HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes
10.1038/35004038
Crossref journal-article
Springer Science and Business Media LLC
Nature Cell Biology (297)
Bibliography

Piguet, V., Wan, L., Borel, C., Mangasarian, A., Demaurex, N., Thomas, G., & Trono, D. (2000). HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes. Nature Cell Biology, 2(3), 163–167.

Authors 7
  1. Vincent Piguet (first)
  2. Lei Wan (additional)
  3. Christelle Borel (additional)
  4. Aram Mangasarian (additional)
  5. Nicolas Demaurex (additional)
  6. Gary Thomas (additional)
  7. Didier Trono (additional)
References 25 Referenced 241
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  3. Greenberg, M. E., Iafrate, A. J. & Skowronski, J. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J. 17, 2777–2789 (1998). (10.1093/emboj/17.10.2777) / EMBO J. by ME Greenberg (1998)
  4. Wan, L. et al. PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization. Cell 94, 205–216 (1998). (10.1016/S0092-8674(00)81420-8) / Cell by L Wan (1998)
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  11. Piguet, V. et al. Mechanism of Nef induced CD4 endocytosis: Nef connects CD4 with the µ chain of adaptor complexes. EMBO J. 17, 2472–2481 (1998). (10.1093/emboj/17.9.2472) / EMBO J. by V Piguet (1998)
  12. Le Gall, S. et al. Nef interacts with the µ subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC-I molecules. Immunity 8, 483–495 (1998). (10.1016/S1074-7613(00)80553-1) / Immunity by S Le Gall (1998)
  13. Greenberg, M. et al. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 16, 6964–6976 (1997). (10.1093/emboj/16.23.6964) / EMBO J. by M Greenberg (1997)
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Dates
Type When
Created 23 years, 1 month ago (July 26, 2002, 4:46 a.m.)
Deposited 2 years, 3 months ago (May 18, 2023, 4:01 p.m.)
Indexed 3 weeks, 6 days ago (Aug. 5, 2025, 8:57 a.m.)
Issued 25 years, 6 months ago (Feb. 9, 2000)
Published 25 years, 6 months ago (Feb. 9, 2000)
Published Online 25 years, 6 months ago (Feb. 9, 2000)
Published Print 25 years, 6 months ago (March 1, 2000)
Funders 0

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@article{Piguet_2000, title={HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes}, volume={2}, ISSN={1476-4679}, url={http://dx.doi.org/10.1038/35004038}, DOI={10.1038/35004038}, number={3}, journal={Nature Cell Biology}, publisher={Springer Science and Business Media LLC}, author={Piguet, Vincent and Wan, Lei and Borel, Christelle and Mangasarian, Aram and Demaurex, Nicolas and Thomas, Gary and Trono, Didier}, year={2000}, month=feb, pages={163–167} }