Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle
10.1038/43694
Crossref journal-article
Springer Science and Business Media LLC
Nature (297)
Bibliography

Seto, A. G., Zaug, A. J., Sobel, S. G., Wolin, S. L., & Cech, T. R. (1999). Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle. Nature, 401(6749), 177–180.

Authors 5
  1. Anita G. Seto (first)
  2. Arthur J. Zaug (additional)
  3. Suzanne G. Sobel (additional)
  4. Sandra L. Wolin (additional)
  5. Thomas R. Cech (additional)
References 28 Referenced 223
  1. Bodnar,A. G. et al. Extension of life-span by introduction of telomerase into normal human cells. Science 279, 349–352 (1998). (10.1126/science.279.5349.349) / Science by AG Bodnar (1998)
  2. Kim,N. W. et al. Specific association of human telomerase activity with immortal cells and cancer. Science 266, 2011–2103 (1994). (10.1126/science.7605428) / Science by NW Kim (1994)
  3. Greider,C. W. & Blackburn,E. H. A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337, 331–337 (1989). (10.1038/337331a0) / Nature by CW Greider (1989)
  4. Lingner,J. et al. Reverse transcriptase motifs in the catalytic subunit of telomerase. Science 276, 561–567 (1997). (10.1126/science.276.5312.561) / Science by J Lingner (1997)
  5. Bryan,T. M. & Cech,T. R. Telomerase and the maintenance of chromosome ends. Curr. Opin. Cell Biol. 11, 318–324 (1999). (10.1016/S0955-0674(99)80043-X) / Curr. Opin. Cell Biol. by TM Bryan (1999)
  6. Nugent,C. I. & Lundblad,V. The telomerase reverse transcriptase: components and regulation. Genes Dev. 12, 1073–1085 (1998). (10.1101/gad.12.8.1073) / Genes Dev. by CI Nugent (1998)
  7. Singer,M. S. & Gottschling,D. E. TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266, 404–409 (1994). (10.1126/science.7545955) / Science by MS Singer (1994)
  8. Lührmann,R., Kastner,B. & Bach,M. Structure of spliceosomal snRNPs and their role in pre-mRNA splicing. Biochim. Biophys. Acta 1087, 265–292 (1990). (10.1016/0167-4781(90)90001-I) / Biochim. Biophys. Acta by R Lührmann (1990)
  9. Mattaj,I. W. Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding. Cell 46, 905–911 (1986). (10.1016/0092-8674(86)90072-3) / Cell by IW Mattaj (1986)
  10. Chapon,C., Cech,T. R. & Zaug,A. J. Polyadenylation of telomerase RNA in budding yeast. RNA 3, 1337–1351 (1997). / RNA by C Chapon (1997)
  11. Yu, Y.-T., Scharl,E. C., Smith,C. M. & Steitz,J. A. in The RNA World (eds Gesteland, R. F., Cech, T. R. & Atkins, J. F.) 487–524 (Cold Spring Harbor Lab. Press, Cold Spring Harbor, New York, 1999). / The RNA World by Yu, Y.-T. (1999)
  12. Jones,M. H. & Guthrie,C. Unexpected flexibility in an evolutionarily conserved protein–RNA interaction: genetic analysis of the Sm binding site. EMBO J. 9, 2555–2561 (1990). (10.1002/j.1460-2075.1990.tb07436.x) / EMBO J. by MH Jones (1990)
  13. Lendvay,T. S., Morris,D. K., Sah,J., Balasubramanian,B. & Lundblad,V. Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. Genetics 144, 1399–1412 (1996). (10.1093/genetics/144.4.1399) / Genetics by TS Lendvay (1996)
  14. Roy,J., Zheng,B., Rymond,B. C. & Woolford, J. L. Jr Structurally related but functionally distinct yeast Sm D core small nuclear ribonucleoprotein particle proteins. Mol. Cell. Biol. 15, 445–455 (1995). (10.1128/MCB.15.1.445) / Mol. Cell. Biol. by J Roy (1995)
  15. Pettersson,I., Hinterberger,M., Mimori,T., Gottlieb,E. & Steitz,J. A. The structure of mammalian small nuclear ribonucleoproteins: identification of multiple protein components reactive with anti-(U1)RNP and anti-Sm autoantibodies. J. Biol. Chem. 259, 5907–5914 (1984). (10.1016/S0021-9258(18)91101-4) / J. Biol. Chem. by I Pettersson (1984)
