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Bibliography

Bessonov, S., Anokhina, M., Will, C. L., Urlaub, H., & Lührmann, R. (2008). Isolation of an active step I spliceosome and composition of its RNP core. Nature, 452(7189), 846–850.

Authors 5
  1. Sergey Bessonov (first)
  2. Maria Anokhina (additional)
  3. Cindy L. Will (additional)
  4. Henning Urlaub (additional)
  5. Reinhard Lührmann (additional)
References 27 Referenced 315
  1. Will, C. L. & Lührmann, R. in The RNA World (eds Gesteland, R. F., Cech, T. R. & Atkins, J. F.) 369–400 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 2006) / The RNA World by CL Will (2006)
  2. Staley, J. P. & Guthrie, C. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92, 315–326 (1998) (10.1016/S0092-8674(00)80925-3) / Cell by JP Staley (1998)
  3. Nilsen, T. W. in RNA Structure and Function (eds Grundber-Manago, M. & Simsons, R. W.) 279–307 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1998) / RNA Structure and Function by TW Nilsen (1998)
  4. Umen, J. G. & Guthrie, C. The second catalytic step of pre-mRNA splicing. RNA 1, 869–885 (1995) / RNA by JG Umen (1995)
  5. Konarska, M. M., Vilardell, J. & Query, C. C. Repositioning of the reaction intermediate within the catalytic center of the spliceosome. Mol. Cell 21, 543–553 (2006) (10.1016/j.molcel.2006.01.017) / Mol. Cell by MM Konarska (2006)
  6. Valadkhan, S. & Manley, J. L. Splicing-related catalysis by protein-free snRNAs. Nature 413, 701–707 (2001) (10.1038/35099500) / Nature by S Valadkhan (2001)
  7. Will, C. L. & Lührmann, R. Protein functions in pre-mRNA splicing. Curr. Opin. Cell Biol. 9, 320–328 (1997) (10.1016/S0955-0674(97)80003-8) / Curr. Opin. Cell Biol. by CL Will (1997)
  8. Grainger, R. J. & Beggs, J. D. Prp8 protein: at the heart of the spliceosome. RNA 11, 533–557 (2005) (10.1261/rna.2220705) / RNA by RJ Grainger (2005)
  9. Tarn, W. Y., Lee, K. R. & Cheng, S. C. Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA. Proc. Natl Acad. Sci. USA 90, 10821–10825 (1993) (10.1073/pnas.90.22.10821) / Proc. Natl Acad. Sci. USA by WY Tarn (1993)
  10. Tarn, W. Y. et al. Functional association of essential splicing factor(s) with PRP19 in a protein complex. EMBO J. 13, 2421–2431 (1994) (10.1002/j.1460-2075.1994.tb06527.x) / EMBO J. by WY Tarn (1994)
  11. Ajuh, P. et al. Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. EMBO J. 19, 6569–6581 (2000) (10.1093/emboj/19.23.6569) / EMBO J. by P Ajuh (2000)
  12. Chan, S. P., Kao, D. I., Tsai, W. Y. & Cheng, S. C. The Prp19p-associated complex in spliceosome activation. Science 302, 279–282 (2003) (10.1126/science.1086602) / Science by SP Chan (2003)
  13. Makarova, O. V. et al. A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO J. 23, 2381–2391 (2004) (10.1038/sj.emboj.7600241) / EMBO J. by OV Makarova (2004)
  14. Gozani, O., Feld, R. & Reed, R. Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A. Genes Dev. 10, 233–243 (1996) (10.1101/gad.10.2.233) / Genes Dev. by O Gozani (1996)
  15. Will, C. L. et al. A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site. EMBO J. 20, 4536–4546 (2001) (10.1093/emboj/20.16.4536) / EMBO J. by CL Will (2001)
  16. Anderson, K. & Moore, M. J. Bimolecular exon ligation by the human spliceosome. Science 276, 1712–1716 (1997) (10.1126/science.276.5319.1712) / Science by K Anderson (1997)
  17. Anderson, K. & Moore, M. J. Bimolecular exon ligation by the human spliceosome bypasses early 3′ splice site AG recognition and requires NTP hydrolysis. RNA 6, 16–25 (2000) (10.1017/S1355838200001862) / RNA by K Anderson (2000)
  18. Deckert, J. et al. Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions. Mol. Cell. Biol. 26, 5528–5543 (2006) (10.1128/MCB.00582-06) / Mol. Cell. Biol. by J Deckert (2006)
  19. Achsel, T., Ahrens, K., Brahms, H., Teigelkamp, S. & Lührmann, R. The human U5–220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. Mol. Cell. Biol. 18, 6756–6766 (1998) (10.1128/MCB.18.11.6756) / Mol. Cell. Biol. by T Achsel (1998)
  20. Smith, D. J., Query, C. C. & Konarska, M. M. Trans-splicing to spliceosomal U2 snRNA suggests disruption of branch site-U2 pairing during pre-mRNA splicing. Mol. Cell 26, 883–890 (2007) (10.1016/j.molcel.2007.05.020) / Mol. Cell by DJ Smith (2007)
  21. Collins, C. A. & Guthrie, C. The question remains: is the spliceosome a ribozyme? Nature Struct. Biol. 7, 850–854 (2000) (10.1038/79598) / Nature Struct. Biol. by CA Collins (2000)
  22. Makarov, E. M. et al. Small nuclear ribonucleoprotein remodelling during catalytic activation of the spliceosome. Science 298, 2205–2208 (2002) (10.1126/science.1077783) / Science by EM Makarov (2002)
  23. Dignam, J. D., Lebovitz, R. M. & Roeder, R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11, 1475–1489 (1983) (10.1093/nar/11.5.1475) / Nucleic Acids Res. by JD Dignam (1983)
  24. Das, R. & Reed, R. Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels. RNA 5, 1504–1508 (1999) (10.1017/S1355838299991501) / RNA by R Das (1999)
  25. Hartmuth, K. et al. Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proc. Natl Acad. Sci. USA 99, 16719–16724 (2002) (10.1073/pnas.262483899) / Proc. Natl Acad. Sci. USA by K Hartmuth (2002)
  26. Wollerton, M. C., Gooding, C., Wagner, E. J., Garcia-Blanco, M. A. & Smith, C. W. Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay. Mol. Cell 13, 91–100 (2006) (10.1016/S1097-2765(03)00502-1) / Mol. Cell by MC Wollerton (2006)
  27. Dybkov, O. et al. U2 snRNA-protein contacts in purified human 17S U2 snRNPs and in spliceosomal A and B complexes. Mol. Cell. Biol. 26, 2803–2816 (2006) (10.1128/MCB.26.7.2803-2816.2006) / Mol. Cell. Biol. by O Dybkov (2006)
Dates
Type When
Created 17 years, 5 months ago (March 5, 2008, 5:01 p.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 2:14 p.m.)
Indexed 1 week, 6 days ago (Aug. 21, 2025, 1:03 p.m.)
Issued 17 years, 5 months ago (March 5, 2008)
Published 17 years, 5 months ago (March 5, 2008)
Published Online 17 years, 5 months ago (March 5, 2008)
Published Print 17 years, 5 months ago (April 1, 2008)
Funders 0

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@article{Bessonov_2008, title={Isolation of an active step I spliceosome and composition of its RNP core}, volume={452}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature06842}, DOI={10.1038/nature06842}, number={7189}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Bessonov, Sergey and Anokhina, Maria and Will, Cindy L. and Urlaub, Henning and Lührmann, Reinhard}, year={2008}, month=mar, pages={846–850} }