DOI: 10.1038/35098106. Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly

Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly

10.1038/35098106

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Luo, M.-J., Zhou, Z., Magni, K., Christoforides, C., Rappsilber, J., Mann, M., & Reed, R. (2001). Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature, 413(6856), 644â647.

Authors 7

Ming-Juan Luo (first)
Zhaolan Zhou (additional)
Keith Magni (additional)
Claudine Christoforides (additional)
Juri Rappsilber (additional)
Matthias Mann (additional)
Robin Reed (additional)

References 23 Referenced 316

Luo, M. & Reed, R. Splicing is required for rapid and efficient mRNA export in metazoans. Proc. Natl Acad. Sci. USA 96, 14937–14942 (1999). (10.1073/pnas.96.26.14937) / Proc. Natl Acad. Sci. USA by M Luo (1999)
Zhou, Z. et al. The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature 407, 401–405 (2000). (10.1038/35030160) / Nature by Z Zhou (2000)
Huang, Y. & Steitz, J. A. Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA. Mol. Cell 7, 899–905 (2001). (10.1016/S1097-2765(01)00233-7) / Mol. Cell by Y Huang (2001)
Rodrigues, J. P. et al. REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus. Proc. Natl Acad. Sci. USA 98, 1030–1035 (2001). (10.1073/pnas.98.3.1030) / Proc. Natl Acad. Sci. USA by JP Rodrigues (2001)
Le Hir, H., Izaurralde, E., Maquat, L. E. & Moore, M. J. The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions. EMBO J. 19, 6860–6869 (2000). (10.1093/emboj/19.24.6860) / EMBO J. by H Le Hir (2000)
Kataoka, N. et al. Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm. Mol. Cell 6, 673–682 (2000). (10.1016/S1097-2765(00)00065-4) / Mol. Cell by N Kataoka (2000)
Fleckner, J., Zhang, M., Valcarcel, J. & Green, M. R. U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction. Genes Dev. 11, 1864–1872 (1997). (10.1101/gad.11.14.1864) / Genes Dev. by J Fleckner (1997)
Kistler, A. L. & Guthrie, C. Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase. Genes Dev. 15, 42–49 (2001). (10.1101/gad.851301) / Genes Dev. by AL Kistler (2001)
Libri, D., Graziani, N., Saguez, C. & Boulay, J. Multiple roles for the yeast SUB2/yUAP56 gene in splicing. Genes Dev. 15, 36–41 (2001). (10.1101/gad.852101) / Genes Dev. by D Libri (2001)
Zhang, M. & Green, M. R. Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56. Genes Dev. 15, 30–35 (2001). (10.1101/gad.851701) / Genes Dev. by M Zhang (2001)
Staley, J. P. & Guthrie, C. Mechanical devices of the spliceosome: motors, clocks, springs, and things. Cell 92, 315–326 (1998). (10.1016/S0092-8674(00)80925-3) / Cell by JP Staley (1998)
Strasser, K. & Hurt, E. Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J. 19, 410–420 (2000). (10.1093/emboj/19.3.410) / EMBO J. by K Strasser (2000)
Kim, V. N. et al. The Y14 protein communicates to the cytoplasm the position of exon–exon junctions. EMBO J. 20, 2062–2068 (2001). (10.1093/emboj/20.8.2062) / EMBO J. by VN Kim (2001)
Conti, E. & Izaurralde, E. Nucleocytoplasmic transport enters the atomic age. Curr. Opin. Cell Biol. 13, 310–319 (2001). (10.1016/S0955-0674(00)00213-1) / Curr. Opin. Cell Biol. by E Conti (2001)
Virbasius, C. M., Wagner, S. & Green, M. R. A human nuclear-localized chaperone that regulates dimerization, DNA binding, and transcriptional activity of bZIP proteins. Mol. Cell 4, 219–228 (1999). (10.1016/S1097-2765(00)80369-X) / Mol. Cell by CM Virbasius (1999)
Bruhn, L., Munnerlyn, A. & Grosschedl, R. ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRα enhancer function. Genes Dev. 11, 640–653 (1997). (10.1101/gad.11.5.640) / Genes Dev. by L Bruhn (1997)
Moazed, D., Kistler, A., Axelrod, A., Rine, J. & Johnson, A. D. Silent information regulator protein complexes in Saccharomyces cerevisiae: a SIR2/SIR4 complex and evidence for a regulatory domain in SIR4 that inhibits its interaction with SIR3. Proc. Natl Acad. Sci. USA 94, 2186–2191 (1997). (10.1073/pnas.94.6.2186) / Proc. Natl Acad. Sci. USA by D Moazed (1997)
Izaurralde, E., Kutay, U., von Kobbe, C., Mattaj, I. W. & Gorlich, D. The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J. 16, 6535–6547 (1997). (10.1093/emboj/16.21.6535) / EMBO J. by E Izaurralde (1997)
Hamm, J. & Mattaj, I. W. Monomethylated cap structures facilitate RNA export from the nucleus. Cell 63, 109–118 (1990). (10.1016/0092-8674(90)90292-M) / Cell by J Hamm (1990)
Das, R., Zhou, Z. & Reed, R. Functional association of U2 snRNP with the ATP-independent spliceosomal complex E. Mol. Cell 5, 779–787 (2000). (10.1016/S1097-2765(00)80318-4) / Mol. Cell by R Das (2000)
Wichmann, I., Garcia-Lozano, J. R., Respaldiza, N., Gonzalez-Escribano, M. F. & Nunez-Roldan, A. Autoantibodies to transcriptional regulation proteins DEK and ALY in a patient with systemic lupus erythematosus. Hum. Immunol. 60, 57–62 (1999). (10.1016/S0198-8859(98)00085-8) / Hum. Immunol. by I Wichmann (1999)
Vorm, O., Roepstorff, P. & Mann, M. Improved resolution and very high sensitivity in MALDI TDf of matrix surfaces made by fast evaporation. Anal. Chem. 66, 3281–3287 (1994). (10.1021/ac00091a044) / Anal. Chem. by O Vorm (1994)
Sträßer, K. & Hurt, E. Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p.. Nature 413, 648–652 (1999). (10.1038/35098113) / Nature by K Sträßer (1999)

Dates

Type	When
Created	22 years, 11 months ago (Sept. 24, 2002, 1:02 p.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 10:12 p.m.)
Indexed	5 days, 9 hours ago (Aug. 31, 2025, 6:33 a.m.)
Issued	23 years, 11 months ago (Oct. 1, 2001)
Published	23 years, 11 months ago (Oct. 1, 2001)
Published Print	23 years, 11 months ago (Oct. 1, 2001)

Funders 0

None

BibTeX

@article{Luo_2001, title={Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly}, volume={413}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/35098106}, DOI={10.1038/35098106}, number={6856}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Luo, Ming-Juan and Zhou, Zhaolan and Magni, Keith and Christoforides, Claudine and Rappsilber, Juri and Mann, Matthias and Reed, Robin}, year={2001}, month=oct, pages={644–647} }

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