DOI: 10.1038/386044a0. A Polycomb-group gene regulates homeotic gene expression in Arabidopsis

A Polycomb-group gene regulates homeotic gene expression in Arabidopsis

10.1038/386044a0

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Goodrich, J., Puangsomlee, P., Martin, M., Long, D., Meyerowitz, E. M., & Coupland, G. (1997). A Polycomb-group gene regulates homeotic gene expression in Arabidopsis. Nature, 386(6620), 44â51.

Authors 6

Justin Goodrich (first)
Preeya Puangsomlee (additional)
Marta Martin (additional)
Deborah Long (additional)
Elliot M. Meyerowitz (additional)
George Coupland (additional)

References 50 Referenced 628

Coen, E. S. & Meyerowitz, E. M. The war of the whorls: genetic interactions controlling flower development. Nature 353, 31–37 (1991). (10.1038/353031a0) / Nature by ES Coen (1991)
Lewis, E. B. A gene complex controlling segmentation in Drosophila. Nature 276, 565–570 (1978). (10.1038/276565a0) / Nature by EB Lewis (1978)
Bowman, J. L, Smyth, D. R. & Meyerowitz, E. M. Genes directing flower development in Arabidopsis. Plant Cell 1, 37–52 (1989). (10.1105/tpc.1.1.37) / Plant Cell by JL Bowman (1989)
Carpenter, R. & Coen, E. S. Floral homeotic mutations produced by transposon-mutagenesis in Antirrhinum jamus. Genes Dev. 4, 1483–1493 (1990). (10.1101/gad.4.9.1483) / Genes Dev. by R Carpenter (1990)
Struhl, G. Genes controlling segmentation specification in the Drosophila thorax. Proc. Natl Acad. Sci. USA 79, 7380–7384 (1982). (10.1073/pnas.79.23.7380) / Proc. Natl Acad. Sci. USA by G Struhl (1982)
Ingham, P. W. The molecular genetics of embryonic pattern formation in Drosophila. Nature 335, 25–33 (1988). (10.1038/335025a0) / Nature by PW Ingham (1988)
Weigel, D. & Meyerowitz, E. M. The ABCs of floral homeotic genes. Cell 78, 203–209 (1994). (10.1016/0092-8674(94)90291-7) / Cell by D Weigel (1994)
Heemskerk, J., DiNardo, S., Kostriken, R. & O'Farrell, P. H. Multiple modes of engrailed regulation in the progression towards cell fate determination. Nature 352, 404–410 (1991). (10.1038/352404a0) / Nature by J Heemskerk (1991)
Simcox, A. A. & Sang, J. H. When does determination occur in Drosophila embryos? Dev. Biol. 97, 212–221 (1983). (10.1016/0012-1606(83)90078-7) / Dev. Biol. by AA Simcox (1983)
Lawrence, P. A. & Morata, G. in Insect Development (ed. Lawrence, P. A.) 132–148 (Blackwell, Oxford, 1976). / Insect Development by PA Lawrence (1976)
Simon, J. Locking in stable states of gene expression: transcriptional control during Drosophila development. Curr. Opin. Cell Biol. 7, 376–385 (1995). (10.1016/0955-0674(95)80093-X) / Curr. Opin. Cell Biol. by J Simon (1995)
Kennison, J. A. Transcriptional activation of Drosophila homeotic genes from distant regulatory elements. Trends Genet. 9, 75–79 (1993). (10.1016/0168-9525(93)90227-9) / Trends Genet. by JA Kennison (1993)
Struhl, G. & Akam, M. Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila. EMBO J. 4, 3259–3264 (1985). (10.1002/j.1460-2075.1985.tb04075.x) / EMBO J. by G Struhl (1985)
Jones, R. S. & Gelbart, W. M. Genetic analysis of the Enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster. Genetics 126, 185–199 (1990). (10.1093/genetics/126.1.185) / Genetics by RS Jones (1990)
Breene, T. R. & Harte, P. J. trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development 117, 119–134 (1993). (10.1242/dev.117.1.119) / Development by TR Breene (1993)
Grindhart, J. G. J. & Kaufman, T. C. Identification of polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene sex combs reduced. Genetics 139, 797–814 (1995). (10.1093/genetics/139.2.797) / Genetics by JGJ Grindhart (1995)
Muller, J. Transcriptional silencing by the Polycomb protein in Drosophila embryos. EMBO J. 14, 1209–1220 (1995). (10.1002/j.1460-2075.1995.tb07104.x) / EMBO J. by J Muller (1995)
Paro, R. Imprinting a determined state into the chromatin of Drosophila. Trends Genet. 6, 416–421 (1990). (10.1016/0168-9525(90)90303-N) / Trends Genet. by R Paro (1990)
Weigel, D. & Doerner, P. Cell–cell interactions—taking cues for the neighbors. Curr. Biol. 6, 10–12 (1996). (10.1016/S0960-9822(02)00408-6) / Curr. Biol. by D Weigel (1996)
Irish, E. E. & Nelson, T. M. Identification of multiple stages in the conversion of maize meristems from vegetative to floral development. Development 112, 891–898 (1991). (10.1242/dev.112.3.891) / Development by EE Irish (1991)
