Crossref journal-article
Springer Science and Business Media LLC
Nature (297)
Bibliography

Mizushima, N., Noda, T., Yoshimori, T., Tanaka, Y., Ishii, T., George, M. D., Klionsky, D. J., Ohsumi, M., & Ohsumi, Y. (1998). A protein conjugation system essential for autophagy. Nature, 395(6700), 395–398.

Authors 9
  1. Noboru Mizushima (first)
  2. Takeshi Noda (additional)
  3. Tamotsu Yoshimori (additional)
  4. Yae Tanaka (additional)
  5. Tomoko Ishii (additional)
  6. Michael D. George (additional)
  7. Daniel J. Klionsky (additional)
  8. Mariko Ohsumi (additional)
  9. Yoshinori Ohsumi (additional)
References 29 Referenced 1,385
  1. Takeshige, K., Baba, M., Tsuboi, S., Noda, T. & Ohsumi, Y. Autophagy in yeast demonstrated with proteinase-deficient mutants and condtions for its induction. J. Cell Biol. 119, 301–311 (1992). (10.1083/jcb.119.2.301) / J. Cell Biol. by K Takeshige (1992)
  2. Baba, M., Takeshige, K., Baba, N. & Ohsumi, Y. Ultrastructural analysis of the autophagic process in yeast: Detection of autophagosomes and their characterization. J. Cell Biol. 124, 903–913 (1994). (10.1083/jcb.124.6.903) / J. Cell Biol. by M Baba (1994)
  3. Seglen, P. O. & Bohley, P. Autophagy and other vacuolar protein degradation mechanisms. Experientia 48, 158–172 (1992). (10.1007/BF01923509) / Experientia by PO Seglen (1992)
  4. Dunn, W. A. J Autophagy and related mechanisms of lysome-mediated protein degradation. Trends Cell Biol. 4, 139–143 (1994). (10.1016/0962-8924(94)90069-8) / Trends Cell Biol. by WAJ Dunn (1994)
  5. Tsukada, M. & Ohsumi, Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 333, 169–174 (1993). (10.1016/0014-5793(93)80398-E) / FEBS Lett. by M Tsukada (1993)
  6. Kametaka, S., Matsuura, A., Wada, Y. & Ohsumi, Y. Structural and functional analyses of APG5, a gene involved in autophagy in yeast. Gene 178, 139–143 (1996). (10.1016/0378-1119(96)00354-X) / Gene by S Kametaka (1996)
  7. Matsuura, A., Tsukada, M., Wada, Y. & Ohsumi, Y. Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene 192, 245–250 (1997). (10.1016/S0378-1119(97)00084-X) / Gene by A Matsuura (1997)
  8. Funakoshi, T., Matsuura, A., Noda, T. & Ohsumi, Y. Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae. Gene 192, 207–213 (1997). (10.1016/S0378-1119(97)00031-0) / Gene by T Funakoshi (1997)
  9. Kametaka, S., Okano, T., Ohsumi, M. & Ohsumi, Y. Apg14p and Apg6p/Vps30p form a protein complex essential for autophagy in the yeast Saccharomyces cerevisiae. J. Biol. Chem. (in the press).
  10. Noda, T., Matsuura, A., Wada, Y. & Ohsumi, Y. Novel system for monitoring autophagy in the yeast Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun. 210, 126–132 (1995). (10.1006/bbrc.1995.1636) / Biochem. Biophys. Res. Commun. by T Noda (1995)
  11. Klionsky, D. J., Cueva, R. & Yaver, D. S. Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway. J. Cell Biol. 119, 287–299 (1992). (10.1083/jcb.119.2.287) / J. Cell Biol. by DJ Klionsky (1992)
  12. Baba, M., Osumi, M., Scott, S. V., Klionsky, D. J. & Ohsumi, Y. Two distinct pathways for targeting proteins from the cytoplasm to the vacuole/lysome. J. Cell Biol. 139, 1687–1695 (1997). (10.1083/jcb.139.7.1687) / J. Cell Biol. by M Baba (1997)
  13. Scott, S. V. et al. Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole. Proc. Natl Acad. Sci. USA 93, 12304–12308 (1996). (10.1073/pnas.93.22.12304) / Proc. Natl Acad. Sci. USA by SV Scott (1996)
  14. Hochstrasser, M. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30, 405–429 (1996). (10.1146/annurev.genet.30.1.405) / Annu. Rev. Genet. by M Hochstrasser (1996)
