DOI: 10.1038/icb.1962.54. ACTIVATION OF HAGEMAN FACTOR BY SATURATED FATTY ACIDS

ACTIVATION OF HAGEMAN FACTOR BY SATURATED FATTY ACIDS

10.1038/icb.1962.54

Crossref journal-article

Wiley

Australian Journal of Experimental Biology and Medical Science (311)

Abstract

SUMMARYThe effect of suspensions of saturated fatty acids or oleic acid on the coagulation of plasma and on the release of plasma kinin was determined by quantitative methods. The activity of the saturated series (C8‐C22) increases enormously with the length of the carbon chain. Oleic acid is practically inactive. Evidence is presented that the reaction is mediated by adsorption and activation of Hageman factor by the fatty acid micelles. The differences between the activity of the fatty acids are related to the physical conditions at the surface of the particles.

Bibliography

Margolis, J. (1962). ACTIVATION OF HAGEMAN FACTOR BY SATURATED FATTY ACIDS. Australian Journal of Experimental Biology and Medical Science, 40(6), 505â513. Portico.

Authors 1

J Margolis (first)

References 0 Referenced 44

None

Dates

Type	When
Created	17 years, 8 months ago (Dec. 15, 2007, 5:24 a.m.)
Deposited	1 year, 11 months ago (Sept. 29, 2023, 5:41 p.m.)
Indexed	2 months ago (June 25, 2025, 8:34 p.m.)
Issued	62 years, 8 months ago (Dec. 1, 1962)
Published	62 years, 8 months ago (Dec. 1, 1962)
Published Online	62 years, 8 months ago (Dec. 1, 1962)
Published Print	62 years, 8 months ago (Dec. 1, 1962)

Funders 0

None

BibTeX

@article{Margolis_1962, title={ACTIVATION OF HAGEMAN FACTOR BY SATURATED FATTY ACIDS}, volume={40}, ISSN={0818-9641}, url={http://dx.doi.org/10.1038/icb.1962.54}, DOI={10.1038/icb.1962.54}, number={6}, journal={Australian Journal of Experimental Biology and Medical Science}, publisher={Wiley}, author={Margolis, J}, year={1962}, month=dec, pages={505–513} }

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