A model for p53-induced apoptosis
10.1038/38525
Crossref journal-article
Springer Science and Business Media LLC
Nature (297)
Bibliography

Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K. W., & Vogelstein, B. (1997). A model for p53-induced apoptosis. Nature, 389(6648), 300–305.

Authors 5
  1. Kornelia Polyak (first)
  2. Yong Xia (additional)
  3. Jay L. Zweier (additional)
  4. Kenneth W. Kinzler (additional)
  5. Bert Vogelstein (additional)
References 29 Referenced 1,998
  1. Waldman, T., Kinzler, K. W. & Vogelstein, B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55, 5187–5190 (1995). / Cancer Res. by T Waldman (1995)
  2. Oren, M. Relationship of p53 to the control of apoptotic cell death. Semin. Cancer Biol. 5, 221–227 (1994). / Semin. Cancer Biol. by M Oren (1994)
  3. Velculescu, V. E., Zhang, L., Vogelstein, B. & Kinzler, K. W. Serial analysis of gene expression. Science 270, 484–487 (1995). (10.1126/science.270.5235.484) / Science by VE Velculescu (1995)
  4. Polyak, K., Walkman, T., He, T.-C., Kinzler, K. W. & Vogelstein, B. Genetic determinants of p53 induced apoptosis and growth arrest. Genes Dev. 10, 1945–1952 (1966). (10.1101/gad.10.15.1945) / Genes Dev. by K Polyak (1966)
  5. Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell 88, 323–331 (1997). (10.1016/S0092-8674(00)81871-1) / Cell by AJ Levine (1997)
  6. Lehar, S. M.et al. Identification and cloning of Ei24, a gene induced by p53 in etoposide-treated cells. Oncogene 12, 1181–1187 (1996). / Oncogene by SM Lehar (1996)
  7. Hayward, D. C.et al. The sluggish-A gene of Drosophila melanogaster is expressed in the nervous system and encodes proline oxidase, a mitochondrial enzyme involved in glutamate biosynthesis. Proc. Natl Acad. Sci. USA 90, 2979–2983 (1993). (10.1073/pnas.90.7.2979) / Proc. Natl Acad. Sci. USA by DC Hayward (1993)
  8. Russo, T.et al. Ap53-independent pathway for activation of WAF1/CIP1 expression following oxidative stress. J. Biol. Chem. 270, 29386–29391 (1995). (10.1074/jbc.270.49.29386) / J. Biol. Chem. by T Russo (1995)
  9. Reinhoff, H. Y. J, Huang, J. H., Li, X. X. & Liao, W. S. Molecular and cellular biology of serum amyloid A. Mol. Biol. Med. 7, 287–298 (1990). / Mol. Biol. Med. by HYJ Reinhoff (1990)
  10. Yamaoka, A., Kuwabara, I., Frigeri, I. G. & Liu, F. T. Ahuman lectin, galectin-3 (epsilon bp/Mac-2) stimulates superoxide production by neutrophils. J. Immunol. 154, 3479–3487 (1995). (10.4049/jimmunol.154.7.3479) / J. Immunol. by A Yamaoka (1995)
  11. Greenberg, J. T. Programmed cell death: A way of life for plants. Proc. Natl Acad. Sci. USA 93, 12094–12097 (1996). (10.1073/pnas.93.22.12094) / Proc. Natl Acad. Sci. USA by JT Greenberg (1996)
  12. Rao, P. V., Krishna, C. M. & Zigler, J. S. J Identification and characterization of the enzymatic activity of zeta-crystallin from guinea PIG lens. A novel NADPH : quinone oxidoreductase. J. Biol. Chem. 267, 96–102 (1992). (10.1016/S0021-9258(18)48464-5) / J. Biol. Chem. by PV Rao (1992)
  13. Kroemer, G., Zamzami, N. & Susin, S. A. Mitochondrial control of apoptosis. Immun. Today 18, 45–51 (1997). (10.1016/S0167-5699(97)80014-X) / Immun. Today by G Kroemer (1997)
  14. Zamzami, N.et al. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181, 1661–1672 (1995). (10.1084/jem.181.5.1661) / J. Exp. Med. by N Zamzami (1995)
  15. Petit, P. X.et al. Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J. Cell. Biol. 130, 157–167 (1995). (10.1083/jcb.130.1.157) / J. Cell. Biol. by PX Petit (1995)