Bradley, D., Vincent, C., Carpenter, R. & Coen, E. Pathways for inflorescence and floral induction in Antirrhinum. Development 122, 1535–1544 (1996). (10.1242/dev.122.5.1535) / Development by D Bradley (1996)
Yanofsky, M. F. et al. The protein encoded by the Arabidopsis homeotic gene AGAMOUS resembles transcription factors. Nature 346, 35–39 (1990). (10.1038/346035a0) / Nature by MF Yanofsky (1990)
Drews, G. N., Bowman, J. L. & Meyerowitz, E. M. Negative regulation of the Arabidopsis homeotic gene AGAMOUS by the APETALA2 product. Cell 65, 991–1002 (1991). (10.1016/0092-8674(91)90551-9) / Cell by GN Drews (1991)
Long, D. et al. The maize transposable element system Ac/Ds as a mutagen in Arabidopsis: Identification of an albino mutation induced by Ds insertion. Proc. Natl Acad. Sci. USA 90, 10370–10374 (1993). (10.1073/pnas.90.21.10370) / Proc. Natl Acad. Sci. USA by D Long (1993)
Mizukami, Y. & Ma, H. Ectopic expression of the floral homeotic gene AGAMOUS in transgenic Arabidopsis plants alters floral organ identity. Cell 71, 119–131 (1992). (10.1016/0092-8674(92)90271-D) / Cell by Y Mizukami (1992)
Jack, T., Fox, G. L. & Meyerowitz, E. M. Arabidopsis homeotic gene APETALA3 ectopic expression—transcriptional and posttranscriptional regulation determined floral organ identity. Cell 76, 703–716 (1994). (10.1016/0092-8674(94)90509-6) / Cell by T Jack (1994)
Liu, Z. & Meyerowitz, E. M. LEUNIG regulates AGAMOUS expression in Arabidopsis flowers. Development 121, 975–991 (1995). (10.1242/dev.121.4.975) / Development by Z Liu (1995)
Sutton, W. D., Gerlach, W. L., Schwartz, D. & Peacock, W. J. Molecular analysis of ds controlling element mutations at the ADH1 locus of maize. Science 223, 1265–1268 (1984). (10.1126/science.223.4642.1265) / Science by WD Sutton (1984)
Lüttke, H. A. et al. Selection of AUG initiation codons differs in plants and animals. EMBO J. 6, 43–48 (1987). (10.1002/j.1460-2075.1987.tb04716.x) / EMBO J. by HA Lüttke (1987)
Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman Basic local alignment search tool. J. Mol. Biol. 215 403–410 (1990). (10.1016/S0022-2836(05)80360-2) / J. Mol. Biol. by SF Altschul (1990)
Jones, R. S. & Gelbart, W. M. The Drosophila Polycomb-group gene Enhancer of zeste contains region with a sequence similarity to trithorax. Mol. Cell. Biol. 13, 6357–6366 (1993). (10.1128/MCB.13.10.6357) / Mol. Cell. Biol. by RS Jones (1993)
Tschiersch, B. et al. The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var) 3–9 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J. 13, 3822–3831 (1994). (10.1002/j.1460-2075.1994.tb06693.x) / EMBO J. by B Tschiersch (1994)
Carrington, E. A. & Jones, R. S. The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution. Development 122, 4073–4083 (1996). (10.1242/dev.122.12.4073) / Development by EA Carrington (1996)
Paro, R. & Hogness, D. S. The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl Acad. Sci. USA 88, 263–267 (1991). (10.1073/pnas.88.1.263) / Proc. Natl Acad. Sci. USA by R Paro (1991)
Rastelli, L., Chan, C. S. & Pirotta, V. Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function. EMBO J. 12, 1513–1522 (1993). (10.1002/j.1460-2075.1993.tb05795.x) / EMBO J. by L Rastelli (1993)
Tsukiyama, T., Becker, P. B. & Wu, C. ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor. Nature 367, 525–532 (1994). (10.1038/367525a0) / Nature by T Tsukiyama (1994)
Côté, J., Quinn, J., Workman, J. L. & Peterson, C. L. Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science 265, 53–60 (1994). (10.1126/science.8016655) / Science by J Côté (1994)
Finnegan, E. J., Peacock, W. J. & Dennis, E. S. Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development. Proc. Natl Acad. Sci. USA 93, 8449–8454 (1996). (10.1073/pnas.93.16.8449) / Proc. Natl Acad. Sci. USA by EJ Finnegan (1996)
Ronemus, M. J., Galbiati, M., Ticknor, C., Chen, J. C. & Dellaporta, S. L. Demethylation-induced developmental pleiotropy in Arabidopsis. Science 273, 654–657 (1996). (10.1126/science.273.5275.654) / Science by MJ Ronemus (1996)
Jofuku, D., van den Boer, B., Van Montagu, M. & Okamuro, J. Control of Arabidopsis flower and seed development by the homeotic gene APETALA2. Plant Cell 6, 1211–1225 (1994). (10.1105/tpc.6.9.1211) / Plant Cell by D Jofuku (1994)
van der Lugt, N. M. T. et al. Posterior transformation, neurological abnormalities, and severe hematapoietic defects in mice with a targeted deletion of the bmi-1 protooncogene. Genes Dev. 8, 757–769 (1994). (10.1101/gad.8.7.757) / Genes Dev. by NMT van der Lugt (1994)
