DOI: 10.1038/nature03117. Regulation of p53 activity through lysine methylation

Regulation of p53 activity through lysine methylation

10.1038/nature03117

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Chuikov, S., Kurash, J. K., Wilson, J. R., Xiao, B., Justin, N., Ivanov, G. S., McKinney, K., Tempst, P., Prives, C., Gamblin, S. J., Barlev, N. A., & Reinberg, D. (2004). Regulation of p53 activity through lysine methylation. Nature, 432(7015), 353â360.

Authors 12

Sergei Chuikov (first)
Julia K. Kurash (additional)
Jonathan R. Wilson (additional)
Bing Xiao (additional)
Neil Justin (additional)
Gleb S. Ivanov (additional)
Kristine McKinney (additional)
Paul Tempst (additional)
Carol Prives (additional)
Steven J. Gamblin (additional)
Nickolai A. Barlev (additional)
Danny Reinberg (additional)

References 22 Referenced 663

Jenuwein, T. & Allis, C. D. Translating the histone code. Science 293, 1074–1080 (2001) (10.1126/science.1063127) / Science by T Jenuwein (2001)
Wang, H. et al. Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. Mol. Cell 8, 1207–1217 (2001) (10.1016/S1097-2765(01)00405-1) / Mol. Cell by H Wang (2001)
Nishioka, K. et al. Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. Genes Dev. 16, 479–489 (2002) (10.1101/gad.967202) / Genes Dev. by K Nishioka (2002)
Appella, E. & Anderson, C. W. Post-translational modifications and activation of p53 by genotoxic stresses. Eur. J. Biochem. 268, 2764–2772 (2001) (10.1046/j.1432-1327.2001.02225.x) / Eur. J. Biochem. by E Appella (2001)
Shieh, S. Y., Ikeda, M., Taya, Y. & Prives, C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325–334 (1997) (10.1016/S0092-8674(00)80416-X) / Cell by SY Shieh (1997)
Momand, J., Wu, H. H. & Dasgupta, G. MDM2—master regulator of the p53 tumor suppressor protein. Gene 242, 15–29 (2000) (10.1016/S0378-1119(99)00487-4) / Gene by J Momand (2000)
Brooks, C. L. & Gu, W. Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation. Curr. Opin. Cell Biol. 15, 164–171 (2003) (10.1016/S0955-0674(03)00003-6) / Curr. Opin. Cell Biol. by CL Brooks (2003)
Li, M., Luo, J., Brooks, C. L. & Gu, W. Acetylation of p53 inhibits its ubiquitination by Mdm2. J. Biol. Chem. 277, 50607–50611 (2002) (10.1074/jbc.C200578200) / J. Biol. Chem. by M Li (2002)
Luo, J. et al. Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo. Proc. Natl Acad. Sci. USA 101, 2259–2264 (2004) (10.1073/pnas.0308762101) / Proc. Natl Acad. Sci. USA by J Luo (2004)
Gu, W. & Roeder, R. G. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 90, 595–606 (1997) (10.1016/S0092-8674(00)80521-8) / Cell by W Gu (1997)
Barlev, N. A. et al. Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol. Cell 8, 1243–1254 (2001) (10.1016/S1097-2765(01)00414-2) / Mol. Cell by NA Barlev (2001)
Gu, W., Luo, J., Brooks, C. L., Nikolaev, A. Y. & Li, M. Dynamics of the p53 acetylation pathway. Nov. Found. Symp. 259, 197–205 (2004) (10.1002/0470862637.ch14) / Nov. Found. Symp. by W Gu (2004)
Gostissa, M. et al. Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1. Embo J. 18, 6462–6471 (1999) (10.1093/emboj/18.22.6462) / Embo J. by M Gostissa (1999)
Kwek, S. S., Derry, J., Tyner, A. L., Shen, Z. & Gudkov, A. V. Functional analysis and intracellular localization of p53 modified by SUMO-1. Oncogene 20, 2587–2599 (2001) (10.1038/sj.onc.1204362) / Oncogene by SS Kwek (2001)
Rodriguez, M. S. et al. SUMO-1 modification activates the transcriptional response of p53. Embo J. 18, 6455–6461 (1999) (10.1093/emboj/18.22.6455) / Embo J. by MS Rodriguez (1999)
Kouskouti, A., Scheer, E., Staub, A., Tora, L. & Talianidis, I. Gene-specific modulation of TAF10 function by SET9-mediated methylation. Mol. Cell 14, 175–182 (2004) (10.1016/S1097-2765(04)00182-0) / Mol. Cell by A Kouskouti (2004)
Xiao, B. et al. Structure and catalytic mechanism of the human histone methyltransferase SET7/9. Nature 421, 652–656 (2003) (10.1038/nature01378) / Nature by B Xiao (2003)
Grand, R. J. et al. The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression. Virology 210, 323–334 (1995) (10.1006/viro.1995.1349) / Virology by RJ Grand (1995)
Tachibana, M., Sugimoto, K., Fukushima, T. & Shinkai, Y. SET domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. J. Biol. Chem. 276, 25309–25317 (2001) (10.1074/jbc.M101914200) / J. Biol. Chem. by M Tachibana (2001)
Otwinowski, Z. & Minor, W. in Data Collection and Processing (eds Sawyer, L., Isaacs, N. & Bailey, S.) 552–562 (SERC Daresbury Laboratory, Warrington, 1993) / Data Collection and Processing by Z Otwinowski (1993)
CCP4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760–763 (1994) (10.1107/S0907444994003112) / Acta Crystallogr. D by CCP4 (1994)
Jones, T. A., Zhou, J. Y., Cowan, S. W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A 47, 110–119 (1991)

Dates

Type	When
Created	20 years, 10 months ago (Nov. 3, 2004, 1:16 p.m.)
Deposited	1 year, 7 months ago (Jan. 14, 2024, 6:25 p.m.)
Indexed	2 hours, 14 minutes ago (Sept. 7, 2025, 4:42 a.m.)
Issued	20 years, 10 months ago (Nov. 1, 2004)
Published	20 years, 10 months ago (Nov. 1, 2004)
Published Online	20 years, 10 months ago (Nov. 3, 2004)
Published Print	20 years, 10 months ago (Nov. 1, 2004)

Funders 0

None

BibTeX

@article{Chuikov_2004, title={Regulation of p53 activity through lysine methylation}, volume={432}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature03117}, DOI={10.1038/nature03117}, number={7015}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Chuikov, Sergei and Kurash, Julia K. and Wilson, Jonathan R. and Xiao, Bing and Justin, Neil and Ivanov, Gleb S. and McKinney, Kristine and Tempst, Paul and Prives, Carol and Gamblin, Steven J. and Barlev, Nickolai A. and Reinberg, Danny}, year={2004}, month=nov, pages={353–360} }

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