DOI: 10.1038/260500a0. Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene

Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene

10.1038/260500a0

Crossref journal-article

Springer Science and Business Media LLC

Nature (297)

Bibliography

Fiers, W., Contreras, R., Duerinck, F., Haegeman, G., Iserentant, D., Merregaert, J., Min Jou, W., Molemans, F., Raeymaekers, A., Van den Berghe, A., Volckaert, G., & Ysebaert, M. (1976). Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene. Nature, 260(5551), 500â507.

Authors 12

W. Fiers (first)
R. Contreras (additional)
F. Duerinck (additional)
G. Haegeman (additional)
D. Iserentant (additional)
J. Merregaert (additional)
W. Min Jou (additional)
F. Molemans (additional)
A. Raeymaekers (additional)
A. Van den Berghe (additional)
G. Volckaert (additional)
M. Ysebaert (additional)

References 55 Referenced 619

Zinder, N., (ed.) RNA Phage Book, 4, 353–396 (Cold Spring Harbor Laboratory, New York, 1975).
Argetsinger-Steitz, J., J. molec. Biol., 33, 937–945 (1968). (10.1016/0022-2836(68)90329-X) / J. molec. Biol. by J Argetsinger-Steitz (1968)
Weissmann, C., Billeter, M. A., Goodman, H. M., Hindley, J., and Weber, H., A. Rev. Biochem., 42, 303–328 (1973). (10.1146/annurev.bi.42.070173.001511) / A. Rev. Biochem. by C Weissmann (1973)
Fedoroff, N. V., and Zinder, N. D., Proc. natn. Acad. Sci. U.S.A., 68, 1838–1843 (1971). (10.1073/pnas.68.8.1838) / Proc. natn. Acad. Sci. U.S.A. by NV Fedoroff (1971)
Haruna, I., Nozu, K., Ohtaka, Y., and Spiegelman, S., Proc. natn. Acad. Sci. U.S.A., 50, 905–911 (1963). (10.1073/pnas.50.5.905) / Proc. natn. Acad. Sci. U.S.A. by I Haruna (1963)
Weissmann, C., Simon, L., and Ochoa, S., Proc. natn. Acad. Sci. U.S.A., 49, 407–414 (1963). (10.1073/pnas.49.3.407) / Proc. natn. Acad. Sci. U.S.A. by C Weissmann (1963)
Kamen, R., Nature, 228, 527–533 (1970). (10.1038/228527a0) / Nature by R Kamen (1970)
Kondo, M., Gallerani, R., and Weissmann, C., Nature, 228, 525–527 (1970). (10.1038/228525a0) / Nature by M Kondo (1970)
Wahba, A. J., et al., J. biol. Chem., 249, 3314–3316 (1974). (10.1016/S0021-9258(19)42675-6) / J. biol. Chem. by AJ Wahba (1974)
Kozak, M., and Nathans, D., Bact. Rev., 36, 109–134 (1972). (10.1128/br.36.1.109-134.1972) / Bact. Rev. by M Kozak (1972)
Fiers, W., et al., Nature, 256, 273–278 (1975). (10.1038/256273a0) / Nature by W Fiers (1975)
Kolakofsky, D., and Weissmann, C., Nature new Biol., 231, 42–46 (1971). (10.1038/newbio231042a0) / Nature new Biol. by D Kolakofsky (1971)
Fiers, W., et al., Biochimie, 53, 495–506 (1971). (10.1016/S0300-9084(71)80167-0) / Biochimie by W Fiers (1971)
Min Jou, W., Haegeman, G., Ysebaert, M., and Fiers, W., Nature, 237, 82–88 (1972). (10.1038/237082a0) / Nature by W Min Jou (1972)
De Wachter, R., Merregaert, J., Vandenberghe, A., Contreras, R., and Fiers, W., Eur. J. Biochem., 22, 400–414 (1971). (10.1111/j.1432-1033.1971.tb01558.x) / Eur. J. Biochem. by R De Wachter (1971)
Fiers, W., in RNA Phage Book (edit. by Zinder, N.), 353–396 (Cold Spring Harbor Laboratory, New York, 1975). / RNA Phage Book by W Fiers (1975)
Nichols, J. L., Nature, 225, 147–151 (1970). (10.1038/225147a0) / Nature by JL Nichols (1970)
Vandenberghe, A., Min Jou, W., and Fiers, W., Proc. natn. Acad. Sci. U.S.A., 72, 2559–2562 (1975). (10.1073/pnas.72.7.2559) / Proc. natn. Acad. Sci. U.S.A. by A Vandenberghe (1975)
Contreras, R., Vandenberghe, A., Volckaert, G., Min Jou, W., and Fiers, W., FEBS Lett., 24, 339–342 (1972). (10.1016/0014-5793(72)80386-7) / FEBS Lett. by R Contreras (1972)
Rensing, U. F. E., Coulson, A., and Thompson, E. O. P., Biochem. J., 131, 605–610 (1973). (10.1042/bj1310605) / Biochem. J. by UFE Rensing (1973)
De Wachter, R., and Fiers, W., Analyt. Biochem., 49, 184–197 (1972). (10.1016/0003-2697(72)90257-6) / Analyt. Biochem. by R De Wachter (1972)
Sanger, F., Brownlee, G. G., and Barrell, B. G., J. molec. Biol., 13, 373–398 (1965). (10.1016/S0022-2836(65)80104-8) / J. molec. Biol. by F Sanger (1965)
Brownlee, G. G., Determination of Sequences in RNA (edit. by Work, T. S., and Work, E.) (North-Holland, Amsterdam, 1972). (10.1016/S0075-7535(08)70528-X) / Determination of Sequences in RNA by GG Brownlee (1972)
