DOI: 10.1038/990025. Synexpression groups in eukaryotes

Synexpression groups in eukaryotes

10.1038/990025

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Niehrs, C., & Pollet, N. (1999). Synexpression groups in eukaryotes. Nature, 402(6761), 483â487.

Authors 2

Christof Niehrs (first)
Nicolas Pollet (additional)

References 42 Referenced 316

Brown,P. O. & Botstein,D. Exploring the new world of the genome with DNA microarrays. Nat. Genet. 21, 33 –37 (1999). (10.1038/4462) / Nat. Genet. by PO Brown (1999)
Gerhold,D., Rushmore,T. & Caskey,C. T. DNA chips: promising toys have become powerful tools. Trends Biochem. Sci. 24, 168– 173 (1999). (10.1016/S0968-0004(99)01382-1) / Trends Biochem. Sci. by D Gerhold (1999)
Lipshutz,R. J., Fodor,S. P., Gingeras,T. R. & Lockhart,D. J. High density synthetic oligonucleotide arrays. Nat. Genet. 21, 20–24 (1999). (10.1038/4447) / Nat. Genet. by RJ Lipshutz (1999)
Bowtell,D. D. Options available—from start to finish—for obtaining expression data by microarray. Nat. Genet. 21, 25– 32 (1999). (10.1038/4455) / Nat. Genet. by DD Bowtell (1999)
Cheung,V. G. et al. Making and reading microarrays. Nat. Genet. 21, 15–19 (1999). (10.1038/4439) / Nat. Genet. by VG Cheung (1999)
Duggan,D. J., Bittner,M., Chen,Y., Meltzer,P. & Trent,J. M. Expression profiling using cDNA microarrays. Nat. Genet. 21, 10–14 ( 1999). (10.1038/4434) / Nat. Genet. by DJ Duggan (1999)
Bassett,D. E., Eisen,M. B. & Boguski,M. S. Gene expression informatics—it's all in your mine. Nat. Genet. 21, 51– 55 (1999). (10.1038/4478) / Nat. Genet. by DE Bassett (1999)
DeRisi,J. L., Vishwanath,R. I. & Brown,P. O. Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 278, 680–686 (1997). (10.1126/science.278.5338.680) / Science by JL DeRisi (1997)
Chu,S et al. The transcriptional program of sporulation in budding yeast. Science 282, 699–705 ( 1998). (10.1126/science.282.5389.699) / Science by S Chu (1998)
Cho,R. J. et al. A genome-wide transcriptional analysis of the mitotic cell cycle. Mol. Cell 2, 65–73 (1998). (10.1016/S1097-2765(00)80114-8) / Mol. Cell by RJ Cho (1998)
Spellman,P. T. et al. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol. Biol. Cell 9, 3273– 97 (1998). (10.1091/mbc.9.12.3273) / Mol. Biol. Cell by PT Spellman (1998)
Vishwanath,R. I. et al. The transcriptional program in the response of human fibroblasts to serum. Science 283, 83– 87 (1999). (10.1126/science.283.5398.83) / Science by RI Vishwanath (1999)
Wen,X. et al. Large-scale temporal gene expression mapping of central nervous system development. Proc. Natl Acad. Sci. USA 95, 334–339 (1998). (10.1073/pnas.95.1.334) / Proc. Natl Acad. Sci. USA by X Wen (1998)
Fambrough,D., McClure,K., Kazlauskas,A. & Lander,E. S. Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes. Cell 97, 727–741 (1999). (10.1016/S0092-8674(00)80785-0) / Cell by D Fambrough (1999)
Eisen,M. B., Spellman,P. T., Brown,P. O. & Botstein,D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl Acad. Sci. USA 95, 14863– 14868 (1998). (10.1073/pnas.95.25.14863) / Proc. Natl Acad. Sci. USA by MB Eisen (1998)
Gawantka,V. et al. Gene expression screening in Xenopus identifies molecular pathways, predicts gene function and provides a global view of embryonic patterning. Mech. Dev. 77, 95–141 (1998). (10.1016/S0925-4773(98)00115-4) / Mech. Dev. by V Gawantka (1998)
Niehrs,C. Gene-expression screens in vertebrate embryos: more than meets the eye. Genes Funct. 1, 229–231 (1997). (10.1046/j.1365-4624.1997.00022.x) / Genes Funct. by C Niehrs (1997)
Onichtchouk,D. et al. The Xvent-2 homeobox gene is part of the BMP-4 signaling pathway controling dorso–ventral patterning of Xenopus mesoderm. Development 122, 3045–3053 (1996). (10.1242/dev.122.10.3045) / Development by D Onichtchouk (1996)
Jen, W. -C., Gawantka,V., Pollet,N., Niehrs,C. & Kintner,C. Periodic repression of Notch pathway genes governs the segmentation of Xenopus embryos. Genes Dev. 13, 1486–1499 (1999). (10.1101/gad.13.11.1486) / Genes Dev. by Jen, W. -C. (1999)
Dandekar,T., Snel,B., Huynen,M. & Bork,P. Conservation of gene order: a fingerprint of proteins that physically interact. Trends Biochem. Sci. 273, 324–328 (1998). (10.1016/S0968-0004(98)01274-2) / Trends Biochem. Sci. by T Dandekar (1998)
Jacob,F. The operon—25 years later. C. R. Acad. Sci. Paris 320, 199–206 (1997). (10.1016/S0764-4469(97)86927-2) / C. R. Acad. Sci. Paris by F Jacob (1997)
Lawrence,J. G. Selfish operons and speciation by gene transfer. Trends Microbiol. 5, 355–359 ( 1997). (10.1016/S0966-842X(97)01110-4) / Trends Microbiol. by JG Lawrence (1997)
