RNA interference screen for human genes associated with West Nile virus infection
10.1038/nature07207
Crossref journal-article
Springer Science and Business Media LLC
Nature (297)
Bibliography

Krishnan, M. N., Ng, A., Sukumaran, B., Gilfoy, F. D., Uchil, P. D., Sultana, H., Brass, A. L., Adametz, R., Tsui, M., Qian, F., Montgomery, R. R., Lev, S., Mason, P. W., Koski, R. A., Elledge, S. J., Xavier, R. J., Agaisse, H., & Fikrig, E. (2008). RNA interference screen for human genes associated with West Nile virus infection. Nature, 455(7210), 242–245.

Authors 18
  1. Manoj N. Krishnan (first)
  2. Aylwin Ng (additional)
  3. Bindu Sukumaran (additional)
  4. Felicia D. Gilfoy (additional)
  5. Pradeep D. Uchil (additional)
  6. Hameeda Sultana (additional)
  7. Abraham L. Brass (additional)
  8. Rachel Adametz (additional)
  9. Melody Tsui (additional)
  10. Feng Qian (additional)
  11. Ruth R. Montgomery (additional)
  12. Sima Lev (additional)
  13. Peter W. Mason (additional)
  14. Raymond A. Koski (additional)
  15. Stephen J. Elledge (additional)
  16. Ramnik J. Xavier (additional)
  17. Herve Agaisse (additional)
  18. Erol Fikrig (additional)
References 34 Referenced 456
  1. Brinton, M. A. The molecular biology of West Nile Virus: A new invader of the western hemisphere. Annu. Rev. Microbiol. 56, 371–402 (2002) (10.1146/annurev.micro.56.012302.160654) / Annu. Rev. Microbiol. by MA Brinton (2002)
  2. Chu, J. J. & Ng, M. L. Infectious entry of West Nile virus occurs through a clathrin-mediated endocytic pathway. J. Virol. 78, 10543–10555 (2004) (10.1128/JVI.78.19.10543-10555.2004) / J. Virol. by JJ Chu (2004)
  3. Krishnan, M. N. et al. Rab 5 is required for the cellular entry of dengue and West Nile viruses. J. Virol. 81, 4881–4885 (2007) (10.1128/JVI.02210-06) / J. Virol. by MN Krishnan (2007)
  4. Brass, A. L. et al. Identification of host proteins required for HIV infection through a functional genomic screen. Science 319, 921–926 (2008) (10.1126/science.1152725) / Science by AL Brass (2008)
  5. Ng, T. I. et al. Identification of host genes involved in hepatitis C virus replication by small interfering RNA technology. Hepatology 45, 1413–1421 (2007) (10.1002/hep.21608) / Hepatology by TI Ng (2007)
  6. Pelkmans, L. et al. Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis. Nature 436, 78–86 (2005) (10.1038/nature03571) / Nature by L Pelkmans (2005)
  7. Davis, W. G., Blackwell, J. L., Shi, P. Y. & Brinton, M. A. Interaction between the cellular protein eEF1A and the 3′-terminal stem-loop of West Nile virus genomic RNA facilitates viral minus-strand RNA synthesis. J. Virol. 81, 10172–10187 (2007) (10.1128/JVI.00531-07) / J. Virol. by WG Davis (2007)
  8. Emara, M. M. & Brinton, M. A. Interaction of TIA-1/TIAR with West Nile and dengue virus products in infected cells interferes with stress granule formation and processing body assembly. Proc. Natl Acad. Sci. USA 104, 9041–9046 (2007) (10.1073/pnas.0703348104) / Proc. Natl Acad. Sci. USA by MM Emara (2007)
  9. Hirsch, A. J. et al. The Src family kinase c-Yes is required for maturation of West Nile virus particles. J. Virol. 79, 11943–11951 (2005) (10.1128/JVI.79.18.11943-11951.2005) / J. Virol. by AJ Hirsch (2005)