Akaseka, T. et al. A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton. Development 122, 1513–1522 (1996). (10.1242/dev.122.5.1513) / Development by T Akaseka (1996)
Krumlauf, R. Hox genes in vertebrate development. Cell 78, 191–201 (1994). (10.1016/0092-8674(94)90290-9) / Cell by R Krumlauf (1994)
van den Berg, C., Willemsen, V., Hage, W., Weisbeek, P. & Scheres, B. Determination of cell fate in the Arabidopsis root meristem by directional signalling. Nature 378, 62–65 (1995). (10.1038/378062a0) / Nature by C van den Berg (1995)
Tröbner, W. et al. Globosa—A homeotic gene which interacts with deficiens in the control of Antirrhinum floral organogenesis. EMBO J. 11, 4693–4704 (1992). (10.1002/j.1460-2075.1992.tb05574.x) / EMBO J. by W Tröbner (1992)
Putterill, J., Robson, F., Lee, K., Simon, R. & Coupland, G. The CONSTANS gene of Arabidopsis promotes flowering and encodes a protein showing similarities to zinc finger transcription factors. Cell 80, 847–857 (1995). (10.1016/0092-8674(95)90288-0) / Cell by J Putterill (1995)
Coen, E. S., Carpenter, R. & Martin, C. Transposable elements generate novel spatial patterns of gene expression in Antirrhinum majus. Cell 47, 285–296 (1986). (10.1016/0092-8674(86)90451-4) / Cell by ES Coen (1986)
Jack, T., Brockman, L. L. & Meyerowitz, E. M. The homeotic gene APETALA3 of Arabidopsis thaliana encodes a MADS box and is expressed in petals and stamens. Cell 68, 683–697 (1992). (10.1016/0092-8674(92)90144-2) / Cell by T Jack (1992)
Weigel, D., Alvarez, J., Smyth, D. R., Yanofsky, M. F. & Meyerowitz, E. M. LEAFY controls floral meristem identity in Arabidopsis. Cell 69, 843–859 (1992). (10.1016/0092-8674(92)90295-N) / Cell by D Weigel (1992)
Coen, E. S. et al. Floricaula: a homeotic gene required for flower development in Antirrhinum majus. Cell 63, 1311–1322 (1990). (10.1016/0092-8674(90)90426-F) / Cell by ES Coen (1990)

Dates

Type	When
Created	22 years ago (Aug. 11, 2003, 10:24 p.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 11:05 p.m.)
Indexed	3 days, 11 hours ago (Aug. 29, 2025, 6:23 a.m.)
Issued	28 years, 6 months ago (March 1, 1997)
Published	28 years, 6 months ago (March 1, 1997)
Published Print	28 years, 6 months ago (March 1, 1997)

Funders 0

None

BibTeX

@article{Goodrich_1997, title={A Polycomb-group gene regulates homeotic gene expression in Arabidopsis}, volume={386}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/386044a0}, DOI={10.1038/386044a0}, number={6620}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Goodrich, Justin and Puangsomlee, Preeya and Martin, Marta and Long, Deborah and Meyerowitz, Elliot M. and Coupland, George}, year={1997}, month=mar, pages={44–51} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        29
      ]
    ],
    "date-time": "2025-08-29T10:23:01Z",
    "timestamp": 1756462981450
  },
  "reference-count": 50,
  "publisher": "Springer Science and Business Media LLC",
  "issue": "6620",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1997,
            3,
            1
          ]
        ],
        "date-time": "1997-03-01T00:00:00Z",
        "timestamp": 857174400000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "http://www.springer.com/tdm"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1997,
        3
      ]
    ]
  },
  "DOI": "10.1038/386044a0",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2003,
        8,
        12
      ]
    ],
    "date-time": "2003-08-12T02:24:14Z",
    "timestamp": 1060655054000
  },
  "page": "44-51",
  "source": "Crossref",
  "is-referenced-by-count": 628,
  "title": "A Polycomb-group gene regulates homeotic gene expression in Arabidopsis",
  "prefix": "10.1038",
  "volume": "386",
  "author": [
    {
      "given": "Justin",
      "family": "Goodrich",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "Preeya",
      "family": "Puangsomlee",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Marta",
      "family": "Martin",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Deborah",
      "family": "Long",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "Elliot M.",
      "family": "Meyerowitz",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "George",
      "family": "Coupland",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "297",
  "reference": [
