Exploiting recombination in single bacteria to make large phage antibody libraries
10.1038/71958
Crossref journal-article
Springer Science and Business Media LLC
Nature Biotechnology (297)
Bibliography

Sblattero, D., & Bradbury, A. (2000). Exploiting recombination in single bacteria to make large phage antibody libraries. Nature Biotechnology, 18(1), 75–80.

Authors 2
  1. Daniele Sblattero (first)
  2. Andrew Bradbury (additional)
References 29 Referenced 244
  1. Barbas, C.F., Kang, A.S., Lerner, R.A. & Benkovic, S.J. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc. Natl. Acad. Sci. USA 88, 7978– 7982 (1991). (10.1073/pnas.88.18.7978) / Proc. Natl. Acad. Sci. USA by CF Barbas (1991)
  2. Griffiths, A.D. et al. Human anti-self antibodies with high specificity from phage display libraries. EMBO J. 12, 725– 734 (1993). (10.1002/j.1460-2075.1993.tb05706.x) / EMBO J by AD Griffiths (1993)
  3. Griffiths, A.D. et al. Isolation of high affinity human antibodies directly from large synthetic repertoires EMBO J. 13, 3245–3260 (1994). (10.1002/j.1460-2075.1994.tb06626.x) / EMBO J. by AD Griffiths (1994)
  4. Marks, J.D. et al. By-passing immunization: building high affinity human antibodies by chain shuffling. Bio/Technology. 10, 779–783 (1992). / Bio/Technology by JD Marks (1992)
  5. Nissim, A. et al. Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents. EMBO J. 13, 692–698 (1994). (10.1002/j.1460-2075.1994.tb06308.x) / EMBO J by A Nissim (1994)
  6. Perelson, A.S. & Oster, G.F. Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self non-self discrimination . J. Theor. Biol. 81, 645– 670 (1979). (10.1016/0022-5193(79)90275-3) / J. Theor. Biol. by AS Perelson (1979)
  7. Vaughan, T.J. et al. Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nat. Biotechnol. 14, 309–314 (1996). (10.1038/nbt0396-309) / Nat. Biotechnol. by TJ Vaughan (1996)
  8. de Haard, H.J. et al. A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies. J. Biol. Chem. 274, 18218–18230 (1999). (10.1074/jbc.274.26.18218) / J. Biol. Chem by HJ de Haard (1999)
  9. Sheets, M.D. et al. Efficient construction of a large nonimmune phage antibody library; the production of panels of high affinity human single-chain antibodies to protein antigens. Proc. Natl. Acad. Sci. USA 95, 6157–6162 (1998). (10.1073/pnas.95.11.6157) / Proc. Natl. Acad. Sci. USA by MD Sheets (1998)
  10. Geoffroy, F., Sodoyer, R. & Aujame, L. A new phage display system to construct multicombinatorial libraries of very large antibody repertoires. Gene 151, 109–113 (1994). (10.1016/0378-1119(94)90639-4) / Gene by F Geoffroy (1994)
  11. Tsurushita, N., Fu, H. & Warren, C. Phage display vectors for in vivo recombination if immunoglobulin heavy and light chain genes to make large combinatorial libraries. Gene 172, 59–63 (1996). (10.1016/0378-1119(96)00170-9) / Gene by N Tsurushita (1996)
  12. Waterhouse, P., Griffiths, A.D., Johnson, K.S. & Winter, G. Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires. Nucleic Acids Res. 21, 2265–2266. (1993). (10.1093/nar/21.9.2265) / Nucleic Acids Res by P Waterhouse (1993)
  13. Hoess, R., Wierzbicki, A. & Abremiski, K. The role of the loxP spacer region in P1 site-specific recombination. Nucleic Acids Res. 14, 2287 –2300 (1986). (10.1093/nar/14.5.2287) / Nucleic Acids Res by R Hoess (1986)
  14. Mariuzza, R.A. et al. Preliminary crystallographic study of the complex between the Fab fragment of a monoclonal anti-lysozyme antibody and its antigen. J. Mol. Biol. 170, 1055–1058 (1983). (10.1016/S0022-2836(83)80206-X) / J. Mol. Biol by RA Mariuzza (1983)
  15. Furth, M.E., Davis, L.J., Fleurdelys, B. & Scolnic, E.M. Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family. J. Virol. 43, 294–304 ( 1982). (10.1128/JVI.43.1.294-304.1982) / J. Virol. by ME Furth (1982)
