Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation
10.1038/ncb1301
Crossref journal-article
Springer Science and Business Media LLC
Nature Cell Biology (297)
Bibliography

Wu, J.-T., Lin, H.-C., Hu, Y.-C., & Chien, C.-T. (2005). Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation. Nature Cell Biology, 7(10), 1014–1020.

Authors 4
  1. June-Tai Wu (first)
  2. Hsiu-Chen Lin (additional)
  3. Yen-Chen Hu (additional)
  4. Cheng-Ting Chien (additional)
References 30 Referenced 143
  1. Ou, C. Y., Lin, Y. F., Chen, Y. J. & Chien, C. T. Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development. Genes Dev. 16, 2403–2414 (2002). (10.1101/gad.1011402) / Genes Dev. by CY Ou (2002)
  2. Pintard, L. et al. Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans. Curr. Biol. 13, 911–921 (2003). (10.1016/S0960-9822(03)00336-1) / Curr. Biol. by L Pintard (2003)
  3. Lyapina, S. et al. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science 292, 1382–1385 (2001). (10.1126/science.1059780) / Science by S Lyapina (2001)
  4. Zhou, C. et al. The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p. BMC Biochem. 2, 7 (2001). (10.1186/1471-2091-2-7) / BMC Biochem. by C Zhou (2001)
  5. Petroski, M. D. & Deshaies, R. J. Function and regulation of cullin-RING ubiquitin ligases. Nature Rev. Mol. Cell Biol. 6, 9–20 (2005). (10.1038/nrm1547) / Nature Rev. Mol. Cell Biol. by MD Petroski (2005)
  6. Willems, A. R., Schwab, M. & Tyers, M. A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin. Biochim. Biophys. Acta 1695, 133–170 (2004). (10.1016/j.bbamcr.2004.09.027) / Biochim. Biophys. Acta by AR Willems (2004)
  7. Kamura, T., Conrad, M. N., Yan, Q., Conaway, R. C. & Conaway, J. W. The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2. Genes Dev. 13, 2928–2933 (1999). (10.1101/gad.13.22.2928) / Genes Dev. by T Kamura (1999)
  8. Hori, T. et al. Covalent modification of all members of human cullin family proteins by NEDD8. Oncogene 18, 6829–6834 (1999). (10.1038/sj.onc.1203093) / Oncogene by T Hori (1999)
  9. Pan, Z. Q., Kentsis, A., Dias, D. C., Yamoah, K. & Wu, K. Nedd8 on cullin: building an expressway to protein destruction. Oncogene 23, 1985–1997 (2004). (10.1038/sj.onc.1207414) / Oncogene by ZQ Pan (2004)
  10. Wu, K., Chen, A. & Pan, Z. Q. Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization. J. Biol. Chem. 275, 32317–32324 (2000). (10.1074/jbc.M004847200) / J. Biol. Chem. by K Wu (2000)
  11. Kawakami, T. et al. NEDD8 recruits E2-ubiquitin to SCF E3 ligase. EMBO J. 20, 4003–4012 (2001). (10.1093/emboj/20.15.4003) / EMBO J. by T Kawakami (2001)
  12. Pintard, L. et al. The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase. Nature 425, 311–316 (2003). (10.1038/nature01959) / Nature by L Pintard (2003)
  13. Geyer, R., Wee, S., Anderson, S., Yates, J. & Wolf, D. A. BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases. Mol. Cell 12, 783–790 (2003). (10.1016/S1097-2765(03)00341-1) / Mol. Cell by R Geyer (2003)
  14. Wei, N. & Deng, X. W. The COP9 signalosome. Annu. Rev. Cell Dev. Biol. 19, 261–286 (2003). (10.1146/annurev.cellbio.19.111301.112449) / Annu. Rev. Cell Dev. Biol. by N Wei (2003)
  15. Cope, G. A. et al. Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298, 608–611 (2002). (10.1126/science.1075901) / Science by GA Cope (2002)
  16. Gusmaroli, G., Feng, S. & Deng, X. W. The Arabidopsis CSN5A and CSN5B subunits are present in distinct COP9 signalosome complexes, and mutations in their JAMM domains exhibit differential dominant negative effects on development. Plant Cell 16, 2984–3001 (2004). (10.1105/tpc.104.025999) / Plant Cell by G Gusmaroli (2004)