    {
      "key": "BF386044a0_CR1",
      "doi-asserted-by": "publisher",
      "first-page": "31",
      "DOI": "10.1038/353031a0",
      "volume": "353",
      "author": "ES Coen",
      "year": "1991",
      "unstructured": "Coen, E. S. & Meyerowitz, E. M. The war of the whorls: genetic interactions controlling flower development. Nature 353, 31\u201337 (1991).",
      "journal-title": "Nature"
    },
    {
      "key": "BF386044a0_CR2",
      "doi-asserted-by": "publisher",
      "first-page": "565",
      "DOI": "10.1038/276565a0",
      "volume": "276",
      "author": "EB Lewis",
      "year": "1978",
      "unstructured": "Lewis, E. B. A gene complex controlling segmentation in Drosophila. Nature 276, 565\u2013570 (1978).",
      "journal-title": "Nature"
    },
    {
      "key": "BF386044a0_CR3",
      "doi-asserted-by": "publisher",
      "first-page": "37",
      "DOI": "10.1105/tpc.1.1.37",
      "volume": "1",
      "author": "JL Bowman",
      "year": "1989",
      "unstructured": "Bowman, J. L, Smyth, D. R. & Meyerowitz, E. M. Genes directing flower development in Arabidopsis. Plant Cell 1, 37\u201352 (1989).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "BF386044a0_CR4",
      "doi-asserted-by": "publisher",
      "first-page": "1483",
      "DOI": "10.1101/gad.4.9.1483",
      "volume": "4",
      "author": "R Carpenter",
      "year": "1990",
      "unstructured": "Carpenter, R. & Coen, E. S. Floral homeotic mutations produced by transposon-mutagenesis in Antirrhinum jamus. Genes Dev. 4, 1483\u20131493 (1990).",
      "journal-title": "Genes Dev."
    },
    {
      "key": "BF386044a0_CR5",
      "doi-asserted-by": "publisher",
      "first-page": "7380",
      "DOI": "10.1073/pnas.79.23.7380",
      "volume": "79",
      "author": "G Struhl",
      "year": "1982",
      "unstructured": "Struhl, G. Genes controlling segmentation specification in the Drosophila thorax. Proc. Natl Acad. Sci. USA 79, 7380\u20137384 (1982).",
      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
    {
      "key": "BF386044a0_CR6",
      "doi-asserted-by": "publisher",
      "first-page": "25",
      "DOI": "10.1038/335025a0",
      "volume": "335",
      "author": "PW Ingham",
      "year": "1988",
      "unstructured": "Ingham, P. W. The molecular genetics of embryonic pattern formation in Drosophila. Nature 335, 25\u201333 (1988).",
      "journal-title": "Nature"
    },
    {
      "key": "BF386044a0_CR7",
      "doi-asserted-by": "publisher",
      "first-page": "203",
      "DOI": "10.1016/0092-8674(94)90291-7",
      "volume": "78",
      "author": "D Weigel",
      "year": "1994",
      "unstructured": "Weigel, D. & Meyerowitz, E. M. The ABCs of floral homeotic genes. Cell 78, 203\u2013209 (1994).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR8",
      "doi-asserted-by": "publisher",
      "first-page": "404",
      "DOI": "10.1038/352404a0",
      "volume": "352",
      "author": "J Heemskerk",
      "year": "1991",
      "unstructured": "Heemskerk, J., DiNardo, S., Kostriken, R. & O'Farrell, P. H. Multiple modes of engrailed regulation in the progression towards cell fate determination. Nature 352, 404\u2013410 (1991).",
      "journal-title": "Nature"
    },
    {
      "key": "BF386044a0_CR9",
      "doi-asserted-by": "publisher",
      "first-page": "212",
      "DOI": "10.1016/0012-1606(83)90078-7",
      "volume": "97",
      "author": "AA Simcox",
      "year": "1983",
      "unstructured": "Simcox, A. A. & Sang, J. H. When does determination occur in Drosophila embryos? Dev. Biol. 97, 212\u2013221 (1983).",
      "journal-title": "Dev. Biol."
    },
    {
      "key": "BF386044a0_CR10",
      "first-page": "132",
      "volume-title": "Insect Development",
      "author": "PA Lawrence",
      "year": "1976",
      "unstructured": "Lawrence, P. A. & Morata, G. in Insect Development (ed. Lawrence, P. A.) 132\u2013148 (Blackwell, Oxford, 1976)."
    },
    {
      "key": "BF386044a0_CR11",
      "doi-asserted-by": "publisher",
      "first-page": "376",
      "DOI": "10.1016/0955-0674(95)80093-X",
      "volume": "7",
      "author": "J Simon",
      "year": "1995",
      "unstructured": "Simon, J. Locking in stable states of gene expression: transcriptional control during Drosophila development. Curr. Opin. Cell Biol. 7, 376\u2013385 (1995).",
      "journal-title": "Curr. Opin. Cell Biol."