  16. Tamm, I. & Sehgal, P. B. Halobenzimidazole ribosides and RNA synthesis of cells and viruses. Adv. Virus Res. 22, 187–258 (1978). (10.1016/S0065-3527(08)60775-7) / Adv. Virus Res. by I Tamm (1978)
  17. Orrenius, S., Nobel, C. S. I., van den Dobbelsteen, D. J., Burkitt, M. J. & Slater, A. F. G. Dithiocarbamates and the redox regulation of cell death. Biochem. Soc. Transact. 24, 1032–1038 (1996). (10.1042/bst0241032) / Biochem. Soc. Transact. by S Orrenius (1996)
  18. Holland, P. C., Clark, M. G., Bloxham, D. P. & Lardy, H. A. Mechanism of action of the hypoglycemic agent diphenyleneiodonium. J. Biol. Chem. 248, 6050–6056 (1973). (10.1016/S0021-9258(19)43506-0) / J. Biol. Chem. by PC Holland (1973)
  19. Korsmeyer, S. J. Regulators of cell death. Trends Genet. 11, 101–105 (1995). (10.1016/S0168-9525(00)89010-1) / Trends Genet. by SJ Korsmeyer (1995)
  20. Susin, S. A.et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184, 1331–1341 (1996). (10.1084/jem.184.4.1331) / J. Exp. Med. by SA Susin (1996)
  21. Yang, J.et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129–1132 (1997). (10.1126/science.275.5303.1129) / Science by J Yang (1997)
  22. Kluck, R. M., Bossy-Wetzel, E., Green, D. R. & Newmeyer, D. D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132–1136 (1997). (10.1126/science.275.5303.1132) / Science by RM Kluck (1997)
  23. Borek, C. Radiation and chemically induced transformation: free radicals, antioxidants and cancer. Br. J. Cancer suppl. 8, 74–86 (1987). / Br. J. Cancer suppl. by C Borek (1987)
  24. Vayssiere, J. L., Petit, P. X., Risler, Y. & Mignotte, B. Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc. Natl Acad. Sci. USA 91, 11752–11756 (1994). (10.1073/pnas.91.24.11752) / Proc. Natl Acad. Sci. USA by JL Vayssiere (1994)
  25. Johnson, T. M., Yu, Z.-X., Ferrans, V. J., Lowenstein, R. A. & Finkel, T. Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc. Natl Acad. Sci. USA 93, 11848–11852 (1996). (10.1073/pnas.93.21.11848) / Proc. Natl Acad. Sci. USA by TM Johnson (1996)
  26. El-Diery, W. S.et al. WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817–825 (1993). (10.1016/0092-8674(93)90500-P) / Cell by WS El-Diery (1993)
  27. Velculescu, V. E.et al. Characterization of the yeast transcriptome. Cell 88, 243–251 (1997). (10.1016/S0092-8674(00)81845-0) / Cell by VE Velculescu (1997)
  28. El-Deiry, W. S., Kern, S. E., Pietenpol, J. A., Kinzler, K. W. & Vogelstein, B. Definition of a consensus binding site for p53. Nature Genet. 1, 45–49 (1992). (10.1038/ng0492-45) / Nature Genet. by WS El-Deiry (1992)
  29. Faulkner, K. & Fridovich, I. Luminol and lucigenin as detectors for O−2. Free Rad. Biol. Med. 15, 447–451 (1993). (10.1016/0891-5849(93)90044-U) / Free Rad. Biol. Med. by K Faulkner (1993)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:37 a.m.)
Deposited 2 years, 3 months ago (May 16, 2023, 11 p.m.)
Indexed 3 weeks ago (Aug. 7, 2025, 4:42 p.m.)
Issued 27 years, 11 months ago (Sept. 1, 1997)
Published 27 years, 11 months ago (Sept. 1, 1997)
Published Print 27 years, 11 months ago (Sept. 1, 1997)
Funders 0

None

@article{Polyak_1997, title={A model for p53-induced apoptosis}, volume={389}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/38525}, DOI={10.1038/38525}, number={6648}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Polyak, Kornelia and Xia, Yong and Zweier, Jay L. and Kinzler, Kenneth W. and Vogelstein, Bert}, year={1997}, month=sep, pages={300–305} }