DOI: 10.1038/71600. Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas

10.1038/71600

Crossref journal-article

Springer Science and Business Media LLC

Nature Medicine (297)

Bibliography

Higashitsuji, H., Itoh, K., Nagao, T., Dawson, S., Nonoguchi, K., Kido, T., Mayer, R. J., Arii, S., & Fujita, J. (2000). Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas. Nature Medicine, 6(1), 96â99.

Authors 9

Hiroaki Higashitsuji (first)
Katsuhiko Itoh (additional)
Toshikazu Nagao (additional)
Simon Dawson (additional)
Kohsuke Nonoguchi (additional)
Tsuneo Kido (additional)
R. John Mayer (additional)
Shigeki Arii (additional)
Jun Fujita (additional)

References 20 Referenced 254

Hsu, I.C., et al. Mutational hotspot in the p53 gene in human hepatocellular carcinomas . Nature 350, 427–428 (1991). (10.1038/350427a0) / Nature by IC Hsu (1991)
Bressac, B., Kew, M., Wands, J. & Ozturk, M. Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa. Nature 350, 429–431 ( 1991). (10.1038/350429a0) / Nature by B Bressac (1991)
Liew, et al. High frequency of p16INK4A gene alterations in hepatocellular carcinoma . Oncogene 18, 789–795 (1999). (10.1038/sj.onc.1202359) / Oncogene by Liew (1999)
Higuchi, T., et al. Induction of tissue inhibitor of metalloproteinase 3 gene expression during in vitro decidualization of human endometrial stromal cells. Endocrinology 136, 4973– 4981 (1995). (10.1210/endo.136.11.7588231) / Endocrinology by T Higuchi (1995)
Hori, T., et al. cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome. Gene 216, 113–122 ( 1998). (10.1016/S0378-1119(98)00309-6) / Gene by T Hori (1998)
Dawson, S., et al. The 26S-proteasome: regulation and substrate recognition. Mol. Biol. Rep. 24, 39–44 (1997). (10.1023/A:1006800522814) / Mol. Biol. Rep. by S Dawson (1997)
Nevins, J.R., Leone, G., DeGregori, J. & Jakoi, L. Role of the Rb/E2F pathway in cell growth control. J. Cell. Physiol. 173 , 233–236 (1997). (10.1002/(SICI)1097-4652(199711)173:2<233::AID-JCP27>3.0.CO;2-F) / J. Cell. Physiol. by JR Nevins (1997)
Weinberg, R.A. the retinoblastoma protein and cell cycle control. Cell 81, 323–330 (1995). (10.1016/0092-8674(95)90385-2) / Cell by RA Weinberg (1995)
Chen, Y., Sharp, Z.D. & Lee, W.H. HEC binds to the seventh regulatory subunitof the 26S proteasome and modulates the proteolysis of mitotic cyclins. J. Biol. Chem. 272, 24081–24087 (1997). (10.1074/jbc.272.38.24081) / J. Biol. Chem. by Y Chen (1997)
Mahaffey, D. & Rechsteiner, M. Discrimination between ubiquitin-dependent and ubiquitin-independent proteolytic pathways by the 26S proteasome subunit 5a. FEBS Lett. 450, 123–125 ( 1999). (10.1016/S0014-5793(99)00456-1)
Kisselev, A.F., Akopian, T., Woo, K.M. & Goldberg, A.L. The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation. J. Biol. Chem. 274, 3363–3371 (1999). (10.1074/jbc.274.6.3363) / J. Biol. Chem. by AF Kisselev (1999)
Woitach, J.T., Zhang, M., Niu, C.H. & Thorgeirsson, S.S. A retinoblastoma- binding protein that affects cell-cycle control and confers transforming ability . Nature Genet. 19, 371– 374 (1998). (10.1038/1258) / Nature Genet. by JT Woitach (1998)
Johnson, D.G., Schneider-Broussard, R. Role of E2F in cell cycle control and cancer. Front. Biosci. 3, d447–448 (1998). (10.2741/A291) / Front. Biosci. by DG Johnson (1998)
Israel, A. IkB kinase all zipped up. Nature 388, 519 –521 (1997). / Nature by A Israel (1997)
Ciechanover, A., et al. The ubiquitin-mediated proteolytic system: involvement of molecular chaperones, degradation of oncoproteins, and activation of transcriptional regulators. Cold Spring Harb. Symp. Quant. Biol. 60 , 491–501 (1995). (10.1101/SQB.1995.060.01.053) / Cold Spring Harb. Symp. Quant. Biol. by A Ciechanover (1995)
Spataro, V., Norbury, C. & Harris, A.L. The ubiquitin-proteasome pathway in cancer. Br. J. Cancer 77, 448–455 (1998). (10.1038/bjc.1998.71) / Br. J. Cancer by V Spataro (1998)
Scheffner, M., Huibregtse, J.M., Vierstra, R.D. & Howley, P.M. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75, 495– 505 (1993). (10.1016/0092-8674(93)90384-3) / Cell by M Scheffner (1993)
Boyer, S.N., Wazer, D.E. & Band, V. E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway. Cancer Res. 56, 4620–4624 (1996). / Cancer Res. by SN Boyer (1996)
Berezutskaya, E. & Bagchi, S. The human papillomavirus E7 oncoprotein functionally interacts with the S4 subunit of the 26S proteasome . J. Biol. Chem. 272, 30135– 30140 (1997). (10.1074/jbc.272.48.30135) / J. Biol. Chem. by E Berezutskaya (1997)
Smith-McCune, K., et al. Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130. Proc. Natl. Acad. Sci. USA 96, 6999–7004 (1999). (10.1073/pnas.96.12.6999) / Proc. Natl. Acad. Sci. USA by K Smith-McCune (1999)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:34 a.m.)
Deposited	2 years, 3 months ago (May 18, 2023, 7:10 p.m.)
Indexed	1 week, 1 day ago (Aug. 26, 2025, 2:30 a.m.)
Issued	25 years, 8 months ago (Jan. 1, 2000)
Published	25 years, 8 months ago (Jan. 1, 2000)
Published Print	25 years, 8 months ago (Jan. 1, 2000)

Funders 0

None

BibTeX

@article{Higashitsuji_2000, title={Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas}, volume={6}, ISSN={1546-170X}, url={http://dx.doi.org/10.1038/71600}, DOI={10.1038/71600}, number={1}, journal={Nature Medicine}, publisher={Springer Science and Business Media LLC}, author={Higashitsuji, Hiroaki and Itoh, Katsuhiko and Nagao, Toshikazu and Dawson, Simon and Nonoguchi, Kohsuke and Kido, Tsuneo and Mayer, R. John and Arii, Shigeki and Fujita, Jun}, year={2000}, month=jan, pages={96–99} }

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