    },
    {
      "key": "BF386044a0_CR12",
      "doi-asserted-by": "publisher",
      "first-page": "75",
      "DOI": "10.1016/0168-9525(93)90227-9",
      "volume": "9",
      "author": "JA Kennison",
      "year": "1993",
      "unstructured": "Kennison, J. A. Transcriptional activation of Drosophila homeotic genes from distant regulatory elements. Trends Genet. 9, 75\u201379 (1993).",
      "journal-title": "Trends Genet."
    },
    {
      "key": "BF386044a0_CR13",
      "doi-asserted-by": "publisher",
      "first-page": "3259",
      "DOI": "10.1002/j.1460-2075.1985.tb04075.x",
      "volume": "4",
      "author": "G Struhl",
      "year": "1985",
      "unstructured": "Struhl, G. & Akam, M. Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila. EMBO J. 4, 3259\u20133264 (1985).",
      "journal-title": "EMBO J."
    },
    {
      "key": "BF386044a0_CR14",
      "doi-asserted-by": "crossref",
      "first-page": "185",
      "DOI": "10.1093/genetics/126.1.185",
      "volume": "126",
      "author": "RS Jones",
      "year": "1990",
      "unstructured": "Jones, R. S. & Gelbart, W. M. Genetic analysis of the Enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster. Genetics 126, 185\u2013199 (1990).",
      "journal-title": "Genetics"
    },
    {
      "key": "BF386044a0_CR15",
      "doi-asserted-by": "crossref",
      "first-page": "119",
      "DOI": "10.1242/dev.117.1.119",
      "volume": "117",
      "author": "TR Breene",
      "year": "1993",
      "unstructured": "Breene, T. R. & Harte, P. J. trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development 117, 119\u2013134 (1993).",
      "journal-title": "Development"
    },
    {
      "key": "BF386044a0_CR16",
      "doi-asserted-by": "crossref",
      "first-page": "797",
      "DOI": "10.1093/genetics/139.2.797",
      "volume": "139",
      "author": "JGJ Grindhart",
      "year": "1995",
      "unstructured": "Grindhart, J. G. J. & Kaufman, T. C. Identification of polycomb and trithorax group responsive elements in the regulatory region of the Drosophila homeotic gene sex combs reduced. Genetics 139, 797\u2013814 (1995).",
      "journal-title": "Genetics"
    },
    {
      "key": "BF386044a0_CR17",
      "doi-asserted-by": "publisher",
      "first-page": "1209",
      "DOI": "10.1002/j.1460-2075.1995.tb07104.x",
      "volume": "14",
      "author": "J Muller",
      "year": "1995",
      "unstructured": "Muller, J. Transcriptional silencing by the Polycomb protein in Drosophila embryos. EMBO J. 14, 1209\u20131220 (1995).",
      "journal-title": "EMBO J."
    },
    {
      "key": "BF386044a0_CR18",
      "doi-asserted-by": "publisher",
      "first-page": "416",
      "DOI": "10.1016/0168-9525(90)90303-N",
      "volume": "6",
      "author": "R Paro",
      "year": "1990",
      "unstructured": "Paro, R. Imprinting a determined state into the chromatin of Drosophila. Trends Genet. 6, 416\u2013421 (1990).",
      "journal-title": "Trends Genet."
    },
    {
      "key": "BF386044a0_CR19",
      "doi-asserted-by": "publisher",
      "first-page": "10",
      "DOI": "10.1016/S0960-9822(02)00408-6",
      "volume": "6",
      "author": "D Weigel",
      "year": "1996",
      "unstructured": "Weigel, D. & Doerner, P. Cell\u2013cell interactions\u2014taking cues for the neighbors. Curr. Biol. 6, 10\u201312 (1996).",
      "journal-title": "Curr. Biol."
