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El-Omar, E. M., Carrington, M., Chow, W.-H., McColl, K. E. L., Bream, J. H., Young, H. A., Herrera, J., Lissowska, J., Yuan, C.-C., Rothman, N., Lanyon, G., Martin, M., Fraumeni, J. F., & Rabkin, C. S. (2000). Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature, 404(6776), 398–402.

Authors 14
  1. Emad M. El-Omar (first)
  2. Mary Carrington (additional)
  3. Wong-Ho Chow (additional)
  4. Kenneth E. L. McColl (additional)
  5. Jay H. Bream (additional)
  6. Howard A. Young (additional)
  7. Jesus Herrera (additional)
  8. Jolanta Lissowska (additional)
  9. Chiu-Chin Yuan (additional)
  10. Nathaniel Rothman (additional)
  11. George Lanyon (additional)
  12. Maureen Martin (additional)
  13. Joseph F. Fraumeni (additional)
  14. Charles S. Rabkin (additional)
References 30 Referenced 1,801
  1. Blaser, M. J. Helicobacter pylori and gastric diseases. Br. Med. J. 316, 1507–1510 (1998). (10.1136/bmj.316.7143.1507) / Br. Med. J. by MJ Blaser (1998)
  2. El-Omar, E. et al. Helicobacter pylori infection and abnormalities of acid secretion in patients with duodenal ulcer disease. Gastroenterology 109, 681–691 ( 1995). (10.1016/0016-5085(95)90374-7) / Gastroenterology by E El-Omar (1995)
  3. El-Omar, E. et al. Helicobacter pylori infectin and chronic gastric acid hyposecretion. Gastroenterology 113, 15– 24 (1997). (10.1016/S0016-5085(97)70075-1) / Gastroenterology by E El-Omar (1997)
  4. Correa, P. Human gastric carcinogenesis: a multistep and multifactorial process—First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res. 52, 6735–6740 (1992). / Cancer Res. by Correa, P. (1992)
  5. Dinarello, C. A. Biologic basis for interleukin-1 in disease. Blood 87, 2095–2147 (1996). (10.1182/blood.V87.6.2095.bloodjournal8762095) / Blood by CA Dinarello (1996)
  6. Wallace, J. L., Cucala, M., Mugridge, K. & Parente, L. Secretagogue-specific effects of interleukin-1 on gastric acid secretion. Am. J. Physiol. 261, G559–G564 ( 1991). / Am. J. Physiol. by JL Wallace (1991)
  7. Beales, I. L. & Calam, J. Interleukin 1 beta and tumour necrosis factor alpha inhibit acid secretion in cultured rabbit parietal cells by multiple pathways. Gut 42, 227–234 (1998). (10.1136/gut.42.2.227) / Gut by IL Beales (1998)
  8. Parkin, D. M., Pisani, P. & Ferlay, J. Estimates of the worldwide incidence of 25 major cancers in 1990. Int. J. Cancer 80, 827– 841 (1999). (10.1002/(SICI)1097-0215(19990315)80:6<827::AID-IJC6>3.0.CO;2-P) / Int. J. Cancer by DM Parkin (1999)
  9. Sipponen, P. Gastric cancer—a long-term consequence of Helicobactor pylori infection? Scand. J. Gastroenterol. 201, (suppl.), 24–27 (1994). (10.3109/00365529409105356) / Scand. J. Gastroenterol. by P Sipponen (1994)
  10. Yamaoka, Y. et al. Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: studies in four different countries. J. Clin. Microbiol. 37, 2274– 2279 (1999). (10.1128/JCM.37.7.2274-2279.1999) / J. Clin. Microbiol. by Y Yamaoka (1999)
  11. Hansson, L. E. et al. The risk of stomach cancer in patients with gastric or duodenal ulcer disease. N. Engl. J. Med. 335, 242 –249 (1996). (10.1056/NEJM199607253350404) / N. Engl. J. Med. by LE Hansson (1996)
  12. Kuipers, E. J. et al. Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N. Engl. J. Med. 334, 1018– 1022 (1996). (10.1056/NEJM199604183341603) / N. Engl. J. Med. by EJ Kuipers (1996)
  13. Noach, L. A. et al. Mucosal tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-8 production in patients with Helicobacter pylori infection. Scand. J. Gastroenterol. 29, 425– 429 (1994). (10.3109/00365529409096833) / Scand. J. Gastroenterol. by LA Noach (1994)
  14. Basso, D. et al. Helicobacter pylori infection enhances mucosal interleukin-1 beta, interleukin-6, and the soluble receptor of interleukin-2. Int. J. Clin. Lab. Res. 26, 207–210 (1996). (10.1007/BF02592984) / Int. J. Clin. Lab. Res. by D Basso (1996)
  15. Jung, H. C., Kim, J. M., Song, I. S. & Kim, C. Y. Helicobacter pylori induces an array of pro-inflammatory cytokines in human gastric epithelial cells: quantification of mRNA for interleukin-8, -1 alpha/beta, granulocyte-macrophage colony-stimulating factor, monocyte chemoattractant protein-1 and tumour necrosis factor-alpha. J. Gastroenterol. Hepatol. 12, 473–480 ( 1997). (10.1111/j.1440-1746.1997.tb00469.x) / J. Gastroenterol. Hepatol. by HC Jung (1997)
