Functional architecture of the retromer cargo-recognition complex
10.1038/nature06216
Crossref journal-article
Springer Science and Business Media LLC
Nature (297)
Bibliography

Hierro, A., Rojas, A. L., Rojas, R., Murthy, N., Effantin, G., Kajava, A. V., Steven, A. C., Bonifacino, J. S., & Hurley, J. H. (2007). Functional architecture of the retromer cargo-recognition complex. Nature, 449(7165), 1063–1067.

Authors 9
  1. Aitor Hierro (first)
  2. Adriana L. Rojas (additional)
  3. Raul Rojas (additional)
  4. Namita Murthy (additional)
  5. Grégory Effantin (additional)
  6. Andrey V. Kajava (additional)
  7. Alasdair C. Steven (additional)
  8. Juan S. Bonifacino (additional)
  9. James H. Hurley (additional)
References 45 Referenced 254
  1. Seaman, M. N. Recycle your receptors with retromer. Trends Cell Biol. 15, 68–75 (2005) (10.1016/j.tcb.2004.12.004) / Trends Cell Biol. by MN Seaman (2005)
  2. Bonifacino, J. S. & Rojas, R. Retrograde transport from endosomes to the trans-Golgi network. Nature Rev. Mol. Cell Biol. 7, 568–579 (2006) (10.1038/nrm1985) / Nature Rev. Mol. Cell Biol. by JS Bonifacino (2006)
  3. Seaman, M. N. J., McCaffery, J. M. & Emr, S. D. A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J. Cell Biol. 142, 665–681 (1998) (10.1083/jcb.142.3.665) / J. Cell Biol. by MNJ Seaman (1998)
  4. Haft, C. R. et al. Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: Assembly into multimeric complexes. Mol. Biol. Cell 11, 4105–4116 (2000) (10.1091/mbc.11.12.4105) / Mol. Biol. Cell by CR Haft (2000)
  5. Arighi, C. N., Hartnell, L. M., Aguilar, R. C., Haft, C. R. & Bonifacino, J. S. Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor. J. Cell Biol. 165, 123–133 (2004) (10.1083/jcb.200312055) / J. Cell Biol. by CN Arighi (2004)
  6. Carlton, J. et al. Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high-curvature membranes and 3-phosphoinositides. Curr. Biol. 14, 1791–1800 (2004) (10.1016/j.cub.2004.09.077) / Curr. Biol. by J Carlton (2004)
  7. Seaman, M. N. Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer. J. Cell Biol. 165, 111–122 (2004) (10.1083/jcb.200312034) / J. Cell Biol. by MN Seaman (2004)
  8. Verges, M. et al. The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor. Nature Cell Biol. 6, 763–769 (2004) (10.1038/ncb1153) / Nature Cell Biol. by M Verges (2004)
  9. Coudreuse, D. Y. M., Roel, G., Betist, M. C., Destree, O. & Korswagen, H. C. Wnt gradient formation requires retromer function in Wnt-producing cells. Science 312, 921–924 (2006) (10.1126/science.1124856) / Science by DYM Coudreuse (2006)
  10. Prasad, B. C. & Clark, S. G. Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans. . Development 133, 1757–1766 (2006) (10.1242/dev.02357) / Development by BC Prasad (2006)
  11. Strochlic, T. I., Setty, T. G., Sitaram, A. & Burd, C. G. Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling. J. Cell Biol. 177, 115–125 (2007) (10.1083/jcb.200609161) / J. Cell Biol. by TI Strochlic (2007)
  12. Small, S. A. et al. Model-guided microarray implicates the retromer complex in Alzheimer’s disease. Ann. Neurol. 58, 909–919 (2005) (10.1002/ana.20667) / Ann. Neurol. by SA Small (2005)
  13. Rojas, R., Kametaka, S., Haft, C. R. & Bonifacino, J. S. Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of the mannose 6-phosphate receptors. Mol. Cell. Biol. 27, 1112–1124 (2007) (10.1128/MCB.00156-06) / Mol. Cell. Biol. by R Rojas (2007)
  14. Wang, D. et al. Crystal structure of human vacuolar protein sorting protein 29 reveals a phosphodiesterase/nuclease-like fold and two protein-protein interaction sites. J. Biol. Chem. 280, 22962–22967 (2005) (10.1074/jbc.M500464200) / J. Biol. Chem. by D Wang (2005)