    },
    {
      "key": "BF386044a0_CR20",
      "doi-asserted-by": "crossref",
      "first-page": "891",
      "DOI": "10.1242/dev.112.3.891",
      "volume": "112",
      "author": "EE Irish",
      "year": "1991",
      "unstructured": "Irish, E. E. & Nelson, T. M. Identification of multiple stages in the conversion of maize meristems from vegetative to floral development. Development 112, 891\u2013898 (1991).",
      "journal-title": "Development"
    },
    {
      "key": "BF386044a0_CR21",
      "doi-asserted-by": "crossref",
      "first-page": "1535",
      "DOI": "10.1242/dev.122.5.1535",
      "volume": "122",
      "author": "D Bradley",
      "year": "1996",
      "unstructured": "Bradley, D., Vincent, C., Carpenter, R. & Coen, E. Pathways for inflorescence and floral induction in Antirrhinum. Development 122, 1535\u20131544 (1996).",
      "journal-title": "Development"
    },
    {
      "key": "BF386044a0_CR22",
      "doi-asserted-by": "publisher",
      "first-page": "35",
      "DOI": "10.1038/346035a0",
      "volume": "346",
      "author": "MF Yanofsky",
      "year": "1990",
      "unstructured": "Yanofsky, M. F. et al. The protein encoded by the Arabidopsis homeotic gene AGAMOUS resembles transcription factors. Nature 346, 35\u201339 (1990).",
      "journal-title": "Nature"
    },
    {
      "key": "BF386044a0_CR23",
      "doi-asserted-by": "publisher",
      "first-page": "991",
      "DOI": "10.1016/0092-8674(91)90551-9",
      "volume": "65",
      "author": "GN Drews",
      "year": "1991",
      "unstructured": "Drews, G. N., Bowman, J. L. & Meyerowitz, E. M. Negative regulation of the Arabidopsis homeotic gene AGAMOUS by the APETALA2 product. Cell 65, 991\u20131002 (1991).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR24",
      "doi-asserted-by": "publisher",
      "first-page": "10370",
      "DOI": "10.1073/pnas.90.21.10370",
      "volume": "90",
      "author": "D Long",
      "year": "1993",
      "unstructured": "Long, D. et al. The maize transposable element system Ac/Ds as a mutagen in Arabidopsis: Identification of an albino mutation induced by Ds insertion. Proc. Natl Acad. Sci. USA 90, 10370\u201310374 (1993).",
      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
    {
      "key": "BF386044a0_CR25",
      "doi-asserted-by": "publisher",
      "first-page": "119",
      "DOI": "10.1016/0092-8674(92)90271-D",
      "volume": "71",
      "author": "Y Mizukami",
      "year": "1992",
      "unstructured": "Mizukami, Y. & Ma, H. Ectopic expression of the floral homeotic gene AGAMOUS in transgenic Arabidopsis plants alters floral organ identity. Cell 71, 119\u2013131 (1992).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR26",
      "doi-asserted-by": "publisher",
      "first-page": "703",
      "DOI": "10.1016/0092-8674(94)90509-6",
      "volume": "76",
      "author": "T Jack",
      "year": "1994",
      "unstructured": "Jack, T., Fox, G. L. & Meyerowitz, E. M. Arabidopsis homeotic gene APETALA3 ectopic expression\u2014transcriptional and posttranscriptional regulation determined floral organ identity. Cell 76, 703\u2013716 (1994).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR27",
      "doi-asserted-by": "crossref",
      "first-page": "975",
      "DOI": "10.1242/dev.121.4.975",
      "volume": "121",
      "author": "Z Liu",
      "year": "1995",
      "unstructured": "Liu, Z. & Meyerowitz, E. M. LEUNIG regulates AGAMOUS expression in Arabidopsis flowers. Development 121, 975\u2013991 (1995).",
      "journal-title": "Development"
    },
    {
      "key": "BF386044a0_CR28",
      "doi-asserted-by": "publisher",
      "first-page": "1265",
      "DOI": "10.1126/science.223.4642.1265",
      "volume": "223",
      "author": "WD Sutton",
      "year": "1984",
      "unstructured": "Sutton, W. D., Gerlach, W. L., Schwartz, D. & Peacock, W. J. Molecular analysis of ds controlling element mutations at the ADH1 locus of maize. Science 223, 1265\u20131268 (1984).",
      "journal-title": "Science"
    },
    {
      "key": "BF386044a0_CR29",
      "doi-asserted-by": "publisher",
      "first-page": "43",
      "DOI": "10.1002/j.1460-2075.1987.tb04716.x",
      "volume": "6",
      "author": "HA L\u00fcttke",
      "year": "1987",
      "unstructured": "L\u00fcttke, H. A. et al. Selection of AUG initiation codons differs in plants and animals. EMBO J. 6, 43\u201348 (1987).",
      "journal-title": "EMBO J."
    },
    {
      "key": "BF386044a0_CR30",
      "doi-asserted-by": "publisher",
      "first-page": "403",
      "DOI": "10.1016/S0022-2836(05)80360-2",
      "volume": "215",
      "author": "SF Altschul",
      "year": "1990",
      "unstructured": "Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman Basic local alignment search tool. J. Mol. Biol. 215 403\u2013410 (1990).",
      "journal-title": "J. Mol. Biol."
    },
    {
      "key": "BF386044a0_CR31",
      "doi-asserted-by": "publisher",
      "first-page": "6357",
      "DOI": "10.1128/MCB.13.10.6357",
      "volume": "13",
      "author": "RS Jones",
      "year": "1993",
      "unstructured": "Jones, R. S. & Gelbart, W. M. The Drosophila Polycomb-group gene Enhancer of zeste contains region with a sequence similarity to trithorax. Mol. Cell. Biol. 13, 6357\u20136366 (1993).",
      "journal-title": "Mol. Cell. Biol."
    },
    {
      "key": "BF386044a0_CR32",
      "doi-asserted-by": "publisher",
      "first-page": "3822",
      "DOI": "10.1002/j.1460-2075.1994.tb06693.x",
      "volume": "13",
      "author": "B Tschiersch",
      "year": "1994",
      "unstructured": "Tschiersch, B. et al. The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var) 3\u20139 combines domains of antagonistic regulators of homeotic gene complexes. EMBO J. 13, 3822\u20133831 (1994).",
      "journal-title": "EMBO J."
