DOI: 10.1038/jid.2008.131. Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis

Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis

10.1038/jid.2008.131

Crossref journal-article

Elsevier BV

Journal of Investigative Dermatology (78)

Bibliography

Ellison, T. I., Smith, M. K., Gilliam, A. C., & MacDonald, P. N. (2008). Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis. Journal of Investigative Dermatology, 128(10), 2508â2517.

Authors 4

Tara I. Ellison (first)
Molly K. Smith (additional)
Anita C. Gilliam (additional)
Paul N. MacDonald (additional)

References 36 Referenced 129

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10.1093/jn/134.12.3472S / J Nutr / Vitamin D and skin cancer by Bikle (2004)
10.1111/j.0022-202X.2004.22424.x / J Invest Dermatol / 25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis by Bikle (2004)
10.1021/bi00355a013 / Biochemistry / Neonatal human foreskin keratinocytes produce 1,25-dihydroxyvitamin D3 by Bikle (1986)
10.1128/MCB.14.5.3329 / Mol Cell Biol / Ligand modulates the conversion of DNA-bound vitamin D3 receptor (VDR) homodimers into VDR-retinoid X receptor heterodimers by Cheskis (1994)
{'key': '10.1038/jid.2008.131_bb0040', 'first-page': '5426', 'article-title': 'Inhibition of tumor promotion in mouse skin by 1 alpha,25-dihydroxyvitamin D3', 'volume': '45', 'author': 'Chida', 'year': '1985', 'journal-title': 'Cancer Res'} / Cancer Res / Inhibition of tumor promotion in mouse skin by 1 alpha,25-dihydroxyvitamin D3 by Chida (1985)
10.1210/endo.142.7.8281 / Endocrinology / Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets by Dardenne (2001)
10.1016/S8756-3282(03)00023-1 / Bone / Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1) by Dardenne (2003)
10.1046/j.0022-202x.2001.01478.x / J Invest Dermatol / Solar-simulated skin adaptation and its effect on subsequent UV-induced epidermal DNA damage by de Winter (2001)
10.1016/j.jsbmb.2006.11.016 / J Steroid Biochem Mol Biol / In vivo relevance for photoprotection by the vitamin D rapid response pathway by Dixon (2007)
10.1074/jbc.M609717200 / J Biol Chem / Evidence for 1,25-dihydroxyvitamin D3-independent transactivation by the vitamin D receptor: uncoupling the receptor and ligand in keratinocytes by Ellison (2007)
10.1210/mend.16.7.0866 / Mol Endocrinol / Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D by Erben (2002)
{'key': '10.1038/jid.2008.131_bb0075', 'first-page': '1961', 'article-title': 'Cloning of human 25-hydroxyvitamin D-1 alpha-hydroxylase and mutations causing vitamin D-dependent rickets type 1', 'volume': '11', 'author': 'Fu', 'year': '1997', 'journal-title': 'Mol Endocrinol'} / Mol Endocrinol / Cloning of human 25-hydroxyvitamin D-1 alpha-hydroxylase and mutations causing vitamin D-dependent rickets type 1 by Fu (1997)
10.1016/S0021-9258(19)44557-2 / J Biol Chem / 25-Hydroxycholecalciferol-1-hydroxylase. Subcellular location and properties by Gray (1972)
10.1056/NEJMra070553 / N Engl J Med / Vitamin D deficiency by Holick (2007)
10.1126/science.2849209 / Science / Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets by Hughes (1988)
10.1016/S0022-2836(64)80223-0 / J Mol Biol / The ultraviolet photochemistry of thymidylyl-(3′–5′)-thymidine by Johns (1964)
10.1073/pnas.86.12.4455 / Proc Natl Acad Sci USA / Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3 by Kerner (1989)
10.1038/355446a0 / Nature / Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling by Kliewer (1992)
10.1073/pnas.94.2.526 / Proc Natl Acad Sci USA / A p53-independent damage-sensing mechanism that functions as a checkpoint at the G1/S transition in Chinese hamster ovary cells by Lee (1997)
10.1210/endo.139.10.6262 / Endocrinology / Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice by Li (1998)
10.1073/pnas.94.18.9831 / Proc Natl Acad Sci USA / Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia by Li (1997)
10.1128/MCB.4.9.1689 / Mol Cell Biol / UV irradiation stimulates levels of p53 cellular tumor antigen in nontransformed mouse cells by Maltzman (1984)
{'key': '10.1038/jid.2008.131_bb0130', 'first-page': '1', 'article-title': 'Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine', 'volume': '2002', 'author': 'Matsumura', 'year': '2002', 'journal-title': 'Expert Rev Mol Med'} / Expert Rev Mol Med / Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine by Matsumura (2002)
10.1038/nrc861 / Nat Rev Cancer / p73: friend or foe in tumorigenesis by Melino (2002)
10.1073/pnas.131029498 / Proc Natl Acad Sci USA / Targeted ablation of the 25-hydroxyvitamin D 1alpha-hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction by Panda (2001)
{'key': '10.1038/jid.2008.131_bb0145', 'first-page': '1387', 'article-title': 'UVB radiation induces p21Cip1/WAF1 and mediates G1 and S phase checkpoints', 'volume': '12', 'author': 'Petrocelli', 'year': '1996', 'journal-title': 'Oncogene'} / Oncogene / UVB radiation induces p21Cip1/WAF1 and mediates G1 and S phase checkpoints by Petrocelli (1996)
10.1210/endo.141.6.7515 / Endocrinology / Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice by Sakai (2000)
10.1073/pnas.48.7.1250 / Proc Natl Acad Sci USA / Evidence that ultraviolet-induced thymine dimers in DNA cause biological damage by Setlow (1962)
10.1101/gad.11.24.3471 / Genes Dev / DNA damage induces phosphorylation of the amino terminus of p53 by Siliciano (1997)
10.1210/me.2004-0415 / Mol Endocrinol / Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis by Skorija (2005)
10.1359/jbmr.1997.12.10.1552 / J Bone Miner Res / The 25-hydroxyvitamin D 1-alpha-hydroxylase gene maps to the pseudovitamin D-deficiency rickets (PDDR) disease locus by St-Arnaud (1997)
10.1073/pnas.231474698 / Proc Natl Acad Sci USA / Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects by Van Cromphaut (2001)
10.1038/ng0897-391 / Nat Genet / Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning by Yoshizawa (1997)
10.1093/carcin/23.12.2103 / Carcinogenesis / Vitamin D3 receptor ablation sensitizes skin to chemically induced tumorigenesis by Zinser (2002)

Dates

Type	When
Created	17 years, 3 months ago (May 29, 2008, 6:42 a.m.)
Deposited	3 years, 11 months ago (Sept. 11, 2021, 3:43 a.m.)
Indexed	2 months ago (July 2, 2025, 11:16 a.m.)
Issued	16 years, 11 months ago (Oct. 1, 2008)
Published	16 years, 11 months ago (Oct. 1, 2008)
Published Print	16 years, 11 months ago (Oct. 1, 2008)

Funders 0

None

BibTeX

@article{Ellison_2008, title={Inactivation of the Vitamin D Receptor Enhances Susceptibility of Murine Skin to UV-Induced Tumorigenesis}, volume={128}, ISSN={0022-202X}, url={http://dx.doi.org/10.1038/jid.2008.131}, DOI={10.1038/jid.2008.131}, number={10}, journal={Journal of Investigative Dermatology}, publisher={Elsevier BV}, author={Ellison, Tara I. and Smith, Molly K. and Gilliam, Anita C. and MacDonald, Paul N.}, year={2008}, month=oct, pages={2508–2517} }

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