DOI: 10.1038/nature02679. Recognition of RNA polymerase II carboxy-terminal domain by 3′-RNA-processing factors

Recognition of RNA polymerase II carboxy-terminal domain by 3′-RNA-processing factors

10.1038/nature02679

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Meinhart, A., & Cramer, P. (2004). Recognition of RNA polymerase II carboxy-terminal domain by 3â²-RNA-processing factors. Nature, 430(6996), 223â226.

Authors 2

Anton Meinhart (first)
Patrick Cramer (additional)

References 30 Referenced 256

Hirose, Y. & Manley, J. L. RNA polymerase II and the integration of nuclear events. Genes Dev. 14, 1415–1429 (2000) (10.1101/gad.14.12.1415) / Genes Dev. by Y Hirose (2000)
Proudfoot, N. J., Furger, A. & Dye, M. J. Integrating mRNA processing with transcription. Cell 108, 501–512 (2002) (10.1016/S0092-8674(02)00617-7) / Cell by NJ Proudfoot (2002)
Cramer, P., Bushnell, D. A. & Kornberg, R. D. Structural basis of transcription: RNA polymerase II at 2.8Ångstrom resolution. Science 292, 1863–1876 (2001) (10.1126/science.1059493) / Science by P Cramer (2001)
Komarnitsky, P., Cho, E. J. & Buratowski, S. Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev. 14, 2452–2460 (2000) (10.1101/gad.824700) / Genes Dev. by P Komarnitsky (2000)
Ahn, S. H., Kim, M. & Buratowski, S. Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3′ end processing. Mol. Cell 13, 67–76 (2004) (10.1016/S1097-2765(03)00492-1) / Mol. Cell by SH Ahn (2004)
Ni, Z., Schwartz, B. E., Werner, J., Suarez, J. R. & Lis, J. T. Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genes. Mol. Cell 13, 55–65 (2004) (10.1016/S1097-2765(03)00526-4) / Mol. Cell by Z Ni (2004)
Buratowski, S. The CTD code. Nature Struct. Biol. 10, 679–680 (2003) (10.1038/nsb0903-679) / Nature Struct. Biol. by S Buratowski (2003)
Yuryev, A. et al. The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins. Proc. Natl Acad. Sci. USA 93, 6975–6980 (1996) (10.1073/pnas.93.14.6975) / Proc. Natl Acad. Sci. USA by A Yuryev (1996)
Patturajan, M., Wei, X., Berezney, R. & Corden, J. L. A nuclear matrix protein interacts with the phosphorylated C-terminal domain of RNA polymerase II. Mol. Cell. Biol. 18, 2406–2415 (1998) (10.1128/MCB.18.4.2406) / Mol. Cell. Biol. by M Patturajan (1998)
Steinmetz, E. J., Conrad, N. K., Brow, D. A. & Corden, J. L. RNA-binding protein Nrd1 directs poly(A)-independent 3′-end formation of RNA polymerase II transcripts. Nature 413, 327–331 (2001) (10.1038/35095090) / Nature by EJ Steinmetz (2001)
Barilla, D., Lee, B. A. & Proudfoot, N. J. Cleavage/polyadenylation factor IA associates with the carboxyl-terminal domain of RNA polymerase II in Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA 98, 445–450 (2001) / Proc. Natl Acad. Sci. USA by D Barilla (2001)
Misra, S., Puertollano, R., Kato, Y., Bonifacino, J. S. & Hurley, J. H. Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature 415, 933–937 (2002) (10.1038/415933a) / Nature by S Misra (2002)
Conti, E., Uy, M., Leighton, L., Blobel, G. & Kuriyan, J. Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin α. Cell 94, 193–204 (1998) (10.1016/S0092-8674(00)81419-1) / Cell by E Conti (1998)
Sadowski, M., Dichtl, B., Hubner, W. & Keller, W. Independent functions of yeast Pcf11p in pre-mRNA 3′ end processing and in transcription termination. EMBO J. 22, 2167–2177 (2003) (10.1093/emboj/cdg200) / EMBO J. by M Sadowski (2003)
West, M. L. & Corden, J. L. Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations. Genetics 140, 1223–1233 (1995) (10.1093/genetics/140.4.1223) / Genetics by ML West (1995)
Suzuki, M. SPXX, a frequent sequence motif in gene regulatory proteins. J. Mol. Biol. 207, 61–84 (1989) (10.1016/0022-2836(89)90441-5) / J. Mol. Biol. by M Suzuki (1989)