Haegeman, G., and Fiers, W., Eur. J. Biochem., 36, 135–143 (1973). (10.1111/j.1432-1033.1973.tb02893.x) / Eur. J. Biochem. by G Haegeman (1973)
Volckaert, G., and Fiers, W., Analyt. Biochem., 62, 573–583 (1974). (10.1016/0003-2697(74)90190-0) / Analyt. Biochem. by G Volckaert (1974)
Contreras, R., and Fiers, W., Analyt. Biochem., 67, 319–326 (1975). (10.1016/0003-2697(75)90299-7) / Analyt. Biochem. by R Contreras (1975)
Contreras, R., and Fiers, W., FEBS Lett., 16, 281–283 (1971). (10.1016/0014-5793(71)80370-8) / FEBS Lett. by R Contreras (1971)
Volckaert, G., Min Jou, W., and Fiers, W., Analyt. Biochem. (in the press).
Tinoco, I., Jr, et al., Nature new biol., 246, 40–41 (1973). (10.1038/newbio246040a0) / Nature new biol. by I Tinoco Jr (1973)
Borer, P. N., Dengler, B., and Tinoco, I., Jr, J. molec. Biol., 86, 843–853 (1974). (10.1016/0022-2836(74)90357-X) / J. molec. Biol. by PN Borer (1974)
Boedtker, H., Biochemistry, 6, 2718–2727 (1967). (10.1021/bi00861a011) / Biochemistry by H Boedtker (1967)
Siegers, H., Clauwaert, J., and Fiers, W., Biopolymers, 12, 2033–2044 (1973). (10.1002/bip.1973.360120910) / Biopolymers by H Siegers (1973)
Gralla, J., Steitz, J. A., and Crothers, D. M., Nature, 248, 204–208 (1974). (10.1038/248204a0) / Nature by J Gralla (1974)
Klug, A., Ladner, J., and Robertus, J. D., J. molec. Biol., 89, 511–516 (1974). (10.1016/0022-2836(74)90480-X) / J. molec. Biol. by A Klug (1974)
Lodish, H. F., Nature, 220, 345–349 (1968). (10.1038/220345a0) / Nature by HF Lodish (1968)
Osborn, M., Weber, K., and Lodish, H. F., Biochem. biophys. Res. Commun., 41, 748–756 (1970). (10.1016/0006-291X(70)90077-X) / Biochem. biophys. Res. Commun. by M Osborn (1970)
Argetsinger-Steitz, J., Nature, 224, 957–964 (1969). (10.1038/224957a0) / Nature by J Argetsinger-Steitz (1969)
Shine, J., and Dalgarno, L., Nature, 254, 34–38 (1975). (10.1038/254034a0) / Nature by J Shine (1975)
Argetsinger-Steitz, J., and Jakes, K., Proc. natn. Acad. Sci. U.S.A., 72, 4734–4738 (1975). (10.1073/pnas.72.12.4734) / Proc. natn. Acad. Sci. U.S.A. by J Argetsinger-Steitz (1975)
Lodish, H. F., J. molec. Biol., 50, 689–702 (1970). (10.1016/0022-2836(70)90093-8) / J. molec. Biol. by HF Lodish (1970)
Argetsinger-Steitz, J., J. molec. Biol., 73, 1–16 (1973). (10.1016/0022-2836(73)90155-1) / J. molec. Biol. by J Argetsinger-Steitz (1973)
Bernardi, A., and Spahr, P. F., Proc. natn. Acad. Sci. U.S.A., 69, 3033–3037 (1972). (10.1073/pnas.69.10.3033) / Proc. natn. Acad. Sci. U.S.A. by A Bernardi (1972)
Atkins, J. F., and Gesteland, R. F., Molec. gen. Genet., 139, 19–31 (1975). (10.1007/BF00267992) / Molec. gen. Genet. by JF Atkins (1975)
Senear, A. W., and Argetsinger-Steitz, J., J. biol. Chem. (in the press).
Fedoroff, N. V., and Zinder, N. D., Nature new Biol., 241, 105–108 (1973). (10.1038/newbio241105a0) / Nature new Biol. by NV Fedoroff (1973)
Carmichael, G. G., Weber, K., Niveleau, A., and Wahba, A. J., J. biol. Chem., 250, 3607–3612 (1975). (10.1016/S0021-9258(19)41440-3) / J. biol. Chem. by GG Carmichael (1975)
Min Jou, W., Haegeman, G., and Fiers, W., FEBS Lett., 13, 105–109 (1971). (10.1016/0014-5793(71)80210-7) / FEBS Lett. by W Min Jou (1971)
Adams, J. M., Jeppesen, P. G. N., Sanger, F., and Barrell, B. G., Nature, 223, 1009–1014 (1969). (10.1038/2231009a0) / Nature by JM Adams (1969)
Fitch, W. M., J. molec. Biol., 3, 279–291 (1974). / J. molec. Biol. by WM Fitch (1974)
Gralla, J., and Delisi, C., Nature, 248, 330–332 (1974). (10.1038/248330a0) / Nature by J Gralla (1974)
Ricard, B., and Salser, W., Biochem. biophys. Res. Commun., 63, 548–554 (1975). (10.1016/S0006-291X(75)80419-0) / Biochem. biophys. Res. Commun. by B Ricard (1975)
Air, G. M., Blackburn, E. H., Sanger, F., and Coulson, A. R., J. molec. Biol., 96, 703–719 (1975). (10.1016/0022-2836(75)90147-3) / J. molec. Biol. by GM Air (1975)
Harada, F., and Nishimura, S., Biochemistry, 13, 300–307 (1974). (10.1021/bi00699a011) / Biochemistry by F Harada (1974)
Fiers, W., et al., Abstr. 3rd int. Cong. Virol., Madrid, 17 (1975).
Weiner, A. M., and Weber, K., Nature new Biol., 234, 206–209 (1971). (10.1038/newbio234206a0) / Nature new Biol. by AM Weiner (1971)

