DOI: 10.1038/33952. Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3

Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3

10.1038/33952

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Rundlett, S. E., Carmen, A. A., Suka, N., Turner, B. M., & Grunstein, M. (1998). Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3. Nature, 392(6678), 831â835.

Authors 5

Stephen E. Rundlett (first)
Andrew A. Carmen (additional)
Noriyuki Suka (additional)
Bryan M. Turner (additional)
Michael Grunstein (additional)

References 24 Referenced 355

Hassig, C. A. et al. Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell 89, 341–347 (1997). (10.1016/S0092-8674(00)80214-7) / Cell by CA Hassig (1997)
Laherty, C. D. et al. Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 89, 349–356 (1997). (10.1016/S0092-8674(00)80215-9) / Cell by CD Laherty (1997)
Kadosh, D. & Struhl, K. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89, 365–371 (1997). (10.1016/S0092-8674(00)80217-2) / Cell by D Kadosh (1997)
Nagy, L. et al. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase Cell 89, 373–380 (1997). (10.1016/S0092-8674(00)80218-4) / Cell by L Nagy (1997)
Heinzel, T. et al. Acomplex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression. Nature 387, 43–48 (1997). (10.1038/387043a0) / Nature by T Heinzel (1997)
Alland, L. et al. Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression. Nature 387, 49–55 (1997). (10.1038/387049a0) / Nature by L Alland (1997)
Rundlett, S. E. et al. HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription. Proc. Natl Acad. Sci. USA 93, 14503–14508 (1996). (10.1073/pnas.93.25.14503) / Proc. Natl Acad. Sci. USA by SE Rundlett (1996)
Slekar, K. H. & Henry, S. A. SIN3 works through two different promoter elements to regulate INO1 gene expression in yeast. Nucleic Acids Res. 23, 1964–1969 (1995). (10.1093/nar/23.11.1964) / Nucleic Acids Res. by KH Slekar (1995)
Strich, R. et al. UME5 is a key regulator of nitrogen repression and meiotic development. Genes Dev. 8, 796–810 (1994). (10.1101/gad.8.7.796) / Genes Dev. by R Strich (1994)
Hecht, A., Strahl-Bolsinger, S. & Grunstein, M. Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383, 92–96 (1996). (10.1038/383092a0) / Nature by A Hecht (1996)
Kasten, M. M., Dorland, S. & Stillman, D. J. Alarge protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators. Mol. Cell. Biol. 17, 4852–4858 (1997). (10.1128/MCB.17.8.4852) / Mol. Cell. Biol. by MM Kasten (1997)
Zhang, Y. et al. Histone deacetylases and Sap18, a novel polypeptide, are components of a human Sin3 complex. Cell 89, 357–364 (1997). (10.1016/S0092-8674(00)80216-0) / Cell by Y Zhang (1997)
Mitchell, A. P. Control of meiotic gene expression in Saccharomyces cerevisiae. Microbiol. Rev. 58, 56–70 (1964). (10.1128/MMBR.58.1.56-70.1994) / Microbiol. Rev. by AP Mitchell (1964)
Grunstein, M. Histone function in transcription. Annu. Rev. Cell Biol. 6, 643–678 (1990). (10.1146/annurev.cb.06.110190.003235) / Annu. Rev. Cell Biol. by M Grunstein (1990)
Luger, K., Mader, A. W., Richmond, R. K., Sargent, D. F. & Richmond, T. J. Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature 389, 251–260 (1997). (10.1038/38444) / Nature by K Luger (1997)
Dean-Johnson, M. & Henry, S. A. Biosynthesis of inositol in yeast. Primary structure of myo-inositol-1-phosphate synthase (EC5.5.1.4) and functional analysis of its structural gene, the INO1 locus. J. Biol. Chem. 264, 1274–1283 (1989). (10.1016/S0021-9258(19)85082-2) / J. Biol. Chem. by M Dean-Johnson (1989)
Mann, R. K. & Grunstein, M. Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo. EMBO J. 11, 3297–3306 (1992). (10.1002/j.1460-2075.1992.tb05408.x) / EMBO J. by RK Mann (1992)
Guthrie, C. & Fink, G. R. Guide to Yeast Genetics and Molecular Biology (Academic, San Deigo, CA, 1991). / Guide to Yeast Genetics and Molecular Biology by C Guthrie (1991)
Kayne, P. S. et al. Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast. Cell 55, 27–39 (1988). (10.1016/0092-8674(88)90006-2) / Cell by PS Kayne (1988)
Laman, H., Balderes, D. & Shore, D. Disturbance of normal cell cycle progression enhances the establishment of transcriptional silencing in Saccharomyces cerevisiae. Mol. Cell. Biol. 15, 3608–3617 (1995). (10.1128/MCB.15.7.3608) / Mol. Cell. Biol. by H Laman (1995)
Flomerfelt, F. A., Briehl, M. M., Dowd, D. R., Dieken, E. S. & Miesfeld, R. L. Elevated glutathione S-transferase gene expression is an early event during steroid-induced lymphocyte apoptosis. J. Cell. Physiol. 154, 573–581 (1993). (10.1002/jcp.1041540316) / J. Cell. Physiol. by FA Flomerfelt (1993)
Strahl-Bolsinger, S., Hecht, A., Luo, K. & Grunstein, M. SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev. 11, 83–93 (1997). (10.1101/gad.11.1.83) / Genes Dev. by S Strahl-Bolsinger (1997)
Clarke, D. J., O'Neill, L. P. & Turner, B. Selective use of H4 acetylation sites in the yeast Saccharomyces cerevisiae. Biochem. J. 294, 557–561 (1993). (10.1042/bj2940557) / Biochem. J. by DJ Clarke (1993)
Vidal, M., Strich, R., Esposito, R. E. & Gaber, R. F. RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes. Mol. Cell. Biol. 11, 6306–6316 (1991). (10.1128/MCB.11.12.6306) / Mol. Cell. Biol. by M Vidal (1991)

Dates

Type	When
Created	23 years ago (July 26, 2002, 4:37 a.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 10:15 p.m.)
Indexed	2 weeks, 6 days ago (Aug. 5, 2025, 8:35 a.m.)
Issued	27 years, 4 months ago (April 1, 1998)
Published	27 years, 4 months ago (April 1, 1998)
Published Online	27 years, 4 months ago (April 1, 1998)
Published Print	27 years, 4 months ago (April 1, 1998)

Funders 0

None

BibTeX

@article{Rundlett_1998, title={Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3}, volume={392}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/33952}, DOI={10.1038/33952}, number={6678}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Rundlett, Stephen E. and Carmen, Andrew A. and Suka, Noriyuki and Turner, Bryan M. and Grunstein, Michael}, year={1998}, month=apr, pages={831–835} }

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