Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells
10.1038/35059110
Crossref journal-article
Springer Science and Business Media LLC
Nature (297)
Bibliography

Mandelboim, O., Lieberman, N., Lev, M., Paul, L., Arnon, T. I., Bushkin, Y., Davis, D. M., Strominger, J. L., Yewdell, J. W., & Porgador, A. (2001). Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells. Nature, 409(6823), 1055–1060.

Authors 10
  1. Ofer Mandelboim (first)
  2. Niva Lieberman (additional)
  3. Marianna Lev (additional)
  4. Lada Paul (additional)
  5. Tal I. Arnon (additional)
  6. Yuri Bushkin (additional)
  7. Daniel M. Davis (additional)
  8. Jack L. Strominger (additional)
  9. Jonathan W. Yewdell (additional)
  10. Angel Porgador (additional)
References 29 Referenced 745
  1. Trinchieri, G. Biology of natural killer cells. Adv. Immunol. 47, 187–376 (1989). (10.1016/S0065-2776(08)60664-1) / Adv. Immunol. by G Trinchieri (1989)
  2. Lanier, L. L. NK cell receptors. Annu. Rev. Immunol. 16, 359–393 (1998). (10.1146/annurev.immunol.16.1.359) / Annu. Rev. Immunol. by LL Lanier (1998)
  3. Ljunggren, H. G. & Karre, K. In search of the ‘missing self’: MHC molecules and NK recognition. Immunol. Today 11, 7–10 (1990). (10.1016/0167-5699(90)90097-S) / Immunol. Today by HG Ljunggren (1990)
  4. Davis, D. M. et al. The human natural killer cell immune synapse. Proc. Natl Acad. Sci. USA 96, 15062–15067 (1999). (10.1073/pnas.96.26.15062) / Proc. Natl Acad. Sci. USA by DM Davis (1999)
  5. Braud, V. M. et al. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391, 795–799 (1998). (10.1038/35869) / Nature by VM Braud (1998)
  6. Colonna, M. & Samaridis, J. Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells. Science 268, 405–408 (1995). (10.1126/science.7716543) / Science by M Colonna (1995)
  7. Wagtmann, N. et al. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains. Immunity 2, 439–449 (1995). (10.1016/1074-7613(95)90025-X) / Immunity by N Wagtmann (1995)
  8. D'Andrea, A. et al. Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J. Immunol. 155, 2306–2310 (1995). (10.4049/jimmunol.155.5.2306) / J. Immunol. by A D'Andrea (1995)
  9. Bottino, C., Biassoni, R., Millo R., Moretta, L. & Moretta, A. The human natural cytotoxicity receptors (NCR) that induce HLA class I independent NK cell triggering. Hum. Immunol. 61, 1–6 (2000). (10.1016/S0198-8859(99)00162-7) / Hum. Immunol. by C Bottino (2000)
  10. Mandelboim, O. et al. Human CD16 as a lysis receptor mediating direct natural killer (NK) cell cytotoxicity. Proc. Natl Acad. Sci. USA 96, 5640–5644 (1999). (10.1073/pnas.96.10.5640) / Proc. Natl Acad. Sci. USA by O Mandelboim (1999)
  11. Pende, D. et al. Identification and molecular characterization of NKp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells. J. Exp. Med. 190, 1505–1516 (1999). (10.1084/jem.190.10.1505) / J. Exp. Med. by D Pende (1999)
  12. Cantoni, C. et al. NKp44, A triggering receptor involved in tumor cell lysis by activated human natural killer cells, is a novel member of the immunoglobulin superfamily. J. Exp. Med. 189, 787–796 (1999). (10.1084/jem.189.5.787) / J. Exp. Med. by C Cantoni (1999)
  13. Biassoni, R. et al. The murine homologue of the human NKp46, a triggering receptor involved in the induction of natural cytotoxicity. Eur. J. Immunol. 29, 1014–1020 (1999). (10.1002/(SICI)1521-4141(199903)29:03<1014::AID-IMMU1014>3.0.CO;2-O) / Eur. J. Immunol. by R Biassoni (1999)
  14. Pessino, A. et al. Molecular cloning of NKp46: novel member of the immunoglobulin superfamily involved in triggering of natural cytotocxicity. J. Exp. Med. 188, 953–960 (1998). (10.1084/jem.188.5.953) / J. Exp. Med. by A Pessino (1998)
  15. Sivori, S. et al. NKp46 is the major triggering receptor involved in the natural cytotoxicity of fresh or cultured human NK cells. Correlation between surface density of NKp46 and natural cytotoxicity against autologous, allogeneic or xenogeneic target cells. Eur. J. Immunol. 29, 1656–1666 (1999). (10.1002/(SICI)1521-4141(199905)29:05<1656::AID-IMMU1656>3.0.CO;2-1) / Eur. J. Immunol. by S Sivori (1999)
