Crossref journal-article
Springer Science and Business Media LLC
Nature Biotechnology (297)
Bibliography

Blaskovich, M. A., Lin, Q., Delarue, F. L., Sun, J., Park, H. S., Coppola, D., Hamilton, A. D., & Sebti, S. M. (2000). Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice. Nature Biotechnology, 18(10), 1065–1070.

Authors 8
  1. Michelle A. Blaskovich (first)
  2. Qing Lin (additional)
  3. Frederic L. Delarue (additional)
  4. Jiazhi Sun (additional)
  5. Hyung Soon Park (additional)
  6. Domenico Coppola (additional)
  7. Andrew D. Hamilton (additional)
  8. Saïd M. Sebti (additional)
References 33 Referenced 124
  1. Heldin, C.H., Ostman, A. & Ronnstrand, L. Signal transduction via platelet-derived growth factor receptors. Biochim. Biophys. Acta 1378, F79–F113 (1998). / Biochim. Biophys. Acta by CH Heldin (1998)
  2. Heldin, C.H. & Westermark, B. In The molecular and cellular biology of wound repair. Edn. 2 (Plenum Press, New York; 1996). / The molecular and cellular biology of wound repair by CH Heldin (1996)
  3. Raines, E.W., Bowen-Pope, D.F. & Ross, R. Platelet-derived growth factor. In Handbook of experimental pharmacology. Peptide growth factors and their receptors. (Springer, Heidelberg; 1990). / Handbook of experimental pharmacology. Peptide growth factors and their receptors by EW Raines (1990)
  4. Forsberg, K., Valyi-Nagy, I., Heldin, C.H., Herlyn, M. & Westermark, B. Platelet-derived growth factor (PDGF) in oncogenesis: development of vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB. Proc. Natl. Acad. Sci. USA 90, 393–397 (1993). (10.1073/pnas.90.2.393) / Proc. Natl. Acad. Sci. USA by K Forsberg (1993)
  5. Battegay, E.J., Rupp, J., Iruela-Arispe, L., Sage, E.H. & Pech, M. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors. J. Cell. Biol. 125, 917–928 (1994). (10.1083/jcb.125.4.917) / J. Cell. Biol. by EJ Battegay (1994)
  6. Thommen, R. et al. PDGF-BB increases endothelial migration on cord movements during angiogenesis in vitro. J. Cell. Biochem. 64, 403–413 (1997). (10.1002/(SICI)1097-4644(19970301)64:3<403::AID-JCB7>3.0.CO;2-Z) / J. Cell. Biochem. by R Thommen (1997)
  7. Kumar, R., Yoneda, J., Bucana, C.D. & Fidler, I.J. Regulation of distinct steps of angiogenesis by different angiogenic molecules. Int. J. Oncol. 12, 749–757 (1998). / Int. J. Oncol. by R Kumar (1998)
  8. Wang, D., Huang, H.J., Kazlauskas, A. & Cavenee, W.K. Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase. Cancer Res. 59, 1464–1472 (1999). / Cancer Res. by D Wang (1999)
  9. Leveen, P. et al. Mice deficient for PDGF-B show renal, cardiovascular and hematological abnormalities. Genes Dev. 8, 1875–1887 (1994). (10.1101/gad.8.16.1875) / Genes Dev. by P Leveen (1994)
  10. Soriano, P. Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. Genes Dev. 8, 1888–1896 (1994). (10.1101/gad.8.16.1888) / Genes Dev. by P Soriano (1994)
  11. Kazlauskas, A. & Cooper, J.A. Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins. Cell 58, 1121–1133 (1989). (10.1016/0092-8674(89)90510-2) / Cell by A Kazlauskas (1989)
  12. Lowenstein, E.J. et al. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell 70, 431–442 (1992). (10.1016/0092-8674(92)90167-B) / Cell by EJ Lowenstein (1992)
  13. Ramakrishnan, V. et al. A novel monoclonal antibody dependent on domain 5 of the platelet-derived growth factor beta receptor inhibits ligand binding and receptor activation. Growth Factors 8, 253–265 (1993). (10.3109/08977199308991571) / Growth Factors by V Ramakrishnan (1993)
  14. Engstrom, U., Engstrom, A., Ernlund, A., Westermark, B. & Heldin, C.H. Identification of a peptide antagonist for platelet-derived growth factor. J. Biol. Chem. 267, 16581–16587 (1992). (10.1016/S0021-9258(18)42042-X) / J. Biol. Chem. by U Engstrom (1992)
  15. Brennand, D.M. et al. Identification of a cyclic peptide inhibitor of platelet-derived growth factor-BB receptor-binding and mitogen-induced DNA synthesis in human fibroblasts. FEBS Lett. 413, 70–74 (1997). (10.1016/S0014-5793(97)00885-5) / FEBS Lett. by DM Brennand (1997)
  16. Shulman, T., Sauer, F.G., Jackman, R.M., Chang, C.N. & Landolfi, N.F. An antibody reactive with domain 4 of the platelet-derived growth factor β receptor allows BB binding while inhibiting proliferation by impairing receptor dimerization. J. Biol. Chem. 272, 17400–17404 (1997). (10.1074/jbc.272.28.17400) / J. Biol. Chem. by T Shulman (1997)
  17. Klohs, W.D., Fry, D.W. & Kraker, A.J. Inhibitors of tyrosine kinase. Curr. Opin. Oncol. 9, 562–568 (1997). (10.1097/00001622-199711000-00012) / Curr. Opin. Oncol. by WD Klohs (1997)
