DOI: 10.1038/384134a0. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

10.1038/384134a0

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Garboczi, D. N., Ghosh, P., Utz, U., Fan, Q. R., Biddison, W. E., & Wiley, D. C. (1996). Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature, 384(6605), 134â141.

Authors 6

David N. Garboczi (first)
Partho Ghosh (additional)
Ursula Utz (additional)
Qing R. Fan (additional)
William E. Biddison (additional)
Don C. Wiley (additional)

References 53 Referenced 1,182

Hedrick, S. M. & Eidelman, F. J. in Fundamental Immunology (ed. Paul, W. E.) 383–420 (Raven, New York, 1993). / Fundamental Immunology by SM Hedrick (1993)
Madden, D. R. Annu. Rev. Immunol. 13, 587–622 (1995). (10.1146/annurev.iy.13.040195.003103) / Annu. Rev. Immunol. by DR Madden (1995)
Stern, L. J. & Wiley, D. C. Structure 2, 245–251 (1994). (10.1016/S0969-2126(00)00026-5) / Structure by LJ Stern (1994)
Bjorkman, P. J. et al. Nature 329, 506–512 (1987). (10.1038/329506a0) / Nature by PJ Bjorkman (1987)
Bjorkman, P. J. et al. Nature 329, 512–518 (1987). (10.1038/329512a0) / Nature by PJ Bjorkman (1987)
Shevach, E. M. & Rosenthal, A. S. J. Exp. Med. 138, 1213–1229 (1973). (10.1084/jem.138.5.1213) / J. Exp. Med. by EM Shevach (1973)
Katz, D. H., Hamaoka, T., Dorf, M. E. & Benacerraf, B. Proc. Natl Acad. Sci. USA 70, 2624–2628 (1973). (10.1073/pnas.70.9.2624) / Proc. Natl Acad. Sci. USA by DH Katz (1973)
Zinkernagel, R. M. & Doherty, P. C. Nature 248, 701–702 (1974). (10.1038/248701a0) / Nature by RM Zinkernagel (1974)
Davis, M. M. & Bjorkman, P. J. Nature 334, 395–402 (1988). (10.1038/334395a0) / Nature by MM Davis (1988)
Arden, B., Clark, S. P., Kabelitz, D. & Mak, T. Immunogenetics 42, 455–500 (1995). / Immunogenetics by B Arden (1995)
Rowen, L., Koop, B. F. & Hood, L. Science 272, 1755–1762 (1996). (10.1126/science.272.5269.1755) / Science by L Rowen (1996)
Bentley, H. A. & Mariuzza, R. A. Annu. Rev. Immunol. 14, 563–590 (1996). (10.1146/annurev.immunol.14.1.563) / Annu. Rev. Immunol. by HA Bentley (1996)
Chothia, C., Boswell, D. R. & Lesk, A. M. EMBO J. 7, 3745–3755 (1988). (10.1002/j.1460-2075.1988.tb03258.x) / EMBO J. by C Chothia (1988)
Claverie, J.-M., Prochnicka–Chalufour, A. & Bougueleret, L. Immunol. Today 10, 10–14 (1989). (10.1016/0167-5699(89)90058-3) / Immunol. Today by J-M Claverie (1989)
Jorgensen, J. L., Reay, P. A., Ehrich, E. W. & Davis, M. M. Annu. Rev. Immunol. 10, 835–873 (1992). (10.1146/annurev.iy.10.040192.004155) / Annu. Rev. Immunol. by JL Jorgensen (1992)
Jorgensen, J. L., Esser, U., Fazekas de St Groth, B., Reay, P. A. & Davis, M. M. Nature 355, 224–230 (1992). (10.1038/355224a0) / Nature by JL Jorgensen (1992)
Utz, U., Banks, D., Jacobson, S. & Biddison, W. E. J. Virol. 70, 843–851 (1996). (10.1128/JVI.70.2.843-851.1996) / J. Virol. by U Utz (1996)
Garboczi, D. N. et al. J. Immunol. (in the press).
Garboczi, D. N., Hung, D. T. & Wiley, D. C. Proc. Natl Acad. Sci. USA 89, 3429–3433 (1992). (10.1073/pnas.89.8.3429) / Proc. Natl Acad. Sci. USA by DN Garboczi (1992)
Madden, D. R., Garboczi, D. N. & Wiley, D. C. Cell 75, 693–708 (1993). (10.1016/0092-8674(93)90490-H) / Cell by DR Madden (1993)
Roman, G. C. & Osame, M. Lancet (I), 651 (1988). (10.1016/S0140-6736(88)91452-3) / Lancet by GC Roman (1988)
Elovaara, I. et al. J. Exp. Med. 177, 1567–1573 (1993). (10.1084/jem.177.6.1567) / J. Exp. Med. by I Elovaara (1993)
Sant'Angelo, D. B. et al. Immunity 4, 367–376 (1996). (10.1016/S1074-7613(00)80250-2) / Immunity by DB Sant'Angelo (1996)
Vasmatzis, G., Cornett, J., Sezerman, U. & DeLisi, C. J. Mol. Biol. 261, 72–89 (1996). (10.1006/jmbi.1996.0442) / J. Mol. Biol. by G Vasmatzis (1996)