Dates

Type	When
Created	20 years ago (Aug. 3, 2005, 1:18 p.m.)
Deposited	2 years, 3 months ago (May 16, 2023, 8:36 p.m.)
Indexed	33 minutes ago (Aug. 30, 2025, 3:07 a.m.)
Issued	49 years, 4 months ago (April 8, 1976)
Published	49 years, 4 months ago (April 8, 1976)
Published Print	49 years, 4 months ago (April 8, 1976)

Funders 0

None

BibTeX

@article{Fiers_1976, title={Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene}, volume={260}, ISSN={1476-4687}, url={http://dx.doi.org/10.1038/260500a0}, DOI={10.1038/260500a0}, number={5551}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Fiers, W. and Contreras, R. and Duerinck, F. and Haegeman, G. and Iserentant, D. and Merregaert, J. and Min Jou, W. and Molemans, F. and Raeymaekers, A. and Van den Berghe, A. and Volckaert, G. and Ysebaert, M.}, year={1976}, month=apr, pages={500–507} }

JSON

{
  "indexed": {
    "date-parts": [
      [
        2025,
        8,
        30
      ]
    ],
    "date-time": "2025-08-30T07:07:52Z",
    "timestamp": 1756537672799
  },
  "reference-count": 55,
  "publisher": "Springer Science and Business Media LLC",
  "issue": "5551",
  "license": [
    {
      "start": {
        "date-parts": [
          [
            1976,
            4,
            8
          ]
        ],
        "date-time": "1976-04-08T00:00:00Z",
        "timestamp": 197769600000
      },
      "content-version": "tdm",
      "delay-in-days": 0,
      "URL": "http://www.springer.com/tdm"
    },
    {
      "start": {
        "date-parts": [
          [
            1976,
            4,
            8
          ]
        ],
        "date-time": "1976-04-08T00:00:00Z",
        "timestamp": 197769600000
      },
      "content-version": "vor",
      "delay-in-days": 0,
      "URL": "http://www.springer.com/tdm"
    }
  ],
  "content-domain": {
    "domain": [],
    "crossmark-restriction": false
  },
  "published-print": {
    "date-parts": [
      [
        1976,
        4,
        8
      ]
    ]
  },
  "DOI": "10.1038/260500a0",
  "type": "journal-article",
  "created": {
    "date-parts": [
      [
        2005,
        8,
        3
      ]
    ],
    "date-time": "2005-08-03T17:18:51Z",
    "timestamp": 1123089531000
  },
  "page": "500-507",
  "source": "Crossref",
  "is-referenced-by-count": 619,
  "title": "Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene",
  "prefix": "10.1038",
  "volume": "260",
  "author": [
    {
      "given": "W.",
      "family": "Fiers",
      "sequence": "first",
      "affiliation": []
    },
    {
      "given": "R.",
      "family": "Contreras",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "F.",
      "family": "Duerinck",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "G.",
      "family": "Haegeman",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "D.",
      "family": "Iserentant",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "J.",
      "family": "Merregaert",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "W.",
      "family": "Min Jou",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "F.",
      "family": "Molemans",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "A.",
      "family": "Raeymaekers",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "A.",
      "family": "Van den Berghe",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "G.",
      "family": "Volckaert",
      "sequence": "additional",
      "affiliation": []
    },
    {
      "given": "M.",
      "family": "Ysebaert",
      "sequence": "additional",
      "affiliation": []
    }
  ],
  "member": "297",
  "reference": [
    {
      "key": "BF260500a0_CR1",
      "unstructured": "Zinder, N., (ed.) RNA Phage Book, 4, 353\u2013396 (Cold Spring Harbor Laboratory, New York, 1975)."
    },
    {
      "key": "BF260500a0_CR2",
      "doi-asserted-by": "publisher",
      "first-page": "937",
      "DOI": "10.1016/0022-2836(68)90329-X",
      "volume": "33",
      "author": "J Argetsinger-Steitz",
      "year": "1968",