  10. Mackenzie, J. M., Khromykh, A. A. & Parton, R. G. Cholesterol manipulation by West Nile virus perturbs the cellular immune response. Cell Host Microbe 2, 229–239 (2007) (10.1016/j.chom.2007.09.003) / Cell Host Microbe by JM Mackenzie (2007)
  11. Fredericksen, B. L., Smith, M., Katze, M. G., Shi, P. Y. & Gale, M. The host response to West Nile Virus infection limits viral spread through the activation of the interferon regulatory factor 3 pathway. J. Virol. 78, 7737–7747 (2004) (10.1128/JVI.78.14.7737-7747.2004) / J. Virol. by BL Fredericksen (2004)
  12. Lim, J. et al. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Cell 125, 801–814 (2006) (10.1016/j.cell.2006.03.032) / Cell by J Lim (2006)
  13. Mashimo, T. et al. A nonsense mutation in the gene encoding 2′-5′-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice. Proc. Natl Acad. Sci. USA 99, 11311–11316 (2002) (10.1073/pnas.172195399) / Proc. Natl Acad. Sci. USA by T Mashimo (2002)
  14. Samuel, M. A. et al. PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons. J. Virol. 80, 7009–7019 (2006) (10.1128/JVI.00489-06) / J. Virol. by MA Samuel (2006)
  15. Scherbik, S. V., Paranjape, J. M., Stockman, B. M., Silverman, R. H. & Brinton, M. A. RNase L plays a role in the antiviral response to West Nile virus. J. Virol. 80, 2987–2999 (2006) (10.1128/JVI.80.6.2987-2999.2006) / J. Virol. by SV Scherbik (2006)
  16. Tecle, T., White, M. R., Gantz, D., Crouch, E. C. & Hartshorn, K. L. Human neutrophil defensins increase neutrophil uptake of influenza A virus and bacteria and modify virus-induced respiratory burst responses. J. Immunol. 178, 8046–8052 (2007) (10.4049/jimmunol.178.12.8046) / J. Immunol. by T Tecle (2007)
  17. Fujita, Y. et al. Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nature Cell Biol. 4, 222–231 (2002) (10.1038/ncb758) / Nature Cell Biol. by Y Fujita (2002)
  18. Dell'Angelica, E. C. et al. AP-3: An adaptor-like protein complex with ubiquitous expression. EMBO J. 16, 917–928 (1997) (10.1093/emboj/16.5.917) / EMBO J. by EC Dell'Angelica (1997)
  19. Khor, R., McElroy, L. J. & Whittaker, G. R. The ubiquitin-vacuolar protein sorting system is selectively required during entry of influenza virus into host cells. Traffic 4, 857–868 (2003) (10.1046/j.1398-9219.2003.0140.x) / Traffic by R Khor (2003)
  20. Meusser, B., Hirsch, C., Jarosch, E. & Sommer, T. ERAD: The long road to destruction. Nature Cell Biol. 7, 766–772 (2005) (10.1038/ncb0805-766) / Nature Cell Biol. by B Meusser (2005)
  21. Wakana, Y. et al. Bap31 is an itinerant protein that moves between the peripheral ER and a juxtanuclear compartment related to ER-associated degradation. Mol. Biol. Cell 19, 1825–1836 (2008) (10.1091/mbc.e07-08-0781) / Mol. Biol. Cell by Y Wakana (2008)
  22. Schelhaas, M. et al. Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells. Cell 131, 516–529 (2007) (10.1016/j.cell.2007.09.038) / Cell by M Schelhaas (2007)
  23. Halestrap, A. P. & Price, N. T. The proton-linked monocarboxylate transporter (MCT) family: Structure, function and regulation. Biochem. J. 343, 281–299 (1999) (10.1042/bj3430281) / Biochem. J. by AP Halestrap (1999)
  24. Chiu, M. W., Shih, H. M., Yang, T. H. & Yang, Y. L. The type 2 dengue virus envelope protein interacts with small ubiquitin-like modifier-1 (SUMO-1) conjugating enzyme 9 (Ubc9). J. Biomed. Sci. 14, 429–444 (2007) (10.1007/s11373-007-9151-9) / J. Biomed. Sci. by MW Chiu (2007)
