DOI: 10.1038/32419. Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

10.1038/32419

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

de la Pompa, J. L., Timmerman, L. A., Takimoto, H., Yoshida, H., Elia, A. J., Samper, E., Potter, J., Wakeham, A., Marengere, L., Langille, B. L., Crabtree, G. R., & Mak, T. W. (1998). Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum. Nature, 392(6672), 182â186.

Authors 12

José Luis de la Pompa (first)
Luika A. Timmerman (additional)
Hiroaki Takimoto (additional)
Hiroki Yoshida (additional)
Andrew J. Elia (additional)
Enrique Samper (additional)
Julia Potter (additional)
Andrew Wakeham (additional)
Luc Marengere (additional)
B. Lowell Langille (additional)
Gerald R. Crabtree (additional)
Tak W. Mak (additional)

References 24 Referenced 547

Shaw, J. P. et al. Identification of a putative regulator of early T cell activation genes. Science 241, 202–205 (1988). (10.1126/science.3260404) / Science by JP Shaw (1988)
Flanagan, W. M., Corthesy, B., Bram, R. J. & Crabtree, G. R. Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A. Nature 352, 803–807 (1991). (10.1038/352803a0) / Nature by WM Flanagan (1991)
Clipstone, N. A. & Crabtree, G. R. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 357, 695–697 (1992). (10.1038/357695a0) / Nature by NA Clipstone (1992)
Eisenberg, L. M. & Markwald, R. R. Molecular regulation of atrioventricular valvuloseptal morphogenesis. Circ. Res. 77, 1–6 (1995). (10.1161/01.RES.77.1.1) / Circ. Res. by LM Eisenberg (1995)
Liu, J. et al. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66, 807–815 (1991). (10.1016/0092-8674(91)90124-H) / Cell by J Liu (1991)
Beals, C. R., Clipstone, N. A., Ho, S. N. & Crabtree, G. R. Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction. Genes Dev. 11, 824–834 (1997). (10.1101/gad.11.7.824) / Genes Dev. by CR Beals (1997)
Buck, C. A. et al. Cell adhesion receptors and early mammalian heart development: an overview. C. R. Acad. Sci. III 316, 838–859 (1993). / C. R. Acad. Sci. III by CA Buck (1993)
Kirby, M. L., Gale, T. F. & Stewart, D. E. Neural crest cells contribute to normal aorticopulmonary septation. Science 220, 1059–1061 (1983). (10.1126/science.6844926) / Science by ML Kirby (1983)
Runyan, R. B. et al. Signal transduction of a tissue interaction during embryonic heart development. Cell Regul. 1, 301–313 (1990). (10.1091/mbc.1.3.301) / Cell Regul. by RB Runyan (1990)
Gubbay, J. et al. Agene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 346, 245–250 (1990). (10.1038/346245a0) / Nature by J Gubbay (1990)
Schilham, M. W. et al. Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4. Nature 380, 711–714 (1996). (10.1038/380711a0) / Nature by MW Schilham (1996)
Chang, H. Y. et al. Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin. Nature 376, 686–690 (1995). (10.1038/376686a0) / Nature by HY Chang (1995)
Bennett, P. C., Zhao, W., Lawen, A. & Ng, K. T. Cyclosporin A, an inhibitor of calcineurin, impairs memory formation in day-old chicks. Brain Res. 740, 107–117 (1996). (10.1016/0006-8993(96)00441-6) / Brain Res. by PC Bennett (1996)
Jain, J., McCaffrey, P. G., Valge-Archer, V. E. & Rao, A. Nuclear factor of activated T cells contains Fos and Jun. Nature 356, 801–804 (1992). (10.1038/356801a0) / Nature by J Jain (1992)
O'Keefe, S. J., Tamura, J., Kincaid, R. L., Tocci, M. J. & O'Neill, E. A. FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin. Nature 357, 692–694 (1992). (10.1038/357692a0) / Nature by SJ O'Keefe (1992)
Hoey, T., Sun, Y. L., Williamson, K. & Xu, X. Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 2, 461–472 (1995). (10.1016/1074-7613(95)90027-6) / Immunity by T Hoey (1995)
Ho, S. N. et al. NFATc3, a lymphoid-specific NFATc family member that is calcium-regulated and exhibits distinct DNA binding specificity. J. Biol. Chem. 270, 19898–19907 (1995). (10.1074/jbc.270.34.19898) / J. Biol. Chem. by SN Ho (1995)
Hoffman, J. I. Incidence of congenital heart disease: II. prenatal incidence. Pediatr. Cardiol. 16, 155–165 (1995). (10.1007/BF00801907) / Pediatr. Cardiol. by JI Hoffman (1995)
Beals, C. R., Sheridan, C. M., Gardner, P. & Crabtree, G. R. Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 275, 1930–1934 (1997). (10.1126/science.275.5308.1930) / Science by CR Beals (1997)
Northrop, J. P. et al. NF-AT components define a family of transcription factors targeted in T-cell activation. Nature 369, 497–502 (1994). (10.1038/369497a0) / Nature by JP Northrop (1994)
Koop, K. E., MacDonald, L. M. & Lobe, C. G. Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech. Dev. 59, 73–87 (1996). (10.1016/0925-4773(96)00582-5) / Mech. Dev. by KE Koop (1996)
Hui, C. C. & Joyner, A. L. Amouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nature Genet. 3, 241–246 (1993). (10.1038/ng0393-241) / Nature Genet. by CC Hui (1993)
Sassoon, D. A., Garner, I. & Buckingham, M. Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo. Development 104, 155–164 (1988). (10.1242/dev.104.1.155) / Development by DA Sassoon (1988)
Trumpp, A., Blundell, P. A., de la Pompa, J. L. & Zeller, R. The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis. Genes Dev. 6, 14–28 (1992). (10.1101/gad.6.1.14) / Genes Dev. by A Trumpp (1992)

Dates

Type	When
Created	23 years, 1 month ago (July 26, 2002, 4:37 a.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 9:41 p.m.)
Indexed	4 weeks, 2 days ago (Aug. 6, 2025, 9 a.m.)
Issued	27 years, 6 months ago (March 1, 1998)
Published	27 years, 6 months ago (March 1, 1998)
Published Print	27 years, 6 months ago (March 1, 1998)

Funders 0

None

BibTeX

@article{de_la_Pompa_1998, title={Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum}, volume={392}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/32419}, DOI={10.1038/32419}, number={6672}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={de la Pompa, José Luis and Timmerman, Luika A. and Takimoto, Hiroaki and Yoshida, Hiroki and Elia, Andrew J. and Samper, Enrique and Potter, Julia and Wakeham, Andrew and Marengere, Luc and Langille, B. Lowell and Crabtree, Gerald R. and Mak, Tak W.}, year={1998}, month=mar, pages={182–186} }

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    }
  },
  "alternative-id": [
    "BF32419"
  ],
  "URL": "http://dx.doi.org/10.1038/32419",
  "relation": {},
  "ISSN": [
    "0028-0836",
    "1476-4687"
  ],
  "subject": [],
  "container-title-short": "Nature",
  "published": {
    "date-parts": [
      [
        1998,
        3
      ]
    ]
  }
}