  16. Alsheikhly, A. et al. Sendai-virus-induced cell-mediated cytotoxicity in vitro. The role of viral glycoproteins in cell-mediated cytotoxicity. Scand. J. Immunol. 17, 129–138 (1983). (10.1111/j.1365-3083.1983.tb00775.x) / Scand. J. Immunol. by A Alsheikhly (1983)
  17. Alsheikhly, A. R., Orvell, C., Andersson, T. & Perlmann, P. The role of serologically defined epitopes on mumps virus HN–glycoprotein in the induction of virus-dependent cell-mediated cytotoxicity. Analysis with monoclonal antibodies. Scand. J. Immunol. 22, 529–538 (1985). (10.1111/j.1365-3083.1985.tb01912.x) / Scand. J. Immunol. by AR Alsheikhly (1985)
  18. Maisner, A. & Herrler, G. Membrane cofactor protein with different types of N-glycans can serve as measles virus receptor. Virology 210, 479–481 (1995). (10.1006/viro.1995.1365) / Virology by A Maisner (1995)
  19. Varki, A. Sialic acids as ligands in recognition phenomena. FASEB J. 11, 248–255 (1997). (10.1096/fasebj.11.4.9068613) / FASEB J. by A Varki (1997)
  20. Weis, W. et al. Structure of the influenza virus hemagglutinin complexed with its receptor, sialic acid. Nature 333, 426–431 (1988). (10.1038/333426a0) / Nature by W Weis (1988)
  21. De Lau, W. B., Kuipers, J., Voshol, H., Clevers, H. & Bast, B. J. HB4 antibody recognizes a carbohydrate structure on lymphocyte surface proteins related to HB6, CDw75, and CD76 antigens. J. Immunol. 150, 4911–4919 (1993). (10.4049/jimmunol.150.11.4911) / J. Immunol. by WB De Lau (1993)
  22. Pinola, M., Renkonen, R., Majuri, M. L., Tiisala, S. & Saksela, E. Characterization of the E-selectin ligand on NK cells. J. Immunol. 152, 3586–3594 (1994). (10.4049/jimmunol.152.7.3586) / J. Immunol. by M Pinola (1994)
  23. Mandelboim, O. et al. Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules. J. Exp. Med. 184, 913–922 (1996). (10.1084/jem.184.3.913) / J. Exp. Med. by O Mandelboim (1996)
  24. Peterhans, E., Bachi, T. & Yewdell, J. W. Evidence for different receptor sites in mouse spleen cells for the SV hemagglutinin-neuraminidase (HN) and fusion (F) glycoproteins. Virology 128, 366–376 (1983). (10.1016/0042-6822(83)90263-5) / Virology by E Peterhans (1983)
  25. Yewdell, J. W. & Gerhard, W. Delineation of four antigenic sites on a paramyxovirus glycoprotein via which antibodies mediate distinct antiviral activities. J. Immunol. 128, 2670–2675 (1982). (10.4049/jimmunol.128.6.2670) / J. Immunol. by JW Yewdell (1982)
  26. Yewdell, J. W., Gerhard, W. & Bachi, T. Monoclonal anti-hemagglutinin antibodies detect irreversible antigenic alterations that coincide with the acid activation of influenza virus A/PR/8/34-mediated hemolysis. J. Virol. 48, 239–248 (1983). (10.1128/JVI.48.1.239-248.1983) / J. Virol. by JW Yewdell (1983)
  27. Porgador, A., Mandelboim, O., Restifo, N. P., Strominger, J. L. Natural killer cell lines kill autologous beta2-microglobulin-deficient melanoma cells: implications for cancer immunotherapy. Proc. Natl Acad. Sci. USA 94, 13140–13145 (1997). (10.1073/pnas.94.24.13140) / Proc. Natl Acad. Sci. USA by A Porgador (1997)
  28. Brand, C. M. & Skehel, J. J. Crystalline antigen from the influenza virus envelope. Nature 238, 145–147 (1972). (10.1038/238145a0) / Nature by CM Brand (1972)
  29. Irving, B. A. & Weiss, A. The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways. Cell 64, 891–901 (1991). (10.1016/0092-8674(91)90314-O) / Cell by BA Irving (1991)
Dates
Type When
Created 22 years, 11 months ago (Sept. 13, 2002, 2:08 p.m.)
Deposited 2 years, 3 months ago (May 16, 2023, 9:50 p.m.)
Indexed 1 week, 4 days ago (Aug. 23, 2025, 12:58 a.m.)
Issued 24 years, 7 months ago (Feb. 1, 2001)
Published 24 years, 7 months ago (Feb. 1, 2001)
Published Print 24 years, 7 months ago (Feb. 1, 2001)
Funders 0

None

@article{Mandelboim_2001, title={Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells}, volume={409}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/35059110}, DOI={10.1038/35059110}, number={6823}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Mandelboim, Ofer and Lieberman, Niva and Lev, Marianna and Paul, Lada and Arnon, Tal I. and Bushkin, Yuri and Davis, Daniel M. and Strominger, Jack L. and Yewdell, Jonathan W. and Porgador, Angel}, year={2001}, month=feb, pages={1055–1060} }