      "unstructured": "Argetsinger-Steitz, J., J. molec. Biol., 33, 937\u2013945 (1968).",
      "journal-title": "J. molec. Biol."
    },
    {
      "key": "BF260500a0_CR3",
      "doi-asserted-by": "publisher",
      "first-page": "303",
      "DOI": "10.1146/annurev.bi.42.070173.001511",
      "volume": "42",
      "author": "C Weissmann",
      "year": "1973",
      "unstructured": "Weissmann, C., Billeter, M. A., Goodman, H. M., Hindley, J., and Weber, H., A. Rev. Biochem., 42, 303\u2013328 (1973).",
      "journal-title": "A. Rev. Biochem."
    },
    {
      "key": "BF260500a0_CR4",
      "doi-asserted-by": "publisher",
      "first-page": "1838",
      "DOI": "10.1073/pnas.68.8.1838",
      "volume": "68",
      "author": "NV Fedoroff",
      "year": "1971",
      "unstructured": "Fedoroff, N. V., and Zinder, N. D., Proc. natn. Acad. Sci. U.S.A., 68, 1838\u20131843 (1971).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF260500a0_CR5",
      "doi-asserted-by": "publisher",
      "first-page": "905",
      "DOI": "10.1073/pnas.50.5.905",
      "volume": "50",
      "author": "I Haruna",
      "year": "1963",
      "unstructured": "Haruna, I., Nozu, K., Ohtaka, Y., and Spiegelman, S., Proc. natn. Acad. Sci. U.S.A., 50, 905\u2013911 (1963).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF260500a0_CR6",
      "doi-asserted-by": "publisher",
      "first-page": "407",
      "DOI": "10.1073/pnas.49.3.407",
      "volume": "49",
      "author": "C Weissmann",
      "year": "1963",
      "unstructured": "Weissmann, C., Simon, L., and Ochoa, S., Proc. natn. Acad. Sci. U.S.A., 49, 407\u2013414 (1963).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF260500a0_CR7",
      "doi-asserted-by": "publisher",
      "first-page": "527",
      "DOI": "10.1038/228527a0",
      "volume": "228",
      "author": "R Kamen",
      "year": "1970",
      "unstructured": "Kamen, R., Nature, 228, 527\u2013533 (1970).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR8",
      "doi-asserted-by": "publisher",
      "first-page": "525",
      "DOI": "10.1038/228525a0",
      "volume": "228",
      "author": "M Kondo",
      "year": "1970",
      "unstructured": "Kondo, M., Gallerani, R., and Weissmann, C., Nature, 228, 525\u2013527 (1970).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR9",
      "doi-asserted-by": "crossref",
      "first-page": "3314",
      "DOI": "10.1016/S0021-9258(19)42675-6",
      "volume": "249",
      "author": "AJ Wahba",
      "year": "1974",
      "unstructured": "Wahba, A. J., et al., J. biol. Chem., 249, 3314\u20133316 (1974).",
      "journal-title": "J. biol. Chem."
    },
    {
      "key": "BF260500a0_CR10",
      "doi-asserted-by": "crossref",
      "first-page": "109",
      "DOI": "10.1128/br.36.1.109-134.1972",
      "volume": "36",
      "author": "M Kozak",
      "year": "1972",
      "unstructured": "Kozak, M., and Nathans, D., Bact. Rev., 36, 109\u2013134 (1972).",
      "journal-title": "Bact. Rev."
    },
    {
      "key": "BF260500a0_CR11",
      "doi-asserted-by": "publisher",
      "first-page": "273",
      "DOI": "10.1038/256273a0",
      "volume": "256",
      "author": "W Fiers",
      "year": "1975",
      "unstructured": "Fiers, W., et al., Nature, 256, 273\u2013278 (1975).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR12",
      "doi-asserted-by": "publisher",
      "first-page": "42",
      "DOI": "10.1038/newbio231042a0",
      "volume": "231",
      "author": "D Kolakofsky",
      "year": "1971",
      "unstructured": "Kolakofsky, D., and Weissmann, C., Nature new Biol., 231, 42\u201346 (1971).",
      "journal-title": "Nature new Biol."
    },
    {
      "key": "BF260500a0_CR13",
      "doi-asserted-by": "publisher",
      "first-page": "495",
      "DOI": "10.1016/S0300-9084(71)80167-0",
      "volume": "53",
      "author": "W Fiers",
      "year": "1971",
      "unstructured": "Fiers, W., et al., Biochimie, 53, 495\u2013506 (1971).",
      "journal-title": "Biochimie"
