DOI: 10.1038/35002634. Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding

Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding

10.1038/35002634

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Gajiwala, K. S., Chen, H., Cornille, F., Roques, B. P., Reith, W., Mach, B., & Burley, S. K. (2000). Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding. Nature, 403(6772), 916â921.

Authors 7

Ketan S. Gajiwala (first)
Hua Chen (additional)
Fabrice Cornille (additional)
Bernard P. Roques (additional)
Walter Reith (additional)
Bernard Mach (additional)
Stephen K. Burley (additional)

References 25 Referenced 273

Mach, B., Steimle, V., Martinez-Soria, E. & Reith, W. Regulation of MHC class II genes: lessons from a disease. Annu. Rev. Immunol. 14, 301–331 (1996). (10.1146/annurev.immunol.14.1.301) / Annu. Rev. Immunol. by B Mach (1996)
Iwama, A. et al. Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. Mol. Cell Biol. 19, 3940– 3950 (1999). (10.1128/MCB.19.6.3940) / Mol. Cell Biol. by A Iwama (1999)
Dotzlaw, H., Alkhalaf, M. & Murphy, L. C. Characterization of estrogen receptor variant mRNAs from human breast cancers. Mol. Endocrinol. 6, 773–785 (1992). / Mol. Endocrinol. by H Dotzlaw (1992)
Reith, W. et al. MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain. Genes Dev. 4, 1528–1540 ( 1990). (10.1101/gad.4.9.1528) / Genes Dev. by W Reith (1990)
Cornille, F. et al. DNA binding properties of a chemically synthesized DNA binding domain of hRFX1. Nucleic Acids Res. 26, 2143–2149 (1998). (10.1093/nar/26.9.2143) / Nucleic Acids Res. by F Cornille (1998)
Clark, K. L., Halay, E. D., Lai, E. & Burley, S. K. Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364, 412–420 ( 1993). (10.1038/364412a0) / Nature by KL Clark (1993)
Lai, E., Clark, K. L., Burley, S. & James E. Darnell, J. Hepatocyte nuclear factor 3/fork head or “winged helix” proteins: A family of transcription factors of diverse biological function. Proc. Natl Acad. Sci. USA 90, 10421–10423 (1993). (10.1073/pnas.90.22.10421) / Proc. Natl Acad. Sci. USA by E Lai (1993)
Emery, P. et al. A consensus motif in the RFX DNA binding domain and binding domain mutants with altered specificity. Mol. Cell Biol. 16 , 4486–4494 (1996). (10.1128/MCB.16.8.4486) / Mol. Cell Biol. by P Emery (1996)
Ostapchuk, P., Scheirle, G. & Hearing, P. Binding of nuclear factor EF-C to a functional domain of the hepatitis B virus enhancer region. Mol. Cell Biol. 9, 2787–2797 (1989). (10.1128/MCB.9.7.2787) / Mol. Cell Biol. by P Ostapchuk (1989)
Jin, C., Marsden, I., Chen, X. & Liao, X. Dynamic DNA contacts observed in the NMR structure of winged helix protein–DNA complex. J. Mol. Biol. 289, 683–690 (1999). (10.1006/jmbi.1999.2819) / J. Mol. Biol. by C Jin (1999)
Zheng, N., Fraenkel, E., Pabo, C. O. & Pavletich, N. P. Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev. 13, 666– 674 (1999). (10.1101/gad.13.6.666) / Genes Dev. by N Zheng (1999)
Janin, J. Principles of protein–protein recognition from structure to thermodynamics. Biochimie 77, 497–505 (1995). (10.1016/0300-9084(96)88166-1) / Biochimie by J Janin (1995)
Reith, W. et al. RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins. Mol. Cell Biol. 14, 1230–1244 (1994). (10.1128/MCB.14.2.1230) / Mol. Cell Biol. by W Reith (1994)
