DOI: 10.1038/365464a0. Crystal structure of the DsbA protein required for disulphide bond formation in vivo

Crystal structure of the DsbA protein required for disulphide bond formation in vivo

10.1038/365464a0

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Martin, J. L., Bardwell, J. C. A., & Kuriyan, J. (1993). Crystal structure of the DsbA protein required for disulphide bond formation in vivo. Nature, 365(6445), 464â468.

Authors 3

Jennifer L. Martin (first)
James C. A. Bardwell (additional)
John Kuriyan (additional)

References 35 Referenced 325

Creighton, T. E. Meth. Enzym. 107, 305–329 (1984). (10.1016/0076-6879(84)07021-X) / Meth. Enzym. by TE Creighton (1984)
Weissman, J. S. & Kim, P. S. Cell 71, 841–851 (1992). (10.1016/0092-8674(92)90559-U) / Cell by JS Weissman (1992)
Bardwell, J. C. A., McGovern, K. & Beckwith, J. Cell 67, 581–589 (1991). (10.1016/0092-8674(91)90532-4) / Cell by JCA Bardwell (1991)
Kamitani, S., Akiyama, Y. & Ito, K. EMBO J. 11, 57–62 (1992). (10.1002/j.1460-2075.1992.tb05027.x) / EMBO J. by S Kamitani (1992)
Eklund, H., Gleason, F. S. & Holmgren, A. Proteins Struct. Funct. Genet. 11, 13–28 (1991). (10.1002/prot.340110103) / Proteins Struct. Funct. Genet. by H Eklund (1991)
Lovejoy, B. et al. Science 259, 1288–1293 (1993). (10.1126/science.8446897) / Science by B Lovejoy (1993)
Brown, L. R. et al. J. molec. Biol. 231, 800–816 (1993). (10.1006/jmbi.1993.1327) / J. molec. Biol. by LR Brown (1993)
Katti, S. K., LeMaster, D. M. & Eklund, H. J. molec. Biol. 212, 167–184 (1990). (10.1016/0022-2836(90)90313-B) / J. molec. Biol. by SK Katti (1990)
Tomb, J.-F. Proc. natn. Acad. Sci. U.S.A. 89, 10252–10256 (1992). (10.1073/pnas.89.21.10252) / Proc. natn. Acad. Sci. U.S.A. by J-F Tomb (1992)
Ellis, L. B. M., Saurugger, P. & Woodward, C. Biochemistry 31, 4882–4891 (1992). (10.1021/bi00135a020) / Biochemistry by LBM Ellis (1992)
Eklund, H. et al. J. molec. Biol. 228, 596–618 (1992). (10.1016/0022-2836(92)90844-A) / J. molec. Biol. by H Eklund (1992)
Sodano, P. et al. J. molec. Biol. 221, 1311–1324 (1991). (10.1016/0022-2836(91)90935-Y) / J. molec. Biol. by P Sodano (1991)
Xia, T.-H. et al. Prot. Sci. 1, 310–321 (1992). (10.1002/pro.5560010302) / Prot. Sci. by T-H Xia (1992)
Epp, O., Ladenstein, R. & Wendel, A. Eur. J. Biochem. 133, 51–69 (1983). (10.1111/j.1432-1033.1983.tb07429.x) / Eur. J. Biochem. by O Epp (1983)
Reinemer, P. et al. EMBO J. 10, 1997–2005 (1991). (10.1002/j.1460-2075.1991.tb07729.x) / EMBO J. by P Reinemer (1991)
Ji, X., Zhang, P., Armstrong, R. N. & Gilliland, G. L. Biochemistry 31, 10169–10184 (1992). (10.1021/bi00157a004) / Biochemistry by X Ji (1992)
Thornton, J. M. J. molec. Biol. 151, 261–287 (1981). (10.1016/0022-2836(81)90515-5) / J. molec. Biol. by JM Thornton (1981)
Bardwell, J. C. A. et al. Proc. natn. Acad. Sci. U.S.A. 90, 11038–1042 (1993). (10.1073/pnas.90.3.1038) / Proc. natn. Acad. Sci. U.S.A. by JCA Bardwell (1993)
Dailey, F. E. & Berg, H. C. Proc. natn. Acad. Sci. U.S.A. 90, 1043–1047 (1993). (10.1073/pnas.90.3.1043) / Proc. natn. Acad. Sci. U.S.A. by FE Dailey (1993)
