DOI: 10.1038/ncb1218. TRPC1 forms the stretch-activated cation channel in vertebrate cells

TRPC1 forms the stretch-activated cation channel in vertebrate cells

10.1038/ncb1218

Crossref journal-article

Springer Science and Business Media LLC

Nature Cell Biology (297)

Bibliography

Maroto, R., Raso, A., Wood, T. G., Kurosky, A., Martinac, B., & Hamill, O. P. (2005). TRPC1 forms the stretch-activated cation channel in vertebrate cells. Nature Cell Biology, 7(2), 179â185.

Authors 6

Rosario Maroto (first)
Albert Raso (additional)
Thomas G. Wood (additional)
Alex Kurosky (additional)
Boris Martinac (additional)
Owen P. Hamill (additional)

References 30 Referenced 557

Christensen, O. Mediation of cell volume regulation by Ca2+ influx through stretch-activated channels. Nature 330, 66–68 (1987). (10.1038/330066a0) / Nature by O Christensen (1987)
Lee, J., Ishihara, A., Oxford, G., Johnson, B. & Jacobson, K. Regulation of cell movement is mediated by stretch-activated calcium channels. Nature 400, 382–386 (1999). (10.1038/22578) / Nature by J Lee (1999)
Obregón-Franco, A. & Lansman, J. B. Changes in mechanosensitive channel gating following mechanical stimulation in skeletal muscle myotubes from the mdx mouse. J. Physiol. 539, 391–407 (2002). (10.1113/jphysiol.2001.013043) / J. Physiol. by A Obregón-Franco (2002)
Bode, F., Sachs, F. & Franz, M. R. Tarantula peptide inhibits atrial fibrillation. Nature 409, 35–36 (2001). (10.1038/35051165) / Nature by F Bode (2001)
Sukharev, S. I., Martinac, B., Arshavsky, V. Y. & Kung, C. Two types of mechanosensitive channels in the Escherichia coli cell envelope: solubilization and functional reconstitution. Biophys. J. 65, 177–183 (1993). (10.1016/S0006-3495(93)81044-0) / Biophys. J. by SI Sukharev (1993)
Zhang, Y. & Hamill, O. P. Calcium-, voltage- and osmotic-stress sensitive currents in Xenopus oocytes and their relationship to single mechanically-gated channels. J. Physiol. 523, 83–99 (2000). (10.1111/j.1469-7793.2000.t01-2-00083.x) / J. Physiol. by Y Zhang (2000)
Zhang, Y., Gao, F., Popov, V. L., Wen, J. W. & Hamill, O. P. Mechanically- gated channel activity in cytoskeleton-deficient plasma membrane blebs and vesicles from Xenopus oocytes. J. Physiol. 523, 117–130 (2000). (10.1111/j.1469-7793.2000.t01-1-00117.x) / J. Physiol. by Y Zhang (2000)
Wes, P. D. et al. TRPC1, a human homolog of a Drosophila store operated channel. Proc. Natl Acad. Sci. USA 92, 9652–9656 (1995). (10.1073/pnas.92.21.9652) / Proc. Natl Acad. Sci. USA by PD Wes (1995)
Bobanovic, L. K. et al. Molecular cloning and immunolocalization of a novel vertebrate TRP homologue from Xenopus. Biochemistry 340, 593–599 (1999). (10.1042/bj3400593) / Biochemistry by LK Bobanovic (1999)
Brereton, H. M., Harland, M. L., Auld, A. M. & Barritt, G. J. Evidence that the TRP-1 protein is unlikely to account for store-operated Ca2+ inflow in Xenopus laevis oocytes. Mol. Cell. Biochem. 214, 63–74 (2000). (10.1023/A:1007193720930) / Mol. Cell. Biochem. by HM Brereton (2000)
Martinac, B. & Kloda, A. Evolutionary origins of mechanosensitive ion channels. Prog. Biophys. Mol. Biol. 82, 11–24 (2003). (10.1016/S0079-6107(03)00002-6) / Prog. Biophys. Mol. Biol. by B Martinac (2003)
Taglietti, V. & Toselli, M. A study of stretch-activated channels in the membrane of frog oocytes: interactions with Ca2+ ions. J. Physiol. 407, 311–328 (1988). (10.1113/jphysiol.1988.sp017417) / J. Physiol. by V Taglietti (1988)
Yang, X. C. & Sachs, F. Characterization of stretch-activated ion channels in Xenopus oocytes. J. Physiol. 431, 103–122 (1990). (10.1113/jphysiol.1990.sp018322) / J. Physiol. by XC Yang (1990)
Wu, G., McBride, D. W. & Hamill, O. P. Mg2+ block and inward rectification of mechanosensitive channel in Xenopus oocytes. Pflügers Achiv. 435, 572–574 (1998). (10.1007/s004240050554) / Pflügers Achiv. by G Wu (1998)
Minke, B. & Cook, B. TRP channel proteins and signal transduction. Physiol. Rev. 82, 429–472 (2002). (10.1152/physrev.00001.2002) / Physiol. Rev. by B Minke (2002)
Wilkinson, N. C., Gao, F. & Hamill, O. P. Effects of mechano-gated cation channel blockers on Xenopus oocyte growth and development. J. Membr. Biol. 165, 161–174 (1998). (10.1007/s002329900430) / J. Membr. Biol. by NC Wilkinson (1998)