    },
    {
      "key": "BF260500a0_CR14",
      "doi-asserted-by": "publisher",
      "first-page": "82",
      "DOI": "10.1038/237082a0",
      "volume": "237",
      "author": "W Min Jou",
      "year": "1972",
      "unstructured": "Min Jou, W., Haegeman, G., Ysebaert, M., and Fiers, W., Nature, 237, 82\u201388 (1972).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR15",
      "doi-asserted-by": "publisher",
      "first-page": "400",
      "DOI": "10.1111/j.1432-1033.1971.tb01558.x",
      "volume": "22",
      "author": "R De Wachter",
      "year": "1971",
      "unstructured": "De Wachter, R., Merregaert, J., Vandenberghe, A., Contreras, R., and Fiers, W., Eur. J. Biochem., 22, 400\u2013414 (1971).",
      "journal-title": "Eur. J. Biochem."
    },
    {
      "key": "BF260500a0_CR16",
      "first-page": "353",
      "volume-title": "RNA Phage Book",
      "author": "W Fiers",
      "year": "1975",
      "unstructured": "Fiers, W., in RNA Phage Book (edit. by Zinder, N.), 353\u2013396 (Cold Spring Harbor Laboratory, New York, 1975)."
    },
    {
      "key": "BF260500a0_CR17",
      "doi-asserted-by": "publisher",
      "first-page": "147",
      "DOI": "10.1038/225147a0",
      "volume": "225",
      "author": "JL Nichols",
      "year": "1970",
      "unstructured": "Nichols, J. L., Nature, 225, 147\u2013151 (1970).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR18",
      "doi-asserted-by": "publisher",
      "first-page": "2559",
      "DOI": "10.1073/pnas.72.7.2559",
      "volume": "72",
      "author": "A Vandenberghe",
      "year": "1975",
      "unstructured": "Vandenberghe, A., Min Jou, W., and Fiers, W., Proc. natn. Acad. Sci. U.S.A., 72, 2559\u20132562 (1975).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF260500a0_CR19",
      "doi-asserted-by": "publisher",
      "first-page": "339",
      "DOI": "10.1016/0014-5793(72)80386-7",
      "volume": "24",
      "author": "R Contreras",
      "year": "1972",
      "unstructured": "Contreras, R., Vandenberghe, A., Volckaert, G., Min Jou, W., and Fiers, W., FEBS Lett., 24, 339\u2013342 (1972).",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "BF260500a0_CR20",
      "doi-asserted-by": "publisher",
      "first-page": "605",
      "DOI": "10.1042/bj1310605",
      "volume": "131",
      "author": "UFE Rensing",
      "year": "1973",
      "unstructured": "Rensing, U. F. E., Coulson, A., and Thompson, E. O. P., Biochem. J., 131, 605\u2013610 (1973).",
      "journal-title": "Biochem. J."
    },
    {
      "key": "BF260500a0_CR21",
      "doi-asserted-by": "publisher",
      "first-page": "184",
      "DOI": "10.1016/0003-2697(72)90257-6",
      "volume": "49",
      "author": "R De Wachter",
      "year": "1972",
      "unstructured": "De Wachter, R., and Fiers, W., Analyt. Biochem., 49, 184\u2013197 (1972).",
      "journal-title": "Analyt. Biochem."
    },
    {
      "key": "BF260500a0_CR22",
      "doi-asserted-by": "publisher",
      "first-page": "373",
      "DOI": "10.1016/S0022-2836(65)80104-8",
      "volume": "13",
      "author": "F Sanger",
      "year": "1965",
      "unstructured": "Sanger, F., Brownlee, G. G., and Barrell, B. G., J. molec. Biol., 13, 373\u2013398 (1965).",
      "journal-title": "J. molec. Biol."
    },
    {
      "key": "BF260500a0_CR23",
      "doi-asserted-by": "publisher",
      "DOI": "10.1016/S0075-7535(08)70528-X",
      "volume-title": "Determination of Sequences in RNA",
      "author": "GG Brownlee",
      "year": "1972",
      "unstructured": "Brownlee, G. G., Determination of Sequences in RNA (edit. by Work, T. S., and Work, E.) (North-Holland, Amsterdam, 1972)."
    },
    {
      "key": "BF260500a0_CR24",
      "doi-asserted-by": "publisher",
      "first-page": "135",
      "DOI": "10.1111/j.1432-1033.1973.tb02893.x",
      "volume": "36",
      "author": "G Haegeman",
      "year": "1973",
      "unstructured": "Haegeman, G., and Fiers, W., Eur. J. Biochem., 36, 135\u2013143 (1973).",