Lavery, R. & Sklenar, H. The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic acids. J. Biomol. Struct. Dynamics 6, 63– 91 (1988). (10.1080/07391102.1988.10506483) / J. Biomol. Struct. Dynamics by R Lavery (1988)
Klemm, J. D. & Pabo, C. O. Oct-1 POU domain-DNA interactions: cooperative binding of isolated subdomains and effects of covalent linkage. Genes Dev. 10, 27–36 (1996). (10.1101/gad.10.1.27) / Genes Dev. by JD Klemm (1996)
Ramakrishnan, V., Finch, J., Graziano, V. & Sweet, R. Crystal structure of the globular domain of histone H5 and its implications for nucleosome binding. Nature 362, 219–223 (1993). (10.1038/362219a0) / Nature by V Ramakrishnan (1993)
Thomas, J. O. & Wilson, C. M. Selective radiolabelling and identification of a strong nucleosome binding site on the globular domain of histone H5. EMBO J. 5, 3531–3537 (1986). (10.1002/j.1460-2075.1986.tb04679.x) / EMBO J. by JO Thomas (1986)
Buckle, R. S., Maman, J. D. & Allan, J. Site-directed mutagenesis studies on the binding of the globular domain of linker histone H5 to the nucleosome. J. Mol. Biol. 223, 651–659 (1992). (10.1016/0022-2836(92)90981-O) / J. Mol. Biol. by RS Buckle (1992)
Holm, L. & Sander, C. Families of structurally similar proteins, version 1. 0. J. Mol. Biol. 233, 123–138 (1993). (10.1006/jmbi.1993.1489) / J. Mol. Biol. by L Holm (1993)
Goytisolo, F. A. et al. Identification of two DNA-binding sites on the globular domain of histone H5. EMBO J. 15, 3421– 3429 (1996). (10.1002/j.1460-2075.1996.tb00708.x) / EMBO J. by FA Goytisolo (1996)
Cirillo, L. A. et al. Binding of the winged-helix transcription factor HNF3 to a linker histone site on the nucleosome. EMBO J. 17, 244–254 (1998). (10.1093/emboj/17.1.244) / EMBO J. by LA Cirillo (1998)
Zhou, Y. B., Gerchman, S. E., Ramakrishnan, V., Travers, A. & Muyldermans, S. Position and orientation of the globular domain of linker histone H5 on the nucleosome. Nature 395, 402–405 ( 1998). (10.1038/26521) / Nature by YB Zhou (1998)
Brunger, A. T. et al. Crystallography and NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54, 905–921 ( 1998). (10.1107/S0907444998003254) / Acta Crystallogr. D Biol. Crystallogr. by AT Brunger (1998)
Laskowski, R. J., MacArthur, M. W., Moss, D. S. & Thornton, J. M. PROCHECK: a program to check stereochemical quality of protein structures. J. Appl. Cryst. 26, 283– 290 (1993). (10.1107/S0021889892009944) / J. Appl. Cryst. by RJ Laskowski (1993)
Nicholls, A., Sharp, K. & Honig, B. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins Struct. Funct. Genet. 11, 281–296 (1991). (10.1002/prot.340110407) / Proteins Struct. Funct. Genet. by A Nicholls (1991)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:41 a.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 9:49 p.m.)
Indexed	2 weeks, 2 days ago (Aug. 12, 2025, 6:14 p.m.)
Issued	25 years, 6 months ago (Feb. 1, 2000)
Published	25 years, 6 months ago (Feb. 1, 2000)
Published Print	25 years, 6 months ago (Feb. 1, 2000)

Funders 0

None

BibTeX

@article{Gajiwala_2000, title={Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding}, volume={403}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/35002634}, DOI={10.1038/35002634}, number={6772}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Gajiwala, Ketan S. and Chen, Hua and Cornille, Fabrice and Roques, Bernard P. and Reith, Walter and Mach, Bernard and Burley, Stephen K.}, year={2000}, month=feb, pages={916–921} }

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