Sun, R. et al. Immunity 3, 573–582 (1995). (10.1016/1074-7613(95)90128-0) / Immunity by R Sun (1995)
Wilson, I. A., Ghiara, J. B. & Stanfield, R. L. A Structural View of Immune Recognition by Antibodies 55th Forum in Immunology, 73–78 (1996).
Wilson, I. A. & Stanfield, R. L. Structure 3, 113–118 (1993). / Structure by IA Wilson (1993)
Bentley, G. A., Boulot, G., Karjalainen, K. & Mariuzza, R. A. Science 267, 1984–1987 (1995). (10.1126/science.7701320) / Science by GA Bentley (1995)
Fields, B. A. et al. Science 270, 1821–1824 (1995). (10.1126/science.270.5243.1821) / Science by BA Fields (1995)
Stanfield, R. L., Takimoto–Kamimura, M., Rini, J. M., Profy, A. T. & Wilson, I. A. Structure 1, 83–93 (1993). (10.1016/0969-2126(93)90024-B) / Structure by RL Stanfield (1993)
Garcia, K. C. et al. Science 274, 209–219 (1996). (10.1126/science.274.5285.209) / Science by KC Garcia (1996)
Padlan, E. A. Mol. Immunol. 31, 169–217 (1994). (10.1016/0161-5890(94)90001-9) / Mol. Immunol. by EA Padlan (1994)
Brown, J. H. et al. Nature 364, 33–39 (1993). (10.1038/364033a0) / Nature by JH Brown (1993)
Janeway, C. A. Jr et al. Cold Spring Harbor Symp. Quant. Biol. LIV, 657–666 (1989). (10.1101/SQB.1989.054.01.077) / Cold Spring Harbor Symp. Quant. Biol. by CA Janeway Jr (1989)
Matsui, K. et al. Science 254, 1788–1791 (1991). (10.1126/science.1763329) / Science by K Matsui (1991)
Wucherpfennig, K. W. & Strominger, J. L. Cell 80, 695–705 (1995). (10.1016/0092-8674(95)90348-8) / Cell by KW Wucherpfennig (1995)
Janeway, C. A. Jr Immunol. Today 13, 11–16 (1992). (10.1016/0167-5699(92)90198-G) / Immunol. Today by CA Janeway Jr (1992)
Matzinger, P. Annu. Rev. Immunol. 12, 991–1045 (1994). (10.1146/annurev.iy.12.040194.005015) / Annu. Rev. Immunol. by P Matzinger (1994)
Webster, D. M., Henry, A. H. & Reese, A. R. Curr. Opin. Struct. Biol. 4, 123–129 (1994). (10.1016/S0959-440X(94)90070-1) / Curr. Opin. Struct. Biol. by DM Webster (1994)
Stern, L. J. et al. Nature 368, 215–221 (1994). (10.1038/368215a0) / Nature by LJ Stern (1994)
Ignatowicz, L., Kappler, J. & Marrack, P. Cell 84, 521–529 (1996). (10.1016/S0092-8674(00)81028-4) / Cell by L Ignatowicz (1996)
Jerne, N. Eur. J. Immunol. 1, 1–9 (1971). (10.1002/eji.1830010102) / Eur. J. Immunol. by N Jerne (1971)
Miyazaki, T. et al. Cell 84, 531–541 (1996). (10.1016/S0092-8674(00)81029-6) / Cell by T Miyazaki (1996)
Collaborative Computational Project No. 4. Acta Crystallogr. D 50, 760–763 (1994). (10.1107/S0907444994003112)
Kleywegt, G. J. & Jones, T. A. From First Map to Final Model (CCP4), 59–66 (1994).
Jones, T. A., Zou, J.-Y., Cowan, S. W. & Kjeldgaard, M. Acta Crystallogr. A 47, 110–119 (1991). (10.1107/S0108767390010224) / Acta Crystallogr. A by TA Jones (1991)
Ghosh, P., Amaya, M., Mellins, E. & Wiley, D. C. Nature 378, 457–462 (1995). (10.1038/378457a0) / Nature by P Ghosh (1995)
Brünger, A. T. Nature 355, 472–475 (1992). (10.1038/355472a0) / Nature by AT Brünger (1992)
Madden, D. R., Gorga, J. C., Strominger, J. L. & Wiley, D. C. Cell 70, 1035–1048 (1992). (10.1016/0092-8674(92)90252-8) / Cell by DR Madden (1992)
Huang, C. C., Pettersen, E. F., Klein, T. E., Ferrin, T. E. & Langridge, R. J. Mol. Graph. 9, 230–236 (1991). (10.1016/0263-7855(91)80016-S) / J. Mol. Graph. by CC Huang (1991)
Kabat, E. A., Wu, T. T., Perry, H. M., Gottesman, K. S. & Foeller, C. Sequences of Proteins of Immunological Interest (US Department of Health and Human Services, PHS, NIH, Bethesda, 1991). / Sequences of Proteins of Immunological Interest by EA Kabat (1991)
Carson, M. J. Appl. Crystallogr. 24, 958–961 (1991). (10.1107/S0021889891007240) / J. Appl. Crystallogr. by M Carson (1991)
Brown, J. H. et al. Nature 332, 845–850 (1988). (10.1038/332845a0) / Nature by JH Brown (1988)