  17. Dohmann, E. M., Kuhnle, C. & Schwechheimer, C. Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 signalosome subunit 5 is sufficient to cause the cop/det/fus mutant phenotype in Arabidopsis. Plant Cell 17, 1967–1978 (2005). (10.1105/tpc.105.032870) / Plant Cell by EM Dohmann (2005)
  18. Doronkin, S., Djagaeva, I. & Beckendorf, S. K. The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis. Dev. Cell 4, 699–710 (2003). (10.1016/S1534-5807(03)00121-7) / Dev. Cell by S Doronkin (2003)
  19. Wee, S., Geyer, R. K., Toda, T. & Wolf, D. A. CSN facilitates Cullin–RING ubiquitin ligase function by counteracting autocatalytic adapter instability. Nature Cell Biol. 7, 387–391 (2005). (10.1038/ncb1241) / Nature Cell Biol. by S Wee (2005)
  20. Cope, G. A. & Deshaies, R. J. COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114, 663–671 (2003). (10.1016/S0092-8674(03)00722-0) / Cell by GA Cope (2003)
  21. Wolf, D. A., Zhou, C. & Wee, S. The COP9 signalosome: an assembly and maintenance platform for cullin ubiquitin ligases? Nature Cell Biol. 5, 1029–1033 (2003). (10.1038/ncb1203-1029) / Nature Cell Biol. by DA Wolf (2003)
  22. von Arnim, A. G. On again-off again: COP9 signalosome turns the key on protein degradation. Curr. Opin. Plant Biol. 6, 520–529 (2003). (10.1016/j.pbi.2003.09.006) / Curr. Opin. Plant Biol. by AG von Arnim (2003)
  23. Oron, E. et al. COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. Development 129, 4399–4409 (2002). (10.1242/dev.129.19.4399) / Development by E Oron (2002)
  24. Uhle, S. et al. Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome. EMBO J. 22, 1302–1312 (2003). (10.1093/emboj/cdg127) / EMBO J. by S Uhle (2003)
  25. Zhou, C. et al. Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p. Mol. Cell 11, 927–938 (2003). (10.1016/S1097-2765(03)00136-9) / Mol. Cell by C Zhou (2003)
  26. Groisman, R. et al. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. Cell 113, 357–367 (2003). (10.1016/S0092-8674(03)00316-7) / Cell by R Groisman (2003)
  27. He, Q., Cheng, P. & Liu, Y. The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex. Genes Dev. 19, 1518–1531 (2005). (10.1101/gad.1322205) / Genes Dev. by Q He (2005)
  28. Doronkin, S., Djagaeva, I. & Beckendorf, S. K. CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint. Development 129, 5053–5064 (2002). (10.1242/dev.129.21.5053) / Development by S Doronkin (2002)
  29. Worby, C. A., Simonson-Leff, N. & Dixon, J. E. RNA interference of gene expression (RNAi) in cultured Drosophila cells. Sci. STKE 2001, pl1 (2001). (10.1126/stke.2001.95.pl1) / Sci. STKE by CA Worby (2001)
  30. Chen, C. K. & Chien, C. T. Negative regulation of atonal in proneural cluster formation of Drosophila R8 photoreceptors. Proc. Natl Acad. Sci. USA 96, 5055–5060 (1999). (10.1073/pnas.96.9.5055) / Proc. Natl Acad. Sci. USA by CK Chen (1999)
Dates
Type When
Created 20 years ago (Aug. 26, 2005, 11:30 a.m.)
Deposited 1 year, 7 months ago (Jan. 29, 2024, 3:43 a.m.)
Indexed 1 week, 2 days ago (Aug. 28, 2025, 8:01 a.m.)
Issued 20 years ago (Aug. 28, 2005)
Published 20 years ago (Aug. 28, 2005)
Published Online 20 years ago (Aug. 28, 2005)
Published Print 19 years, 11 months ago (Oct. 1, 2005)
Funders 0

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@article{Wu_2005, title={Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation}, volume={7}, ISSN={1476-4679}, url={http://dx.doi.org/10.1038/ncb1301}, DOI={10.1038/ncb1301}, number={10}, journal={Nature Cell Biology}, publisher={Springer Science and Business Media LLC}, author={Wu, June-Tai and Lin, Hsiu-Chen and Hu, Yen-Chen and Chien, Cheng-Ting}, year={2005}, month=aug, pages={1014–1020} }