DOI: 10.1038/324575a0. Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence

Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence

10.1038/324575a0

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Townsend, A. R. M., Bastin, J., Gould, K., & Brownlee, G. G. (1986). Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence. Nature, 324(6097), 575â577.

Authors 4

A. R. M. Townsend (first)
J. Bastin (additional)
K. Gould (additional)
G. G. Brownlee (additional)

References 20 Referenced 182

Zweerink, H. J., Askonas, B. A., Millican, D., Courtneidge, S. A. & Skehel, J. J. Eur. J. Immun. 7, 630–635 (1977). (10.1002/eji.1830070910) / Eur. J. Immun. by HJ Zweerink (1977)
Townsend, A. R. M., McMichael, A. J., Carter, N. P., Huddleston, J. A. & Brownlee, G. G. Cell 39, 13–25 (1984). (10.1016/0092-8674(84)90187-9) / Cell by ARM Townsend (1984)
Yewdell, J. W., Bennink, J. R., Smith, G. L. & Moss, B. Proc. natn. Acad. Sci. U.S.A. 82, 1785–1789 (1985). (10.1073/pnas.82.6.1785) / Proc. natn. Acad. Sci. U.S.A. by JW Yewdell (1985)
Braciale, T. J., Braciale, V. L., Henkel, T. J., Sambrook, J. & Gething, M. J. J. exp. Med. 159, 341–354 (1984). (10.1084/jem.159.2.341) / J. exp. Med. by TJ Braciale (1984)
Townsend, A. R. M., Gotch, F. M. & Davey, J. Cell 42, 457–467 (1985). (10.1016/0092-8674(85)90103-5) / Cell by ARM Townsend (1985)
Townsend, A. R. M. et al. Cell 44, 959–968 (1986). (10.1016/0092-8674(86)90019-X) / Cell by ARM Townsend (1986)
Gething, M. & Sambrook, J. Nature 300, 598–603 (1982). (10.1038/300598a0) / Nature by M Gething (1982)
Gething, M. & Sambrook, J. in Genetics of Influenza Viruses 169–191 (Springer, New York, 1983). (10.1007/978-3-7091-8706-7_6) / Genetics of Influenza Viruses by M Gething (1983)
Zoller, M. J. & Smith, M. Meth. Enzym. 100, 468–500 (1983). (10.1016/0076-6879(83)00074-9) / Meth. Enzym. by MJ Zoller (1983)
Smith, G. L., Murphy, B. R. & Moss, B. Proc. natn. Acad. Sci. U.S.A. 80, 7155–7159 (1983). (10.1073/pnas.80.23.7155) / Proc. natn. Acad. Sci. U.S.A. by GL Smith (1983)
Bennink, J. R., Yewdell, J. W., Smith, G. L., Moller, C. & Moss, B. Nature 311, 578–579 (1984). (10.1038/311578a0) / Nature by JR Bennink (1984)
Bennink, J. R., Yewdell, J. W., Smith, G. L. & Moss, B. J. Virol. 57, 786–791 (1986). (10.1128/jvi.57.3.786-791.1986) / J. Virol. by JR Bennink (1986)
Winter, G., Fields, S. & Brownlee, G. G. Nature 292, 72–75 (1981). (10.1038/292072a0) / Nature by G Winter (1981)
Sabatini, D., Kreibich, G., Morimoto, T. & Adesnik, M. J. Cell Biol. 92, 1–22 (1982). (10.1083/jcb.92.1.1) / J. Cell Biol. by D Sabatini (1982)
Wabuke-Bunoti, M. A. N., Taku, A., Fan, D., Kent, S. & Webster, R. G. J. Immun. 133, 2194–2201 (1984). (10.4049/jimmunol.133.4.2194) / J. Immun. by MAN Wabuke-Bunoti (1984)
Yamada, A., Young, J. F. & Ennis, F. A. J. exp. Med. 162, 1720–1725 (1985). (10.1084/jem.162.5.1720) / J. exp. Med. by A Yamada (1985)
Streicher, H. Z., Berkower, I. J., Busch, M., Gurd, F. R. N. & Berzofski, J. A. Proc. natn. Acad. Sci. U.S.A. 81, 6831–6835 (1984). (10.1073/pnas.81.21.6831) / Proc. natn. Acad. Sci. U.S.A. by HZ Streicher (1984)
Allen, P. M. & Unanue, E. R. J. Immun. 132, 1077–1079 (1984). (10.4049/jimmunol.132.3.1077) / J. Immun. by PM Allen (1984)
Morrison, L. A., Lukacher, A. E., Braciale, V. L., Fan, D. & Braciale, T. J. J. exp. Med. 163, 903–921 (1986). (10.1084/jem.163.4.903) / J. exp. Med. by LA Morrison (1986)
Townsend, A. R. M. & Skehel, J. J. J. exp. Med. 160, 552–563 (1984). (10.1084/jem.160.2.552) / J. exp. Med. by ARM Townsend (1984)