Zapun, A., Bardwell, J. C. A. & Creighton, T. E. Biochemistry (in the press).
Wünderlich, M., Jaenicke, R. & Glockshuber, R. J. molec. Biol. (in the press).
Wünderlich, M. & Glockshuber, R. Prot. Sci. 2, 717–726 (1993). (10.1002/pro.5560020503) / Prot. Sci. by M Wünderlich (1993)
Krause, G., Lundström, J., Lopez-Barea, J., Pueyo de La Cuesta, C. & Holmgren, A. J. biol. Chem. 266, 9494–9500 (1991). (10.1016/S0021-9258(18)92848-6) / J. biol. Chem. by G Krause (1991)
Martin, J. L., Waksman, G., Bardwell, J. C. A., Beckwith, J. & Kuriyan, J. J. molec. Biol. 230, 1097–1100 (1993). (10.1006/jmbi.1993.1226) / J. molec. Biol. by JL Martin (1993)
Edman, J. C., Ellis, L., Blacher, R. W., Roth, R. R. & Rutter, W. J. Nature 317, 267–270 (1985). (10.1038/317267a0) / Nature by JC Edman (1985)
Wilson, K. S. Acta crystallogr. B34, 1599–1608 (1978). (10.1107/S0567740878006135) / Acta crystallogr. by KS Wilson (1978)
Terwilliger, T. C. & Eisenberg, D. Acta crystallogr. A39, 813–817 (1983). (10.1107/S0108767383001592) / Acta crystallogr. by TC Terwilliger (1983)
Weis, W. I., Kahn, R., Fourme, R., Drickamer, K. & Hendrickson, W. A. Science 254, 1608–1615 (1991). (10.1126/science.1721241) / Science by WI Weis (1991)
Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. Acta cystallogr. A47, 110–119 (1991). (10.1107/S0108767390010224) / Acta cystallogr. by TA Jones (1991)
Wang, B. C. Meth. Enzym. 115, 90–112 (1985). (10.1016/0076-6879(85)15009-3) / Meth. Enzym. by BC Wang (1985)
Zhang, K. Y. J. & Main, P. Acta crystallogr. A46, 41–46 (1990). (10.1107/S0108767389009311) / Acta crystallogr. by KYJ Zhang (1990)
Brünger, A. T. X-PLOR (Version 3.1) Manual (The Howard Hughes Medical Institute and Department of Molecular Biophysics and Biochemistry, Yale University, 260 Whitney Avenue, New Haven, CT 06511, 1992). / X-PLOR (Version 3.1) Manual by AT Brünger (1992)
Bernstein, F. C. et al. J. molec. Biol. 112, 535–542 (1977). (10.1016/S0022-2836(77)80200-3) / J. molec. Biol. by FC Bernstein (1977)
Nicholls, A., Sharp, K. A. & Honig, B. Proteins Struct. Funct. Genet. 11, 281–296 (1991). (10.1002/prot.340110407) / Proteins Struct. Funct. Genet. by A Nicholls (1991)
Hendrickson, W. A. Science 254, 51–58 (1991). (10.1126/science.1925561) / Science by WA Hendrickson (1991)

Dates

Type	When
Created	22 years ago (Aug. 11, 2003, 8:39 p.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 10:43 p.m.)
Indexed	2 months ago (July 1, 2025, 9:08 p.m.)
Issued	32 years ago (Sept. 1, 1993)
Published	32 years ago (Sept. 1, 1993)
Published Print	32 years ago (Sept. 1, 1993)

Funders 0

None

BibTeX

@article{Martin_1993, title={Crystal structure of the DsbA protein required for disulphide bond formation in vivo}, volume={365}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/365464a0}, DOI={10.1038/365464a0}, number={6445}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Martin, Jennifer L. and Bardwell, James C. A. and Kuriyan, John}, year={1993}, month=sep, pages={464–468} }

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