  18. Levitzki, A. & Gazit, A. Tyrosine kinase inhibition: an approach to drug development. Science 267, 1782–1788 (1995). (10.1126/science.7892601) / Science by A Levitzki (1995)
  19. Ferns, G.A. et al. Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science 253, 1129–1132 (1991). (10.1126/science.1653454) / Science by GA Ferns (1991)
  20. Duan, D.S., Pazin, M.J., Fretto, L.J. & Williams, L.T. A functional soluble extracellular region of the platelet-derived growth factor (PDGF) β receptor antagonizes PDGF-stimulated responses. J. Biol. Chem. 266, 413–418 (1991). (10.1016/S0021-9258(18)52450-9) / J. Biol. Chem. by DS Duan (1991)
  21. Green, L.S. et al. Inhibitory DNA ligands to platelet-derived growth factor B-chain. Biochemistry 35, 14413–14424 (1996). (10.1021/bi961544+) / Biochemistry by LS Green (1996)
  22. Park, H.D., Lin, Q. & Hamilton, A.D. Protein surface recognition by synthetic receptors: a route to novel sub-micromolar inhibitors for chymotrypsin. J. Am. Chem. Soc. 121, 8–13 (1999). (10.1021/ja981504o) / J. Am. Chem. Soc. by HD Park (1999)
  23. Hamuro, Y., Calama, M.C., Park, H.S. & Hamilton, A.D. A calixarene with four peptide loops: an antibody mimic for recognition of protein surfaces. Angew. Chem. Int. Edn. Engl. 36, 2680–2683 (1997). (10.1002/anie.199726801) / Angew. Chem. Int. Edn. Engl. by Y Hamuro (1997)
  24. Oefner, C., Arey, A.D., Winkler, F.K., Eggimann, B. & Hosang, M. Crystal structure of human platelet derived growth factor, EMBO J. 11, 3921–3926 (1996). (10.1002/j.1460-2075.1992.tb05485.x) / EMBO J. by C Oefner (1996)
  25. Anderson, M. et al. Involvement of loop 2 of platelet derived growth factor-AA and -BB in receptor binding. Growth Factors 12, 159–164 (1995). (10.3109/08977199509028962) / Growth Factors by M Anderson (1995)
  26. Muller, Y.A. et al. Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site. Proc. Natl. Acad. Sci. USA 94, 7192–7197, 1997. (10.1073/pnas.94.14.7192) / Proc. Natl. Acad. Sci. USA by YA Muller (1997)
  27. Campion, S.R. & Niyogi, S.K. Interaction of the epidermal growth factor with its receptor. Prog. Nucleic Acid Res. Mol. Biol. 49, 353–383 (1994). (10.1016/S0079-6603(08)60055-0) / Prog. Nucleic Acid Res. Mol. Biol. by SR Campion (1994)
  28. Stauber, D.J., DiGabriele, A.D. & Hendrickson, W.A. Structural interactions of fibroblast growth factor receptor with its ligands. Proc. Natl. Acad. Sci. USA 97, 49–54 (2000). (10.1073/pnas.97.1.49) / Proc. Natl. Acad. Sci. USA by DJ Stauber (2000)
  29. McInnes, C. & Sykes, B.D. Growth factor receptors: structure, mechanism and drug discovery. Biopolymers 43, 339–366 (1997). (10.1002/(SICI)1097-0282(1997)43:5<339::AID-BIP2>3.0.CO;2-W) / Biopolymers by C McInnes (1997)
  30. Jones, J.T. et al. Binding interaction of the heregulinβ egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis. J. Biol. Chem. 273, 11667–11674 (1998). (10.1074/jbc.273.19.11667) / J. Biol. Chem. by JT Jones (1998)
  31. McGuire, T., Qian, Y., Hamilton, A.D. & Sebti, S.M. Platelet derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation and not farnesylation. J. Biol. Chem. 271, 27402–27407 (1996). (10.1074/jbc.271.44.27402) / J. Biol. Chem. by T McGuire (1996)
  32. Sun, J. et al. Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: combination therapy with the cytotoxic agents cisplatin, taxol and gemcitabine. Cancer Res. 59, 4919–4926 (1999). / Cancer Res. by J Sun (1999)
  33. Weidner, N., Semple, J.P., Welch, W.R. & Folkman, J. Tumor angiogenesis and metastasis—correlation in invasive breast carcinoma. N. Engl. J. Med. 324, 1–8 (1991). (10.1056/NEJM199101033240101) / N. Engl. J. Med. by N Weidner (1991)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:35 a.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 3:31 p.m.)
Indexed 3 months, 1 week ago (May 22, 2025, 2:46 a.m.)
Issued 24 years, 11 months ago (Oct. 1, 2000)
Published 24 years, 11 months ago (Oct. 1, 2000)
Published Print 24 years, 11 months ago (Oct. 1, 2000)
Funders 0

None

@article{Blaskovich_2000, title={Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice}, volume={18}, ISSN={1546-1696}, url={http://dx.doi.org/10.1038/80257}, DOI={10.1038/80257}, number={10}, journal={Nature Biotechnology}, publisher={Springer Science and Business Media LLC}, author={Blaskovich, Michelle A. and Lin, Qing and Delarue, Frederic L. and Sun, Jiazhi and Park, Hyung Soon and Coppola, Domenico and Hamilton, Andrew D. and Sebti, Saïd M.}, year={2000}, month=oct, pages={1065–1070} }