Dates

Type	When
Created	20 years, 9 months ago (Nov. 18, 2004, 1:03 a.m.)
Deposited	2 years, 3 months ago (May 23, 2023, 1:19 p.m.)
Indexed	2 days, 12 hours ago (Aug. 23, 2025, 9:19 p.m.)
Issued	38 years, 8 months ago (Dec. 11, 1986)
Published	38 years, 8 months ago (Dec. 11, 1986)
Published Print	38 years, 8 months ago (Dec. 11, 1986)

Funders 0

None

BibTeX

@article{Townsend_1986, title={Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence}, volume={324}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/324575a0}, DOI={10.1038/324575a0}, number={6097}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Townsend, A. R. M. and Bastin, J. and Gould, K. and Brownlee, G. G.}, year={1986}, month=dec, pages={575–577} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        24
      ]
    ],
    "date-time": "2025-08-24T01:19:41Z",
    "timestamp": 1755998381152
  },
  "reference-count": 20,
  "publisher": "Springer Science and Business Media LLC",
  "issue": "6097",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1986,
            12,
            11
          ]
        ],
        "date-time": "1986-12-11T00:00:00Z",
        "timestamp": 534643200000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.springernature.com/gp/researchers/text-and-data-mining"
    },
    {
      "start": {
        "date-parts": [
          [
            1986,
            12,
            11
          ]
        ],
        "date-time": "1986-12-11T00:00:00Z",
        "timestamp": 534643200000
      },
      "content-version": "vor",
      "delay-in-days": 0,
      "URL": "https://www.springernature.com/gp/researchers/text-and-data-mining"
    },
    {
      "start": {
        "date-parts": [
          [
            1986,
            12,
            11
          ]
        ],
        "date-time": "1986-12-11T00:00:00Z",
        "timestamp": 534643200000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "https://www.springer.com/tdm"
    },
    {
      "start": {
        "date-parts": [
          [
            1986,
            12,
            11
          ]
        ],
        "date-time": "1986-12-11T00:00:00Z",
        "timestamp": 534643200000
      },
      "content-version": "vor",
      "delay-in-days": 0,
      "URL": "https://www.springer.com/tdm"
    }
  ],
  "content-domain": {
    "domain": [
      "link.springer.com"
    ],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1986,
        12,
        11
      ]
    ]
  },
  "DOI": "10.1038/324575a0",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2004,
        11,
        18
      ]
    ],
    "date-time": "2004-11-18T06:03:59Z",
    "timestamp": 1100757839000
  },
  "page": "575-577",
  "update-policy": "http://dx.doi.org/10.1007/springer_crossmark_policy",
  "source": "Crossref",
  "is-referenced-by-count": 182,
  "title": "Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence",
  "prefix": "10.1038",
  "volume": "324",
  "author": [
    {
      "given": "A. R. M.",
      "family": "Townsend",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "J.",
      "family": "Bastin",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "K.",
      "family": "Gould",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "G. G.",
      "family": "Brownlee",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "297",
  "reference": [
    {
      "key": "BF324575a0_CR1",
      "doi-asserted-by": "publisher",
      "first-page": "630",
      "DOI": "10.1002/eji.1830070910",
      "volume": "7",
      "author": "HJ Zweerink",
      "year": "1977",
      "unstructured": "Zweerink, H. J., Askonas, B. A., Millican, D., Courtneidge, S. A. & Skehel, J. J. Eur. J. Immun. 7, 630\u2013635 (1977).",
      "journal-title": "Eur. J. Immun."
    },
    {
      "key": "BF324575a0_CR2",
      "doi-asserted-by": "publisher",
      "first-page": "13",
      "DOI": "10.1016/0092-8674(84)90187-9",
      "volume": "39",
      "author": "ARM Townsend",
      "year": "1984",
      "unstructured": "Townsend, A. R. M., McMichael, A. J., Carter, N. P., Huddleston, J. A. & Brownlee, G. G. Cell 39, 13\u201325 (1984).",
      "journal-title": "Cell"
    },
    {
      "key": "BF324575a0_CR3",
      "doi-asserted-by": "publisher",