      "journal-title": "Eur. J. Biochem."
    },
    {
      "key": "BF260500a0_CR25",
      "doi-asserted-by": "publisher",
      "first-page": "573",
      "DOI": "10.1016/0003-2697(74)90190-0",
      "volume": "62",
      "author": "G Volckaert",
      "year": "1974",
      "unstructured": "Volckaert, G., and Fiers, W., Analyt. Biochem., 62, 573\u2013583 (1974).",
      "journal-title": "Analyt. Biochem."
    },
    {
      "key": "BF260500a0_CR26",
      "doi-asserted-by": "publisher",
      "first-page": "319",
      "DOI": "10.1016/0003-2697(75)90299-7",
      "volume": "67",
      "author": "R Contreras",
      "year": "1975",
      "unstructured": "Contreras, R., and Fiers, W., Analyt. Biochem., 67, 319\u2013326 (1975).",
      "journal-title": "Analyt. Biochem."
    },
    {
      "key": "BF260500a0_CR27",
      "doi-asserted-by": "publisher",
      "first-page": "281",
      "DOI": "10.1016/0014-5793(71)80370-8",
      "volume": "16",
      "author": "R Contreras",
      "year": "1971",
      "unstructured": "Contreras, R., and Fiers, W., FEBS Lett., 16, 281\u2013283 (1971).",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "BF260500a0_CR28",
      "unstructured": "Volckaert, G., Min Jou, W., and Fiers, W., Analyt. Biochem. (in the press)."
    },
    {
      "key": "BF260500a0_CR29",
      "doi-asserted-by": "publisher",
      "first-page": "40",
      "DOI": "10.1038/newbio246040a0",
      "volume": "246",
      "author": "I Tinoco Jr",
      "year": "1973",
      "unstructured": "Tinoco, I., Jr, et al., Nature new biol., 246, 40\u201341 (1973).",
      "journal-title": "Nature new biol."
    },
    {
      "key": "BF260500a0_CR30",
      "doi-asserted-by": "publisher",
      "first-page": "843",
      "DOI": "10.1016/0022-2836(74)90357-X",
      "volume": "86",
      "author": "PN Borer",
      "year": "1974",
      "unstructured": "Borer, P. N., Dengler, B., and Tinoco, I., Jr, J. molec. Biol., 86, 843\u2013853 (1974).",
      "journal-title": "J. molec. Biol."
    },
    {
      "key": "BF260500a0_CR31",
      "doi-asserted-by": "publisher",
      "first-page": "2718",
      "DOI": "10.1021/bi00861a011",
      "volume": "6",
      "author": "H Boedtker",
      "year": "1967",
      "unstructured": "Boedtker, H., Biochemistry, 6, 2718\u20132727 (1967).",
      "journal-title": "Biochemistry"
    },
    {
      "key": "BF260500a0_CR32",
      "doi-asserted-by": "publisher",
      "first-page": "2033",
      "DOI": "10.1002/bip.1973.360120910",
      "volume": "12",
      "author": "H Siegers",
      "year": "1973",
      "unstructured": "Siegers, H., Clauwaert, J., and Fiers, W., Biopolymers, 12, 2033\u20132044 (1973).",
      "journal-title": "Biopolymers"
    },
    {
      "key": "BF260500a0_CR33",
      "doi-asserted-by": "publisher",
      "first-page": "204",
      "DOI": "10.1038/248204a0",
      "volume": "248",
      "author": "J Gralla",
      "year": "1974",
      "unstructured": "Gralla, J., Steitz, J. A., and Crothers, D. M., Nature, 248, 204\u2013208 (1974).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR34",
      "doi-asserted-by": "publisher",
      "first-page": "511",
      "DOI": "10.1016/0022-2836(74)90480-X",
      "volume": "89",
      "author": "A Klug",
      "year": "1974",
      "unstructured": "Klug, A., Ladner, J., and Robertus, J. D., J. molec. Biol., 89, 511\u2013516 (1974).",
      "journal-title": "J. molec. Biol."
    },
    {
      "key": "BF260500a0_CR35",
      "doi-asserted-by": "publisher",
      "first-page": "345",
      "DOI": "10.1038/220345a0",
      "volume": "220",
      "author": "HF Lodish",
      "year": "1968",
      "unstructured": "Lodish, H. F., Nature, 220, 345\u2013349 (1968).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR36",
      "doi-asserted-by": "publisher",
      "first-page": "748",
      "DOI": "10.1016/0006-291X(70)90077-X",
      "volume": "41",
      "author": "M Osborn",
      "year": "1970",