    },
    {
      "key": "BF386044a0_CR33",
      "doi-asserted-by": "crossref",
      "first-page": "4073",
      "DOI": "10.1242/dev.122.12.4073",
      "volume": "122",
      "author": "EA Carrington",
      "year": "1996",
      "unstructured": "Carrington, E. A. & Jones, R. S. The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution. Development 122, 4073\u20134083 (1996).",
      "journal-title": "Development"
    },
    {
      "key": "BF386044a0_CR34",
      "doi-asserted-by": "publisher",
      "first-page": "263",
      "DOI": "10.1073/pnas.88.1.263",
      "volume": "88",
      "author": "R Paro",
      "year": "1991",
      "unstructured": "Paro, R. & Hogness, D. S. The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila. Proc. Natl Acad. Sci. USA 88, 263\u2013267 (1991).",
      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
    {
      "key": "BF386044a0_CR35",
      "doi-asserted-by": "publisher",
      "first-page": "1513",
      "DOI": "10.1002/j.1460-2075.1993.tb05795.x",
      "volume": "12",
      "author": "L Rastelli",
      "year": "1993",
      "unstructured": "Rastelli, L., Chan, C. S. & Pirotta, V. Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function. EMBO J. 12, 1513\u20131522 (1993).",
      "journal-title": "EMBO J."
    },
    {
      "key": "BF386044a0_CR36",
      "doi-asserted-by": "publisher",
      "first-page": "525",
      "DOI": "10.1038/367525a0",
      "volume": "367",
      "author": "T Tsukiyama",
      "year": "1994",
      "unstructured": "Tsukiyama, T., Becker, P. B. & Wu, C. ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor. Nature 367, 525\u2013532 (1994).",
      "journal-title": "Nature"
    },
    {
      "key": "BF386044a0_CR37",
      "doi-asserted-by": "publisher",
      "first-page": "53",
      "DOI": "10.1126/science.8016655",
      "volume": "265",
      "author": "J C\u00f4t\u00e9",
      "year": "1994",
      "unstructured": "C\u00f4t\u00e9, J., Quinn, J., Workman, J. L. & Peterson, C. L. Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex. Science 265, 53\u201360 (1994).",
      "journal-title": "Science"
    },
    {
      "key": "BF386044a0_CR38",
      "doi-asserted-by": "publisher",
      "first-page": "8449",
      "DOI": "10.1073/pnas.93.16.8449",
      "volume": "93",
      "author": "EJ Finnegan",
      "year": "1996",
      "unstructured": "Finnegan, E. J., Peacock, W. J. & Dennis, E. S. Reduced DNA methylation in Arabidopsis thaliana results in abnormal plant development. Proc. Natl Acad. Sci. USA 93, 8449\u20138454 (1996).",
      "journal-title": "Proc. Natl Acad. Sci. USA"
    },
    {
      "key": "BF386044a0_CR39",
      "doi-asserted-by": "publisher",
      "first-page": "654",
      "DOI": "10.1126/science.273.5275.654",
      "volume": "273",
      "author": "MJ Ronemus",
      "year": "1996",
      "unstructured": "Ronemus, M. J., Galbiati, M., Ticknor, C., Chen, J. C. & Dellaporta, S. L. Demethylation-induced developmental pleiotropy in Arabidopsis. Science 273, 654\u2013657 (1996).",
      "journal-title": "Science"
    },
    {
      "key": "BF386044a0_CR40",
      "doi-asserted-by": "publisher",
      "first-page": "1211",
      "DOI": "10.1105/tpc.6.9.1211",
      "volume": "6",
      "author": "D Jofuku",
      "year": "1994",
      "unstructured": "Jofuku, D., van den Boer, B., Van Montagu, M. & Okamuro, J. Control of Arabidopsis flower and seed development by the homeotic gene APETALA2. Plant Cell 6, 1211\u20131225 (1994).",
      "journal-title": "Plant Cell"
    },
    {
      "key": "BF386044a0_CR41",
      "doi-asserted-by": "publisher",
      "first-page": "757",
      "DOI": "10.1101/gad.8.7.757",
      "volume": "8",
      "author": "NMT van der Lugt",
      "year": "1994",
      "unstructured": "van der Lugt, N. M. T. et al. Posterior transformation, neurological abnormalities, and severe hematapoietic defects in mice with a targeted deletion of the bmi-1 protooncogene. Genes Dev. 8, 757\u2013769 (1994).",
      "journal-title": "Genes Dev."