      "first-page": "1785",
      "DOI": "10.1073/pnas.82.6.1785",
      "volume": "82",
      "author": "JW Yewdell",
      "year": "1985",
      "unstructured": "Yewdell, J. W., Bennink, J. R., Smith, G. L. & Moss, B. Proc. natn. Acad. Sci. U.S.A. 82, 1785\u20131789 (1985).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF324575a0_CR4",
      "doi-asserted-by": "publisher",
      "first-page": "341",
      "DOI": "10.1084/jem.159.2.341",
      "volume": "159",
      "author": "TJ Braciale",
      "year": "1984",
      "unstructured": "Braciale, T. J., Braciale, V. L., Henkel, T. J., Sambrook, J. & Gething, M. J. J. exp. Med. 159, 341\u2013354 (1984).",
      "journal-title": "J. exp. Med."
    },
    {
      "key": "BF324575a0_CR5",
      "doi-asserted-by": "publisher",
      "first-page": "457",
      "DOI": "10.1016/0092-8674(85)90103-5",
      "volume": "42",
      "author": "ARM Townsend",
      "year": "1985",
      "unstructured": "Townsend, A. R. M., Gotch, F. M. & Davey, J. Cell 42, 457\u2013467 (1985).",
      "journal-title": "Cell"
    },
    {
      "key": "BF324575a0_CR6",
      "doi-asserted-by": "publisher",
      "first-page": "959",
      "DOI": "10.1016/0092-8674(86)90019-X",
      "volume": "44",
      "author": "ARM Townsend",
      "year": "1986",
      "unstructured": "Townsend, A. R. M. et al. Cell 44, 959\u2013968 (1986).",
      "journal-title": "Cell"
    },
    {
      "key": "BF324575a0_CR7",
      "doi-asserted-by": "publisher",
      "first-page": "598",
      "DOI": "10.1038/300598a0",
      "volume": "300",
      "author": "M Gething",
      "year": "1982",
      "unstructured": "Gething, M. & Sambrook, J. Nature 300, 598\u2013603 (1982).",
      "journal-title": "Nature"
    },
    {
      "key": "BF324575a0_CR8",
      "doi-asserted-by": "publisher",
      "first-page": "169",
      "DOI": "10.1007/978-3-7091-8706-7_6",
      "volume-title": "Genetics of Influenza Viruses",
      "author": "M Gething",
      "year": "1983",
      "unstructured": "Gething, M. & Sambrook, J. in Genetics of Influenza Viruses 169\u2013191 (Springer, New York, 1983)."
    },
    {
      "key": "BF324575a0_CR9",
      "doi-asserted-by": "publisher",
      "first-page": "468",
      "DOI": "10.1016/0076-6879(83)00074-9",
      "volume": "100",
      "author": "MJ Zoller",
      "year": "1983",
      "unstructured": "Zoller, M. J. & Smith, M. Meth. Enzym. 100, 468\u2013500 (1983).",
      "journal-title": "Meth. Enzym."
    },
    {
      "key": "BF324575a0_CR10",
      "doi-asserted-by": "publisher",
      "first-page": "7155",
      "DOI": "10.1073/pnas.80.23.7155",
      "volume": "80",
      "author": "GL Smith",
      "year": "1983",
      "unstructured": "Smith, G. L., Murphy, B. R. & Moss, B. Proc. natn. Acad. Sci. U.S.A. 80, 7155\u20137159 (1983).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF324575a0_CR11",
      "doi-asserted-by": "publisher",
      "first-page": "578",
      "DOI": "10.1038/311578a0",
      "volume": "311",
      "author": "JR Bennink",
      "year": "1984",
      "unstructured": "Bennink, J. R., Yewdell, J. W., Smith, G. L., Moller, C. & Moss, B. Nature 311, 578\u2013579 (1984).",
      "journal-title": "Nature"
    },
    {
      "key": "BF324575a0_CR12",
      "doi-asserted-by": "crossref",
      "first-page": "786",
      "DOI": "10.1128/jvi.57.3.786-791.1986",
      "volume": "57",
      "author": "JR Bennink",
      "year": "1986",
      "unstructured": "Bennink, J. R., Yewdell, J. W., Smith, G. L. & Moss, B. J. Virol. 57, 786\u2013791 (1986).",
      "journal-title": "J. Virol."
    },
    {
      "key": "BF324575a0_CR13",
      "doi-asserted-by": "publisher",
      "first-page": "72",
      "DOI": "10.1038/292072a0",
      "volume": "292",
      "author": "G Winter",
      "year": "1981",
      "unstructured": "Winter, G., Fields, S. & Brownlee, G. G. Nature 292, 72\u201375 (1981).",
      "journal-title": "Nature"
    },
    {
      "key": "BF324575a0_CR14",
      "doi-asserted-by": "publisher",
      "first-page": "1",
      "DOI": "10.1083/jcb.92.1.1",
      "volume": "92",
      "author": "D Sabatini",
      "year": "1982",
