(
10.1101/gad.1514507
) / Genes Dev. by JZ Parrish (2007) -
Tapon, N., Ito, N., Dickson, B.J., Treisman, J.E. & Hariharan, I.K. The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell 105, 345–355 (2001).
(
10.1016/S0092-8674(01)00332-4
) / Cell by N Tapon (2001) -
Peng, J.C. & Karpen, G.H. H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability. Nat. Cell Biol. 9, 25–35 (2007).
(
10.1038/ncb1514
) / Nat. Cell Biol. by JC Peng (2007) -
Strutt, H., Cavalli, G. & Paro, R. Co-localization of Polycomb protein and GAGA factor on regulatory elements responsible for the maintenance of homeotic gene expression. EMBO J. 16, 3621–3632 (1997).
(
10.1093/emboj/16.12.3621
) / EMBO J. by H Strutt (1997)
Dates
Type | When |
---|---|
Created | 15 years, 11 months ago (Sept. 13, 2009, 1:54 p.m.) |
Deposited | 2 years, 3 months ago (May 18, 2023, 4:09 p.m.) |
Indexed | 1 week, 3 days ago (Aug. 20, 2025, 8:57 a.m.) |
Issued | 15 years, 11 months ago (Sept. 13, 2009) |
Published | 15 years, 11 months ago (Sept. 13, 2009) |
Published Online | 15 years, 11 months ago (Sept. 13, 2009) |
Published Print | 15 years, 10 months ago (Oct. 1, 2009) |
@article{Classen_2009, title={A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling}, volume={41}, ISSN={1546-1718}, url={http://dx.doi.org/10.1038/ng.445}, DOI={10.1038/ng.445}, number={10}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Classen, Anne-Kathrin and Bunker, Brandon D and Harvey, Kieran F and Vaccari, Thomas and Bilder, David}, year={2009}, month=sep, pages={1150–1155} }