DOI: 10.1038/365781a0. The pathway to signal achievement

The pathway to signal achievement

10.1038/365781a0

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Egan, S. E., & Weinberg, R. A. (1993). The pathway to signal achievement. Nature, 365(6449), 781â783.

Authors 2

Sean E. Egan (first)
Robert A. Weinberg (additional)

References 42 Referenced 446

Bos, J. L. Cancer Res. 49, 4682–4689 (1989). / Cancer Res. by JL Bos (1989)
Bourne, H. R., Sanders, D. A. & McCormick, F. Nature 348, 125–132 (1990). (10.1038/348125a0) / Nature by HR Bourne (1990)
Lowy, D. R. & Willumsen, B. M. A. Rev. Biochem. 62, 851–891 (1993). (10.1146/annurev.bi.62.070193.004223) / A. Rev. Biochem. by DR Lowy (1993)
Trahey, M. & McCormick, F. Science 238, 542–545 (1987). (10.1126/science.2821624) / Science by M Trahey (1987)
Viskochil, D. et al. Cell 62, 187–192 (1990). (10.1016/0092-8674(90)90252-A) / Cell by D Viskochil (1990)
Cawthon, R. M. et al. Cell 62, 193–201 (1990). (10.1016/0092-8674(90)90253-B) / Cell by RM Cawthon (1990)
Wallace, M. R. et al. Science 249, 181–186 (1990). (10.1126/science.2134734) / Science by MR Wallace (1990)
DeClue, J. E. et al. Cell 69, 265–273 (1992). (10.1016/0092-8674(92)90407-4) / Cell by JE DeClue (1992)
Basu, T. et al. Nature 356, 713–715 (1992). (10.1038/356713a0) / Nature by T Basu (1992)
Bishop, J. M. Cell 64, 235–248 (1991). (10.1016/0092-8674(91)90636-D) / Cell by JM Bishop (1991)
Smith, M. R., DeGudicubus, S. J. & Stacey, D. W. Nature 320, 540–543 (1986). (10.1038/320540a0) / Nature by MR Smith (1986)
Broach, J. R. Trends Genet. 7, 28–33 (1991). (10.1016/0168-9525(91)90018-L) / Trends Genet. by JR Broach (1991)
Powers, S. Sem. Cancer Biol. 3, 209–218 (1992). / Sem. Cancer Biol. by S Powers (1992)
Jones, S., Vignais, M. L. & Broach, J. R. Molec. cell. Biol. 11, 2641–2646 (1991). (10.1128/MCB.11.5.2641) / Molec. cell. Biol. by S Jones (1991)
Egel, R., Nielsen, O. & Weilguny, D. Trends Genet. 6, 369–373 (1990). (10.1016/0168-9525(90)90279-F) / Trends Genet. by R Egel (1990)
Errede, B. & Levin, D. E. Curr. Opin. Cell Biol. 5, 254–260 (1993). (10.1016/0955-0674(93)90112-4) / Curr. Opin. Cell Biol. by B Errede (1993)
Greenwald, I. & Rubin, G. M. Cell 68, 271–281 (1992). (10.1016/0092-8674(92)90470-W) / Cell by I Greenwald (1992)
Perrimon, N. Cell 74, 219–222 (1993). (10.1016/0092-8674(93)90412-J) / Cell by N Perrimon (1993)
Horvitz, H. R. & Sternberg, P. W. Nature 351, 535–541 (1991). (10.1038/351535a0) / Nature by HR Horvitz (1991)
Moodie, S. A., Willumsen, B. M., Weber, M. J. & Wolfman, A. Science 260, 1658–1661 (1993). (10.1126/science.8503013) / Science by SA Moodie (1993)
Van Aelst, L., Barr, M., Marcus, S., Polverino, A. & Wigler, M. Proc. natn. Acad. Sci. U.S.A. 90, 6213–6217 (1993). (10.1073/pnas.90.13.6213) / Proc. natn. Acad. Sci. U.S.A. by L Van Aelst (1993)
Vojtek, A. B., Hollenberg, S. M. & Cooper, J. A. Cell 74, 205–214 (1993). (10.1016/0092-8674(93)90307-C) / Cell by AB Vojtek (1993)
Zhang, X.-F. et al. Nature 364, 308–313 (1993). (10.1038/364308a0) / Nature by X-F Zhang (1993)
