DOI: 10.1038/387422a0. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F

10.1038/387422a0

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Leone, G., DeGregori, J., Sears, R., Jakoi, L., & Nevins, J. R. (1997). Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature, 387(6631), 422â426.

Authors 5

Gustavo Leone (first)
James DeGregori (additional)
Rosalie Sears (additional)
Laszlo Jakoi (additional)
Joseph R. Nevins (additional)

References 27 Referenced 354

Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell 81, 323–330 (1995). (10.1016/0092-8674(95)90385-2) / Cell by RA Weinberg (1995)
Sherr, C. J. & Roberts, J. M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9, 1149–1163 (1995). (10.1101/gad.9.10.1149) / Genes Dev. by CJ Sherr (1995)
Eisenman, R. N. & Cooper, J. A. Signal transduction: Beating a path to Myc. Nature 378, 438–439 (1995). (10.1038/378438a0) / Nature by RN Eisenman (1995)
Mulcahy, L. S., Smith, M. R. & Stacey, D. W. Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells. Nature 313, 241–243 (1985). (10.1038/313241a0) / Nature by LS Mulcahy (1985)
Lowry, D. R. & Willumsen, B. M. Function and regulation of ras. Annu. Rev. Biochem. 62, 851–891 (1993). (10.1146/annurev.bi.62.070193.004223) / Annu. Rev. Biochem. by DR Lowry (1993)
Feig, L. A. & Cooper, G. M. Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol. Cell. Biol. 8, 3235–3243 (1988). (10.1128/MCB.8.8.3235) / Mol. Cell. Biol. by LA Feig (1988)
Land, H., Parada, L. F. & Weinberg, R. A. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304, 596–602 (1982). (10.1038/304596a0) / Nature by H Land (1982)
Kohl, N. E. & Ruley, H. E. Role of c-myc in the transformation of REF52 cells by viral and cellular oncogenes. Oncogene 2, 41–48 (1987). / Oncogene by NE Kohl (1987)
Leone, G., DeGregori, J., Jakoi, L. & Nevins, J. R. Collaboration of E2F and cyclin E/cdk2 in the induction of S phase. Proc. Natl Acad. Sci. USA (submitted).
Hatekeyama, M., Brill, J. A., Fink, G. R. & Weinberg, R. A. Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein. Genes Dev. 8, 1759–1771 (1994). (10.1101/gad.8.15.1759) / Genes Dev. by M Hatekeyama (1994)
Resnitzky, D. & Reed, S. I. Different roles for cyclins D1 and E in regulation of the G1-to-S transition. Mol. Cell. Biol. 15, 3463–3469 (1995). (10.1128/MCB.15.7.3463) / Mol. Cell. Biol. by D Resnitzky (1995)
Galaktionov, K., Chen, X. & Beach, D. Cdc25 cell-cycle phosphatase as a target of c-myc. Nature 382, 511–517 (1996). (10.1038/382511a0) / Nature by K Galaktionov (1996)
Duronio, R. J., O'Farrell, P. H., Xie, J.-E., Brook, A. & Dyson, N. The transcription factor E2F is required for S phase during Drosophila embryogenesis. Genes Dev. 9, 1445–1455 (1995). (10.1101/gad.9.12.1445) / Genes Dev. by RJ Duronio (1995)
Duronio, R. J., Brook, A., Dyson, N. & O'Farrell, P. H. E2F-induced S phase requires cyclin E. Genes Dev. 10, 2505–2513 (1996). (10.1101/gad.10.19.2505) / Genes Dev. by RJ Duronio (1996)
Steiner, P. et al. Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes. EMBO J. 14, 4814–4826 (1995). (10.1002/j.1460-2075.1995.tb00163.x) / EMBO J. by P Steiner (1995)
Coats, S., Flanagan, W. M., Nourse, J. & Roberts, J. M. Requirement of p27Kipl for restriction point control of the fibroblast cell cycle. Science 272, 877–880 (1996). (10.1126/science.272.5263.877) / Science by S Coats (1996)
Nourse, J. et al. Interleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin. Nature 372, 570–573 (1994). (10.1038/372570a0) / Nature by J Nourse (1994)
Galaktionov, K., Jessus, C. & Beach, D. Rafl interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation. Genes Dev. 9, 1046–1058 (1995). (10.1101/gad.9.9.1046) / Genes Dev. by K Galaktionov (1995)
Nevins, J. R., DeGregori, J., Jakoi, L. & Leone, G. Functional analysis of E2F. Methods Enzymol. (in the press).
DeGregori, J., Kowalik, T. & Nevins, J. R. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis and G1/S regulatory cells. Mol. Cell. Biol. 15, 4215–4224 (1995). (10.1128/MCB.15.8.4215) / Mol. Cell. Biol. by J DeGregori (1995)
Schwarz, J. K. et al. Expression of the E2F1 transcription factor overcomes type β transforming growth factor-mediated growth suppression. Proc. Natl Acad. Sci. USA 92, 483–487 (1995). (10.1073/pnas.92.2.483) / Proc. Natl Acad. Sci. USA by JK Schwarz (1995)
Farnsworth, C. L. & Reig, L. A. Dominant inhibitory mutations in the Mg2+-binding site of RasH prevent its activation by GTP. Mol. Cell. Biol. 11, 4822–4829 (1991). (10.1128/MCB.11.10.4822) / Mol. Cell. Biol. by CL Farnsworth (1991)
Khosravi-Far, R., Solski, P. A., Clark, G. J., Kinch, M. S. & Der, C. J. Activation of Racl, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Mol. Cell. Biol. 15, 6443–6453 (1995). (10.1128/MCB.15.11.6443) / Mol. Cell. Biol. by R Khosravi-Far (1995)
Ikeda, M.-A., Jakoi, L. & Nevins, J. R. A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proc. Natl Acad. Sci. USA 93, 3215–3220 (1996). (10.1073/pnas.93.8.3215) / Proc. Natl Acad. Sci. USA by M-A Ikeda (1996)
Jacks, T. et al. Effects of an Rb mutation in the mousse. Nature 359, 295–300 (1992). (10.1038/359295a0) / Nature by T Jacks (1992)
Smith, E. J., Leone, G., DeGregori, J., Jakoi, L. & Nevins, J. R. The accumulation of an E2F-p130 transcriptional represser distinguishes a GO from a Gl cell state. Mol. Cell. Biol. 16, 6965–6976 (1996). (10.1128/MCB.16.12.6965) / Mol. Cell. Biol. by EJ Smith (1996)
DeGregori, J., Leone, G., Ohtani, K., Miron, A. & Nevins, J. R. E2F1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity. Genes Dev. 9, 2873–2887 (1995). (10.1101/gad.9.23.2873) / Genes Dev. by J DeGregori (1995)

Dates

Type	When
Created	22 years ago (Aug. 11, 2003, 10:29 p.m.)
Deposited	3 years ago (July 29, 2022, 3:35 p.m.)
Indexed	1 month, 2 weeks ago (July 6, 2025, 1:26 p.m.)
Issued	28 years, 3 months ago (May 22, 1997)
Published	28 years, 3 months ago (May 22, 1997)
Published Print	28 years, 3 months ago (May 22, 1997)

Funders 0

None

BibTeX

@article{Leone_1997, title={Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F}, volume={387}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/387422a0}, DOI={10.1038/387422a0}, number={6631}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Leone, Gustavo and DeGregori, James and Sears, Rosalie and Jakoi, Laszlo and Nevins, Joseph R.}, year={1997}, month=may, pages={422–426} }

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