  16. Wolfe, M. M. & Nompleggi, D. J. Cytokine inhibition of gastric acid secretion—a little goes a long way. Gastroenterology 102, 2177–2178 ( 1992). (10.1016/0016-5085(92)90360-B) / Gastroenterology by MM Wolfe (1992)
  17. Bidwell, J. L. et al. Cytokine gene polymorphism in human disease: on-line databases. 〈http://www.pam.bris.ac.uk/services/GAI/cytokine4.htm.〉
  18. Pociot, F. et al. A TaqI polymorphisms in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro. Eur. J. Clin. Invest. 22, 396–402 (1992). (10.1111/j.1365-2362.1992.tb01480.x) / Eur. J. Clin. Invest. by F Pociot (1992)
  19. Santtila, S., Savinainen, K. & Hurme, M. Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro. Scand. J. Immunol. 47, 195–198 ( 1998). (10.1046/j.1365-3083.1998.00300.x) / Scand. J. Immunol. by S Santtila (1998)
  20. Andus, T. et al. Imbalance of the interleukin 1 system in colonic mucosa—association with intestinal inflammation and interleukin 1 receptor antagonist genotype 2. Gut 41, 651–657 (1997). (10.1136/gut.41.5.651) / Gut by T Andus (1997)
  21. Danis, V. A., Millington, M., Hyland, V. J. & Grennan, D. Cytokine production by normal human monocytes: inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism. Clin. Exp. Immunol. 99, 303–310 (1995). (10.1111/j.1365-2249.1995.tb05549.x) / Clin. Exp. Immunol. by VA Danis (1995)
  22. Tountas, N. A. et al. Functional and ethnic association of allele 2 of the interleukin-1 receptor antagonist gene in ulcerative colitis. Gastroenterology 117, 806–813 ( 1999). (10.1016/S0016-5085(99)70338-0) / Gastroenterology by NA Tountas (1999)
  23. El-Omar, E. M. et al. Increased prevalence of precancerous changes in relatives of gastric cancer patients: critical role of H. pylori. Gastroenterology 118, 22–30 (2000). (10.1016/S0016-5085(00)70410-0) / Gastroenterology by EM El-Omar (2000)
  24. Chow, H. W. et al. Risk of stomach cancer in relation to consumption of cigarettes, alcohol, tea and coffee in Warsaw, Poland. Int. J. Cancer 81, 871–876 (1999). (10.1002/(SICI)1097-0215(19990611)81:6<871::AID-IJC6>3.0.CO;2-#) / Int. J. Cancer by HW Chow (1999)
  25. Cox, A., Camp, N. J., Nicklin, M. J., Di Giovine, F. S. & Duff, G. W. An analysis of linkage disequilibrium in the interleukin-1 gene cluster, using a novel grouping method for multiallelic markers. Am. J. Hum. Genet. 62, 1180–1188 (1998). (10.1086/301817) / Am. J. Hum. Genet. by A Cox (1998)
  26. Stockbruegger, R. W. et al. Pernicious anaemia, intragastric bacterial overgrowth, and possible consequences. Scand. J. Gastroenterol. 19, 355–364 (1984). (10.1080/00365521.1984.12005735) / Scand. J. Gastroenterol. by RW Stockbruegger (1984)
  27. Ruiz, B. et al. Vitamin C concentration in gastric juice before and after anti- Helicobacter pylori treatment. Am. J. Gastroenterol. 89, 533–539 (1994). / Am. J. Gastroenterol. by B Ruiz (1994)
  28. Carrington, M. et al. Typing of HLA-DQA1 and DQB1 using DNA single-strand conformation polymorphism. Hum. Immunol. 33, 208– 212 (1992). (10.1016/0198-8859(92)90073-V) / Hum. Immunol. by M Carrington (1992)
  29. Yu, C. R. et al. Differential utilization of Janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and IFN-alpha. J. Immunol. 157 , 126–137 (1996). (10.4049/jimmunol.157.1.126) / J. Immunol. by CR Yu (1996)
  30. Royall, R. M. Model robust confidence intervals using maximum likelihood estimators. Int. Stat. Rev. 54, 221–226 (1986). (10.2307/1403146) / Int. Stat. Rev. by RM Royall (1986)
Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:41 a.m.)
Deposited 2 years, 3 months ago (May 16, 2023, 9:52 p.m.)
Indexed 1 day, 13 hours ago (Sept. 4, 2025, 10:04 a.m.)
Issued 25 years, 5 months ago (March 23, 2000)
Published 25 years, 5 months ago (March 23, 2000)
Published Print 25 years, 5 months ago (March 23, 2000)
Funders 0

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@article{El_Omar_2000, title={Interleukin-1 polymorphisms associated with increased risk of gastric cancer}, volume={404}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/35006081}, DOI={10.1038/35006081}, number={6776}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={El-Omar, Emad M. and Carrington, Mary and Chow, Wong-Ho and McColl, Kenneth E. L. and Bream, Jay H. and Young, Howard A. and Herrera, Jesus and Lissowska, Jolanta and Yuan, Chiu-Chin and Rothman, Nathaniel and Lanyon, George and Martin, Maureen and Fraumeni, Joseph F. and Rabkin, Charles S.}, year={2000}, month=mar, pages={398–402} }