DOI: 10.1038/39369. Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

10.1038/39369

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Nakao, A., Afrakhte, M., Morn, A., Nakayama, T., Christian, J. L., Heuchel, R., Itoh, S., Kawabata, M., Heldin, N.-E., Heldin, C.-H., & Dijke, P. ten. (1997). Identification of Smad7, a TGFÎ²-inducible antagonist of TGF-Î² signalling. Nature, 389(6651), 631â635.

Authors 11

Atsuhito Nakao (first)
Mozhgan Afrakhte (additional)
Anita Morn (additional)
Takuya Nakayama (additional)
Jan L. Christian (additional)
Rainer Heuchel (additional)
Susumu Itoh (additional)
Masahiro Kawabata (additional)
Nils-Erik Heldin (additional)
Carl-Henrik Heldin (additional)
Peter ten Dijke (additional)

References 29 Referenced 1,539

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Zhang, Y., Feng, X.-H., Wu, R.-Y. & Derynck, R. Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature 383, 168–172 (1996). (10.1038/383168a0) / Nature by Y Zhang (1996)
Macías-Silva, M. et al. MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signalling. Cell 87, 1215–1224 (1996). (10.1016/S0092-8674(00)81817-6) / Cell by M Macías-Silva (1996)
Nakao, A. et al. TGF-β receptor mediated signalling through Smad2, Smad3 and Smad4. EMBO J. 16, 5353–5362 (1997). (10.1093/emboj/16.17.5353) / EMBO J. by A Nakao (1997)
Lagna, G., Hata, A., Hemmati-Brivanlou, A. & Massagué, J. Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature 383, 832–836 (1996). (10.1038/383832a0) / Nature by G Lagna (1996)
Zhang, Y., Musci, T. & Derynck, R. The tumor suppressor Smad4/DPC4 as a central mediator of Smad function. Curr. Biol. 7, 270–276 (1997). (10.1016/S0960-9822(06)00123-0) / Curr. Biol. by Y Zhang (1997)
Wu, R.-Y., Zhang, Y., Feng, X.-H. & Derynck, R. Heteromeric and homomeric interactions correlate with signalling activity and functional cooperativity of Smad3 and Smad4/DPC4. Mol. Cell. Biol. 17, 2521–2528 (1997). (10.1128/MCB.17.5.2521) / Mol. Cell. Biol. by R-Y Wu (1997)
Shi, Y., Hata, A., Lo, R. S., Massagué, J. & Pavletich, N. P. Astructural basis for mutational inactivation of the tumour suppressor Smad4. Nature 388, 87–93 (1997). (10.1038/40431) / Nature by Y Shi (1997)
Kretzschmar, M., Liu, F., Hata, A., Doody, J. & Massagué, J. The TGF-β family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Genes Dev. 11, 984–995 (1997). (10.1101/gad.11.8.984) / Genes Dev. by M Kretzschmar (1997)
Chen, X., Rubock, M. J. & Whitman, M. Atranscriptional partner for MAD proteins in TGF-β signalling. Nature 383, 691–696 (1996). (10.1038/383691a0) / Nature by X Chen (1996)
Kim, J., Johnson, K., Chen, H. J., Carrol, S. & Laughon, A. Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388, 304–308 (1997). (10.1038/40906) / Nature by J Kim (1997)
Imamura, T. et al. Smad6 inhibits signalling by the TGF-β superfamily. Nature 389, 622–626 (1997). (10.1038/39355) / Nature by T Imamura (1997)
Hemmati-Brivanlou, A. & Melton, D. Atruncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359, 609–614 (1992). (10.1038/359609a0) / Nature by A Hemmati-Brivanlou (1992)
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Smith, J. C., Price, B. M. J., Green, J. B., Weigel, D. & Herrman, B. G. Expression of a Xenopus homolog of Brachury (T) is an immediate-early response to mesoderm induction. Cell 67, 79–87 (1991). (10.1016/0092-8674(91)90573-H) / Cell by JC Smith (1991)
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Piccolo, S., Sasai, Y., Lu, B. & De Robertis, E. M. Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86, 589–598 (1996). (10.1016/S0092-8674(00)80132-4) / Cell by S Piccolo (1996)
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Dates

Type	When
Created	23 years ago (July 26, 2002, 4:37 a.m.)
Deposited	2 years, 3 months ago (May 17, 2023, 8:14 p.m.)
Indexed	2 days, 3 hours ago (Aug. 23, 2025, 12:58 a.m.)
Issued	27 years, 10 months ago (Oct. 1, 1997)
Published	27 years, 10 months ago (Oct. 1, 1997)
Published Print	27 years, 10 months ago (Oct. 1, 1997)

Funders 0

None

BibTeX

@article{Nakao_1997, title={Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling}, volume={389}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/39369}, DOI={10.1038/39369}, number={6651}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Nakao, Atsuhito and Afrakhte, Mozhgan and Morn, Anita and Nakayama, Takuya and Christian, Jan L. and Heuchel, Rainer and Itoh, Susumu and Kawabata, Masahiro and Heldin, Nils-Erik and Heldin, Carl-Henrik and Dijke, Peter ten}, year={1997}, month=oct, pages={631–635} }

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