  16. Neubauer G. et al. Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry. Proc. Natl Acad. Sci. USA 94, 385–390 (1997). (10.1073/pnas.94.2.385) / Proc. Natl Acad. Sci. USA by Neubauer G. (1997)
  17. Cohn,M. & Blackburn,E. H. Telomerase in yeast. Science 269, 396–400 (1995). (10.1126/science.7618104) / Science by M Cohn (1995)
  18. Prescott,J. & Blackburn,E. H. Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro. Genes Dev. 11, 528–540 (1997). (10.1101/gad.11.4.528) / Genes Dev. by J Prescott (1997)
  19. Seipelt,R. L., Zhang,B., Asuru,A. & Rymond,B. U1 snRNA is cleaved by RNase III and processed through an Sm site-dependent pathway. Nucleic Acids Res. 27, 587–595 (1999). (10.1093/nar/27.2.587) / Nucleic Acids Res. by RL Seipelt (1999)
  20. Elela,S. A. & Ares, M. Jr Depletion of yeast RNase III blocks correct U2 3′ end formation and results in polyadenylated but functional U2 snRNA. EMBO J. 17, 3738–3746 (1998). (10.1093/emboj/17.13.3738) / EMBO J. by SA Elela (1998)
  21. Kambach,C. et al. Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell 96, 375–387 (1999). (10.1016/S0092-8674(00)80550-4) / Cell by C Kambach (1999)
  22. Mitchell,J. R., Cheng,J. & Collins,K. A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3′ end. Mol. Cell. Biol. 19, 567–576 (1999). (10.1128/MCB.19.1.567) / Mol. Cell. Biol. by JR Mitchell (1999)
  23. Mattaj,I. W. in Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles (ed. Birnstiel, M. L.) 100–114 (Springer, Berlin, 1988). (10.1007/978-3-642-73020-7_4) / Structure and Function of Major and Minor Small Nuclear Ribonucleoprotein Particles by IW Mattaj (1988)
  24. Virta-Pearlman,G., Morris,D. K. & Lundblad,V. Est1 has the properties of a single-stranded telomere end-binding protein. Genes Dev. 10, 3094–3104 (1996). (10.1101/gad.10.24.3094) / Genes Dev. by G Virta-Pearlman (1996)
  25. Rose,M. D., Winston,F. & Hieter,P. Methods in Yeast Genetics. A Laboratory Manual 177–186 (Cold Spring Harbor Lab. Press, Cold Spring Harbor, New York, 1990). / Methods in Yeast Genetics. A Laboratory Manual by MD Rose (1990)
  26. Schiestl,R. H. & Gietz,R. D. High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier. Curr. Genet. 16, 339–346 (1989). (10.1007/BF00340712) / Curr. Genet. by RH Schiestl (1989)
  27. Scherer,S. & Davis,R. W. Replacement of chromosome segments with altered DNA sequences constructed in vitro. Proc. Natl Acad. Sci. USA 76, 4951–4955 (1979). (10.1073/pnas.76.10.4951) / Proc. Natl Acad. Sci. USA by S Scherer (1979)
  28. Ey,P. L., Prowse,S. J. & Jenkin,C. R. Isolation of pure IgG1, IgG2a and IgG2b immunoglobins from mouse serum using Protein A-sepharose. Immunochemistry 15, 429–436 (1978). (10.1016/0161-5890(78)90070-6) / Immunochemistry by PL Ey (1978)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:41 a.m.)
Deposited 2 years, 3 months ago (May 17, 2023, 8:58 p.m.)
Indexed 1 month, 2 weeks ago (July 19, 2025, 11:48 p.m.)
Issued 26 years ago (Sept. 1, 1999)
Published 26 years ago (Sept. 1, 1999)
Published Print 26 years ago (Sept. 1, 1999)
Funders 0

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@article{Seto_1999, title={Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle}, volume={401}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/43694}, DOI={10.1038/43694}, number={6749}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Seto, Anita G. and Zaug, Arthur J. and Sobel, Suzanne G. and Wolin, Sandra L. and Cech, Thomas R.}, year={1999}, month=sep, pages={177–180} }