  15. Collins, B. M., Skinner, C. F., Watson, P. J., Seaman, M. N. & Owen, D. J. Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly. Nature Struct. Mol. Biol. 12, 594–602 (2005) (10.1038/nsmb954) / Nature Struct. Mol. Biol. by BM Collins (2005)
  16. Shi, H., Rojas, R., Bonifacino, J. S. & Hurley, J. H. The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain. Nature Struct. Mol. Biol. 13, 540–548 (2006) (10.1038/nsmb1103) / Nature Struct. Mol. Biol. by H Shi (2006)
  17. Damen, E., Krieger, E., Nielsen, J. E., Eygensteyn, J. & van Leeuwen, J. E. M. The human Vps29 retromer component is a metallo-phosphoesterase for a cation-independent mannose 6-phosphate receptor substrate peptide. Biochem. J. 398, 399–409 (2006) (10.1042/BJ20060033) / Biochem. J. by E Damen (2006)
  18. Collins, B. M., McCoy, A. J., Kent, H. M., Evans, P. R. & Owen, D. J. Molecular architecture and functional model of the endocytic AP2 complex. Cell 109, 523–535 (2002) (10.1016/S0092-8674(02)00735-3) / Cell by BM Collins (2002)
  19. Heldwein, E. E. et al. Crystal structure of the clathrin adaptor protein 1 core. Proc. Natl Acad. Sci. USA 101, 14108–14113 (2004) (10.1073/pnas.0406102101) / Proc. Natl Acad. Sci. USA by EE Heldwein (2004)
  20. Ybe, J. A. et al. Clathrin self-assembly is mediated by a tandemly repeated superhelix. Nature 399, 371–375 (1999) (10.1038/20708) / Nature by JA Ybe (1999)
  21. Fotin, A. et al. Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature 432, 573–579 (2004) (10.1038/nature03079) / Nature by A Fotin (2004)
  22. Fath, S., Mancias, J. D., Bi, X. & Goldberg, J. Structure and organization of coat proteins in the COPII cage. Cell 129, 1251–1252 (2007) (10.1016/j.cell.2007.05.036) / Cell by S Fath (2007)
  23. Misra, S., Puertollano, R., Kato, Y., Bonifacino, J. S. & Hurley, J. H. Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature 415, 933–937 (2002) (10.1038/415933a) / Nature by S Misra (2002)
  24. Shiba, T. et al. Structural basis for recognition of acidic-cluster dileucine sequence by GGA1. Nature 415, 937–941 (2002) (10.1038/415937a) / Nature by T Shiba (2002)
  25. Nothwehr, S. F., Bruinsma, P. & Strawn, L. A. Distinct domains within Vps35p mediate the retrieval of two different cargo proteins from the yeast prevacuolar/endosomal compartment. Mol. Biol. Cell 10, 875–890 (1999) (10.1091/mbc.10.4.875) / Mol. Biol. Cell by SF Nothwehr (1999)
  26. Yang, J. et al. Molecular basis for TPR domain-mediated regulation of protein phosphatase 5. EMBO J. 24, 1–10 (2005) (10.1038/sj.emboj.7600496) / EMBO J. by J Yang (2005)
  27. Groves, M. R. & Barford, D. Topological characteristics of helical repeat proteins. Curr. Opin. Struct. Biol. 9, 383–389 (1999) (10.1016/S0959-440X(99)80052-9) / Curr. Opin. Struct. Biol. by MR Groves (1999)
  28. Conti, E. & Izaurralde, E. Nucleocytoplasmic transport enters the atomic age. Curr. Opin. Cell Biol. 13, 310–319 (2001) (10.1016/S0955-0674(00)00213-1) / Curr. Opin. Cell Biol. by E Conti (2001)
  29. Nothwehr, S. F., Ha, S. A. & Bruinsma, P. Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35p. J. Cell Biol. 151, 297–310 (2000) (10.1083/jcb.151.2.297) / J. Cell Biol. by SF Nothwehr (2000)
  30. Peter, B. J. et al. BAR domains as sensors of membrane curvature: The amphiphysin BAR structure. Science 303, 495–499 (2004) (10.1126/science.1092586) / Science by BJ Peter (2004)
  31. Sheffield, P., Garrard, S. & Derewenda, Z. Overcoming expression and purification problems of RhoGDI using a family of “parallel” expression vectors. Protein Expr. Purif. 15, 34–39 (1999) (10.1006/prep.1998.1003) / Protein Expr. Purif. by P Sheffield (1999)
  32. Hierro, A., Kim, J. & Hurley, J. H. Polycistronic expression and purification of the ESCRT-II endosomal trafficking complex. Methods Enzymol. 403, 322–332 (2005) (10.1016/S0076-6879(05)03027-2) / Methods Enzymol. by A Hierro (2005)