  15. Varshavsky, A. The ubiquitin system. Trends Biochem. Sci. 22, 383–387 (1997). (10.1016/S0968-0004(97)01122-5) / Trends Biochem. Sci. by A Varshavsky (1997)
  16. Weissman, A. M. Regulating protein degradation by ubiquitination. Immunol. Today 18, 189–198 (1997). (10.1016/S0167-5699(97)84666-X) / Immunol. Today by AM Weissman (1997)
  17. McGrath, J. P., Jentsch, S. & Varshavsky, A. UBA1: an essential yeast gene encoding ubiquitin-activating enzyme. EMBO J. 10, 227–236 (1991). (10.1002/j.1460-2075.1991.tb07940.x) / EMBO J. by JP McGrath (1991)
  18. Matunis, M. J., Coutavas, E. & Blobel, G. Anovel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J. Cell Biol. 135, 1457–1470 (1996). (10.1083/jcb.135.6.1457) / J. Cell Biol. by MJ Matunis (1996)
  19. Mahajan, R., Delphin, C., Guan, T., Gerace, L. & Melchior, F. Asmall ubiquitin-related polypeptide involved in targeting RasGAP1 to nuclear pore complex protein RanBP2. Cell 88, 97–107 (1997). (10.1016/S0092-8674(00)81862-0) / Cell by R Mahajan (1997)
  20. Mahajan, R., Gerace, L. & Melchior, F. Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association. J. Cell Biol. 140, 259–270 (1998). (10.1083/jcb.140.2.259) / J. Cell Biol. by R Mahajan (1998)
  21. Matunis, M. J., Wu, J. & Blobel, G. SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex. J. Cell Biol. 140, 499–509 (1998). (10.1083/jcb.140.3.499) / J. Cell Biol. by MJ Matunis (1998)
  22. Johnson, E. S., Schwienhorst, I., Dohmen, R. J. & Blobel, G. The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J. 16, 5509–5519 (1997). (10.1093/emboj/16.18.5509) / EMBO J. by ES Johnson (1997)
  23. Liakopoulos, D., Doenges, G., Matuschewski, K. & Jentsch, S. Anovel protein modification pathway related to the ubiquitin system. EMBO J. 17, 2208–2214 (1998). (10.1093/emboj/17.8.2208) / EMBO J. by D Liakopoulos (1998)
  24. Lammer, D. et al. Modification of yeast Cdc53p by the ubiquitin-related protein Rub1p affects function of the SCFCdc4 complex. Genes Dev. 12, 914–926 (1998). (10.1101/gad.12.7.914) / Genes Dev. by D Lammer (1998)
  25. Osaka, F. et al. Anew Nedd8-ligating system for cullin-4A. Genes Dev. (in the press).
  26. Hammond, E. M. et al. Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast. FEBS Lett. 425, 391–395 (1998). (10.1016/S0014-5793(98)00266-X) / FEBS Lett. by EM Hammond (1998)
  27. Noda, T. & Ohsumi, Y. Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast. J. Biol. Chem. 273, 3963–3966 (1998). (10.1074/jbc.273.7.3963) / J. Biol. Chem. by T Noda (1998)
  28. Kamada, Y. et al. Activation of yeast protein kinase C by Rho1 GTPase. J. Biol. Chem. 271, 9193–9196 (1996). (10.1074/jbc.271.16.9193) / J. Biol. Chem. by Y Kamada (1996)
  29. Antebi, A. & Fink, G. R. The yeast Ca2+-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution. Mol. Biol. Cell 3, 633–654 (1992). (10.1091/mbc.3.6.633) / Mol. Biol. Cell by A Antebi (1992)
Dates
Type When
Created 23 years ago (July 26, 2002, 4:39 a.m.)
Deposited 2 years, 3 months ago (May 16, 2023, 8:15 p.m.)
Indexed 22 hours, 12 minutes ago (Aug. 23, 2025, 12:58 a.m.)
Issued 26 years, 11 months ago (Sept. 1, 1998)
Published 26 years, 11 months ago (Sept. 1, 1998)
Published Print 26 years, 11 months ago (Sept. 1, 1998)
Funders 0

None

@article{Mizushima_1998, title={A protein conjugation system essential for autophagy}, volume={395}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/26506}, DOI={10.1038/26506}, number={6700}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Mizushima, Noboru and Noda, Takeshi and Yoshimori, Tamotsu and Tanaka, Yae and Ishii, Tomoko and George, Michael D. and Klionsky, Daniel J. and Ohsumi, Mariko and Ohsumi, Yoshinori}, year={1998}, month=sep, pages={395–398} }