      "unstructured": "Sabatini, D., Kreibich, G., Morimoto, T. & Adesnik, M. J. Cell Biol. 92, 1\u201322 (1982).",
      "journal-title": "J. Cell Biol."
    },
    {
      "key": "BF324575a0_CR15",
      "doi-asserted-by": "crossref",
      "first-page": "2194",
      "DOI": "10.4049/jimmunol.133.4.2194",
      "volume": "133",
      "author": "MAN Wabuke-Bunoti",
      "year": "1984",
      "unstructured": "Wabuke-Bunoti, M. A. N., Taku, A., Fan, D., Kent, S. & Webster, R. G. J. Immun. 133, 2194\u20132201 (1984).",
      "journal-title": "J. Immun."
    },
    {
      "key": "BF324575a0_CR16",
      "doi-asserted-by": "publisher",
      "first-page": "1720",
      "DOI": "10.1084/jem.162.5.1720",
      "volume": "162",
      "author": "A Yamada",
      "year": "1985",
      "unstructured": "Yamada, A., Young, J. F. & Ennis, F. A. J. exp. Med. 162, 1720\u20131725 (1985).",
      "journal-title": "J. exp. Med."
    },
    {
      "key": "BF324575a0_CR17",
      "doi-asserted-by": "publisher",
      "first-page": "6831",
      "DOI": "10.1073/pnas.81.21.6831",
      "volume": "81",
      "author": "HZ Streicher",
      "year": "1984",
      "unstructured": "Streicher, H. Z., Berkower, I. J., Busch, M., Gurd, F. R. N. & Berzofski, J. A. Proc. natn. Acad. Sci. U.S.A. 81, 6831\u20136835 (1984).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF324575a0_CR18",
      "doi-asserted-by": "crossref",
      "first-page": "1077",
      "DOI": "10.4049/jimmunol.132.3.1077",
      "volume": "132",
      "author": "PM Allen",
      "year": "1984",
      "unstructured": "Allen, P. M. & Unanue, E. R. J. Immun. 132, 1077\u20131079 (1984).",
      "journal-title": "J. Immun."
    },
    {
      "key": "BF324575a0_CR19",
      "doi-asserted-by": "publisher",
      "first-page": "903",
      "DOI": "10.1084/jem.163.4.903",
      "volume": "163",
      "author": "LA Morrison",
      "year": "1986",
      "unstructured": "Morrison, L. A., Lukacher, A. E., Braciale, V. L., Fan, D. & Braciale, T. J. J. exp. Med. 163, 903\u2013921 (1986).",
      "journal-title": "J. exp. Med."
    },
    {
      "key": "BF324575a0_CR20",
      "doi-asserted-by": "publisher",
      "first-page": "552",
      "DOI": "10.1084/jem.160.2.552",
      "volume": "160",
      "author": "ARM Townsend",
      "year": "1984",
      "unstructured": "Townsend, A. R. M. & Skehel, J. J. J. exp. Med. 160, 552\u2013563 (1984).",
      "journal-title": "J. exp. Med."
    }
  ],
  "container-title": "Nature",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "https://www.nature.com/articles/324575a0",
      "content-type": "text/html",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://www.nature.com/articles/324575a0.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "https://www.nature.com/articles/324575a0.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        5,
        23
      ]
    ],
    "date-time": "2023-05-23T17:19:02Z",
    "timestamp": 1684862342000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://www.nature.com/articles/324575a0"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1986,
        12,
        11
      ]
    ]
  },
  "references-count": 20,
  "journal-issue": {
    "issue": "6097",
    "published-print": {
      "date-parts": [
        [
          1986,
          12,
          11
        ]
      ]
    }
  },
  "alternative-id": [
    "BF324575a0"
  ],
  "URL": "http://dx.doi.org/10.1038/324575a0",
  "relation": {},
  "ISSN": [
    "0028-0836",
    "1476-4687"
  ],
  "subject": [],
  "container-title-short": "Nature",
  "published": {
    "date-parts": [
      [
        1986,
        12,
        11
      ]
    ]
  },
  "assertion": [
    {
      "value": "11 July 1986",
      "order": 1,
      "name": "received",
      "label": "Received",
      "group": {
        "name": "ArticleHistory",
        "label": "Article History"
      }
    },
    {
      "value": "9 October 1986",
      "order": 2,
      "name": "accepted",
      "label": "Accepted",
      "group": {
        "name": "ArticleHistory",
        "label": "Article History"
      }
    },
    {
      "value": "This content has been made available to all.",
      "name": "free",
      "label": "Free to read"
    }
  ]
}