Blattner,F. R. et al. The complete genome sequence of Escherichia coli K-12. Science 277, 1453–1474 ( 1997). (10.1126/science.277.5331.1453) / Science by FR Blattner (1997)
Blumenthal,T. Gene clusters and polycistronic transcription in eukaryotes. BioEssays 20, 480–487 ( 1998). (10.1002/(SICI)1521-1878(199806)20:6<480::AID-BIES6>3.0.CO;2-Q) / BioEssays by T Blumenthal (1998)
McInerny,C. J., Partridge,J. F., Mikesell,G. E., Creemer,D. P. & Breeden,L. L. A novel Mcm1-dependent element in the SWI4, CLN3, CDC6, and CDC47 promoters activates M/G1-specific transcription. Genes Dev. 11, 1277–1288 (1997). (10.1101/gad.11.10.1277) / Genes Dev. by CJ McInerny (1997)
Yuh,C. H., Bolouri,H. & Davidson,E. H. Genomic cis-regulatory logic: experimental and computational analysis of a sea urchin gene. Science 279, 1896–1902 (1998). (10.1126/science.279.5358.1896) / Science by CH Yuh (1998)
Britten,R. J. & Davidson,E. H. Gene regulation for higher cells: a theory. Science 165, 349– 357 (1969). (10.1126/science.165.3891.349) / Science by RJ Britten (1969)
Gerhart,J. & Kirschner,M. Cells, Embryos and Evolution (Blackwell, Malden, 1997). / Cells, Embryos and Evolution by J Gerhart (1997)
Duboule,D. & Wilkins,A. S. The evolution of ’bricolage’. Trends Genet. 14, 54–59 (1998). (10.1016/S0168-9525(97)01358-9) / Trends Genet. by D Duboule (1998)
Huang,F. Syntagms in development and evolution. Int. J. Dev. Biol. 42, 487–494 (1998). / Int. J. Dev. Biol. by F Huang (1998)
Jan,Y. N. & Jan,L. Y. Functional gene cassettes in development. Proc. Natl Acad. Sci. USA 90, 8305– 8307 (1993). (10.1073/pnas.90.18.8305) / Proc. Natl Acad. Sci. USA by YN Jan (1993)
Nishida,E. & Gotoh,Y. The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem. Sci. 18, 128–131 ( 1993). (10.1016/0968-0004(93)90019-J) / Trends Biochem. Sci. by E Nishida (1993)
Cheverud,J. M. Developmental integration and the evolution of pleiotropy. Am. Zool. 36, 44–50 ( 1996). (10.1093/icb/36.1.44) / Am. Zool. by JM Cheverud (1996)
Shubin,N., Tabin,C. & Carroll,S. Fossils, genes and the evolution of animal limbs. Nature 388, 639–648 ( 1997). (10.1038/41710) / Nature by N Shubin (1997)
Artavanis-Tsakonas,S., Rand,M. D. & Lake,R. J. Notch signaling: cell fate control and signal integration in development. Science 284, 770– 776 (1999). (10.1126/science.284.5415.770) / Science by S Artavanis-Tsakonas (1999)
Lagna,G., Hata,A., Hemmati-Brivanlou,A. & Massague,J. Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature 383, 832–836 (1996). (10.1038/383832a0) / Nature by G Lagna (1996)
Meersman, G. et al. The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in vivo and transcriptional activation. Mech. Develop. 61, 127–140 ( 1997). (10.1016/S0925-4773(96)00629-6) / Mech. Develop. by G Meersman (1997)
Bhushan,A., Chen,Y. & Vale,W. SMAD7 inhibits mesoderm formation and promotes neural cell fate in Xenopus embryos. Dev. Biol. 200, 260– 268 (1998). (10.1006/dbio.1998.8965) / Dev. Biol. by A Bhushan (1998)
Frisch,A. & Wright,C. V. E. XBMPRII, a novel Xenopus type II receptor mediating BMP signalling in embryonic tissues. Development 125, 431–442 (1998). (10.1242/dev.125.3.431) / Development by A Frisch (1998)
Hata,A., Lagna,G., Massague,J. & Hemmati-Brivanlou,A. SMAD6 inhibits BMP/SMAD1 signaling by specifically competing with the SMAD4 tumor suppressor. Genes Dev. 12, 186– 197 (1998). (10.1101/gad.12.2.186) / Genes Dev. by A Hata (1998)
Onichtchouk,D. et al. Silencing of TGF-β signalling by the pseudoreceptor BAMBI. Nature 400, 480–485 (1999). (10.1038/46794) / Nature by D Onichtchouk (1999)
Wagner,G. P. in Advances in Artificial Life (eds Moran, F., Moreno, A., Merelo, J. J. & Chacon, P. ) 317–328 (Springer, Berlin, 1995). / Advances in Artificial Life by GP Wagner (1995)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:41 a.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 8:57 a.m.)
Indexed	2 months, 2 weeks ago (June 12, 2025, 11:14 a.m.)
Issued	25 years, 9 months ago (Dec. 1, 1999)
Published	25 years, 9 months ago (Dec. 1, 1999)
Published Print	25 years, 9 months ago (Dec. 1, 1999)

Funders 0

None

BibTeX

@article{Niehrs_1999, title={Synexpression groups in eukaryotes}, volume={402}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/990025}, DOI={10.1038/990025}, number={6761}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Niehrs, Christof and Pollet, Nicolas}, year={1999}, month=dec, pages={483–487} }

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