  25. Hanks, S. K., Ryzhova, L., Shin, N. Y. & Brabek, J. Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility. Front. Biosci. 8, d982–d996 (2003) (10.2741/1114) / Front. Biosci. by SK Hanks (2003)
  26. Mi, H. et al. The PANTHER database of protein families, subfamilies, functions and pathways. Nucleic Acids Res. 33, D284–D288 (2005) (10.1093/nar/gki078) / Nucleic Acids Res. by H Mi (2005)
  27. Su, A. I. et al. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc. Natl Acad. Sci. USA 101, 6062–6067 (2004) (10.1073/pnas.0400782101) / Proc. Natl Acad. Sci. USA by AI Su (2004)
  28. Mishra, G. R. et al. Human protein reference database — 2006 update. Nucleic Acids Res. 34, D411–D414 (2006) (10.1093/nar/gkj141) / Nucleic Acids Res. by GR Mishra (2006)
  29. Bader, G. D., Betel, D. & Hogue, C. W. BIND: The Biomolecular Interaction Network Database. Nucleic Acids Res. 31, 248–250 (2003) (10.1093/nar/gkg056) / Nucleic Acids Res. by GD Bader (2003)
  30. Scholle, F. & Mason, P. W. West Nile virus replication interferes with both poly(I:C)-induced interferon gene transcription and response to interferon treatment. Virology 342, 77–87 (2005) (10.1016/j.virol.2005.07.021) / Virology by F Scholle (2005)
  31. Rossi, S. L., Zhao, Q., O'Donnell, V. K. & Mason, P. W. Adaptation of West Nile virus replicons to cells in culture and use of replicon-bearing cells to probe antiviral action. Virology 331, 457–470 (2005) (10.1016/j.virol.2004.10.046) / Virology by SL Rossi (2005)
  32. Helenius, A., Kartenbeck, J., Simons, K. & Fries, E. On the entry of Semliki forest virus into BHK-21 cells. J. Cell Biol. 84, 404–420 (1980) (10.1083/jcb.84.2.404) / J. Cell Biol. by A Helenius (1980)
  33. Eisen, M. B., Spellman, P. T., Brown, P. O. & Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl Acad. Sci. USA 95, 14863–14868 (1998) (10.1073/pnas.95.25.14863) / Proc. Natl Acad. Sci. USA by MB Eisen (1998)
  34. Saldanha, A. J. Java Treeview — extensible visualization of microarray data. Bioinformatics 20, 3246–3248 (2004) (10.1093/bioinformatics/bth349) / Bioinformatics by AJ Saldanha (2004)
Dates
Type When
Created 17 years ago (Aug. 8, 2008, 9:34 a.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 2:17 p.m.)
Indexed 1 month ago (July 23, 2025, 8:13 a.m.)
Issued 17 years ago (Aug. 6, 2008)
Published 17 years ago (Aug. 6, 2008)
Published Online 17 years ago (Aug. 6, 2008)
Published Print 16 years, 11 months ago (Sept. 1, 2008)
Funders 0

None

@article{Krishnan_2008, title={RNA interference screen for human genes associated with West Nile virus infection}, volume={455}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature07207}, DOI={10.1038/nature07207}, number={7210}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Krishnan, Manoj N. and Ng, Aylwin and Sukumaran, Bindu and Gilfoy, Felicia D. and Uchil, Pradeep D. and Sultana, Hameeda and Brass, Abraham L. and Adametz, Rachel and Tsui, Melody and Qian, Feng and Montgomery, Ruth R. and Lev, Sima and Mason, Peter W. and Koski, Raymond A. and Elledge, Stephen J. and Xavier, Ramnik J. and Agaisse, Herve and Fikrig, Erol}, year={2008}, month=aug, pages={242–245} }