    },
    {
      "key": "BF386044a0_CR42",
      "doi-asserted-by": "crossref",
      "first-page": "1513",
      "DOI": "10.1242/dev.122.5.1513",
      "volume": "122",
      "author": "T Akaseka",
      "year": "1996",
      "unstructured": "Akaseka, T. et al. A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton. Development 122, 1513\u20131522 (1996).",
      "journal-title": "Development"
    },
    {
      "key": "BF386044a0_CR43",
      "doi-asserted-by": "publisher",
      "first-page": "191",
      "DOI": "10.1016/0092-8674(94)90290-9",
      "volume": "78",
      "author": "R Krumlauf",
      "year": "1994",
      "unstructured": "Krumlauf, R. Hox genes in vertebrate development. Cell 78, 191\u2013201 (1994).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR44",
      "doi-asserted-by": "publisher",
      "first-page": "62",
      "DOI": "10.1038/378062a0",
      "volume": "378",
      "author": "C van den Berg",
      "year": "1995",
      "unstructured": "van den Berg, C., Willemsen, V., Hage, W., Weisbeek, P. & Scheres, B. Determination of cell fate in the Arabidopsis root meristem by directional signalling. Nature 378, 62\u201365 (1995).",
      "journal-title": "Nature"
    },
    {
      "key": "BF386044a0_CR45",
      "doi-asserted-by": "publisher",
      "first-page": "4693",
      "DOI": "10.1002/j.1460-2075.1992.tb05574.x",
      "volume": "11",
      "author": "W Tr\u00f6bner",
      "year": "1992",
      "unstructured": "Tr\u00f6bner, W. et al. Globosa\u2014A homeotic gene which interacts with deficiens in the control of Antirrhinum floral organogenesis. EMBO J. 11, 4693\u20134704 (1992).",
      "journal-title": "EMBO J."
    },
    {
      "key": "BF386044a0_CR46",
      "doi-asserted-by": "publisher",
      "first-page": "847",
      "DOI": "10.1016/0092-8674(95)90288-0",
      "volume": "80",
      "author": "J Putterill",
      "year": "1995",
      "unstructured": "Putterill, J., Robson, F., Lee, K., Simon, R. & Coupland, G. The CONSTANS gene of Arabidopsis promotes flowering and encodes a protein showing similarities to zinc finger transcription factors. Cell 80, 847\u2013857 (1995).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR47",
      "doi-asserted-by": "publisher",
      "first-page": "285",
      "DOI": "10.1016/0092-8674(86)90451-4",
      "volume": "47",
      "author": "ES Coen",
      "year": "1986",
      "unstructured": "Coen, E. S., Carpenter, R. & Martin, C. Transposable elements generate novel spatial patterns of gene expression in Antirrhinum majus. Cell 47, 285\u2013296 (1986).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR48",
      "doi-asserted-by": "publisher",
      "first-page": "683",
      "DOI": "10.1016/0092-8674(92)90144-2",
      "volume": "68",
      "author": "T Jack",
      "year": "1992",
      "unstructured": "Jack, T., Brockman, L. L. & Meyerowitz, E. M. The homeotic gene APETALA3 of Arabidopsis thaliana encodes a MADS box and is expressed in petals and stamens. Cell 68, 683\u2013697 (1992).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR49",
      "doi-asserted-by": "publisher",
      "first-page": "843",
      "DOI": "10.1016/0092-8674(92)90295-N",
      "volume": "69",
      "author": "D Weigel",
      "year": "1992",
      "unstructured": "Weigel, D., Alvarez, J., Smyth, D. R., Yanofsky, M. F. & Meyerowitz, E. M. LEAFY controls floral meristem identity in Arabidopsis. Cell 69, 843\u2013859 (1992).",
      "journal-title": "Cell"
    },
    {
      "key": "BF386044a0_CR50",
      "doi-asserted-by": "publisher",
      "first-page": "1311",
      "DOI": "10.1016/0092-8674(90)90426-F",
      "volume": "63",
      "author": "ES Coen",
      "year": "1990",
      "unstructured": "Coen, E. S. et al. Floricaula: a homeotic gene required for flower development in Antirrhinum majus. Cell 63, 1311\u20131322 (1990).",
      "journal-title": "Cell"
    }
  ],
  "container-title": "Nature",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "http://www.nature.com/articles/386044a0",
      "content-type": "text/html",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://www.nature.com/articles/386044a0.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://www.nature.com/articles/386044a0.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        5,
        17
      ]
    ],
    "date-time": "2023-05-17T03:05:11Z",
    "timestamp": 1684292711000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://www.nature.com/articles/386044a0"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1997,
        3
      ]
    ]
  },
  "references-count": 50,
  "journal-issue": {
    "issue": "6620",
    "published-print": {
      "date-parts": [
        [
          1997,
          3
        ]
      ]
    }
  },
  "alternative-id": [
    "BF386044a0"
  ],
  "URL": "http://dx.doi.org/10.1038/386044a0",
  "relation": {},
  "ISSN": [
    "0028-0836",
    "1476-4687"
  ],
  "subject": [],
  "container-title-short": "Nature",
  "published": {
    "date-parts": [
      [
        1997,
        3
      ]
    ]
  }
}