DOI: 10.1038/nature01385. Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

10.1038/nature01385

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Wong, K.-K., Maser, R. S., Bachoo, R. M., Menon, J., Carrasco, D. R., Gu, Y., Alt, F. W., & DePinho, R. A. (2003). Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature, 421(6923), 643â648.

Authors 8

Kwok-Kin Wong (first)
Richard S. Maser (additional)
Robert M. Bachoo (additional)
Jayant Menon (additional)
Daniel R. Carrasco (additional)
Yansong Gu (additional)
Frederick W. Alt (additional)
Ronald A. DePinho (additional)

References 30 Referenced 310

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Lee, H. W. et al. Essential role of mouse telomerase in highly proliferative organs. Nature 392, 569–574 (1998) (10.1038/33345) / Nature by HW Lee (1998)
Blasco, M. A. et al. Telomere shortening and tumour formation by mouse cells lacking telomerase RNA. Cell 91, 25–34 (1997) (10.1016/S0092-8674(01)80006-4) / Cell by MA Blasco (1997)
Borghesani, P. R. et al. Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice. Proc. Natl Acad. Sci. USA 97, 3336–3341 (2000) (10.1073/pnas.97.7.3336) / Proc. Natl Acad. Sci. USA by PR Borghesani (2000)
Kastan, M. B. & Lim, D. S. The many substrates and functions of ATM. Nature Rev. Mol. Cell Biol. 1, 179–186 (2000) (10.1038/35043058) / Nature Rev. Mol. Cell Biol. by MB Kastan (2000)
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Barlow, C. et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 86, 159–171 (1996) (10.1016/S0092-8674(00)80086-0) / Cell by C Barlow (1996)
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Vaziri, H. et al. ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase. EMBO J. 16, 6018–6033 (1997) (10.1093/emboj/16.19.6018) / EMBO J. by H Vaziri (1997)
Hande, M. P., Balajee, A. S., Tchirkov, A., Wynshaw-Boris, A. & Lansdorp, P. M. Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. Hum. Mol. Genet. 10, 519–528 (2001) (10.1093/hmg/10.5.519) / Hum. Mol. Genet. by MP Hande (2001)
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Dates

Type	When
Created	22 years, 6 months ago (Feb. 5, 2003, 1:21 p.m.)
Deposited	7 months ago (Jan. 28, 2025, 9:25 p.m.)
Indexed	1 week, 3 days ago (Aug. 24, 2025, 6:59 p.m.)
Issued	22 years, 7 months ago (Jan. 22, 2003)
Published	22 years, 7 months ago (Jan. 22, 2003)
Published Online	22 years, 7 months ago (Jan. 22, 2003)
Published Print	22 years, 6 months ago (Feb. 6, 2003)

Funders 0

None

BibTeX

@article{Wong_2003, title={Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing}, volume={421}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/nature01385}, DOI={10.1038/nature01385}, number={6923}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Wong, Kwok-Kin and Maser, Richard S. and Bachoo, Robert M. and Menon, Jayant and Carrasco, Daniel R. and Gu, Yansong and Alt, Frederick W. and DePinho, Ronald A.}, year={2003}, month=jan, pages={643–648} }

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