Dates

Type	When
Created	22 years ago (Aug. 11, 2003, 10:17 p.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 10:54 p.m.)
Indexed	5 days, 18 hours ago (Aug. 24, 2025, 6:59 p.m.)
Issued	28 years, 9 months ago (Nov. 1, 1996)
Published	28 years, 9 months ago (Nov. 1, 1996)
Published Print	28 years, 9 months ago (Nov. 1, 1996)

Funders 0

None

BibTeX

@article{Garboczi_1996, title={Structure of the complex between human T-cell receptor, viral peptide and HLA-A2}, volume={384}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/384134a0}, DOI={10.1038/384134a0}, number={6605}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Garboczi, David N. and Ghosh, Partho and Utz, Ursula and Fan, Qing R. and Biddison, William E. and Wiley, Don C.}, year={1996}, month=nov, pages={134–141} }

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      "volume": "70",
      "author": "DH Katz",
      "year": "1973",
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      "key": "BF384134a0_CR8",
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      "DOI": "10.1038/248701a0",
      "volume": "248",
      "author": "RM Zinkernagel",
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      "doi-asserted-by": "crossref",
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      "volume": "42",
      "author": "B Arden",
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    {
      "key": "BF384134a0_CR11",
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    },
    {
      "key": "BF384134a0_CR13",
      "doi-asserted-by": "crossref",
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      "author": "U Utz",
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