A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes
10.1038/nature04106
Crossref journal-article
Springer Science and Business Media LLC
Nature (297)
Bibliography

Hirano, Y., Hendil, K. B., Yashiroda, H., Iemura, S., Nagane, R., Hioki, Y., Natsume, T., Tanaka, K., & Murata, S. (2005). A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes. Nature, 437(7063), 1381–1385.

Authors 9
  1. Yuko Hirano (first)
  2. Klavs B. Hendil (additional)
  3. Hideki Yashiroda (additional)
  4. Shun-ichiro Iemura (additional)
  5. Ryoichi Nagane (additional)
  6. Yusaku Hioki (additional)
  7. Tohru Natsume (additional)
  8. Keiji Tanaka (additional)
  9. Shigeo Murata (additional)
References 23 Referenced 218
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  2. Glickman, M. H. & Ciechanover, A. The ubiquitin–proteasome proteolytic pathway: destruction for the sake of construction. Physiol. Rev. 82, 373–428 (2002) (10.1152/physrev.00027.2001) / Physiol. Rev. by MH Glickman (2002)
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  5. Unno, M. et al. The structure of the mammalian 20S proteasome at 2.75 Å resolution. Structure (Camb.) 10, 609–618 (2002) (10.1016/S0969-2126(02)00748-7) / Structure (Camb.) by M Unno (2002)
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  7. Gerards, W. L. et al. The human α-type proteasomal subunit HsC8 forms a double ringlike structure, but does not assemble into proteasome-like particles with the β-type subunits HsDelta or HsBPROS26. J. Biol. Chem. 272, 10080–10086 (1997) (10.1074/jbc.272.15.10080) / J. Biol. Chem. by WL Gerards (1997)
  8. Yao, Y. et al. α5 subunit in Trypanosoma brucei proteasome can self-assemble to form a cylinder of four stacked heptamer rings. Biochem. J. 344, 349–358 (1999) (10.1042/bj3440349) / Biochem. J. by Y Yao (1999)
  9. Yang, Y., Fruh, K., Ahn, K. & Peterson, P. A. In vivo assembly of the proteasomal complexes, implications for antigen processing. J. Biol. Chem. 270, 27687–27694 (1995) (10.1074/jbc.270.46.27687) / J. Biol. Chem. by Y Yang (1995)
  10. Chen, P. & Hochstrasser, M. Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assembly. Cell 86, 961–972 (1996) (10.1016/S0092-8674(00)80171-3) / Cell by P Chen (1996)
  11. Schmidtke, G. et al. Analysis of mammalian 20S proteasome biogenesis: the maturation of β-subunits is an ordered two-step mechanism involving autocatalysis. EMBO J. 15, 6887–6898 (1996) (10.1002/j.1460-2075.1996.tb01081.x) / EMBO J. by G Schmidtke (1996)
  12. Nandi, D., Woodward, E., Ginsburg, D. B. & Monaco, J. J. Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor β subunits. EMBO J. 16, 5363–5375 (1997) (10.1093/emboj/16.17.5363) / EMBO J. by D Nandi (1997)
  13. Schmidtke, G., Schmidt, M. & Kloetzel, P. M. Maturation of mammalian 20 S proteasome: purification and characterization of 13 S and 16 S proteasome precursor complexes. J. Mol. Biol. 268, 95–106 (1997) (10.1006/jmbi.1997.0947) / J. Mol. Biol. by G Schmidtke (1997)
  14. Ramos, P. C., Hockendorff, J., Johnson, E. S., Varshavsky, A. & Dohmen, R. J. Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly. Cell 92, 489–499 (1998) (10.1016/S0092-8674(00)80942-3) / Cell by PC Ramos (1998)
  15. Griffin, T. A., Slack, J. P., McCluskey, T. S., Monaco, J. J. & Colbert, R. A. Identification of proteassemblin, a mammalian homologue of the yeast protein, Ump1p, that is required for normal proteasome assembly. Mol. Cell. Biol. Res. Commun. 3, 212–217 (2000) (10.1006/mcbr.2000.0213) / Mol. Cell. Biol. Res. Commun. by TA Griffin (2000)
  16. Witt, E. et al. Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(β5i) incorporation into 20 S proteasomes. J. Mol. Biol. 301, 1–9 (2000) (10.1006/jmbi.2000.3959) / J. Mol. Biol. by E Witt (2000)
  17. Burri, L. et al. Identification and characterization of a mammalian protein interacting with 20S proteasome precursors. Proc. Natl Acad. Sci. USA 97, 10348–10353 (2000) (10.1073/pnas.190268597) / Proc. Natl Acad. Sci. USA by L Burri (2000)
  18. Natsume, T. et al. A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics. Anal. Chem. 74, 4725–4733 (2002) (10.1021/ac020018n) / Anal. Chem. by T Natsume (2002)
  19. Vidal-Taboada, J. M. et al. Down syndrome critical region gene 2: expression during mouse development and in human cell lines indicates a function related to cell proliferation. Biochem. Biophys. Res. Commun. 272, 156–163 (2000) (10.1006/bbrc.2000.2726) / Biochem. Biophys. Res. Commun. by JM Vidal-Taboada (2000)
  20. Bahar, R. et al. Growth retardation, polyploidy, and multinucleation induced by Clast3, a novel cell cycle-regulated protein. J. Biol. Chem. 277, 40012–40019 (2002) (10.1074/jbc.M205345200) / J. Biol. Chem. by R Bahar (2002)
  21. Ahn, K. et al. In vivo characterization of the proteasome regulator PA28. J. Biol. Chem. 271, 18237–18242 (1996) (10.1074/jbc.271.30.18237) / J. Biol. Chem. by K Ahn (1996)
  22. Tanahashi, N. et al. Hybrid proteasomes. Induction by interferon-γ and contribution to ATP-dependent proteolysis. J. Biol. Chem. 275, 14336–14445 (2000) (10.1074/jbc.275.19.14336) / J. Biol. Chem. by N Tanahashi (2000)
  23. Murata, S. et al. Immunoproteasome assembly and antigen presentation in mice lacking both PA28α and PA28β. EMBO J. 20, 5898–5907 (2001) (10.1093/emboj/20.21.5898) / EMBO J. by S Murata (2001)
Dates
Type When
Created 19 years, 9 months ago (Oct. 26, 2005, 1:56 p.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 1:49 p.m.)
Indexed 2 weeks, 1 day ago (Aug. 7, 2025, 4:54 p.m.)
Issued 19 years, 10 months ago (Oct. 1, 2005)
Published 19 years, 10 months ago (Oct. 1, 2005)
Published Print 19 years, 10 months ago (Oct. 1, 2005)
Funders 0

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@article{Hirano_2005, title={A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes}, volume={437}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature04106}, DOI={10.1038/nature04106}, number={7063}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Hirano, Yuko and Hendil, Klavs B. and Yashiroda, Hideki and Iemura, Shun-ichiro and Nagane, Ryoichi and Hioki, Yusaku and Natsume, Tohru and Tanaka, Keiji and Murata, Shigeo}, year={2005}, month=oct, pages={1381–1385} }