DOI: 10.1038/nature02404. From molecular noise to behavioural variability in a single bacterium

From molecular noise to behavioural variability in a single bacterium

10.1038/nature02404

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Korobkova, E., Emonet, T., Vilar, J. M. G., Shimizu, T. S., & Cluzel, P. (2004). From molecular noise to behavioural variability in a single bacterium. Nature, 428(6982), 574â578.

Authors 5

Ekaterina Korobkova (first)
Thierry Emonet (additional)
Jose M. G. Vilar (additional)
Thomas S. Shimizu (additional)
Philippe Cluzel (additional)

References 24 Referenced 384

Bourret, R. B. & Stock, A. M. Molecular information processing: lessons from bacterial chemotaxis. J. Biol. Chem. 277, 9625–9628 (2002) (10.1074/jbc.R100066200) / J. Biol. Chem. by RB Bourret (2002)
Spiro, P. A., Parkinson, J. S. & Othmer, H. G. A model of excitation and adaptation in bacterial chemotaxis. Proc. Natl Acad. Sci. USA 94, 7263–7268 (1997) (10.1073/pnas.94.14.7263) / Proc. Natl Acad. Sci. USA by PA Spiro (1997)
Barkai, N. & Leibler, S. Robustness in simple biochemical networks. Nature 387, 913–917 (1997) (10.1038/43199) / Nature by N Barkai (1997)
Alon, U. et al. Response regulator output in bacterial chemotaxis. EMBO J. 17, 4238–4248 (1998) (10.1093/emboj/17.15.4238) / EMBO J. by U Alon (1998)
Alon, U., Surette, M. G., Barkai, N. & Leibler, S. Robustness in bacterial chemotaxis. Nature 397, 168–171 (1999) (10.1038/16483) / Nature by U Alon (1999)
Morton-Firth, C. J., Shimizu, T. S. & Bray, D. A free-energy-based stochastic simulation of the Tar receptor complex. J. Mol. Biol. 286, 1059–1074 (1999) (10.1006/jmbi.1999.2535) / J. Mol. Biol. by CJ Morton-Firth (1999)
Morton-Firth, C. J. & Bray, D. Predicting temporal fluctuations in an intracellular signalling pathway. J. Theor. Biol. 192, 117–128 (1998) (10.1006/jtbi.1997.0651) / J. Theor. Biol. by CJ Morton-Firth (1998)
Katz, B. & Miledi, R. Statistical nature of acetycholine potential and its molecular components. J. Physiol. (Lond.) 224, 665–699 (1972) (10.1113/jphysiol.1972.sp009918) / J. Physiol. (Lond.) by B Katz (1972)
Samuel, A. D. & Berg, H. C. Fluctuation analysis of rotational speeds of the bacterial flagellar motor. Proc. Natl Acad. Sci. USA 92, 3502–3506 (1995) (10.1073/pnas.92.8.3502) / Proc. Natl Acad. Sci. USA by AD Samuel (1995)
Rao, C. V., Wolf, D. M. & Arkin, A. P. Control, exploitation and tolerance of intracellular noise. Nature 420, 231–237 (2002) (10.1038/nature01258) / Nature by CV Rao (2002)
Larsen, S. H., Reader, R. W., Kort, E. N., Tso, W. W. & Adler, J. Change in direction of flagellar rotation is the basis of the chemotactic response in Escherichia coli. Nature 249, 74–77 (1974) (10.1038/249074a0) / Nature by SH Larsen (1974)
Cluzel, P., Surette, M. & Leibler, S. An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells. Science 287, 1652–1655 (2000) (10.1126/science.287.5458.1652) / Science by P Cluzel (2000)
Block, S. M., Segall, J. E. & Berg, H. C. Adaptation kinetics in bacterial chemotaxis. J. Bacteriol. 154, 312–323 (1983) (10.1128/jb.154.1.312-323.1983) / J. Bacteriol. by SM Block (1983)
Ishihara, A., Segall, J. E., Block, S. M. & Berg, H. C. Coordination of flagella on filamentous cells of Escherichia coli. J. Bacteriol. 155, 228–237 (1983) (10.1128/jb.155.1.228-237.1983) / J. Bacteriol. by A Ishihara (1983)
Khan, S. & Macnab, R. M. The steady-state counterclockwise/clockwise ratio of bacterial flagellar motors is regulated by protonmotive force. J. Mol. Biol. 138, 563–597 (1980) (10.1016/S0022-2836(80)80018-0) / J. Mol. Biol. by S Khan (1980)
Fahrner, K. A. Studies of Bacterial Flagellar Motors and Filaments. PhD thesis, Harvard Univ. (1995) / Studies of Bacterial Flagellar Motors and Filaments by KA Fahrner (1995)
Yi, T. M., Huang, Y., Simon, M. I. & Doyle, J. Robust perfect adaptation in bacterial chemotaxis through integral feedback control. Proc. Natl Acad. Sci. USA 97, 4649–4653 (2000) (10.1073/pnas.97.9.4649) / Proc. Natl Acad. Sci. USA by TM Yi (2000)
Asakura, S. & Honda, H. Two-state model for bacterial chemoreceptor proteins. The role of multiple methylation. J. Mol. Biol. 176, 349–367 (1984) (10.1016/0022-2836(84)90494-7) / J. Mol. Biol. by S Asakura (1984)
Goldbeter, A. & Koshland, D. E. Jr An amplified sensitivity arising from covalent modification in biological systems. Proc. Natl Acad. Sci. USA 78, 6840–6844 (1981) (10.1073/pnas.78.11.6840) / Proc. Natl Acad. Sci. USA by A Goldbeter (1981)
Levit, M. N. & Stock, J. B. Receptor methylation controls the magnitude of stimulus-response coupling in bacterial chemotaxis. J. Biol. Chem. 277, 36760–36765 (2002) (10.1074/jbc.M204325200) / J. Biol. Chem. by MN Levit (2002)
Detwiler, P. B., Ramanathan, S., Sengupta, A. & Shraiman, B. I. Engineering aspects of enzymatic signal transduction: photoreceptors in the retina. Biophys. J. 79, 2801–2817 (2000) (10.1016/S0006-3495(00)76519-2) / Biophys. J. by PB Detwiler (2000)
Elf, J., Paulsson, J., Berg, O. G. & Ehrenberg, M. Near-critical phenomena in intracellular metabolite pools. Biophys. J. 84, 154–170 (2003) (10.1016/S0006-3495(03)74839-5) / Biophys. J. by J Elf (2003)
Viswanathan, G. M. et al. Optimizing the success of random searches. Nature 401, 911–914 (1999) (10.1038/44831) / Nature by GM Viswanathan (1999)
Spudich, J. L. & Koshland, D. E. Jr Non-genetic individuality: chance in the single cell. Nature 262, 467–471 (1976) (10.1038/262467a0) / Nature by JL Spudich (1976)