      "unstructured": "Osborn, M., Weber, K., and Lodish, H. F., Biochem. biophys. Res. Commun., 41, 748\u2013756 (1970).",
      "journal-title": "Biochem. biophys. Res. Commun."
    },
    {
      "key": "BF260500a0_CR37",
      "doi-asserted-by": "publisher",
      "first-page": "957",
      "DOI": "10.1038/224957a0",
      "volume": "224",
      "author": "J Argetsinger-Steitz",
      "year": "1969",
      "unstructured": "Argetsinger-Steitz, J., Nature, 224, 957\u2013964 (1969).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR38",
      "doi-asserted-by": "publisher",
      "first-page": "34",
      "DOI": "10.1038/254034a0",
      "volume": "254",
      "author": "J Shine",
      "year": "1975",
      "unstructured": "Shine, J., and Dalgarno, L., Nature, 254, 34\u201338 (1975).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR39",
      "doi-asserted-by": "publisher",
      "first-page": "4734",
      "DOI": "10.1073/pnas.72.12.4734",
      "volume": "72",
      "author": "J Argetsinger-Steitz",
      "year": "1975",
      "unstructured": "Argetsinger-Steitz, J., and Jakes, K., Proc. natn. Acad. Sci. U.S.A., 72, 4734\u20134738 (1975).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF260500a0_CR40",
      "doi-asserted-by": "publisher",
      "first-page": "689",
      "DOI": "10.1016/0022-2836(70)90093-8",
      "volume": "50",
      "author": "HF Lodish",
      "year": "1970",
      "unstructured": "Lodish, H. F., J. molec. Biol., 50, 689\u2013702 (1970).",
      "journal-title": "J. molec. Biol."
    },
    {
      "key": "BF260500a0_CR41",
      "doi-asserted-by": "publisher",
      "first-page": "1",
      "DOI": "10.1016/0022-2836(73)90155-1",
      "volume": "73",
      "author": "J Argetsinger-Steitz",
      "year": "1973",
      "unstructured": "Argetsinger-Steitz, J., J. molec. Biol., 73, 1\u201316 (1973).",
      "journal-title": "J. molec. Biol."
    },
    {
      "key": "BF260500a0_CR42",
      "doi-asserted-by": "publisher",
      "first-page": "3033",
      "DOI": "10.1073/pnas.69.10.3033",
      "volume": "69",
      "author": "A Bernardi",
      "year": "1972",
      "unstructured": "Bernardi, A., and Spahr, P. F., Proc. natn. Acad. Sci. U.S.A., 69, 3033\u20133037 (1972).",
      "journal-title": "Proc. natn. Acad. Sci. U.S.A."
    },
    {
      "key": "BF260500a0_CR43",
      "doi-asserted-by": "publisher",
      "first-page": "19",
      "DOI": "10.1007/BF00267992",
      "volume": "139",
      "author": "JF Atkins",
      "year": "1975",
      "unstructured": "Atkins, J. F., and Gesteland, R. F., Molec. gen. Genet., 139, 19\u201331 (1975).",
      "journal-title": "Molec. gen. Genet."
    },
    {
      "key": "BF260500a0_CR44",
      "unstructured": "Senear, A. W., and Argetsinger-Steitz, J., J. biol. Chem. (in the press)."
    },
    {
      "key": "BF260500a0_CR45",
      "doi-asserted-by": "publisher",
      "first-page": "105",
      "DOI": "10.1038/newbio241105a0",
      "volume": "241",
      "author": "NV Fedoroff",
      "year": "1973",
      "unstructured": "Fedoroff, N. V., and Zinder, N. D., Nature new Biol., 241, 105\u2013108 (1973).",
      "journal-title": "Nature new Biol."
    },
    {
      "key": "BF260500a0_CR46",
      "doi-asserted-by": "crossref",
      "first-page": "3607",
      "DOI": "10.1016/S0021-9258(19)41440-3",
      "volume": "250",
      "author": "GG Carmichael",
      "year": "1975",
      "unstructured": "Carmichael, G. G., Weber, K., Niveleau, A., and Wahba, A. J., J. biol. Chem., 250, 3607\u20133612 (1975).",
      "journal-title": "J. biol. Chem."
    },
    {
      "key": "BF260500a0_CR47",
      "doi-asserted-by": "publisher",
      "first-page": "105",
      "DOI": "10.1016/0014-5793(71)80210-7",
      "volume": "13",
      "author": "W Min Jou",
      "year": "1971",
      "unstructured": "Min Jou, W., Haegeman, G., and Fiers, W., FEBS Lett., 13, 105\u2013109 (1971).",
      "journal-title": "FEBS Lett."
    },
    {
      "key": "BF260500a0_CR48",
      "doi-asserted-by": "publisher",