Riccio, A. et al. mRNA distribution analysis of human TRPC family in CNS and peripheral tissues. Mol. Brain Res. 109, 95–104 (2002). (10.1016/S0169-328X(02)00527-2) / Mol. Brain Res. by A Riccio (2002)
Zitt, C. et al. Cloning and functional expression of a human Ca2+-permeable cation channel activated by calcium store depletion. Neuron 16, 1189–1196 (1996). (10.1016/S0896-6273(00)80145-2) / Neuron by C Zitt (1996)
Lockwich, T. P. et al. Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains. J. Biol. Chem. 275, 11934–11942 (2000). (10.1074/jbc.275.16.11934) / J. Biol. Chem. by TP Lockwich (2000)
Sinkins, W. G., Estacion, M. & Schilling, W. P. Functional expression of TRPC1: a human homologue of the Drosophila TRP channel. Biochem. J. 331, 331–339 (1998). (10.1042/bj3310331) / Biochem. J. by WG Sinkins (1998)
Lintschinger, B. et al. Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels. J. Biol. Chem. 275, 27799–27805 (2000). (10.1074/jbc.M002705200) / J. Biol. Chem. by B Lintschinger (2000)
Brereton, H. M., Chen, J., Rychkov, G., Harland, M. L. & Barritt, G. J. Maitotoxin activates an endogenous non-selective cation channel and is an effective initiator of the activation of the heterologously expressed hTRPC-1 (transient receptor potential) non-selective cation channel in H4-IIE liver cells. Biochim. Biophys. Acta 1540, 107–126 (2001). (10.1016/S0167-4889(01)00124-0) / Biochim. Biophys. Acta by HM Brereton (2001)
Clapham, D. E. TRP channels as cellular sensors. Nature 426, 517–524 (2003). (10.1038/nature02196) / Nature by DE Clapham (2003)
Vandebrouck, C., Martin, D., Colson-Van Schoor, M., Debaix, H. & Gailly, P. Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers. J. Cell Biol. 158, 1089–1096 (2002). (10.1083/jcb.200203091) / J. Cell Biol. by C Vandebrouck (2002)
Hofmann, T., Schaeffer, M. Schultz, G. & Gudermann, T. Subunit composition of mammalian transient receptor potential channels in living cells. Proc. Natl Acad. Sci. USA 99, 7461–7466 (2002). (10.1073/pnas.102596199) / Proc. Natl Acad. Sci. USA by T Hofmann (2002)
Tsiokas, L. et al. Specific association of the gene product of pkD2 with the TRPC1 channel. Proc. Natl Acad. Sci. USA 96, 3934–3939 (1999). (10.1073/pnas.96.7.3934) / Proc. Natl Acad. Sci. USA by L Tsiokas (1999)
Hamill, O. P. & Martinac, B. Molecular basis of mechanotransduction in living cells. Physiol. Rev. 81, 685–740 (2001). (10.1152/physrev.2001.81.2.685) / Physiol. Rev. by OP Hamill (2001)
Wall, D. A. & Patel, S. Isolation of plasma membrane complexes from Xenopus oocytes. J. Membr. Biol. 107, 189–201 (1989). (10.1007/BF01871724) / J. Membr. Biol. by DA Wall (1989)
Jespersen, T., Grunnet, M., Angelo, K., Klærke, D. A. & Olesen, S. P. Dual function vector for protein expression in both mammalian cells and Xenopus laevis oocytes. Biotechniques 32, 536–540 (2002). (10.2144/02323st05) / Biotechniques by T Jespersen (2002)
McBride, D. W. Jr & Hamill, O. P. Pressure-clamp: a method for rapid step perturbation of mechanosensitive channels. Pflügers Archiv. 421, 606–612 (1992). (10.1007/BF00375058) / Pflügers Archiv. by DW McBride Jr (1992)

Dates

Type	When
Created	20 years, 7 months ago (Jan. 24, 2005, 5:31 a.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 3:26 p.m.)
Indexed	3 weeks, 4 days ago (Aug. 2, 2025, 1:17 a.m.)
Issued	20 years, 7 months ago (Jan. 23, 2005)
Published	20 years, 7 months ago (Jan. 23, 2005)
Published Online	20 years, 7 months ago (Jan. 23, 2005)
Published Print	20 years, 6 months ago (Feb. 1, 2005)

Funders 0

None

BibTeX

@article{Maroto_2005, title={TRPC1 forms the stretch-activated cation channel in vertebrate cells}, volume={7}, ISSN={1476-4679}, url={http://dx.doi.org/10.1038/ncb1218}, DOI={10.1038/ncb1218}, number={2}, journal={Nature Cell Biology}, publisher={Springer Science and Business Media LLC}, author={Maroto, Rosario and Raso, Albert and Wood, Thomas G. and Kurosky, Alex and Martinac, Boris and Hamill, Owen P.}, year={2005}, month=jan, pages={179–185} }

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