  16. Holliger, P., Prospero, T. & Winter, G. “Diabodies”: small bivalent and bispecific antibody fragments. Proc. Natl. Acad. Sci. USA. 90, 6444–6448 (1993). (10.1073/pnas.90.14.6444) / Proc. Natl. Acad. Sci. USA by P Holliger (1993)
  17. Tomlinson, I.M., Williams, S.C., Corbett, S.J., Cox, J.P.L. & Winter, G. VBASE sequence directory.(MRC Centre for Protein Engineering, Cambridge, UK; 1996) http://www.mrc-cpe.cam.ac.uk/imt-doc/vbase-home-page.html .
  18. de Kruif, J., Boel, E. & Logtenberg, T. Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions. J. Mol. Biol. 248, 97– 105 (1995). (10.1006/jmbi.1995.0204) / J. Mol. Biol. by J de Kruif (1995)
  19. Marks, J.D. et al. By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol. 222, 581 –597 (1991). (10.1016/0022-2836(91)90498-U) / J. Mol. Biol. by JD Marks (1991)
  20. Sambrook, J., Fritsch, E.F. & Maniatis, T. Molecular cloning: a laboratory manual(Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY; 1989).
  21. de Bruin, R., Spelt, K., Mol, J., Koes, R. & Quattrocchio, F. Selection of high-affinity phage antibodies from phage display libraries Nat. Biotechnol.. 17, 397–399 (1999). (10.1038/7959) / Nat. Biotechnol by R de Bruin (1999)
  22. Sblattero, D. & Bradbury, A. A definitive set of oligonucleotide primers for amplifying human V regions. Immunotechnology 3, 271–278 (1998). (10.1016/S1380-2933(97)10004-5) / Immunotechnology by D Sblattero (1998)
  23. Schier, R. & Marks, J.D. Efficient in vitro affinity maturation of phage antibodies using BIAcore guided selections. Hum. Antib. Hybrid. 7, 97–105. ( 1996). (10.3233/HAB-1996-7302) / Hum. Antib. Hybrid by R Schier (1996)
  24. Clackson, T. & Wells, J.A. In vitro selection from protein and peptide libraries. Trends Biotechnol. 12, 173–184. (1994). (10.1016/0167-7799(94)90079-5) / Trends Biotechnol. by T Clackson (1994)
  25. Schier, R. et al. Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection. J. Mol. Biol. 255, 28–43 (1996). (10.1006/jmbi.1996.0004) / J. Mol. Biol. by R Schier (1996)
  26. Sauer, B. & Henderson, N. The cyclization of linear DNA in Escherichia coli by site-specific recombination. Gene . 70, 331–341 ( 1988). (10.1016/0378-1119(88)90205-3) / Gene by B Sauer (1988)
  27. Hanke, T., Szawlowski, P. & Randall, R.E. Construction of solid matrix-antibody-antigen complexes containing simian immunodeficiency virus p27 using tag-specific monoclonal antibody and tag-linked antigen. J. Gen. Virol. 73, 653–660 (1992). (10.1099/0022-1317-73-3-653) / J. Gen. Virol. by T Hanke (1992)
  28. Werge, T.M., Bradbury, A., Di Luzio, A. & Cattaneo, A. A recombinant cell line, expressing a form of the anti-p21ras antibody, Y13-259, which binds protein A and may be produced as ascites. Oncogene 7, 1033–1035 ( 1992). / Oncogene by TM Werge (1992)
  29. Krebber, A. et al . Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system. J. Immunol. Methods 201, 35–55 (1997). (10.1016/S0022-1759(96)00208-6) / J. Immunol. Methods by A Krebber (1997)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:48 a.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 3:17 p.m.)
Indexed 6 days, 17 hours ago (Aug. 27, 2025, 12:07 p.m.)
Issued 25 years, 8 months ago (Jan. 1, 2000)
Published 25 years, 8 months ago (Jan. 1, 2000)
Published Print 25 years, 8 months ago (Jan. 1, 2000)
Funders 0

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@article{Sblattero_2000, title={Exploiting recombination in single bacteria to make large phage antibody libraries}, volume={18}, ISSN={1546-1696}, url={http://dx.doi.org/10.1038/71958}, DOI={10.1038/71958}, number={1}, journal={Nature Biotechnology}, publisher={Springer Science and Business Media LLC}, author={Sblattero, Daniele and Bradbury, Andrew}, year={2000}, month=jan, pages={75–80} }