DOI: 10.1038/nature06403. Nanog safeguards pluripotency and mediates germline development

Nanog safeguards pluripotency and mediates germline development

10.1038/nature06403

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Chambers, I., Silva, J., Colby, D., Nichols, J., Nijmeijer, B., Robertson, M., Vrana, J., Jones, K., Grotewold, L., & Smith, A. (2007). Nanog safeguards pluripotency and mediates germline development. Nature, 450(7173), 1230â1234.

Authors 10

Ian Chambers (first)
Jose Silva (additional)
Douglas Colby (additional)
Jennifer Nichols (additional)
Bianca Nijmeijer (additional)
Morag Robertson (additional)
Jan Vrana (additional)
Ken Jones (additional)
Lars Grotewold (additional)
Austin Smith (additional)

References 34 Referenced 1,269

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Mitsui, K. et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113, 631–642 (2003) (10.1016/S0092-8674(03)00393-3) / Cell by K Mitsui (2003)
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Ivanova, N. et al. Dissecting self-renewal in stem cells with RNA interference. Nature 442, 533–538 (2006) (10.1038/nature04915) / Nature by N Ivanova (2006)
Ying, Q. L., Nichols, J., Chambers, I. & Smith, A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115, 281–292 (2003) (10.1016/S0092-8674(03)00847-X) / Cell by QL Ying (2003)
Hatano, S. Y. et al. Pluripotential competence of cells associated with Nanog activity. Mech. Dev. 122, 67–79 (2005) (10.1016/j.mod.2004.08.008) / Mech. Dev. by SY Hatano (2005)
Vallier, L. et al. An efficient system for conditional gene expression in embryonic stem cells and in their in vitro and in vivo differentiated derivatives. Proc. Natl Acad. Sci. USA 98, 2467–2472 (2001) (10.1073/pnas.041617198) / Proc. Natl Acad. Sci. USA by L Vallier (2001)
Robertson, M. et al. Nanog retrotransposed genes with functionally conserved open reading frames. Mamm. Genome 17, 732–743 (2006) (10.1007/s00335-005-0131-y) / Mamm. Genome by M Robertson (2006)
Brons, I. G. et al. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448, 191–195 (2007) (10.1038/nature05950) / Nature by IG Brons (2007)
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Niwa, H. How is pluripotency determined and maintained? Development 134, 635–646 (2007) (10.1242/dev.02787) / Development by H Niwa (2007)
Chambers, I. & Smith, A. Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene 23, 7150–7160 (2004) (10.1038/sj.onc.1207930) / Oncogene by I Chambers (2004)
Lowell, S., Benchoua, A., Heavey, B. & Smith, A. G. Notch promotes neural lineage entry by pluripotent embryonic stem cells. PLoS Biol. 4, e121 (2006) (10.1371/journal.pbio.0040121) / PLoS Biol. by S Lowell (2006)
Ying, Q. L., Stavridis, M., Griffiths, D., Li, M. & Smith, A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nature Biotechnol. 21, 183–186 (2003) (10.1038/nbt780) / Nature Biotechnol. by QL Ying (2003)
Yamaguchi, S., Kimura, H., Tada, M., Nakatsuji, N. & Tada, T. Nanog expression in mouse germ cell development. Gene Expr. Patterns 5, 639–646 (2005) (10.1016/j.modgep.2005.03.001) / Gene Expr. Patterns by S Yamaguchi (2005)
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Toyooka, Y. et al. Expression and intracellular localization of mouse Vasa-homologue protein during germ cell development. Mech. Dev. 93, 139–149 (2000) (10.1016/S0925-4773(00)00283-5) / Mech. Dev. by Y Toyooka (2000)
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Dates

Type	When
Created	17 years, 8 months ago (Dec. 19, 2007, 1:28 p.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 2:12 p.m.)
Indexed	3 days ago (Aug. 31, 2025, 6:16 a.m.)
Issued	17 years, 9 months ago (Dec. 1, 2007)
Published	17 years, 9 months ago (Dec. 1, 2007)
Published Print	17 years, 9 months ago (Dec. 1, 2007)

Funders 0

None

BibTeX

@article{Chambers_2007, title={Nanog safeguards pluripotency and mediates germline development}, volume={450}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature06403}, DOI={10.1038/nature06403}, number={7173}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Chambers, Ian and Silva, Jose and Colby, Douglas and Nichols, Jennifer and Nijmeijer, Bianca and Robertson, Morag and Vrana, Jan and Jones, Ken and Grotewold, Lars and Smith, Austin}, year={2007}, month=dec, pages={1230–1234} }

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