  33. Tan, S. A modular polycistronic expression system for overexpressing protein complexes in Escherichia coli . Protein Expr. Purif. 21, 224–234 (2001) (10.1006/prep.2000.1363) / Protein Expr. Purif. by S Tan (2001)
  34. Terwilliger, T. C. & Berendzen, J. Automated MAD and MIR structure solution. Acta Crystallogr. D 55, 849–861 (1999) (10.1107/S0907444999000839) / Acta Crystallogr. D by TC Terwilliger (1999)
  35. Emsley, P. & Cowtan, K. Coot: model-building tools for molecular graphics. Acta Crystallogr. D 60, 2126–2132 (2004) (10.1107/S0907444904019158) / Acta Crystallogr. D by P Emsley (2004)
  36. Brunger, A. T. et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. D 54, 905–921 (1998) (10.1107/S0907444998003254) / Acta Crystallogr. D by AT Brunger (1998)
  37. Pettit, F. K., Bare, E., Tsai, A. & Bowie, J. U. HotPatch: a statistical approach to finding biologically relevant features on protein surfaces. J. Mol. Biol. 369, 863–879 (2007) (10.1016/j.jmb.2007.03.036) / J. Mol. Biol. by FK Pettit (2007)
  38. Bateman, A. et al. The Pfam protein families database. Nucleic Acids Res. 30, 276–280 (2002) (10.1093/nar/30.1.276) / Nucleic Acids Res. by A Bateman (2002)
  39. Martina, J. A., Moriyama, K. & Bonifacino, J. S. BLOC-3, a protein complex containing the Hermansky-Pudlak syndrome gene products HPS1 and HPS4. J. Biol. Chem. 278, 29376–29384 (2003) (10.1074/jbc.M301294200) / J. Biol. Chem. by JA Martina (2003)
  40. Heymann, J. B. & Belnap, D. M. Bsoft: image processing and molecular modeling for electron microscopy. J. Struct. Biol. 157, 3–18 (2007) (10.1016/j.jsb.2006.06.006) / J. Struct. Biol. by JB Heymann (2007)
  41. Ludtke, S. J., Baldwin, P. R. & Chiu, W. EMAN: semiautomated software for high-resolution single-particle reconstructions. J. Struct. Biol. 128, 82–97 (1999) (10.1006/jsbi.1999.4174) / J. Struct. Biol. by SJ Ludtke (1999)
  42. Frank, J. et al. SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J. Struct. Biol. 116, 190–199 (1996) (10.1006/jsbi.1996.0030) / J. Struct. Biol. by J Frank (1996)
  43. Bucher, P., Karplus, K., Moeri, N. & Hofmann, K. A flexible motif search technique based on generalized profiles. Comput. Chem. 20, 3–23 (1996) (10.1016/S0097-8485(96)80003-9) / Comput. Chem. by P Bucher (1996)
  44. Hofmann, K. & Bucher, P. The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors. Trends Biochem. Sci. 20, 347–349 (1995) (10.1016/S0968-0004(00)89072-6) / Trends Biochem. Sci. by K Hofmann (1995)
  45. Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. Improved methods for building protein models in electron-density maps and the location of errors in these models. Acta Crystallogr. A 47, 110–119 (1991) (10.1107/S0108767390010224) / Acta Crystallogr. A by TA Jones (1991)
Dates
Type When
Created 17 years, 10 months ago (Sept. 23, 2007, 2:04 p.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 2:09 p.m.)
Indexed 1 month, 3 weeks ago (June 30, 2025, 4:02 p.m.)
Issued 17 years, 10 months ago (Sept. 23, 2007)
Published 17 years, 10 months ago (Sept. 23, 2007)
Published Online 17 years, 10 months ago (Sept. 23, 2007)
Published Print 17 years, 10 months ago (Oct. 1, 2007)
Funders 0

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@article{Hierro_2007, title={Functional architecture of the retromer cargo-recognition complex}, volume={449}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature06216}, DOI={10.1038/nature06216}, number={7165}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Hierro, Aitor and Rojas, Adriana L. and Rojas, Raul and Murthy, Namita and Effantin, Grégory and Kajava, Andrey V. and Steven, Alasdair C. and Bonifacino, Juan S. and Hurley, James H.}, year={2007}, month=sep, pages={1063–1067} }