Warne, P. H., Vicinia, P. R. & Downward, J. Nature 364, 352–355 (1993). (10.1038/364352a0) / Nature by PH Warne (1993)
Feig, L. A. Science 260, 767–768 (1993). (10.1126/science.8484117) / Science by LA Feig (1993)
Simon, M. A., Bowtell, D. D. L., Dodson, G. S., Laverty, T. R. & Rubin, G. M. Cell 67, 701–716 (1991). (10.1016/0092-8674(91)90065-7) / Cell by MA Simon (1991)
Bonfini, L., Karlovich, C. A., Dasgupta, C. & Banerjee, U. Science 255, 603–606 (1992). (10.1126/science.1736363) / Science by L Bonfini (1992)
Bowtell, D., Fu, P., Simon, M. & Senior, P. Proc. natn. Acad. Sci. U.S.A. 89, 6511–6515 (1992). (10.1073/pnas.89.14.6511) / Proc. natn. Acad. Sci. U.S.A. by D Bowtell (1992)
McCormick, F. Nature 363, 15–16 (1993). (10.1038/363015a0) / Nature by F McCormick (1993)
Lowenstein, E. J. et al. Cell 70, 431–442 (1992). (10.1016/0092-8674(92)90167-B) / Cell by EJ Lowenstein (1992)
Matuoka, K., Shibata, M., Yamakawa, A. & Takenawa, T. Proc. natn. Acad. Sci. U.S.A. 89, 9015–9019 (1992). (10.1073/pnas.89.19.9015) / Proc. natn. Acad. Sci. U.S.A. by K Matuoka (1992)
Clark, S. G., Stern, M. J. & Horvitz, H. R. Nature 356, 340–344 (1992). (10.1038/356340a0) / Nature by SG Clark (1992)
Schlessinger, J. & Ullrich, A. Neuron 9, 383–391 (1992). (10.1016/0896-6273(92)90177-F) / Neuron by J Schlessinger (1992)
Pawson, T. & Gish, G. D. Cell 71, 359–362 (1992). (10.1016/0092-8674(92)90504-6) / Cell by T Pawson (1992)
Kyriakis, J. M. et al. Nature 358, 417–421 (1992). (10.1038/358417a0) / Nature by JM Kyriakis (1992)
Howe, L. R. et al. Cell 71, 335–342 (1992). (10.1016/0092-8674(92)90361-F) / Cell by LR Howe (1992)
Hughes, D. A., Ashworth, A. & Marshall, C. J. Nature 364, 349–352 (1993). (10.1038/364349a0) / Nature by DA Hughes (1993)
Crews, C. M., Alessandrini, A. & Erikson, R. L. Science 258, 478–480 (1992). (10.1126/science.1411546) / Science by CM Crews (1992)
Pelech, S. L. & Sanghera, J. S. Trends biochem. Sci. 17, 233–238 (1992). (10.1016/S0968-0004(00)80005-5) / Trends biochem. Sci. by SL Pelech (1992)
Gutman, A. & Wasylyk, B. Trends Genet. 7, 49–54 (1991). (10.1016/0168-9525(91)90231-E) / Trends Genet. by A Gutman (1991)
Hunter, T. & Karin, M. Cell 70, 375–387 (1992). (10.1016/0092-8674(92)90162-6) / Cell by T Hunter (1992)
Montminy, M. Science 261, 1694–1695 (1993). (10.1126/science.8397444) / Science by M Montminy (1993)

Dates

Type	When
Created	22 years ago (Aug. 11, 2003, 9:17 p.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 10:46 p.m.)
Indexed	1 month, 2 weeks ago (July 12, 2025, 6:57 p.m.)
Issued	31 years, 10 months ago (Oct. 1, 1993)
Published	31 years, 10 months ago (Oct. 1, 1993)
Published Print	31 years, 10 months ago (Oct. 1, 1993)

Funders 0

None

BibTeX

@article{Egan_1993, title={The pathway to signal achievement}, volume={365}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/365781a0}, DOI={10.1038/365781a0}, number={6449}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Egan, Sean E. and Weinberg, Robert A.}, year={1993}, month=oct, pages={781–783} }

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