Licatalosi, D. D. et al. Functional interaction of yeast pre-mRNA 3′ end processing factors with RNA polymerase II. Mol. Cell 9, 1101–1111 (2002) (10.1016/S1097-2765(02)00518-X) / Mol. Cell by DD Licatalosi (2002)
Verdecia, M. A., Bowman, M. E., Lu, K. P., Hunter, T. & Noel, J. P. Structural basis for phosphoserine–proline recognition by group IV WW domains. Nature Struct. Biol. 7, 639–643 (2000) (10.1038/77929) / Nature Struct. Biol. by MA Verdecia (2000)
Fabrega, C., Shen, V., Shuman, S. & Lima, C. D. Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II. Mol. Cell 11, 1549–1561 (2003) (10.1016/S1097-2765(03)00187-4) / Mol. Cell by C Fabrega (2003)
Kumaki, Y., Matsushima, N., Yoshida, H., Nitta, K. & Hikichi, K. Structure of the YSPTSPS repeat containing two SPXX motifs in the CTD of RNA polymerase II: NMR studies of cyclic model peptides reveal that the SPTS turn is more stable than SPSY in water. Biochim. Biophys. Acta. 1548, 81–93 (2001) (10.1016/S0167-4838(01)00216-3) / Biochim. Biophys. Acta. by Y Kumaki (2001)
Cagas, P. M. & Corden, J. L. Structural studies of a synthetic peptide derived from the carboxyl-terminal domain of RNA polymerase II. Proteins 21, 149–160 (1995) (10.1002/prot.340210209) / Proteins by PM Cagas (1995)
Meredith, G. D. et al. The C-terminal domain revealed in the structure of RNA polymerase II. J. Mol. Biol. 258, 413–419 (1996) (10.1006/jmbi.1996.0258) / J. Mol. Biol. by GD Meredith (1996)
Zhang, J. & Corden, J. L. Phosphorylation causes a conformational change in the carboxyl-terminal domain of the mouse RNA polymerase II largest subunit. J. Biol. Chem. 266, 2297–2302 (1991) (10.1016/S0021-9258(18)52243-2) / J. Biol. Chem. by J Zhang (1991)
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307–326 (1997) (10.1016/S0076-6879(97)76066-X) / Methods Enzymol. by Z Otwinowski (1997)
Kabsch, W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J. Appl. Crystallogr. 26, 795–800 (1993) (10.1107/S0021889893005588) / J. Appl. Crystallogr. by W Kabsch (1993)
Smith, G. D., Nagar, B., Rini, J. M., Hauptman, H. A. & Blessing, R. H. The use of SnB to determine an anomalous scattering substructure. Acta. Crystallogr. D 54, 799–804 (1998) (10.1107/S0907444997018805) / Acta. Crystallogr. D by GD Smith (1998)
Terwilliger, T. C. Automated structure solution, density modification and model building. Acta. Crystallogr. 58, 1937–1940 (2002) (10.1107/S0108767302087378) / Acta. Crystallogr. by TC Terwilliger (2002)
Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta. Crystallogr. A 47, 110–119 (1991) (10.1107/S0108767390010224) / Acta. Crystallogr. A by TA Jones (1991)
Brünger, A. T. et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta. Crystallogr. D 54, 905–921 (1998) (10.1107/S0907444998003254) / Acta. Crystallogr. D by AT Brünger (1998)
Armache, K. J., Kettenberger, H. & Cramer, P. Architecture of initiation-competent 12-subunit RNA polymerase II. Proc. Natl Acad. Sci. USA 100, 6964–6968 (2003) (10.1073/pnas.1030608100) / Proc. Natl Acad. Sci. USA by KJ Armache (2003)

Dates

Type	When
Created	21 years, 1 month ago (July 7, 2004, 2:08 p.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 2:24 p.m.)
Indexed	1 month, 2 weeks ago (July 2, 2025, 11:58 a.m.)
Issued	21 years, 1 month ago (July 1, 2004)
Published	21 years, 1 month ago (July 1, 2004)
Published Print	21 years, 1 month ago (July 1, 2004)

Funders 0

None

BibTeX

@article{Meinhart_2004, title={Recognition of RNA polymerase II carboxy-terminal domain by 3′-RNA-processing factors}, volume={430}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature02679}, DOI={10.1038/nature02679}, number={6996}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Meinhart, Anton and Cramer, Patrick}, year={2004}, month=jul, pages={223–226} }

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