Dates

Type	When
Created	21 years, 5 months ago (April 1, 2004, 9:06 a.m.)
Deposited	1 year, 7 months ago (Jan. 10, 2024, 9:03 p.m.)
Indexed	3 weeks, 5 days ago (Aug. 6, 2025, 9:45 a.m.)
Issued	21 years, 5 months ago (April 1, 2004)
Published	21 years, 5 months ago (April 1, 2004)
Published Online	21 years, 5 months ago (April 1, 2004)
Published Print	21 years, 5 months ago (April 1, 2004)

Funders 0

None

BibTeX

@article{Korobkova_2004, title={From molecular noise to behavioural variability in a single bacterium}, volume={428}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature02404}, DOI={10.1038/nature02404}, number={6982}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Korobkova, Ekaterina and Emonet, Thierry and Vilar, Jose M. G. and Shimizu, Thomas S. and Cluzel, Philippe}, year={2004}, month=apr, pages={574–578} }

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        "name": "ArticleHistory",
        "label": "Article History"
      }
    },
    {
      "value": "5 February 2004",
      "order": 2,
      "name": "accepted",
      "label": "Accepted",
      "group": {
        "name": "ArticleHistory",
        "label": "Article History"
      }
    },
    {
      "value": "1 April 2004",
      "order": 3,
      "name": "first_online",
      "label": "First Online",
      "group": {
        "name": "ArticleHistory",
        "label": "Article History"
      }
    },
    {
      "value": "The authors declare that they have no competing financial interests.",
      "order": 1,
      "name": "Ethics",
      "group": {
        "name": "EthicsHeading",
        "label": "Competing interests"
      }
    }
  ]
}