Crossref
journal-article
Springer Science and Business Media LLC
Nature Cell Biology (297)
References
30
Referenced
347
-
Hollstein, M., Sidransky, D., Vogelstein, B. & Harris, C. C. p53 mutations in human cancers. Science 253, 49–53 (1991).
(
10.1126/science.1905840
) / Science by M Hollstein (1991) - Sigal, A. & Rotter, V. Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res. 60, 6788–6793 (2000). / Cancer Res. by A Sigal (2000)
-
Gudkov, A. Microarray analysis of p53-mediated transcription: multi-thousand piece puzzle or invitation to collective thinking. Cancer Biol. Ther. 2, 444–445 (2003).
(
10.4161/cbt.2.4.480
) / Cancer Biol. Ther. by A Gudkov (2003) -
Murphy, M. E. The thousand doors that lead to death: p53-dependent repression and apoptosis. Cancer Biol. Ther. 2, 381–382 (2003).
(
10.4161/cbt.2.4.439
) / Cancer Biol. Ther. by ME Murphy (2003) -
Lin, T. et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nature Cell Biol. 7, 165–171 (2005).
(
10.1038/ncb1211
) / Nature Cell Biol. by T Lin (2005) -
Xu, Y. A new role for p53 in maintaining genetic stability in embryonic stem cells, Cell Cycle 4, 363–364 (2005).
(
10.4161/cc.4.3.1529
) / Cell Cycle by Y Xu (2005) -
Hainaut, P. & Hollstein, M. p53 and human cancer: the first ten thousand mutations. Adv. Cancer Res. 77, 81–137 (2000).
(
10.1016/S0065-230X(08)60785-X
) / Adv. Cancer Res. by P Hainaut (2000) -
Luo, J. L. et al. Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool. Oncogene 20, 320–328 (2001).
(
10.1038/sj.onc.1204080
) / Oncogene by JL Luo (2001) -
Feng, L., Hollstein, M. & Xu, Y. Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence. Cell Cycle 5, 2812–2819 (2006).
(
10.4161/cc.5.23.3526
) / Cell Cycle by L Feng (2006) -
Hergenhahn, M., Luo, J. L. & Hollstein, M. p53 designer genes for the modern mouse. Cell Cycle 3, 738–741 (2004).
(
10.4161/cc.3.6.890
) / Cell Cycle by M Hergenhahn (2004) -
Ben-Porath, I. & Weinberg, R. A. The signals and pathways activating cellular senescence, Int. J. Biochem. Cell Biol. 37, 961–976 (2005).
(
10.1016/j.biocel.2004.10.013
) / Biochem. Cell Biol. by I Ben-Porath (2005) -
Olive, K. P. et al. Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell 119, 847–860 (2004).
(
10.1016/j.cell.2004.11.004
) / Cell by KP Olive (2004) -
Liao, M. J. et al. No requirement for V(D)J recombination in p53-deficient thymic lymphoma. Mol Cell Biol 18, 3495–3501 (1998).
(
10.1128/MCB.18.6.3495
) / Mol Cell Biol by MJ Liao (1998) -
Bassing, C. H. et al. Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors. Cell 114, 359–370 (2003).
(
10.1016/S0092-8674(03)00566-X
) / Cell by CH Bassing (2003) - Lista, F., Bertness, V., Guidos, C. J., Danska, J. S. & Kirsch, I. R. The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: a severe combined immune deficiency (SCID) murine model. Cancer Res. 57, 4408–4413 (1997). / Cancer Res. by F Lista (1997)
-
Kang, J., Bronson, R. T. & Xu, Y. Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair. EMBO J. 21, 1447–1455 (2002).
(
10.1093/emboj/21.6.1447
) / EMBO J. by J Kang (2002) -
Shiloh, Y. ATM and related protein kinases: safeguarding genome integrity. Nature Rev. Cancer 3, 155–168 (2003).
(
10.1038/nrc1011
) / Nature Rev. Cancer by Y Shiloh (2003) -
Xu, Y. et al. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes Dev. 10, 2411–2422 (1996).
(
10.1101/gad.10.19.2411
) / Genes Dev. by Y Xu (1996) -
Barlow, C. et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 86, 159–171 (1996).
(
10.1016/S0092-8674(00)80086-0
) / Cell by C Barlow (1996) -
Bakkenist, C. J. & Kastan, M. B. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421, 499–506 (2003).
(
10.1038/nature01368
) / Nature by CJ Bakkenist (2003) -
Xu, Y. DNA damage: a trigger of innate immunity but a requirement for adaptive immune homeostasis. Nature Rev. Immunol. 24, 261–270 (2006).
(
10.1038/nri1804
) / Nature Rev. Immunol. by Y Xu (2006) -
Fernandez-Capetillo, O. et al. DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1. Nature Cell Biol. 4, 993–997 (2002).
(
10.1038/ncb884
) / Nature Cell Biol. by O Fernandez-Capetillo (2002) -
Kang, J. et al. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression. Mol. Cell Biol. 25, 661–670 (2005).
(
10.1128/MCB.25.2.661-670.2005
) / Mol. Cell Biol. by J Kang (2005) -
Falck, J., Coates, J. & Jackson, S. P. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature 434, 605–611 (2005).
(
10.1038/nature03442
) / Nature by J Falck (2005) -
You, Z., Chahwan, C., Bailis, J., Hunter, T. & Russell, P. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol. Cell Biol. 25, 5363–5379 (2005).
(
10.1128/MCB.25.13.5363-5379.2005
) / Mol. Cell Biol. by Z You (2005) -
Lee, J. H. & Paull, T. T. ATM activation by DNA double-strand breaks through the Mre11–Rad50–Nbs1 complex. Science 308, 551–554 (2005).
(
10.1126/science.1108297
) / Science by JH Lee (2005) -
Gaiddon, C., Lokshin, M., Ahn, J., Zhang, T. & Prives, C. A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Mol. Cell Biol. 21, 1874–1887 (2001).
(
10.1128/MCB.21.5.1874-1887.2001
) / Mol. Cell Biol. by C Gaiddon (2001) -
Lang, G. A. et al. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell 119, 861–872 (2004).
(
10.1016/j.cell.2004.11.006
) / Cell by GA Lang (2004) -
Assenmacher, N. & Hopfner, K. P. MRE11/RAD50/NBS1: complex activities. Chromosoma 113, 157–166 (2004).
(
10.1007/s00412-004-0306-4
) / Chromosoma by N Assenmacher (2004) -
Chao, C. et al. Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses. J. Biol. Chem. 278, 41028–41033 (2003).
(
10.1074/jbc.M306938200
) / J. Biol. Chem. by C Chao (2003)
Dates
Type | When |
---|---|
Created | 18 years, 4 months ago (April 8, 2007, 1:03 p.m.) |
Deposited | 2 years, 3 months ago (May 18, 2023, 3:29 p.m.) |
Indexed | 1 month, 2 weeks ago (July 16, 2025, 9:47 a.m.) |
Issued | 18 years, 4 months ago (April 8, 2007) |
Published | 18 years, 4 months ago (April 8, 2007) |
Published Online | 18 years, 4 months ago (April 8, 2007) |
Published Print | 18 years, 4 months ago (May 1, 2007) |
@article{Song_2007, title={p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM}, volume={9}, ISSN={1476-4679}, url={http://dx.doi.org/10.1038/ncb1571}, DOI={10.1038/ncb1571}, number={5}, journal={Nature Cell Biology}, publisher={Springer Science and Business Media LLC}, author={Song, Hoseok and Hollstein, Monica and Xu, Yang}, year={2007}, month=apr, pages={573–580} }