      "first-page": "1009",
      "DOI": "10.1038/2231009a0",
      "volume": "223",
      "author": "JM Adams",
      "year": "1969",
      "unstructured": "Adams, J. M., Jeppesen, P. G. N., Sanger, F., and Barrell, B. G., Nature, 223, 1009\u20131014 (1969).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR49",
      "first-page": "279",
      "volume": "3",
      "author": "WM Fitch",
      "year": "1974",
      "unstructured": "Fitch, W. M., J. molec. Biol., 3, 279\u2013291 (1974).",
      "journal-title": "J. molec. Biol."
    },
    {
      "key": "BF260500a0_CR50",
      "doi-asserted-by": "publisher",
      "first-page": "330",
      "DOI": "10.1038/248330a0",
      "volume": "248",
      "author": "J Gralla",
      "year": "1974",
      "unstructured": "Gralla, J., and Delisi, C., Nature, 248, 330\u2013332 (1974).",
      "journal-title": "Nature"
    },
    {
      "key": "BF260500a0_CR51",
      "doi-asserted-by": "publisher",
      "first-page": "548",
      "DOI": "10.1016/S0006-291X(75)80419-0",
      "volume": "63",
      "author": "B Ricard",
      "year": "1975",
      "unstructured": "Ricard, B., and Salser, W., Biochem. biophys. Res. Commun., 63, 548\u2013554 (1975).",
      "journal-title": "Biochem. biophys. Res. Commun."
    },
    {
      "key": "BF260500a0_CR52",
      "doi-asserted-by": "publisher",
      "first-page": "703",
      "DOI": "10.1016/0022-2836(75)90147-3",
      "volume": "96",
      "author": "GM Air",
      "year": "1975",
      "unstructured": "Air, G. M., Blackburn, E. H., Sanger, F., and Coulson, A. R., J. molec. Biol., 96, 703\u2013719 (1975).",
      "journal-title": "J. molec. Biol."
    },
    {
      "key": "BF260500a0_CR53",
      "doi-asserted-by": "publisher",
      "first-page": "300",
      "DOI": "10.1021/bi00699a011",
      "volume": "13",
      "author": "F Harada",
      "year": "1974",
      "unstructured": "Harada, F., and Nishimura, S., Biochemistry, 13, 300\u2013307 (1974).",
      "journal-title": "Biochemistry"
    },
    {
      "key": "BF260500a0_CR54",
      "unstructured": "Fiers, W., et al., Abstr. 3rd int. Cong. Virol., Madrid, 17 (1975)."
    },
    {
      "key": "BF260500a0_CR55",
      "doi-asserted-by": "publisher",
      "first-page": "206",
      "DOI": "10.1038/newbio234206a0",
      "volume": "234",
      "author": "AM Weiner",
      "year": "1971",
      "unstructured": "Weiner, A. M., and Weber, K., Nature new Biol., 234, 206\u2013209 (1971).",
      "journal-title": "Nature new Biol."
    }
  ],
  "container-title": "Nature",
  "original-title": [],
  "language": "en",
  "link": [
    {
      "URL": "http://www.nature.com/articles/260500a0",
      "content-type": "text/html",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://www.nature.com/articles/260500a0.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "text-mining"
    },
    {
      "URL": "http://www.nature.com/articles/260500a0.pdf",
      "content-type": "application/pdf",
      "content-version": "vor",
      "intended-application": "similarity-checking"
    }
  ],
  "deposited": {
    "date-parts": [
      [
        2023,
        5,
        17
      ]
    ],
    "date-time": "2023-05-17T00:36:20Z",
    "timestamp": 1684283780000
  },
  "score": 1,
  "resource": {
    "primary": {
      "URL": "https://www.nature.com/articles/260500a0"
    }
  },
  "subtitle": [],
  "short-title": [],
  "issued": {
    "date-parts": [
      [
        1976,
        4,
        8
      ]
    ]
  },
  "references-count": 55,
  "journal-issue": {
    "issue": "5551",
    "published-print": {
      "date-parts": [
        [
          1976,
          4,
          8
        ]
      ]
    }
  },
  "alternative-id": [
    "BF260500a0"
  ],
  "URL": "http://dx.doi.org/10.1038/260500a0",
  "relation": {},
  "ISSN": [
    "0028-0836",
    "1476-4687"
  ],
  "subject": [],
  "container-title-short": "Nature",
  "published": {
    "date-parts": [
      [
        1976,
        4,
        8
      ]
    ]
  }
}