DOI: 10.1038/33423. Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

10.1038/33423

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Zambrowicz, B. P., Friedrich, G. A., Buxton, E. C., Lilleberg, S. L., Person, C., & Sands, A. T. (1998). Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature, 392(6676), 608â611.

Authors 6

Brian P. Zambrowicz (first)
Glenn A. Friedrich (additional)
Eric C. Buxton (additional)
Stan L. Lilleberg (additional)
Christophe Person (additional)
Arthur T. Sands (additional)

References 20 Referenced 368

Adams, M. D.et al. Complementary DNA sequencing: “Expressed sequence tags” and the Human Genome Project. Science 252, 1651–1656 (1991). (10.1126/science.2047873) / Science by MD Adams (1991)
Plasterk, R. H. Reverse genetics of Caenorhabditis elegans. Bioessays 14, 629–633 (1992). (10.1002/bies.950140911) / Bioessays by RH Plasterk (1992)
Spradling, A. C.et al. Gene disruptions using P transposable elements: an integral component of the Drosophila genome project. Proc. Natl Acad. Sci. USA 92, 10824–10830 (1995). (10.1073/pnas.92.24.10824) / Proc. Natl Acad. Sci. USA by AC Spradling (1995)
Gossler, A. & Zachgo, J. in Gene Targeting: A Practical Approach(ed. Joyner, A. L.) 181–227 (Oxford Univ. Press, New York, (1993). / Gene Targeting: A Practical Approach by A Gossler (1993)
Friedrich, G. & Soriano, P. Insertional mutagenesis by retroviruses and promoter traps in embryonic stem cells. Meth. Enzymol. 225, 681–701 (1993). (10.1016/0076-6879(93)25044-3) / Meth. Enzymol. by G Friedrich (1993)
Chen, Z., Friedrich, G. A. & Soriano, P. Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes Dev. 8, 2293–2301 (1994). (10.1101/gad.8.19.2293) / Genes Dev. by Z Chen (1994)
Zambrowicz, B. P.et al. Disruption of overlapping transcripts in the ROSA βgeo 26 gene trap strain leads to widespread expression of βgalactosidase in mouse embryos and hematopoietic cells. Proc. Natl Acad. Sci. USA 94, 3789–3794 (1997). (10.1073/pnas.94.8.3789) / Proc. Natl Acad. Sci. USA by BP Zambrowicz (1997)
Townley, D. J., Avery, B. J., Rosen, B. & Skarnes, W. C. Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice. Genome Res. 7, 293–298 (1997). (10.1101/gr.7.3.293) / Genome Res. by DJ Townley (1997)
Hicks, G. G.et al. Functional genomics in mice by tagged sequence mutagenesis. Nature Genet. 16, 338–344 (1997). (10.1038/ng0897-338) / Nature Genet. by GG Hicks (1997)
Friedrich, G. & Soriano, P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5, 1513–1523 (1991). (10.1101/gad.5.9.1513) / Genes Dev. by G Friedrich (1991)
Skarnes, W., Moss, J., Hurtley, S. & Beddington, R. Capturing genes encoding membrane and secreted proteins important for mouse development. Proc. Natl Acad. Sci. USA 92, 6592–6596 (1995). (10.1073/pnas.92.14.6592) / Proc. Natl Acad. Sci. USA by W Skarnes (1995)
Altschul, S. F., Gish, W., Miller, W., Meyers, E. W. & Lipman, D. J. Basic local alignment search tool. J. Mol. Biol. 215, 403–410 (1990). (10.1016/S0022-2836(05)80360-2) / J. Mol. Biol. by SF Altschul (1990)
Oeltjen, J. C.et al. Large-scale comparative sequence analysis of the human murine Bruton's tyrosine kinase loci reveals conserved regulatory domains. Genome Res. 7, 315–329 (1997). (10.1101/gr.7.4.315) / Genome Res. by JC Oeltjen (1997)
de Weers, M.et al. The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages. Eur. J. Immunol. 23, 3109–3114 (1993). (10.1002/eji.1830231210) / Eur. J. Immunol. by M de Weers (1993)
Chang, W., Hubbard, C., Friedel, C. & Ruley, E. Enrichment of insertional mutants following retrovirus gene trap selection. Virology 193, 737–747 (1993). (10.1006/viro.1993.1182) / Virology by W Chang (1993)
Withers-Ward, E. S., Kitamura, Y., Barnes, J. P. & Coffin, J. M. Distribution of targets for avian retrovirus DNA integration in vivo. Genes Dev. 8, 1473–1487 (1994). (10.1101/gad.8.12.1473) / Genes Dev. by ES Withers-Ward (1994)
Craigie, R. Hotspots and warm spots: integration specificity of retroelements. Trends Genet. 8, 187–190 (1992). (10.1016/0168-9525(92)90223-Q) / Trends Genet. by R Craigie (1992)
Soriano, P., Friedrich, G. & Lawinger, P. Promoter interaction in retrovirus vectors introduced into fibroblasts and embryonic stem cells. J. Virol. 65, 2314–2319 (1991). (10.1128/JVI.65.5.2314-2319.1991) / J. Virol. by P Soriano (1991)
Zhu, B., Bogue, M. A., Lim, D.-S., Hasty, P. & Roth, D. B. Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86, 379–389 (1996). (10.1016/S0092-8674(00)80111-7) / Cell by B Zhu (1996)
Hasty, P., Rivera-Perez, J., Chang, C. & Bradley, A. Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells. Mol. Cell. Biol. 11, 4509–4517 (1991). (10.1128/MCB.11.9.4509) / Mol. Cell. Biol. by P Hasty (1991)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:37 a.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 9:41 p.m.)
Indexed	1 month, 4 weeks ago (July 2, 2025, 2:45 p.m.)
Issued	27 years, 5 months ago (April 1, 1998)
Published	27 years, 5 months ago (April 1, 1998)
Published Print	27 years, 5 months ago (April 1, 1998)

Funders 0

None

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